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At least 19 recordsLinked to original sources
PubMed1988

Trichloroacetic acid chemexfoliation (chemical peel) for extensive premalignant actinic damage of the face and scalp.

Trichloroacetic acid chemexfoliation is an effective, versatile, and safe therapeutic option for patients with extensive actinic keratoses of the face and scalp. With an experienced and skilled operator, the associated complications are rare and tend to be mild. Cosmetically, the patient not only benefits from removal of the erythematous, scaly actinic keratoses but also obtains cosmetically pleasing rejuvenation of facial skin and diminution of fine facial wrinkles. Two representative cases are presented. In comparison with other available treatment modalities, trichloroacetic acid chemexfoliation involves a shorter treatment period and wound healing time and is not dependent on patient compliance.

Aged↗
PubMedDate not supplied

Chemexfoliation as an adjunct to facial rejuvenation.

Rhytidectomy and chemexfoliation are complementary procedures. The combination of rhytidectomy and chemexfoliation as a one-stage procedure is advocated for the rejuvenation of the aging face. The advantages of the combined technique are stressed. Recognition of the facial T-zone for application of a stronger solution and occlusive mask is noted. Careful selection of patients and technical details of the procedure are outlined.

Dermatologic Surgical Procedures↗
PubMed1987

Chemexfoliation--indications and cautions.

Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trichloroacetic acid is not significantly absorbed and therefore does not produce systemic complications. Both phenol and trichloroacetic acid may produce hypertrophic scars and/or keloids and pigmentation irregularities, may accentuate preexisting abnormalities (e.g., telangiectasias, nevi, and pores), and may be associated with a flare of latent herpesvirus infection. Prolonged erythema of the treated areas and persistent rhytids have been reported with both agents.

Arrhythmias, Cardiac↗
PubMed1989

Depths of chemexfoliation induced by various concentrations and application techniques of trichloroacetic acid in a porcine model.

The depth of wounds created by various concentrations and application techniques of trichloroacetic acid (TCA) in a porcine model is evaluated. The depth of tissue necrosis increased with the concentration of TCA. Tape occlusion did not deepen the wound but rather decreased its depth. An inverse relationship of wound depth to epidermal thickness is described.

Administration, Topical↗
PubMed1991

Office dermatologic surgery and laser therapy.

As the result of a dramatic increase in the incidence of skin cancer and the need for effective outpatient surgical treatment, dermatology is now a surgical as well as a medical specialty, and many procedures are commonly performed on an outpatient basis. Mohs micrographic surgery is used to remove basal cell and squamous cell carcinomas, and the resulting cure rates are high. Excisional biopsy can facilitate the early diagnosis of melanoma, while it is still in clinical stage I. Carbon dioxide lasers are commonly used to destroy epidermal lesions and yellow light lasers to destroy hemangiomas or other vascular malformations. Facial chemical peel (chemexfoliation) with trichloroacetic acid can improve the appearance of photoaged skin.

Biopsy↗
PubMed2000

Formulation of trichloroacetic acid peeling solution: a bibliometric analysis.

Since the beginning of this century, trichloroacetic acid solutions of various concentrations have been used for chemical exfoliation. These solutions have been prepared by using four different formulas. To prepare a 50% solution, for instance, water may be added to 50 g of trichloroacetic acid crystals until 100 ml of solution is obtained (weight-to-volume solution). Alternatively, 50 g of water may be added to 50 g of trichloroacetic acid crystals (weight-to-weight solution), or 50 g of trichloroacetic acid crystals may be solved in 100 ml of water (weight-plus-volume solution). Finally, a saturated trichloroacetic acid solution (or "100% solution") may be diluted by an equal volume of water (dilution). Depending on the method used, these so-called 50% solutions contain 40 to 71 weight-to-volume percentages of trichloroacetic acid. From a review of 120 publications on trichloroacetic acid peeling that have appeared since 1926, it was concluded that the authors of 87 of these publications (73 percent) did not report their formula for the trichloroacetic acid solution. Any one of the four methods was reported to have been used by the 33 authors who did report their formula. Eight of 10 internationally reputed pharmacopeias were found not to include the formula of a trichloroacetic acid solution. Proper evaluation of results and prevention of complications of trichloroacetic acid chemexfoliation is only feasible if both the concentration and the formula of trichloroacetic acid solution are reported by the author. Practitioners who use a trichloroacetic acid solution need to establish that the concentration of the solution they apply corresponds with that of the solution reported in the literature.

Bibliometrics↗
PubMed1985

Chemical face peeling without taping.

Chemical face peeling is a simple surgical procedure which usually provides dramatic results. The potential for serious complications does exist and cautious assessment and management is essential. Aesthetically pleasing long-term results can be obtained by using chemexfoliation without taping, when employed with a "moist dressing" technique. This technique eliminates the need for repeated anesthetics and postoperative visits in order to remove facial taping, and provides an atmosphere for accelerated wound healing.

Chemexfoliation↗
PubMed1989

The Jessner's + TCA peel: a medium-depth chemical peel.

The Jessner's + TCA peel, a method of chemexfoliation, is a combination of two acidic compounds. It has been found to be an effective peeling procedure that produces a medium-depth peel for photoaging skin, actinic keratoses, and rhytides.

Administration, Topical↗
PubMed2001

Modified phenol chemical face peels: recognizing the role of application technique.

The use of phenol to achieve chemexfoliation of facial tissue, following the standard Baker-Gordon formula or modifications of that formula, can produce a range of results depending on a variety of factors. This article-based on 16 new cases of modified phenol peels, three human biopsy studies, and one triple-blind study-examines the relative roles of phenol concentration, croton oil concentration, and application technique in the production of the chemical peel result. Results of this data suggest that the application technique is more important than the concentration of phenol or croton oil and underscore the importance of standardizing the application process.

Biopsy↗
PubMed1987

The maskless chemical face peel.

The material presented in this article represents the opinions and experiences of the authors and is intended to serve as guidance for obtaining more predictable results with chemexfoliation. The maskless open technique employed has been found to be predictable, effective, and safe and to promote more rapid healing when performed as described.

Chemexfoliation↗
PubMed1980

Chemical face peel.

Chemexfoliation is extremely useful as an adjunctive tool to the cosmetic surgeon, but it is essential that the procedure not be taken lightly. Anyone can swab the face with a solution, but injudicious patient selection and inattention to details can easily lead immediately to disaster. If the patient is well informed as to expectations and the surgeon understands all the ramifications of the procedure, continued confidence in this type of surgery will remain firm. The procedure is carried out by a team approach. The surgeon applies the solution and provides the patient with postoperative instructions, but the patient then must become a part of the team and follow these instructions explicitly in order to insure the best possible surgical result. If the procedure is properly done and precautions are addressed, the rewards of a refined facial appearance can be enjoyed by the patient, and the surgeon may experience a true sense of accomplishment.

Adult↗
PubMed1993

A primer of facial chemical peel.

Facial chemical peel encompasses a plethora of procedures or techniques and so may be confusing. This should not blunt one's enthusiasm for what chemexfoliation can achieve. With the use of TCA, chemical peel is a safe, effective, elegant, and simple method for treating some common problems of photoaged, fair skin (Table 7). When a standardized technique is used, it is possible to quantify the therapeutic effects and to predict the outcome reliably. Variations of chemical peel will be used as clinicians try to achieve better results. If possible, variations from standard techniques should be scientifically studied and quantified to establish their safety and efficacy. The goal of chemical face peeling is not simply to achieve a deep or longer-lasting peel. The highest concentrations of TCA and phenol may cause full-thickness facial chemical burns and leave long-lasting scars. Therefore, variations on standard techniques provide only subjective, difficult-to-measure benefits. Conversely, standardized testing on the facial skin of patients is difficult and thus we chose an animal model. Clinicians, especially dermatologists, who want to perform chemical peel should know the indications. Using the procedures described here and in other articles, one can safely and reliably undertake facial chemical peel.

Chemexfoliation↗