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At least 19 recordsLinked to original sources
PubMed2002

Effect of response-independent candy on responding maintained by candy using a novel model of commodity acquisition and consumption in nonhuman primates.

Ingestive behavior consists of appetitive or foraging behavior, i.e., "acquisition," followed by consummatory behavior. Responding of six adult rhesus monkeys, living in three-chambered enclosures, was studied under an operant chain schedule that simulated commodity acquisition and commodity consumption. Responding during the initial acquisition component was reinforced by stimuli paired with that commodity, while responding during the following consumption component was reinforced with that commodity. Throughout the 10-h experimental day, monkeys experienced multiple candy (plain M & Ms) and fruit-drink (Kool-Aid) sessions in different end chambers. The effects of response-independent candy reinforcement, in the context of extinction, were examined when monkeys received a daily food ration of 8 or 20 chow. Response-independent candy increased responding during the acquisition components of candy sessions when monkeys received a daily food ration of 8 chow but not when the food ration was 20 chow. Furthermore, response-independent candy increased candy choice over fruit-drink during choice opportunities and increased the length of time spent in the candy chamber when the candy stimulus lights were illuminated under both food ration conditions, i.e., location preference. The present procedure, which combines operant and place preference measures of commodity acquisition, when used in combination with methods of studying reinstatement of responding, may prove useful in analyzing factors affecting relapse.

Animals↗
PubMed2007

Effects of calcium on the erosive potential of acidic candies in saliva.

Theoretical calculations have shown that acidic candies may be potentially erosive upon consumption. However, little is known about the protective effect of adding calcium to potentially erosive candies and about the protective effects of saliva that cannot be fully accounted for by theoretical calculations. Therefore, the aims of this study were to (1) determine the erosive potential of acidic candies with and without calcium and (2) to determine differences between theoretically calculated erosive potential and actual erosive potential in saliva. Twenty healthy test persons sucked acidic candy with and without calcium while their whole saliva was collected into a closed system at different times: baseline, candy-stimulated, and post-stimulated. The erosive potential of the candy was evaluated from candy-induced changes in saliva degree of saturation with respect to hydroxyapatite (HAp) and directly by dissolution of HAp crystals in candy-stimulated saliva. The results showed that similar salivary stimulation was obtained with both candies. The modified candy released more than 13 mmol/l of calcium into saliva, resulting in a lower critical pH, and considerably lower erosive potential than the control (p < 0.001). Although a significant correlation was obtained between theoretical calculation of DS(HAp) and dissolution of HAp crystals (r(s) = 0.65; p < 0.001), many samples obtained by sucking modified candy showed no signs of HAp dissolution in spite of being undersaturated. We conclude that saturation levels and critical pH may not fully reflect when dental erosion is expected to occur in saliva and that calcium addition reduces the erosive potential of acidic candies.

Adult↗
PubMed2002

Effects of buprenorphine on candy and sweetened fluid self-administration by rhesus monkeys.

RATIONALE: . Previous studies have shown that buprenorphine differentially suppresses the reinforcing effects of different drugs (cocaine, alfentanil), drug versus nondrug reinforcers (food, drug), and the same reinforcer (food) maintained under different schedules of reinforcement. OBJECTIVES: The purpose of the present study was to determine whether buprenorphine (0.03, 0.1, 0.3 mg/kg) differentially affects candy versus sweetened fluid self-administration. The hypotheses were that (1) candy would maintain higher rates of responding and would be chosen on more occasions than sweetened fluid, and (2) buprenorphine would produce smaller disruptions in responding for the more-preferred reinforcer. METHODS: During separate sessions, rhesus monkeys self-administered candy alone, sweetened fluid alone, or had the opportunity to choose between candy and sweetened fluid. Monkeys responded under a second order, two-chain schedule of reinforcement. RESULTS: Candy was a more-preferred reinforcer than sweetened fluid. Buprenorphine significantly decreased rates of responding for fluid, but increased rates of responding for candy. Although buprenorphine significantly decreased both candy and fluid intake, it produced a more robust, and longer-lasting suppression of sweetened-fluid intake than candy. Choice to self-administer candy or fluid was not affected by buprenorphine. CONCLUSIONS: These results demonstrate that behavior maintained by a less-preferred reinforcer is more easily disrupted by buprenorphine than is behavior maintained by a more-preferred reinforcer.

Analysis of Variance↗
PubMedDate not supplied

Effects of sucking acidic candy on whole-mouth saliva composition.

Limited information is available on the effects of sucking acidic candies on saliva composition and the protective role of saliva in this relation. Therefore the aim of this study was to determine salivary effects of sucking acidic candies in vivo in relation to individual variations in whole-saliva flow rate (WSFR) and buffer capacity (WSbeta). Ten healthy young males (24 +/- 2 years) sucked a rhubarb-flavoured acidic hard-boiled candy with tartaric acid available on the Danish market. The whole saliva was collected into a closed system, regarding CO2, at different times as follows: firstly, unstimulated saliva for 5 min (baseline), secondly stimulated saliva for 4 min upon sucking the candy, and finally post-stimulated saliva for 10 min. Saliva pH was determined on a blood gas analyser and WSbeta was estimated from the saliva bicarbonate concentration obtained by the analyser and by ionic balance calculation. The erosive potential of the candy in saliva was estimated from the saliva pH values and degree of saturation with respect to hydroxyapatite (DS(HAp)). The results showed that saliva pH dropped from 6.5 (baseline) down to 4.5 at the fourth minute of sucking the candy, and returned to pH 6.5 five minutes after stimulation (post-stimulated). DS(HAp) decreased upon sucking the candy and saliva from all subjects became undersaturated with respect to HAp. Significant positive correlations were obtained between pH and WSFR (r(s) = 0.47; p < 0.05) and between pH and WSbeta (r(s) = 0.65; p < 0.01). In relation to WSbeta we found that 70% of the buffer capacity originating from the bicarbonate buffer system upon sucking the candy was exerted as phase buffering. We conclude that sucking this type of acidic candies changes whole-mouth saliva composition so that it may have erosive potential and that high WSFR and WSbeta have protective effects against these salivary changes.

Acids↗
PubMed2005

Does lemon candy decrease salivary gland damage after radioiodine therapy for thyroid cancer?

UNLABELLED: Salivary gland dysfunction is one of the common side effects of high-dose radioiodine therapy for thyroid cancer. The purpose of this study was to determine whether an early start of sucking lemon candy decreases salivary gland injury after radioiodine therapy. METHODS: The incidence of the side effects of radioiodine therapy on the salivary glands was prospectively and longitudinally investigated in 2 groups of patients with postsurgical differentiated thyroid cancer with varying regimens for sucking lemon candy. From August 1999 to October 2000, 116 consecutive patients were asked to suck 1 or 2 lemon candies every 2-3 h in the daytime of the first 5 d after radioiodine therapy (group A). Lemon candy sucking was started within 1 h after radioiodine ingestion. From November 2000 to June 2002, 139 consecutive patients (group B) were asked to suck lemon candies in a manner similar to that of group A. In the group B, lemon candies were withheld until 24 h after the ingestion of radioiodine. Patients with salivary gland disorders, diabetes, collagen tissue diseases, or a previous history of radioiodine therapy or external irradiation to the neck were excluded. Thus, 105 patients in group A and 125 patients in group B were available for analysis. There were no statistical differences in the mean age (55.2 y vs. 58.5 y), average levels of serum free thyroxine (l-3,5,3',5'-tetraiodothyronine) (0.40 ng/dL vs. 0.47 ng/dL), and the mean dose of (131)I administered (3.96 GBq vs. 3.87 GBq) between the 2 groups. The onset of salivary side effects was monitored during hospital admission and regular follow-up on the basis of interviews with patients, a visual analog scale, and salivary gland scintigraphy using (99m)Tc-pertechnetate. When a patient showed a persistent (>4 mo) dry mouth associated with a nonfunctioning pattern on salivary gland scintigraphy, a diagnosis of xerostomia was established. RESULTS: The incidences of sialoadenitis, hypogeusia or taste loss, and dry mouth with or without repeated sialadenitis in group A versus group B were 63.8% versus 36.8% (P < 0.001), 39.0% versus 25.6% (P < 0.01), and 23.8% versus 11.2% (P < 0.005), respectively. Permanent xerostomia occurred in 15 patients in group A (14.3%) and 7 patients in group B (5.6%) (P < 0.05). In both groups, bilateral involvement of the parotid gland was the most frequently seen and was followed by bilateral involvement of the submandibular gland. CONCLUSION: An early start of sucking lemon candy may induce a significant increase in salivary gland damage. Lemon candy should not be given until 24 h after radioiodine therapy.

Administration, Oral↗
PubMed1992

Candy cigarettes: do they encourage children's smoking?

Candy and bubble gum cigarettes are packaged to resemble cigarette brands, and so they may encourage young children to smoke. Two studies of the role of these products in the development of children's attitudes and behaviors toward smoking were conducted. In the first study, six focus group interviews were conducted with 25 children in three age groups (4 through 5, 6 through 8, and 9 through 11 years old). Children in each group were shown five candy and snack foods and asked about their opinions and experiences with each item. In the second study, 195 seventh-grade students in a southeastern city school system were surveyed about their cigarette smoking and candy cigarette use. In the focus groups, candy cigarettes were recognized by most children. Young children played with the candy cigarettes more than with other candy or snack items and made general references to smoking behaviors. Older children made favorable references to smoking behavior; most knew which stores sold candy cigarettes, and many had chosen to buy and use these items, despite parental disapproval. Candy cigarettes may play a role in the development of children's attitudes toward smoking as an acceptable, favorable, or normative behavior. Elimination of these products should be part of efforts to prevent initiation of smoking by children.

Adolescent↗
PubMed1992

Triacetin as food additive in gummy candy and other foodstuffs on the market.

The qualitative and quantitative analytical methods were proposed for the simple and rapid determination of triacetin (TAc) in commercial gummy candies and other foodstuffs by gas chromatography (GC), thin layer chromatography (TLC) and infrared spectroscopy (IR). Each extract from the samples was obtained by pretreatment of the foodstuffs as follows: (A) Gummy candy was dissolved in warm water and the solution was extracted with chloroform. The organic (chloroform) layer was separated. (B) Samples (such as ice cream) containing substantial water were mixed with anhydrous Na2SO4 and stirred to sandy appearance and dried. The residue was homogenized with ether, followed by centrifuging, and the organic (ether) layer was separated. (C) Dried samples (such as chocolate and cookie) were smashed, homogenized with ether, and followed by centrifuging, and the organic (ether) layer was separated. (D) Candy was dissolved in warm water and the solution was extracted with ether. The organic (ether) layer was separated. Each organic layer from (A)-(D) was washed with 10% NaHCO3 and evaporated. The residue containing TAc was dissolved in dichloromethane. The extract obtained was subjected to column chromatography on silica gel. The fractions containing TAc were employed in GC with 25% PEG-20M column, TLC, and IR analyses. Recovery of TAc from gummy candy was 99.1 +/- 3.0% and those from other foodstuffs ranged from was 82.1 to 99.4% by GC. Detection limit by this method was 10 ppm. TAc was found to contain at a level as high as 550 ppm in one domestic gummy candy. On the other hand, one imported gummy candy contained no more than 20 ppm of TAc gummy candy.

Beverages↗
PubMed1988

Should we X-ray Halloween candy? Revisited.

The well-intentioned program of X-raying Halloween candy is costly. The annual expense to the 3 local hospitals in the Reno/Sparks area was $1625.62. The price to X-ray each bag ranged from $2.01 to $5.23 (average $3.38). On the basis of our total regional population statistics, the nation could be spending as much as $0.8-$1.4 million to screen Halloween candy. Radiographic screening of Halloween candy is not effective. Of the 394 X-rays taken in the 3 local hospitals, and the 669 taken in 18 outlying hospitals, no films were positive for hidden radio-opaque forein bodies. Not only is X-raying Halloween candy costly and ineffective, it also creates several problems. Children taking their candy to the hospital on Halloween night risk involvement in traffic accidents. The implication that X-rayed candy is "safe" carries potential liability. Additional drawbacks and risks arise from crowds composed mostly of children in the Radiology Dept and Emergency Room, and from disruption of vital hospital functions. In October, 1986, a program for community education and cooperation among all 3 area hospitals was developed. No X-rays were offered in the Reno/Sparks area. There were no police reports of contaminated candy for this Halloween following implementation of this program, compared to 4 reports for the preceding 2 years.

Candy↗
PubMed1968

Effects of candy and social reinforcement, instructions, and reinforcement schedule leaning on the modification and maintenance of smiling.

Two retarded boys exhibited abnormally low rates of smiling. In Exp. I, the frequency of a boy's smiling was first increased with candy reinforcement, but the frequency of the response did not decrease when candy reinforcement was terminated. When the subject wore a sign designed to make social interactions contingent on not-smiling, the frequency of smiling decreased. The sign was then changed to make social interactions contingent on smiling and the rate of smiling increased. In Exp. II, a second boy initially never smiled. Establishment of a contingency for candy reinforcement did not increase this zero response rate. Instructing the child to smile initially increased smiling, but the instructions then became progressively more ineffective. Candy reinforcement increased the rate of smiling to a normal range, but the rate of the response promptly decreased when this reinforcement was discontinued. Continuous candy reinforcement was again employed to increase the response rate and then progressively leaner schedules of variable-ratio candy reinforcement were employed. Consequently, the rate of smiling did not decrease when candy reinforcement was again eliminated. Subsequently, signs were employed to regulate social interactions and the rate of smiling was shown to be controlled by these interactions serving as reinforcers.

Journal Article↗
PubMed1989

Plaque fluid pH, calcium and phosphorus responses to calcium food additives in a chewable candy.

Fourteen subjects between 7 and 17 years of age with an equal distribution of low and high caries activity were given: (1) a 10% sucrose rinse, (2) a reference candy, (3) a reference candy with 3% dicalcium phosphate dihydrate, and (4) a reference candy with 0.75% calcium lactate on four different occasions. Plaque samples were collected before and at 15-min intervals after the sucrose rinse or food challenge for a period of 1 h on each occasion. Plaque samples were centrifuged and the extracellular plaque fluid analysed by a microtechnique for pH, total calcium and inorganic phosphorus concentration. There was no significant increase in calcium and phosphorus in plaque fluid for the group using candy with added calcium compared to the reference candy or sucrose rinse. There was no significant difference between the measurements in subjects grouped as caries active or inactive. The results suggest no benefit can be expected from adding dicalcium phosphate dihydrate and calcium lactate to candy to decrease demineralization during a cariogenic challenge.

Adolescent↗
PubMed2005

Effects of sucking acidic candies on saliva in unilaterally irradiated pharyngeal cancer patients.

Patients who have received radiation therapy on the head and neck area often use acidic candies to relieve symptoms of dry mouth. Therefore, the aim of this study was to determine the erosive potential in relation to teeth of an acidic candy in 10 such patients. The patients sucked the candy while their whole saliva was collected into a closed system at different times: baseline, candy-stimulated, and post-stimulated. The erosive potential of the candy was evaluated from candy-induced changes in saliva degree of saturation with respect to hydroxyapatite (HAp). Previously published normative values were used for comparison. The results showed that saliva became significantly more undersaturated with respect to HAp in irradiated patients, and failed to return to baseline values during the post-stimulatory period, which it normally does in healthy individuals. Thus, prevention of dental breakdown in these patients should involve counseling regarding choice of stimulant for dry mouth relief.

Acids↗
PubMedDate not supplied

The effects of D-amphetamine on responding for candy and fruit drink using a fixed ratio and a progressive ratio schedule of reinforcer delivery.

The first purpose of this study was to compare the effects of D-amphetamine (AMPH) on operant responding reinforced under fixed ratio (FR) or progressive ratio (PR) schedules of reinforcement, testing the hypothesis that responding reinforced under a PR operant schedule would be disrupted by lower doses of AMPH than responding reinforced under a FR operant schedule. The second purpose of this study was to test the generalizability of the first hypothesis by comparing the effects of AMPH on responding reinforced by two different reinforcers under both FR and PR operant schedules. Rhesus monkeys had five to six candy and five to six fruit drink sessions per day, and could receive two reinforcers per session. Responding was initially reinforced under a PR procedure, such that the ratio size increased with each subsequent session. The parameters of the PR schedule were individually selected so that monkeys consumed a similar number of candy and fruit-drink reinforcers each day. The effects of oral AMPH (0.5, 0.75, 1.0 mg/kg) on responding were assessed. Responding was then stabilized using a FR schedule with parameters individually selected so that monkeys consumed a similar number of candy and fruit-drink reinforcers each day, and the effects of oral AMPH were again assessed. The PR breakpoint was significantly greater for candy than fruit-drink. AMPH produced dose-related decreases in both candy and fruit-drink intake, but each AMPH dose decreased the number of fruit-drink deliveries to a greater extent than the number of candy deliveries. The results failed to support the hypothesis that responding under PR schedules of reinforcement would be disrupted by lower doses of AMPH.

Animals↗
PubMed2004

Flavor release and perception in hard candy: influence of flavor compound-compound interactions.

The influence of flavor compound-compound interactions on flavor release properties and flavor perception in hard candy was investigated. Hard candies made with two different modes of binary flavor delivery, (1) L-menthol and 1,8-cineole added as a mixture and (2) L-menthol and 1,8-cineole added separate from one another, were analyzed via breath analysis and sensory time-intensity testing. Single-flavor candy containing only L-menthol or 1,8-cineole was also investigated via breath analysis for comparison. The release rates of both L-menthol and 1,8-cineole in the breath were more rapid and at a higher concentration when the compounds were added to hard candy separate from one another in comparison to their addition as a mixture (conventional protocol). Additionally, the time-intensity study indicated a significantly increased flavor intensity (measured as overall cooling) for hard candy made with separate addition of these flavor compounds. In conclusion, the flavor properties of hard candy can be controlled, at least in part, by flavor compound-compound interactions and may be altered by the method of flavor delivery.

Adult↗
PubMed2006

The office candy dish: proximity's influence on estimated and actual consumption.

OBJECTIVE AND PURPOSE: Although there is increasing interest in how environmental factors influence food intake, there are mixed results and misunderstandings of how proximity and visibility influence consumption volume and contribute to obesity. The objective of this paper is to examine two questions: first, how does the proximity and salience of a food influence consumption volume? Second, are proximate foods consumed more frequently because they are proximate, or are they consumed more frequently because people lose track of how much they eat? RESEARCH METHODS AND PROCEDURES: The 4-week study involved the chocolate candy consumption of 40 adult secretaries. The study utilized a 2 x 2 within-subject design where candy proximity was crossed with visibility. Proximity was manipulated by placing the chocolates on the desk of the participant or 2 m from the desk. Visibility was manipulated by placing the chocolates in covered bowls that were either clear or opaque. Chocolates were replenished each evening, and placement conditions were rotated every Monday. Daily consumption was noted and follow-up questionnaires were distributed and analyzed. RESULTS: There were main effects for both proximity and visibility. People ate an average of 2.2 more candies each day when they were visible, and 1.8 candies more when they were proximately placed on their desk vs 2 m away. It is important to note, however, that there was a significant tendency for participants to consistently underestimate their daily consumption of proximately placed candies (-0.9) and overestimate their daily consumption of less proximately placed candies (+0.5). DISCUSSION: These results show that the proximity and visibility of a food can consistently increase an adult's consumption of it. In addition, these results suggest that people may be biased to overestimate the consumption of foods that are less proximate, and to underestimate those that are more proximate. Knowing about these deviation tendencies is important for those attempting effectively monitor their consumption of fat and sugar.

Adult↗
PubMed1993

A prospective study of postpartum candy gift net weight: correlation with birth weight.

This study assesses the widely held but previously untested hypothesis that the net weight of postpartum candy gifts from parents to delivery suite and postnatal ward staff is proportional to their neonates' birth weight. Midwives at Musgrove Park Hospital in Taunton, Somerset, United Kingdom were requested to record the details of all candy gifts received over a 6-month period in 1992. Only 39 candy gifts from 1491 deliveries were documented, with a mean net weight of 416 g. The coefficient of correlation between candy weight and birth weight was 0.1477 (P = .2). The basis for the association is multifactorial. Socioeconomic and prematurity-related factors were responsible for poor candy giving following low birth weight deliveries. In contrast, factors related to the etiology and psychology of obesity and diabetes were implicated in generous candy giving by the high birth weight population.

Birth Weight↗
PubMed1996

Hyperactivity: is candy causal?

Adverse behavioral responses to ingestion of any kind of candy have been reported repeatedly in the lay press. Parents and teachers alike attribute excessive motor activity and other disruptive behaviors to candy consumption. However, anecdotal observations of this kind need to be tested scientifically before conclusions can be drawn, and criteria for interpreting diet behavior studies must be rigorous. Ingredients in nonchocolate candy (sugar, artificial food colors), components in chocolate candy (sugar, artificial food colors in coatings, caffeine), and chocolate itself have been investigated for any adverse effects on behavior. Feingold theorized that food additives (artificial colors and flavors) and natural salicylates caused hyperactivity in children and elimination of these components would result in dramatic improvement in behavior. Numerous double-blind studies of the Feingold hypothesis have led to the rejection of the idea that this elimination diet has any benefit beyond the normal placebo effect. Although sugar is widely believed by the public to cause hyperactive behavior, this has not been scientifically substantiated. Twelve double-blind, placebo-controlled studies of sugar challenges failed to provide any evidence that sugar ingestion leads to untoward behavior in children with Attention-Deficit Hyperactivity Disorder or in normal children. Likewise, none of the studies testing candy or chocolate found any negative effect of these foods on behavior. For children with behavioral problems, diet-oriented treatment does not appear to be appropriate. Rather, clinicians treating these children recommend a multidisciplinary approach. The goal of diet treatment is to ensure a balanced diet with adequate energy and nutrients for optimal growth.

Attention Deficit Disorder with Hyperactivity↗
PubMed2001

Effect of iron-fortified candies on the iron status of children aged 4-6 y in East Jakarta, Indonesia.

BACKGROUND: Iron deficiency anemia is the most prevalent nutrition problem in young children. One possible strategy to prevent iron deficiency anemia in this population group is the fortification of affordable food. OBJECTIVE: This study was designed to assess whether iron-fortified candies can improve iron status and are acceptable to children aged 4-6 y. DESIGN: A double-blind, placebo-controlled intervention study was conducted in Jakarta, INDONESIA: The children were randomly assigned to 1 of 2 treatment groups: a fortified group (n = 57) and a placebo group (n = 60). Every week for 12 wk, 30 g (10 pieces) candy was given to the children. The candy given to the fortified group contained 1 mg elemental Fe/g and very small amounts of other vitamins and minerals. RESULTS: The hemoglobin concentration of the fortified group increased by 10.2 g/L (95% CI: 8.3, 12 g/L) whereas that of the placebo group increased by 4.0 g/L (2.0, 6.0 g/L; P < 0.001). Anemia prevalence decreased from 50.9% at the start of the intervention to 8.8% after 12 wk of intervention in the fortified group (P < 0.001) and from 43.3% to 26.7% in the placebo group (P < 0.05). After 12 wk of intervention, the serum ferritin concentration was 71% higher than at baseline in the fortified group and 28% higher in the placebo group (P < 0.001). Acceptability of the iron-fortified candies was good. The per capita cost of the supplement was approximately US$0.96-1.20 for the 12 wk of intervention. CONCLUSION: Iron-fortified candies were effective for improving the iron status of young children and might be an affordable way to combat iron deficiency in children of low-to-middle income groups.

Anemia, Iron-Deficiency↗