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At least 19 recordsLinked to original sources
PubMed2000

Epidemiology of eczematous cheilitis at a tertiary dermatological referral centre in Singapore.

In a retrospective epidemiologic study of 202 patients with eczematous cheilitis attending a patch test clinic, females (182 (90%)) predominated over males (20 (10%)). The mean age of our patients was 30.9 years. There was no significant difference between the mean age of females (31 years) presenting with cheilitis compared to males (29 years). Endogenous cheilitis (53%) was the commonest diagnosis, followed by allergic contact dermatitis (34%) and irritant contact dermatitis (5.4%). A personal history of atopy was recorded in 33%. There was no significant difference in the prevalence of atopy between the sexes or among the diagnoses. The mean duration of cheilitis was 16.4 months. The duration was significantly longer in males (29 months) than in females (15 months) (p=0.004). The mean number of positive patch test reaction in patients with allergic contact cheilitis (2.8) was significantly higher than in those with irritant contact cheilitis (0.2) (p = 0.012) or endogenous cheilitis (0.5) (p = 0.00). The commonest cause of allergic contact cheilitis were lip cosmetics, including lipsticks and lipbalms, followed by toothpastes. The commonest cause of irritant contact cheilitis was lip-licking, lipsticks and medication. In 81/202 (40%) patients, 1 or more causes of contact cheilitis could be ascertained. In females, lip cosmetics were the commonest cause, accounting for 54% (44/81) of cases. Toothpastes accounted for 21% (17/81), followed by topical medication 7% (6/81). For males, toothpastes were the commonest cause of allergic contact cheilitis. Ricinoleic acid and the patient's own lip preparations were the commonest relevant contact allergens.

Adult↗
PubMed2002

[Glandular cheilitis. 2 case reports].

BACKGROUND: Glandular cheilitis (GC) is a rarely recognized disease of the accessory salivary glands of the lips, particularly of the lower lip. Clinically, three variants have been described: cheilitis glandularis simplex, cheilitis glandularis suppurativa, and cheilitis glandularis apostematosa. Most cases are diagnosed as the simple form of glandular cheilitis, which is characterized by enlarged excretory ducts, induration, and enlargement of the salivary glands as well as production of a rather mucopurulent saliva. CASE REPORTS: Two patients are described who revealed the characteristic changes of cheilitis glandularis simplex (case 1, 75-year-old male patient; case 2, 83-year-old female patient). In case 1 the patient developed a retention cyst of the upper lip probably as a consequence of GC. DIAGNOSIS: Histologically, ectasia of glandular ducts and chronic sialadenitis are typical features. Therapy formerly consisted of antibiotics and locally applied corticosteroids; an optimal oral hygiene, however, is mandatory. Advanced stages have to be treated surgically. Glandular cheilitis has been considered a precancerous lesion, although no definite scientific proof has ever been presented. Cheilitis granulomatosa, cheilitis exfoliativa, and self-induced changes (Munchausen syndrome) have to be considered in the differential diagnosis of glandular cheilitis.

Aged↗
PubMed1984

[Clinical, etiopathogenetic and anatomopathological considerations in primary cheilitis].

Among the wide range of stomatitis and mucositis there are lesions, defined as primary cheilitis, affecting mainly the lips. Specific topographic and structural features of the involved area determine their appearance. The Authors revient contact-related cheilitis, actinic-related cheilitis, glandular and suppurative cheilitis, granulomatous and exfoliative cheilitis. They point out the principle clinical, etiopathogenetic and histopathologic features. From their overview it arises, that in modern literature, funy detailed contributions are definitively lacking. Symptomatic medical treatments are a clear reflection of many etiological doubis. Surgical therapy is advised only in chronic actinic-related cheilitis and in deep-rooted glandular cheilitis. In granulomatous cheilitis surgical treatment is indicated once a permanent lip deformity occurs.

Cheilitis↗
PubMed1984

[Factitious crusting cheilitis].

The authors report 4 cases of factitious crusting cheilitis seen in young women. The lesions are crusty, yellowish or even black, forming as a mould casting the lip. The crusts are sometimes very thick just as an oyster-shell. When removed the underlying mucosa appears either normal or erosive and the crusts reappear rapidly. Emotional factors and personality disturbances are often present. Most probably the crusts are the result of a traumatic mechanism induced by chewing or sucking the lip. In the 4 reported patients the clinical aspect and the psychological status of the patients are similar, the 4 of them being not at all bothered by their cheilitis. The factitious keratotic cheilitis has to be differentiated from other cheilitis induced by Candida albicans (although Candida albicans may superinfect any cheilitis) or by an actinic phenomenon, from glandular cheilitis (of the Puente-Acevedo or of the Volkmann type) and from dermatitis localized on the lips. In some instances an exfoliative cheilitis may also to be of factitious origin. The factitious origin of such a cheilitis is always difficult to demonstrate but its possibility should be kept in mind.

Adolescent↗
PubMed1983

Factitious cheilitis.

Six patients (four male and two female) with factitious cheilitis are described. All had personality disturbances as well as crusted lip lesions that varied in severity from thin serous crusts to thick hemorrhagic crusts. This entity must be distinguished from infectious cheilitis, contact cheilitis, actinic cheilitis, photosensitivity dermatoses, exfoliative cheilitis, and cheilitis glandularis on the basis of the history and laboratory evaluation.

Adult↗
PubMed2000

[Atopic cheilitis in children: the risk factors and clinical symptoms].

General and local factors affecting the development of atopic cheilitis, alone and in association with disseminated neurodermatitis, have been studied. Health disorders were more incident in children with cheilitis concomitant with disseminated neurodermatitis than in those with cheilitis alone (without other skin involvement). The most significant general risk factors are an unfavorable course of antenatal development, exudative catarrhal diathesis, food allergies, gastrointestinal diseases, intestinal dysbacteriosis. Local risk factors were impaired joining of the lips and disordered nasal breathing, long soother sucking, harmful habits, and maxillodental abnormalities. Clinical symptoms in isolated cheilitis and cheilitis concomitant with disseminated neurodermatitis are similar, but cheilitis associated with disseminated neurodermatitis runs a more severe course.

Adolescent↗
PubMed1992

[Schizophrenia and factitious cheilitis: a case report].

Factitious Cheilitis is a rare skin disorder which has been seen in patients with emotional disturbances, particularly in cases with neurotic and personality disorders. However, there have been no reports of factitious cheilitis seen in cases of schizophrenia. This study reports on a case of schizophrenic disorder, where the patient was observed to develop factitious cheilitis whilst subject to unstable psychiatric conditions. The case reported here is of a 59 year-old female widow, who has experienced the delusion of being controlled, the delusion of being possessed. Been subject to auditory hallucination and vague somatic pain for eight years and had a very poor psychotropic drug compliance. Observation revealed frequent licking of the lips unrelated to drug-induced dyskinesia, but as a possibly linked response to hallucination whilst subject to an intense unstable emotional and painful state. Factitious cheilitis was proved with biopsy of the lips and pathological findings of acanthosis, hyperkeratosis and parakeratosis. After psychiatric and dermatologic care, her cheilitic condition improved. This study demonstrates that factitious cheilitis can be seen in a schizophrenic patient, specifically where hallucination and emotional instability coupled with long-term licking of the lips can result in factitious cheilitis. The relationship of skin disorder and psychiatric illness is discussed.

Cheilitis↗
PubMed1999

Cheilitis: analysis of 75 cases referred to a contact dermatitis clinic.

BACKGROUND: Cheilitis is a common problem, the cause of which is often obscure. OBJECTIVE: Data on 75 cases of recalcitrant cheilitis were analyzed. These had been referred to a tertiary care center. METHODS: Each of the 75 patients had undergone a detailed history, physical examination, and patch tests. RESULTS: Of the patients, 53 were female (67%), and the age range was 9 to 79 years. Of the cases, 36% included irritant contact dermatitis (ICD), 25% included allergic contact dermatitis (ACD), 19% were attributed to atopic eczema, and in 9% the dermatitis was of unknown cause. Nine percent were noneczematous. The materials causing ACD were medicaments applied to the lips, lipstick ingredients, sunscreen agents, toothpaste ingredients, colophony in dental floss and toothpicks, nail varnish, cosmetics, and nickel in the mouthpiece of a flute. CONCLUSION: The most common cause of cheilitis was irritation, frequently caused by liplicking. About one quarter was caused by ACD. Medicaments, lipsticks, sunscreens, and toothpaste were the most common allergens. Atopic eczema is a commonly overlooked cause of cheilitis. However, there is a troublesome group of patients, 9% in this series, who are often severely affected, but the cause of their cheilitis remains obscure.

Adolescent↗
PubMed2002

Topical 5% imiquimod for the therapy of actinic cheilitis.

BACKGROUND: Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECTIVE: Our aim was to review the results in patients who had been treated for actinic cheilitis with imiquimod cream. METHODS: A review identified 15 patients with biopsy-proven actinic cheilitis who had been treated with topical imiquimod 3 times weekly for 4 to 6 weeks. All patients with histories consistent with facial herpes simplex or documented prior facial herpes simplex eruptions were treated with oral valcyclovir, 1 g/d, during imiquimod therapy. RESULTS: All 15 patients showed clinical clearing of their actinic cheilitis at 4 weeks after discontinuation of the topical imiquimod. Sixty percent of the patients experienced a moderate to marked increased local reaction consisting of increased erythema, induration, and erosions or ulcerations, which in some cases continued through the period of therapy. CONCLUSION: Imiquimod appears to have a role in the treatment of actinic cheilitis. However, the dose and duration of therapy, as well as the long-term efficacy, need to be established; and local reactions are to be expected and may not improve during therapy.

Acyclovir↗
PubMed1986

Angular cheilitis: a clinical and microbial study.

The purpose of this prospective study was to re-examine the relative importance of various factors in the pathogenesis of angular cheilitis. Sixty-four patients with cheilitis were examined clinically and microbiologically. In addition, a subsample of 23 patients was examined for serum iron and transferrin. The clinical appearance of the lip lesions fell into 4 categories. A ground rhagad at the corner of the mouth involving adjacent skin, was the most frequent type among dentate patients, whereas among denture wearers a deep lesion following the labial marginal sulcus was frequently observed. Dentate patients and denture wearers with cheilitis often had atopic constitution or cutaneous diseases. Pathogenic microorganisms were cultured from the lesions in all 64 patients; Staphylococcus aureus in 40 patients and Candida albicans in 45. The results of this study indicate a correlation between angular cheilitis and pathogenic microorganisms. Furthermore, among dentate patients, a correlation exists between cutaneous discomfort and angular cheilitis. Other etiological factors suggested for this disorder were found to be of subordinate importance.

Adolescent↗
PubMed2002

[Cheilitis].

Cheilitis is clinically characterised by an acute or chronic inflammatory state of the lips, limited to the vermillion border. The term "angular" cheilitis applies to localise bilateral lesions of the angles of the mouth. Acute cheilitis is erythematous or erosive, accompanied by a stinging sensation. Chronic cheilitis is for the most part erythemato-squamous, and is often asymptomatic. The classification of cheilitis is based on the aetiology, being most often an allergy, an infection or a physical irritation, potentially favourised by particular anatomical conditions. However, the distinction between the diverse types is sometimes blurred as diverse causes can co-exist.

Cheilitis↗
PubMed1975

[Cheilitis caused by photosensitization].

Many clinical entities show manifestations in the lips and sometimes such localization is eminent. In the photodermatosis there are different degrees of compromise of the lips. In the Polimorphus Light Eruption the cheilitis is a very common feature in the tropics and sometimes is the only manifestation of the disease for some time, or is accompanied by scant elements in the face and forearms. It is necessary to distinguish between chronic Antinic Cheilitis and the Eczematous cheilitis produced by the photosensitizing action of very well known substances contained in lip-sticks. The exfoliative cheilitis sometimes is found in atopic patients or patients with emotional disturbances. The Cheilitis present in patients with actinic chronic dermatitis are able to transform in Epithelioms.

Adult↗
PubMed1979

The actinic cheilitis of hereditary polymorphic light eruption.

Sixty-four North American Indians with hereditary polymorphic light eruption (HPLE), or a family history of HPLE, had chronic, recurrent, exudative, and exfoliative cheilitis. Fifty-two had the cheilitis by the age of 10 years. Microscopically, the epithelium was either thickened, or thinned and covered by a thick crust. The dermis had a dense infiltration of inflammatory cells, mostly lymphocytes and plasma cells. The condition was not premalignant. The HPLE has to be differentiated from the chronic actinic cheilitis caused by long exposure to sunlight with out any element of hypersensitivity. The latter is potentially premalignant. Chronic recurrent actinic cheilitis associated with hereditary polymorphic light eruption appears to be a specific characteristic of photosensitivity occurring in American Indians. Plasma cell infiltration is not specific for either type of cheilitis.

Adolescent↗
PubMed2002

Cheilitis granulomatosa: overview of 13 patients with long-term follow-up--results of management.

BACKGROUND: Cheilitis granulomatosa, often regarded as a subtype of orofacial granulomatosis, is characterized by recurrent or persistent swelling of one or both lips. Classically, a non-necrotizing granulomatous inflammation is seen at histologic examination. Although a relationship has been proposed between Melkersson-Rosenthal syndrome (and the monosymptomatic form, cheilitis granulomatosa) and Crohn's disease on the basis of the orofacial swelling and similar histology, several studies of Melkersson-Rosenthal syndrome have not found an association with Crohn's disease. METHODS: The clinical features, histopathology, association with Crohn's disease, and results of nonsurgical and surgical therapy in 13 patients with cheilitis granulomatosa were investigated in a retrospective case study with a mean follow-up period of 8.2 years. RESULTS: There was a low chance of developing Crohn's disease. Most patients in this study responded to nonsurgical treatment modalities. Patients with deterioration of lip swelling usually responded to intralesional injections with triamcinolone or to short courses of systemic glucocorticoids. Nonsteroidal systemic modalities, such as clofazimine, hydroxychloroquine, or sulfasalazine, were alternatives to glucocorticoid regimens, thus avoiding the long-term side effects of corticosteroids. Surgical intervention should only be performed in severely disfiguring cases. CONCLUSIONS: The management of cheilitis granulomatosa remains a challenge. As this study revealed a low chance of developing Crohn's disease, it does not seem justified to inform patients with cheilitis granulomatosa of the possibility that they might develop Crohn's disease. Patients with a negative history of gastrointestinal complaints should not be exposed to routine investigations of the gastrointestinal tract.

Adolescent↗