Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CERVIX NEOPLASMS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1975

[Experiences and results in the radiotherapy of 1013 patients with uterine cervix neoplasms].

The cases of 1013 patients with carcinoma of the cervix are reviewed, who underwent primary radiation treatment in the time from 1951 through 1968. This patient-population is analyzed. The radiation method is described. Out of 1013 women, 496 (49%) survived without recurrences for five years: 80.8% had Stage I disease; 69.7%, Stage II; 38.8%, Stage III; 7.7%, Stage IV. The five-year survival amounted to 53.0%, the relative effectiveness to 61.5 per cent. Complications, side-effects and secondary diseases are reported, as well as the observations of recurrences found by us.

Cobalt Radioisotopes↗
PubMed1986

[Complications of the treatment of cervix neoplasms by radiotherapy].

Of 939 patients treated by radiotherapy for carcinoma of the cervix at the hôpital Notre-Dame in Montreal, between 1979 and 1981, 275 (29.3%) had digestive, urologic, gynecologic, vascular, osseous and cutaneous complications. Surgery was necessary to treat 73 complications in 55 patients (5.9%): 42 digestive (25 occlusions, 13 fistulas and 4 perforations); 22 urologic (16 occlusions, 5 fistulas, 1 hemorrhage); 6 gynecologic (3 hemorrhage and 3 uterine necrosis); 1 cutaneous, 1 vascular and 1 osseous necrosis. No direct correlation was found between the incidence of the complications and certain predisposing factors such as the type of radiotherapy, patients' age, stage of the disease and gynecologic surgery before radiotherapy. However, there was a strong correlation between the incidence of complications and the dose of radiotherapy and the need for gynecologic surgery after radiotherapy. High morbidity was observed in the 55 patients treated surgically: they had to undergo a mean of 2.36 operations each, 2.98 general anesthetics, 1.81 hospitalizations (mean duration 75.7 days); 21 had one or more definitive stomas. The death rate was 5.45%. Surgical treatment was individualized. Limited resections were performed for occlusions, fistulas and perforations whenever it was technically feasible to treat digestive and urologic complications. A bypass procedure was used when resection would have been too extensive or dangerous. The majority of rectal lesions were treated by colostomy and a Hartmann procedure.

Adolescent↗
PubMed1979

[Does cancer preventive care on the cervix need to be reformed? Gynecological preventive care and early diagnosis--current knowledge on cervix neoplasms].

A comparative study shows high incidence of preclinical cancerous lesions of the uterine cervix in women under thirty years of age. The rate of positive cytology in this age group was the same as in the group of women over thirty (0.3 per cent each). The histological findings revealed intraepithelial lesions like dysplasia and carcinoma in situ in the younger group compared to more advanced lesions like microinvasive cancer in the higher-aged group. The use of colposcopy rendered optical evidence--predominantly in the younger group--of lesions which under long-term observation preceded positive cytology for years as well as the consequent histological proof of dysplasia and preclinical carcinoma. As a result of the given and discussed clinical data in both compared age groups the value of colposcopy is stressed in improving the quality of detection of preclinical neoplasia in the uterine cervix and the necessity of cancer-screening in younger-aged women is emphasized.

Adult↗
PubMed1994

[Activity of cathepsin B and D in blood serum of women with uterine cervix neoplasms].

The activity of cathepsins B and D were determined in the serum in 98 patients with carcinoma of the cervix uteri and in 25 women with dysplasia of the cervix uteri. The clinical value of the examined enzymes was performed. The results show that the mean serum activity of cathepsins increase with progression of neoplastic disease. The elevation of at least one of two studied lysosomal hydrolases were estimated in 68 patients (69.5%) with carcinoma of the cervix uteri.

Adult↗