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At least 19 recordsLinked to original sources

From Baltimore to Boston: the establishment of the first dental schools in Boston.

The advent of dentistry in America was in Boston in 1630, according to Weinberger. Yet it was not until 1867-68, one hundred and twenty-five years ago, that the first two dental schools appeared in Boston, essentially simultaneously: Harvard Dental School and the Boston Dental College, the forerunner of Tufts University School of Dental Medicine. This paper describes the early and rich heritage of dentistry in Boston and records the tumultuous birth of these two dental schools, each of which has endured and has remained true to its initial mission.

Baltimore↗

Boston University's biosciences education program for Boston-area students.

The authors describe the CityLab program, which has the goal of providing equal educational opportunities in biotechnology and medical sciences for all students in the greater Boston area in grades seven through 12, particularly students from groups traditionally underrepresented in science. Since 1992, more than 16,000 students and 1,200 teachers have participated in the program's activities, which focus on giving students meaningful laboratory experiences in the biosciences (either at Boston University of by means of a traveling laboratory in a bus). Students develop confidence in their ability to apply molecular biology and biotechnology concepts and skills to scientific problems and learn that they can pursue careers in the biosciences. The authors describe the CityLab program, its inquiry-based teaching methods, its effects, and its potential to increase students' interest in biomedical studies and careers.

Boston↗

Psychotropic drug use in the Boston area. A report from the Boston Collaborative Drug Surveillance Program.

During 1972, adults admitted to general medical and surgical wards in Boston area hospitals were interviewed to determine their use of prescribed psychotropic drugs prior to hospitalization. Patients hospitalized for psychiatric disorders or psychogenic ("functional") disease were excluded. Patients who had taken prescribed drugs that could not be identified were considered nonusers. Of the total sample, 20% gave a histroy of psychotropic drug use. Antianxiety drugs were taken by 15% of the patients and accounted for two thirds of total psychotropic drug use. Hypnotics were taken by another 4% of the sample. Slightly over half of antianxiety and hypnotic drug use was for a year or more. Use was more frequent in patients with potentially chronic medical disorders. The findings, in general, are consistent with other studies employing other methods to investigate the use of psychotropic drugs. Simple studies of use, however, do not provide a sole or adequate definition of treatment option, need, or efficacy.

Adult↗

Oral contraceptives and hepatitis. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center.

History of oral-contraceptive use was compared between 68 women with a hospital-discharge diagnosis of acute hepatitis and 1142 women who had been admitted for other reasons to the same hospitals during the same period. The risk of admission to hospital for hepatitis for users of oral contraceptives was estimated to be 3-3 times that for non-users (95% confidence interval, 1-8--6-3). This overall association was almost entirely attributable to a strong association among women under 25 years of age. Among users of oral contraceptives, duration of use tended to be shorter for hepatitis patients than for controls.

Acute Disease↗

Relation between smoking and age of natural menopause. Report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center.

The relation of cigarette smoking to natural menopause has been evaluated in two independent sets of data. In both, at each age from 44 to 53 years, more current smokers were post-menopausal compared to "never" smokers. In the first set of data the age-standardised proportions of women who were postmenopausal were 35, 36, 43, and 49%, respectively, for never smokers, ex-smokers, and current smokers of 1/2 and greater than or equal to 1 pack per day. The corresponding proportions for the second set were 53, 59, 60 and 65%.

Adult↗

Use of pneumococcal vaccine for prevention of recurrent acute otitis media in infants in Boston. The Greater Boston Collaborative Otitis Media Study Group.

The efficacy of pneumococcal polysaccharide vaccine for children suffering from recurrent acute otitis media (AOM) was determined by administration, in a randomized double-blind fashion, of one of two polyvalent vaccines to 124 children aged five to 21 months. The octavalent vaccine contained serotypes commonly associated with AOM: 1, 3, 6A, 7F, 14, 18C, 19F, and 23F. The heptavalent control contained serotypes not commonly associated with AOM: 2, 4, 5, 8, 9N, 12F, and 24F. Recipients of the octavalent vaccine experienced significantly (P less than 0.05) less AOM due to serotyes contained in the octavalent vaccine than did children who received the control vaccine. Although the recipients of octavalent vaccine suffered less from AOM due to types in that vaccine than did controls, their clinical experience with AOM was not different. Both groups of children were equally likely to experience at least one episode of AOM after vaccination (70% for octavalent vaccine and 78% for heptavalent vaccine). The mean numbers of episodes of AOM after vaccination also were similar (2.1 for octavalent vaccine and 2.3 for heptavalent vaccine). Similarly, the period of effusion in the middle ear after pneumococcal AOM was identical for both groups. Although immunization with pneumococcal vaccine appeared to reduce the number of episodes of AOM due to serotypes contained in octavalent vaccine, the clinical experience of the children was not favorably affected by this vaccine.

Acute Disease↗