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At least 19 recordsLinked to original sources
PubMedDate not supplied

Lead levels in blood bank blood.

Although blood bank blood is usually screened for dangerous pathogens, the presence of toxic metals in blood has received little attention. Population blood lead levels have been declining in the United States, but occasional high outliers in blood lead concentration can be found--even when mean levels of blood lead are low. We sampled 999 consecutive blood bank bags from the King/Drew Medical Center, used between December 1999 and February 2000. The geometric mean blood lead level was 1.0 microg/dl (0.048 micromol/l), but 0.5% of the samples had lead levels that exceeded 10 microg/dl, and 2 samples had lead levels that exceeded 30 microg/dl. The 2 samples with the highest lead levels could have presented an additional risk to infants if they were used for blood replacement. Therefore, even in countries with generally low population blood lead levels, blood bank blood should be screened for lead concentration prior to use with infants.

Blood Banks↗
PubMed1975

Pseudocholinesterase activity of human whole blood, bank blood, and blood protein solutions.

Pseudocholinesterase (E.C. 3.1.1.8) activity was measured in plasma of whole blood, bank blood, and several commercially available blood protein solutions by means of a colorimetric assay technique at 25 degrees C, pH 7.7, and with butyrylthiocholine as substrate (Merckotest-R No. 3337). Activity of whole blood was 5.79 plus or minus 0.20 U x ml-1, of bank blood 4.53 plus or minus 0.27 U x ml-1, and of two human serum solutions (Biseko-R, Seretin-R) 3.05 plus or minus 0.13 and 3.04 plus or minus 0.22 U x ml-1, respectively (mean plus or minus S.E.M.). The other blood protein solutions contained no clinically significant esterase activity. Since transfusion of blood plasma has been suggested for treatment of cholinesterase deficiency and postoperative suxamethonium-induced muscle paralysis, an in-vitro attempt was carried out to correlate the amount of plasma necessary and the rise of pseudocholinesterase activity in the recipient's blood: A large amount of blood has to be transfused to yield a comparatively small increase in esterase activity. Thus, considering the potential hazards of blood transfusion, this treatment does not seem to be advisable.

Anesthesia, General↗
PubMedDate not supplied

Military blood banking: blood transfusion aboard a Naval hospital ship receiving multiple casualties in a combat zone, a controlled medical environment.

The materials, methods, and policies used in the Blood Transfusion Service aboard the USS Sanctuary (AH-17) during military operations off South Vietnam to transfuse multiple casualties are outlined. Materials and methods common to any blood bank were used with some modification to meet specific requirements. During the period 10 April 1967 to 1 May 1971, approximately 32,000 units of blood were recieved, and over 2,890 severely injured patients were transfused. The policies and techniques used enabled efficient and safe management of blood transfusion for these patients. These methods should be applicable in solving some of the problems which arises as a result of combat operations and civil disasters. A controlled medical environment is described.

Adolescent↗
PubMed1982

Recruitment of participants from blood banks.

Blood banks represent a recruitment source with relatively high volumes of initial contacts and entries, a low ratio of entries to initial contacts and a relatively low effort level requirement for the recruitment team. For the CPPT, blood banks were used to some extent by all centers; they provided 26% of initial contacts and 15% of first protocol visits and entries. Probably the most critical determinant of a successful collaboration was the early negotiation with the blood bank director. Several features seemed to characterize successful LRC/blood bank collaborations: Blood banks that were willing to release names and addresses to the LRC, provided staff support, did not request monetary reimbursement, and agreed, sometimes enthusiastically, to participate in joint media campaigns tended to produce the most referrals. Blood banks are well adapted to identify healthy, asymptomatic men with an abnormal laboratory finding identifiable by a blood test.

Adult↗
PubMed1994

Quality systems and total process control in blood banking.

Blood banking has dramatically changed in the past few years. Is the old business hierarchy and medical model for management still workable? How do we want to organize our work today for success in the future? Implementation of quality systems may seem overwhelmingly complex at this time to many blood banking establishments. However, by methodically adhering to the requirements of organization development described in this review, blood centers can achieve goals of quality improvement and TPC. The FDA and the pharmaceuticals and medical device industries have set the direction and provided guidance to blood establishments. The AABB, American Society for Quality Control, the American Society for Training and Development, and numerous other professional organizations can contribute information and materials. The FDA's document on quality assurance and the CFR are the basic texts guiding the approach presented in this paper. The organization's structure and processes may need to be reengineered to meet the requirements of a culture based on quality and process control.

Blood Banks↗
PubMed1998

Fibrin sealant: an evaluation of methods of production and the role of the blood bank.

Blood banks can prepare fibrin sealant by several methods. Allogeneic components allow for banking of the fibrinogen concentrate for immediate use. Autologous components eliminate the risk of transfusion-transmitted disease to the recipient, but not necessarily to the preparer. Ethanol and ammonium sulfate precipitation of fibrinogen concentrate allow use of autologous blood and fast preparation (less than 90 minutes). Cryoprecipitation from liquid plasma is adequate, conserving fresh frozen plasma. Cryoprecipitation by the "freeze-thaw" method has been reported to have the highest fibrinogen yield (7840 mg/dL +/- 1800 mg/dL), whereas ammonium sulfate precipitation has been reported to have the highest bonding strength (41 g/cm2 10 minutes after thrombin addition). Cost, storage, preparation time, and transfusion-transmitted disease all play a role in choice of method.

Animals↗