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Local cost sharing in Bamako Initiative systems in Benin and Guinea: assuring the financial viability of primary health care.

The fourth in a series of five, this article presents and analyses data on cost recovery and community cost-sharing, two key aspects of the Bamako Initiative which have been implemented in Benin and Guinea since 1986. The data come from approximately 400 health centres and result from the six-monthly monitoring sessions conducted from 1989 to 1993. Community involvement in the financing of local operating costs in the two national scale programmes is also described. In Benin and Guinea, a user fee system generates the community financed revenue with the aim of covering local operating costs including drugs. Health worker salaries remain the responsibility of the government and donor funding covers vaccine and investment costs. Village health committees manage and control resources and revenue. The community is also involved in decision making, strategy definition and quality control. In Benin in 1993, community financing revenue amounted to about US$0.6 per capita per year and generally covered all local recurrent non salary costs except vaccines and left a surplus. Although total costs and revenues were slightly lower in Guinea for the same period, over-all user fee revenue (around US$0.3 per capita per year) covered local recurrent costs (not including salaries or vaccines). A comparison of costs and revenue between regions and individual health centres revealed important differences in cost recovery ratios. In Benin, some centres recovered more than twice the local costs targeted for community financing. Twenty-five per cent of centres in Guinea did not manage to cover their designated local recurrent costs. The longitudinal analysis showed that the level of cost recovery remained stable over time even as preventive care (and especially EPI) coverage rose significantly. To better understand the most important characteristics affecting cost recovery levels, best performing health centres in terms of cost-recovery levels in 1993 were compared to worst performing centres. This analysis showed that the size of the target population of the health centre is a key determinant of cost-recovery in both countries. In addition, in Guinea the utilization of curative care linked to geographical access and in Benin the average revenue per case linked to the number of deliveries proved to be additional factors of importance. In best performing centres, financial viability improved over time in both countries between 1990 and 1993. Finally, the implications of these conclusions for the planning of health centre revitalization in West Africa are discussed.

Benin↗

The problems of management of gestational trophoblastic neoplasms at the University of Benin Teaching Hospital, Benin City, Nigeria.

Analysis of 31 cases of gestational trophoblastic neoplasms at the University of Benin Teaching Hospital, Benin City, over a 7 1/2 year period (1/1/75 to 6/30/82) was carried out. The incidence of this disease was 1:656 deliveries. Although it was more prevalent in grandmultipara, it occurred in all parities and ages. The main clinical features were secondary amenorrhea, vaginal bleeding, uterine enlargement, and vaginal secondaries. The most common gestational antecedent event of gestational trophoblastic disease was a normal pregnancy. This was believed to have contributed to the high overall mortality of 35.5%. Numerous shortcomings during the management of these cases (inadequate laboratory facilities, shortage of reagents, shortage of drugs) were highlighted.

Adult↗

Broken paediatric appointments at the University of Benin Teaching Hospital, Benin City.

Appointment system was introduced to the University of Benin Teaching Hospital at the initial stage of the Hospital development. This is a new experience to the local community which is largely illiterate. The appointment breaking was low contrary to expectation. Indifference or negligence accounted for a high percentage of defaulting. The system was deemed to be good by 66.4 per cent of the defaulters interviewed only 1.2 per cent felt that it was bad. Efforts by the health visiting Sister to visit the defaulters at home and persuade them to attend the clinic reduced the number of broken appointments. The habit of breaking appointments by parents/guardians of children who showed indifference or negligence were more difficult to remedy. For a referral system to be effective in a largely illiterate community where referral system is new, knowledge of the reasons for breaking appointments in the community should be known and remedied. Promotion of personalized attention and intensive health education are essential.

Adolescent↗

Affordability, cost-effectiveness and efficiency of primary health care: the Bamako Initiative experience in Benin and Guinea.

Since 1986 two West African countries, Benin and Guinea, have been actively reorganizing their peripheral health systems according to strategies subsequently called the "Bamako Initiative". Two preceding articles described the strategies implemented and the increased effectiveness of primary health care (PHC) witnessed over a period of six years. This article presents an analysis of cost and coverage data from biannual monitoring sessions between 1988 and 1993 in approximately 200 health centres in Benin and 214 in Guinea. In order to assess affordability, the total and per capita recurrent costs for operational health centres are analysed and then compared. The cost analysis reveals a mean total cost per health centre per year of slightly over US+11,000 in Benin and nearly US+9,000 in Guinea. The median cost per capita per year is approximately US+1.0 in Benin and between US+0.60 and US+0.80 in Guinea. Comparisons of these costs between regions, health centres and over time (as coverage levels evolved) show very little variation in either country. Cost-effectiveness is estimated by allocating these costs to immunization, antenatal and curative care and comparing them to the coverage achieved with these interventions. First, the cost-effectiveness of the Bamako Initiative (BI) system as a whole is analysed. The cost per fully vaccinated child is calculated at US+10.9 in Benin and US+8.8 in Guinea. The cost per woman receiving at least three antenatal visits is US+7 in Benin and US+4.7 in Guinea. For curative care, cost per full treatment is US+1.6 in Benin and half this amount in Guinea. Cost-effectiveness is variable between regions, health centres reveals that these differences in cost-effectiveness are mainly caused by the coverage levels achieved, since total costs are relatively stable. Finally the efficiency of drug management and prescriptions as well as of outreach for the expanded programme of immunizations (EPI) is estimated by relating specific drug and outreach activities costs to the number of beneficiaries. The average cost of drugs per treatment is around US+0.5 in Benin and around US+0.3 in Guinea. Cost analysis of outreach activities undertaken for EPI in Guinea revealed a similar average cost per child completely vaccinated for health centres with different intensities of outreach (approximately US+10) and an additional cost per child vaccinated attributable to outreach of US+1-2.

Benin↗

The Bamako Initiative in Benin and Guinea: improving the effectiveness of primary health care.

The objective of the health system revitalization undergone in Benin and Guinea since 1986 is to improve the effectiveness of primary health care at the periphery. Second in a series of five, this article presents the results of an analysis of data from the health centres involved in the Bamako Initiative in Benin and Guinea since 1988. Data for the expanded programme of immunization, antenatal care and curative care, form the core of the analysis which confirms the improved effectiveness of primary health care at the peripheral level over a period of six years. The last available national data show a DPT3 immunization coverage of 80% in 1996 in Benin and 73% in 1995 in Guinea. In the Bamako Initiative health centres included in our analysis, the average immunization coverage, as measured by the adequate coverage indicator, increased from 19% to 58% in Benin and from less than 5% to 63% in Guinea between 1989 to 1993. Average antenatal care coverage has increased from 5% in Benin and 3% in Guinea to 43% in Benin and 51% Guinea. Utilization of coverage with curative care has increased from less than 0.05 visit per capita per year to 0.34 in Guinea and from 0.09 visit per capita per year to 0.24 in Benin. Further analysis attempts to uncover the reasons which underlie the different levels of effectiveness obtained in individual health centres. Monitoring and microplanning through a problem-solving approach permit a dynamic process of adaptation of strategies leading to a step by step increase of coverage over time. However, the geographical location of centres represents a constraint in that certain districts in both countries face accessibility problems. Outreach activities are shown to play an especially positive role in Guinea, in improving both immunization and antenatal care coverage.

Benin↗

[Resistance of malaria vectors to pyrethrins used for impregnating mosquito nets in Benin, West Africa].

Impregnated bednets can be considered a major tool for reducing Anopheles bites, malaria morbidity and overall mortality. The resistance of Anopheles gambiae to pyrethroids used to impregnate bednets and curtains has already been noted in the urban area of Cotonou in Benin (18, 21). In this study, we wished to find out if the resistance observed in Cotonou is localized only in this town or is already extensive throughout Benin. In this case, such resistance would be a handicap to the promotion of impregnated bednets in Benin. The study was carried out in 15 localities throughout the different ecological zones of Benin. The study has also taken into account environmental factors favouring the emergence of resistance. We did susceptibility tests with WHO test kits for adult mosquitoes using impregnated papers. The papers were impregnated with permethrin 0.25%, deltamethrin 0.025% and lambdacyhalothrin 0.1%. We also tested DDT 4% to find out if there was a cross resistance between DDT and the pyrethroids. Two mosquito species were tested: An. gambiae and An melas. In northern Benin, where farmers use insecticides against cotton pests, vectors are susceptible to deltamethrin and lambdacyhalothrin and resistant to permethrin. In the south, An. gambiae is resistant to deltamethrin and permethrin. This resistance is high in the urban zone of Cotonou, in the coastal and lagoon areas and at Kraké, a frontier viliage with Nigeria. The resistance observed in southern Benin is confirmed by the lengthening of the knock-down time of mosquitoes which were exposed for 1 hour to insecticide in impregnated WHO test tubes, and by a reduction of permethrin and deltamethrin remanence effect.

Animals↗

[Memisa and the development of a health care system in Benin].

The organization Memisa Medicus Mundi puts the emphasis of its activities in third world countries such as Benin on the structural development of a solid health care system. This policy is being implemented through close cooperation with local partners. This strategy allows for interventions which do not upset the existing social relationships and which do not have a negative influence on the performance of health care institutions. The general health of the Benin population is poor: life expectation at birth is 47 years and 24% of children under the age of 5 suffer from undernutrition. With financial and technical support of Memisa, three hospitals have been set up in North Benin which later on were turned over to the Benin physicians. In addition, a system of medical insurance was started up, based on the traditional forms of mutual solidarity. Progress may be accelerated by coordinating the aid of non-governmental organizations in Benin; to this purpose, Memisa has aided in founding AMCES (Association des Oeuvres Médicales Privées Confessionnelles et Sociales--Private, Confessional and Social Health Care Association), a union that serves as a discussion partner for the government and helps supplying the country with medicaments.

Benin↗

HIV seroprevalence in women of childbearing age in Benin City, Nigeria.

HIV seroprevalence was still low in some parts of Nigeria from 1989 to 1991, and only limited reports were available on seroprevalence in childbearing women. In order to assess HIV seroprevalence in pregnant women in Benin City and Bendel State, two sampling methods, unlinked anonymous testing and voluntary testing, were employed. Data obtained from testing 358 sera from pregnant women attending antenatal clinics and cord blood from labour wards in Benin City were compared with data obtained from testing 833 pregnant women at four sentinel surveillance sites in Bendel State. The samples were all analysed by ELISA technique at the University Teaching Hospital, Benin City. Repeatedly reactive samples were confirmed by Western blot. The seroprevalence of HIV-1 in Benin City and in Bendel State was 0.28 percent and 0.36 percent, respectively. At this point in time, intensive health education campaigns targeted at the general population are necessary.

Adolescent↗

Trypanosomiasis in different breeds of cattle from Benin.

Blood of different breeds of cattle, namely Lagune from the Atlantic province, Borgou and Borgou x Zebu from the Borgou province, and Somba and Zebu from the Atacora province of Benin, were examined for trypanosome infection. Thick and thin blood smears for trypanosomes, the card agglutination test (CATT), indirect immunofluorescent antibody test (IFAT) and trypanolytic test for antibodies to trypanosomes were used. Trypanosomes were detected in 19.3% (range 9.8-31.4%) of animals by examination of blood smears; antibodies to trypanosomes were found in 89.8% (range 88.4-100%) of samples by IFAT, 50.6% (range 34-87.5%) by CATT and 3.4% (range 1.1-7.1%) by trypanolytic test. Trypanosoma vivax and Trypanosoma congolense were the main species in Benin with a low number of Trypanosoma brucei. Zebu had lower infection rates than trypanotolerant breeds of Benin. The infection rates of various trypanotolerant breeds were not significantly different.

Agglutination Tests↗

Seroepidemiology of human T-cell lymphotropic virus type I/II in Benin (West Africa).

In 1988-1989, a national survey was conducted in Benin to determine the distribution of HTLV-I infection in a representative sample of adult individuals. This study comprised 2625 healthy subjects recruited in the six provinces of Benin and 1300 blood donors from Cotonou and from the other five provinces. Sera were screened for HTLV-I antibody by both immunofluorescence (IF) and enzyme immunoassay (EIA). Sera positive or doubtful by at least one technique were further analyzed by Western blot and radioimmunoprecipitation assay (RIPA) when indeterminate. Samples were considered as positive if they reacted with two gene products. No blood donor was positive. Over the 2625 subjects, 39 (1.5%) were positive. We observed a statistical difference between male and female (1%, 2%, p less than 0.05). A difference was also observed according to the areas studied: the HTLV-I antibody rate increased from coastal (0.3%) to northern (5.4%) provinces. HTLV-I seroprevalence increased significantly with age. This survey shows that HTLV-I infection exists in Benin but varies according to regions.

Adult↗

Determination of discretionary salt intake in rural Guatemala and Benin to determine the iodine fortification of salt required to control iodine deficiency disorders: studies using lithium-labeled salt.

The use of discretionary salt, which is salt added during cooking and at the table, as a suitable vehicle for iodine intake was assessed by measuring salt consumption using the lithium-marker technique in rural areas of Guatemala and Benin. In both countries, we studied boys aged 6-12 y and their mothers. Subjects used lithium-labeled salt after all unlabeled salt was removed from their households. In Guatemala, 24-h urine samples for 9 mother-son pairs were collected at baseline and on days 7, 8, and 9 during the use of lithium-labeled salt. Total maternal salt intake averaged 5.2 +/- 1.7 g/d (mean +/- SD), of which 77 +/- 24% came from discretionary sources, whereas Guatemalan boys consumed 1.8 +/- 0.6 g salt/d, of which 72 +/- 12% came from discretionary sources. In Benin, urine collection from 13 mother-son pairs took place at baseline and on days 5 and 7. Beninese mothers had a total salt intake of 9.0 +/- 2.9 g/d and their sons had an intake of 5.7 +/- 2.8 g/d; discretionary salt contributed 52 +/- 14% and 50 +/- 13%, respectively, of total salt consumed. Therefore, fortification of household salt appears to be an appropriate method of controlling iodine deficiency in both countries, although fortification of other salt sources could be considered in Benin.

Adult↗

Plasmodium falciparum sporozoite loads in Anopheles gambiae s.l. across agro-ecological zones of Benin: a cross-sectional field study.

BACKGROUND: Malaria transmission depends critically on the vectorial competence of Anopheles mosquitoes, which is partly reflected by the quantity of infectious Plasmodium falciparum forms harboured in the salivary glands. Whether agro-ecological heterogeneity and vector species identity modulate this parasite burden remains poorly characterized in Benin. METHODS: Anopheles gambiae s.l. were collected by Human Landing Catch across 12 localities spanning 7 agro-ecological zones in Benin during August-October 2022. Species were identified by SINE-PCR. P. falciparum infection was assessed by circumsporozoite protein (CSP) ELISA, and sporozoite load was quantified in positive head-thorax preparations by real-time PCR targeting the plasmepsin gene (NZYTech kit, ref. MD 02411). Statistical comparisons across agro-ecological zones (within each species) used the Kruskal-Wallis test, and the two-species comparison used the Mann-Whitney U test, in R v4.4.1. RESULTS: A total of 1,355 individuals were molecularly analyzed for species identification. Of 3,021 mosquitoes collected, these 1,355 yielded 858 An. coluzzii (63.32%), 489 An. gambiae (36.09%), and 8 An. arabiensis (0.59%). The overall sporozoite index was 5.98% (95% CI 4.8-7.4%), ranging from 0% in Cotonou and Parakou to 16.19% in Boukoumb&#xe9;. No significant inter-zonal variation in sporozoite load was detected in either An. coluzzii (Kruskal-Wallis: H&#x2009;=&#x2009;5.79, df&#x2009;=&#x2009;3, p&#x2009;=&#x2009;0.122) or An. gambiae (H&#x2009;=&#x2009;3.25, df&#x2009;=&#x2009;2, p&#x2009;=&#x2009;0.197). However, An. coluzzii carried a significantly higher sporozoite burden than An. gambiae (Mann-Whitney U&#x2009;=&#x2009;381, p&#x2009;<&#x2009;0.001). CONCLUSIONS: Broad agro-ecological zone categories were not associated with detectable differences in individual P. falciparum sporozoite load in the principal malaria vectors of Benin. Anopheles coluzzii carried a significantly higher sporozoite burden than An. gambiae, indicating species-level differences in parasite permissiveness that merit further investigation.

Anopheles coluzzii↗

[Blindness in Benin].

A population-based survey of the prevalence and cause of blindness and poor vision was conducted in the Republic of Benin in 1990 using a stratified cluster random sampling procedure. The survey was designed and implemented through the collaboration of the Ministry of Health of the Republic of Benin and the Programme for the Prevention of Blindness of the World Health Organization (WHO/PBL). Survey data were analyzed at the International Centre for Eye Health, Institute of Ophthalmology, University of London, United Kingdom. In accordance with the procedures recommended by WHO/PBL, 7272 individuals were recruited and 7047 were examined. The survey achieved excellent coverage in all locations with an overall coverage of 96.9%. The prevalence of blindness (visual acuity less than 3/60 in the better eye) was 0.6% (CI95% = 0.4%-0.9%). The prevalence of poor vision (best vision less than 6/60 but not blind in the better eye) was estimated at 2.6% (CI95% = 2.1%-3.1%). The major causes of blindness were age-related cataract and glaucoma (54% and 15% respectively of blind people recruited). The major cause of poor vision were cataract, refractive errors, and macular disorders (64%, 9.6%, and 9.0% respectively of people recruited with poor vision. The survey results indicate that there is an urgent need for basic eye care services. Cataract has been designated as a priority target in the recently designed National Blindness Prevention Programme now being implemented in the Republic of Benin. With proper management of this problem, the current prevalence of blindness and poor vision could be reduced by at least 45%. At the end of this cluster study, the design effect (D = 1.56) and rate of homogeneity (ROH = 0.002) were computed for an average number of 250 people per cluster.

Adolescent↗

[Outbreak of foot-and-mouth disease in Northern Benin during the 1990-1991 dry season].

An outbreak of foot-and-mouth disease damaged the North-Benin during the 1990-1991 dry season (November to May). Coming from outside the Benin, it spread out very quickly in the country essentially because of trans-humant herds. No measures have been taken to limit this sickness which is endemic and which regularly exhibits outbreaks in Benin. Antibodies to types A, O and SAT2 of the foot-and-mouth disease virus were detected in the sera during this outbreak.

Animals↗

[Trends in the HIV/AIDS epidemic in Benin (1990-1993].

Since 1990 within the framework of a National Program against AIDS, surveillance in the Republic of Benin has relied on disease-control centers established in 20 selected locations. Seropositivity for HIV is always established by Western-blotting and diagnosis of AIDS is based on BANGUI/WHO clinical criteria and positive serologic tests. On June 30, 1993, the cumulative number of AIDS cases reported to the WHO was 12/100000 inhabitants of Benin. The sex-ratio was 2 to 1 and 77.4% of cases occurred in the 20 to 49 year age range. Heterosexual transmission accounted for 75.8% of cases and mother-to-child transmission for 6.4%. Overall the cumulative number of AIDS cases doubled each year from 1990 to 1992. The prevalence of HIV antibodies in target groups has been steady: less than 1% of blood donors and urban or rural women undergoing prenatal examinations. The prevalence of HIV antibodies has risen significantly every year among patients with tuberculosis and people consulting for sexually transmitted diseases. These findings corroborate the notion that the incidence of positive serologic tests for HIV is low in Benin: less than 1% of the adult population.

Adolescent↗

[Birth intervals and birth of low weight infants in Benin].

Low birthweight is a public health problem in Benin but its etiology remains unclear. Studies in industrial countries suggest several risk factors including the interval between pregnancies or child spacing. The purpose of this cohort study was to assess the relationship between pregnancy interval and low birthweight in Benin. Data were collected from a total of 2,862 multiparous pregnant women randomly recruited in 1991 at the time of their first prenatal care visit to maternity units in Cotonou, Benin. Sociodemographic information and obstetrical history were obtained by interviewing the mother and reviewing delivery records. About 15% of the women recruited delivered low birthweight children. The relative risks of preterm birthweight and intrauterine growth retardation was calculated in function of three pregnancy intervals: less than 12 months, 12 to 23 months, and 24 to 34 months. It was 1.31 (1.00-1.75), 1.00 (0.70-1.02)) and 0.77 (0.60-0.87) respectively for preterm birthweight and 1.27 (1.03-1.64), 1.17 (0.79-1.39) and 0.79 5 (0.57-0.87) respectively for intrauterine growth retardation. Logistic regression analysis taking into account sociodemographic factors and previous obstetrical history did not show a significant correlation between pregnancy interval and preterm low birthweight or between pregnancy interval and intrauterine growth retardation. Maternal nutritional status, maternal age, number of previous births, and education level were correlated with low birthweight.

Adult↗