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At least 19 recordsLinked to original sources

[Platelet-rich plasma (platelet gel) in secondary alveoloplasty in cleft patients].

INTRODUCTION: The use of Platelet-rich plasma (platelet gel--PRP--) was introduced in the oral and maxilofacial surgery 10 years ago. Its good results are due to the quickly generation of new bone and the acceleration of the period of surgical scar formation. Its employment in the alveolar reconstruction of the cleft patient is not still consistent and the works published in the literature are infrequent. The objective of this preliminary study is presenting our experience with the use of PRP in the reconstruction of the alveolar congenital defects of cleft patients. PATIENTS AND METHODS: Between July 2002 and January 2004 were operated 14 patients with congenital alveolar cleft carrying out an standard secondary alveoloplasty. In 12 cases was employed cancellous bone of iliac crest and in two cases the donor area was tibial. The laboratory of Hematology of our Hospital prepared the plasma gel rich in platelets by means of a double centrifuge of autologous serum of the patient. After adding calcium a rich gel in platelets in approximate quantities of 1-2 ml was obtained. In this preliminary report we have studied the aspect of the surgical injury the 3er postoperative day, and the first and second weeks after intervention. These results were compared carried out previously with the Standard alveoloplasty without use of the PRP. Likewise we evaluated the bony density by means of intraoral Rx at 3 and 6 months postoperative. RESULTS: The injury of the alveoloplasty healed more quickly in the patients in which plasma enriched gel was employed. The patients referred less pain and edema in the first days of the postoperative period. The alveolar bony regeneration was faster to the 3 months, though the result was similar in the intraoral Rx to the 6 months. The necessary quantities of cancellous bone were smaller in all cases in which the plasma enriched gel was used (30% less). CONCLUSIONS: The use of Platelet-rich plasma (PRP) is a valid protocol for the reconstruction in patients with congenital alveolar clefts. Its low price and morbidity do it recommendable for its employment in cleft patients.

Alveolar Process↗

[Evaluation of restorative alveoloplasty].

The method of restorative alveoloplasty is often marred by complications which may cause the failure of this laborious intervention. For this reason, this procedure should remain confined to single cases. It is imperative to search for new ways to reconstruct the bony denture support.

Alveoloplasty↗

[Flap techniques in secondary alveoloplasty: a comparison between two types of flap].

INTRODUCTION: The aim of this study was to compare two surgical soft tissue coverage techniques of secondary alveolar grafts in cleft lip and palate patients: the gingival mucoperiostal slidind flap and the mucosal rotation flap. MATERIAL AND METHOD: Fifty-two secondary alveolar bone grafts were retrospectively included in the study. Four clinical parameters were evaluated: post-operative dehiscence, oro-nasal fistula relapse, canine eruption through the graft and postoperative secondary periodontal procedures. RESULTS: Gingival mucoperiostal flaps had less postoperative dehiscence, more fistula relapse and needed less secondary periodontal procedures. DISCUSSION: Based on this study and on literature data, gingival mucoperiostal flap provides better quality of soft tissue coverage. Flap design doesn't influence canine eruption. Bone graft complications are increased with poor oral hygiene, if canine eruption occurred before surgery and in older patients.

Adolescent↗

Articulatory behavior pre and post full-mouth tooth extraction and alveoloplasty: a cinefluorographic study.

High speed cinefluorography was used to track articulatory movements preceding and following full-mouth tooth extraction and alveolplasty in two subjects. Films also were made of a control subject on two separate days. The purpose of the study was to determine the effects of dramatically altering the structural dimensions of the oral cavity on the kinematic parameters of speech. The results showed that the experimental subjects performed differently pre and postoperatively though the changes were in different directions for the two subjects. Differences in both means and variabilities of kinematic parameters were larger between days for the experimental (operated) subjects than for the control subject. The results for the control subject also showed significant differences in the mean values of kinematic variables between days though these day-to-day differences could not account for the effects found pre- and postoperatively. The results of the kinematic analysis, particularly the finding that transition time was most stable over the experimental conditions for the operated subjects, are used to speculate about the coordination of normal speech.

Alveoloplasty↗

Indications on suitable scaffold as carrier of stem cells in the alveoloplasty of cleft palate.

Autologous iliac crest bone is used to close the residual alveolar bone defect in cleft palate patients during late mixed dentition. Surgery involves physical and anaesthesiologic risks, long-time hospitalization, high costs and not always good results (15% failure rate). Alternatives to iliac crest bone grafting are going to be evaluated: synthetic, xenograft and allograft matrices combined with platelet-rich plasma or recombined bone morphogenic proteins for osteoinductivity are commercially available. These alternatives have not yet been determined to be equivalent to the previous treatment. A new field of research is represented by stem cells, which have been also used to regenerate ischaemic cardiac tissue after heart attack, to treat hypophosphatasia and osteoporosis. Our aim was to use osteoblasts from stem cells to close the residual palate cleft in association with a suitable carrier. Stem cells are expanded in the Aastrom bioreactor, differentiated into osteoblasts and positioned in the bone defect by means of a Spongostan scaffold. This scaffold has the best characteristics as commercial availability, low cost, good manageability, absence of allergic reactions or other side effects on patient, biocompatibility, imbibition, radiotransparency, reabsorbability and osteoinductivity. Previous studies encourage Spongostan scaffold application.

Alveoloplasty↗