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At least 19 recordsLinked to original sources
PubMed1991

Pathogenesis of intraabdominal abscess formation: abscess-potentiating agents and inhibition of complement-dependent opsonization of abscess-inducing bacteria.

Bacteroides fragilis and Escherichia coli are synergistic in the production of intraabdominal abscesses. However, these bacteria initiate abscess formation only when inoculated with an agent such as autoclaved colonic contents (ACC) or bran (a fiber analogue). The mechanism of action of the abscess-potentiating agent was studied. Opsonins in normal mouse serum were determined for phagocytic killing by murine neutrophils of B. fragilis and E. coli. Opsonization required fixation of complement by the alternative pathway. ACC (0.2 mg/ml) and bran (1.0 mg/ml) inhibited phagocytic killing of Proteus mirabilis in the presence of normal but not immune serum. Assay of the alternative pathway of complement activation indicated that both bacterial components and abscess-potentiating agents in an abscess-inducing mixture activated complement. These findings suggest that abscess-potentiating agents inhibit opsonization and therefore the subsequent phagocytic killing of bacteria in the nonimmune host.

Abscess↗
PubMed1975

[Abscess of the brain (2nd report)--special reference to surgical indication of extracapsular excision of brain abscess (author's transl)].

Brain abscess persists as a serious diagnostic problem and critical therapeutic challenge since pre-antibiotic era. After antibiotic agents has been introduced, abscess of the brain seems to be a surgical curable intracranial suppurative disease, although surgical mortality and morbidity due to brain abscess are still distressingly high. Recently, the incidence of brain abscess are gradually increasing. In this present situation, it is necessary to reevaluate the previous method and surgical results of brain abscess. Even with new surgical techniques and antibiotics, the mortality rate and number of neurological deficits remain high, as previously methods, it is most important how to eliminate these problems. It was undertaken to determine the significant factors affecting the clinical management of patients with this serious problem. The general outlines of our neurosurgical treatment are given, with emphasis on our surgical schedule of brain abscess, especially brain abscess in congenital heart disease. In this paper, a review of the current status of the surgical methods, operative mortality and morbidity, diagnostic methods and the therapy of brain abscess has been discussed.

Adolescent↗
PubMed1991

[A case of Osler-Weber-Rendu disease with brain abscess; the mechanism of the formation of brain abscess and its treatment in Osler-Weber-Rendu disease].

A 54 year-old man, who had a hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease; O-W-R) accompanied by pulmonary arteriovenous fistulas (PAVFs) and congestive heart failure, developed seizure, right hemiparesis and dysphasia. A brain CT scan revealed a cystic lesion with perifocal edema in left frontoparietal lobe. A contrast enhanced CT scan showed a ring-like enhancement. Dynamic CT scans disclosed that the ring in the cortical side was enhanced more thickly than that in the ventricular side. Considering the severity of the cardio-pulmonary condition, and the deep location of the abscess, we performed an echo-guided aspiration and drainage of the abscess under local anesthesia. No bacteria were demonstrated in the culture of the contents of the abscess. After the surgery, the right hemiparesis and dysphasia were much improved and a CT scan showed the marked reduction of the abscess. However, around eight days after the surgery, the patient showed severe pleural effusion due to progressive heart failure and died on the 11th postoperative day. Autopsy disclosed a shrunken brain abscess, multiple cerebral infarction, multiple PAVFs and severe constrictive pericarditis which was regarded as the cause of death in the patient. In this report, we presented the therapeutic advantage of echo-guided surgery for the treatment of brain abscess in a high-risk patient. We also discussed the mechanism of the formation of brain abscess in patients of O-W-R disease by reviewing published cases.

Arteriovenous Fistula↗
PubMed1979

[Surgical management of abscessing mastitis and of retromammary abscesses].

This paper analyses the frequency of abscess-forming mastitis and retromammary abscess in evaluating patients of 11712 births from 1972 to 1978. In 69 cases we found an abscess-forming mastitis and in 6 cases a retromammary abscess. In differential diagnosis there are discussed the clinical symptoms of both diseases. Whereas in the case of intramammary abscess a radial incision with contra-incision and drainage is made, the retromammary abscess indicates a curved incision according of the retromammary abscess are not so frequent but must be taken into consideration in the differential diagnosis of inflammatory diseases of the mamma during puerperium.

Abscess↗
PubMed1977

Computed tomography (CT) in the diagnosis of intracranial abscesses. Brain abscess, subdural empyema, and epidural empyema.

Nine cases of brain abscess, five of subdural empyema, and one of epidural empyema with associated subdural empyema were identified using computed tomography (CT). Smal and multiple abscesses as well as unilateral, bilateral, and parafalcine empyemas were detected. These lesions were demonstrated rapidly and accurately, even in areas that are demonstrated poorly by other diagnostic techniques. No false-negative studies were found in cases of brain abscess or subdural empyema. However, since the appearance of brain abscesses of CT scans is similar to that of neoplastic and vascular lesions, false-positive reports of brain abscess were encountered.

Brain Abscess↗
PubMed1991

Percutaneous drainage of hepatic abscesses: comparison of results in abscesses with and without intrahepatic biliary communication.

Results of percutaneous drainage performed in eight patients with eight liver abscesses with intrahepatic biliary communication and 22 patients with 26 liver abscesses without biliary communication were analyzed to determine whether the presence of an intrahepatic biliary communication affected the outcome of treatment. The clinical features and response to treatment of both groups were compared. The presence or absence of biliary communication was determined by injection of contrast material into the abscess under fluoroscopic guidance either during or several days after initial drainage. Duration of drainage was longer (p less than .05) in patients with communication (range, 7-44 days; mean, 22 days) than in patients without communication (range, 1-33 days; mean, 13 days). Percutaneous drainage was curative in five (63%) and palliative or temporizing in one (13%) of eight patients with communication. It was curative in 15 (68%) and palliative or temporizing in five (23%) of 22 patients without communication (p = .317). Liver abscesses with intrahepatic biliary communication did not require percutaneous transhepatic biliary diversion for cure. Despite longer duration of drainage for abscesses with intrahepatic biliary communication, the cure rates of percutaneous drainage for both groups were similar. Patients in whom an intrahepatic biliary communication was shown did not require alternative interventional or surgical measures for cure.

Adult↗
PubMed1979

[Brain abscess (Part 5)--Brain abscess following internal carotid occlusion (author's transl)].

Three cases of brain abscess following an occlusion of the internal carotid artery were reported. Case 1: A 6-year-old girl with congenital heart disease was admitted with headache, disturbance of consciousness and left hemiparesis. Right carotid angiography revealed an occlusion of the right internal carotid artery. After 6 months, she was readmitted with high fever. CT scan revealed a low density area and a ring-like shadow at the same site of cerebral infarction. Case 2: A 69-year-old man was admitted in semicoma and with right hemiplegia. Left angiography revealed an occlusion of the left internal carotid artery. After 2 months, a brain abscess was noted in the infarcted area. Case 3: A 20-year-old man with congenital heart disease, was admitted due to headache, vomiting and high fever. CT scan revealed a brain abscess in the right frontal lobe. Carotid angiography showed bilateral internal carotid artery occlusion. We concluded that diminution of cerebral oxygen and encephalomalacia are predisposing factors to the evolution of brain abscess.

Adult↗
PubMedDate not supplied

[Right subphrenic abscess secondary to amebic hepatic abscess].

Subphrenic abscess is a rare complication of amebic liver abscess, its diagnosis and treatment are problematic. We present one patient with a right subphrenic abscess secondary to amebiasis. Treatment with chloramphenicol and percutaneous drainage had good response. Radiological intervention is an option in treatment of this kind of complication.

Female↗
PubMed1979

Relevance of antibiotics in the treatment of brain abscesses. Report of a case with eight simultaneous brain abscesses treated and cured medically.

A case of eight simultaneous brain abscesses in the right cerebral hemisphere, treated medically after puncture of two of them, is reported. Antibiotics and hypertonic mannitol and, after seven days, dexamethasone were sufficient to cure these lesions. CT scan was of primary importance to follow the evolution under treatment. To get the best efficiency from antibiotics, identification of the microorganism and assessment of its resistance to antibiotics are necessary. It is suggested that in certain conditions medical therapy might be sufficient to treat cerebral abscess, after simple puncture to isolate the infecting agent. Corticosteroids should be avoided in the acute phase because they prevent antibiotics from penetrating the abscesses.

Adult↗
PubMed1991

[Intra-pulmonary suture abscess with hemoptysis after partial resection--concerning to the pathogenesis of the suture abscess].

A 53-year-old male with a intra-pulmonary suture abscess was admitted with recurrent hemoptysis. Five year before this admission, he had undergone a partial resection of the left upper lobe for pneumothorax using unabsorbable sutures (braided polyester). Chest CT showed tumor shadow in the left S1(+2) a on admission. Because of recurrent hemoptysis, left upper lobectomy was performed. Hemoptysis was due to the presence of a suture abscess. Pathological and clinical analysis of the intra-pulmonary suture abscess showed that it was caused not only by foreign body reaction but also transbronchial infection.

Hemoptysis↗
PubMed1975

[A clinical survey of brain abscess (3rd report): special reference to chronological analysis of EEG on brain abscess (author's transl)].

The attention of those concerned with the management of intracranial abscess has been largely directed to a study of the findings in clinicopathological and neuroradiological investigations. Our object, in this communication is to arouse interest in the electroencephalographic survey, especially chronological electroencephalographic study of absecess patients. The clinical material forming the basis of this study is drawn from a series of 46 consecutive cases of intracranial abscess treated, during 3 years, in the neurosurgical department of Tokyo Women's Medical College.

Adolescent↗