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At least 19 recordsLinked to original sources
PubMed1977

[Clinical results of two-time abortion technics with special regard to ascending genital infections].

If risk of the one-time mechanical dilatation will be too high (with young first gravidae and progressed pregnancy) the methods of the two-time interruptio should be applied. As long as there will not be available sufficient quantities of Prostaglandin-analoga the present method of choice is the abort-induction by means of the extra-amnial application of Prostaglandin F2alpha. In 101 cases when extra-amnial Pg F2alpha with an average induction time of four hours, the contamination rate was checked and no danger of ascension appeared. If prostaglandines will not be available, metranoicter or laminarias should be applied in the first trimenon when there is a high risk of dilatation, in the second trimenon extra-amnial instillation methods should be used. In both the cases only can be spoken of interruptios low if risks of they are made up under guard of broad spectrum antibiotics--after negative proof of blastomyces (buddings). This recommendation results from microbiological researches made up with 423 patients under the aspect of possible hospital infections. With induction times longer than 18 hours, the cavum uteri proved accelerating contaminated microbially. There were found microbes in the cavum uteri respectively at laminarias and metranoicters of, enterobacteria (45,7%), staphylococci (24,7%), hemolyzing and anhemolytic streptococci (17,6%), enterococci (8,0%), Corynebacteria (3,0%) and blastomyces (buddings) (1,0%).

Abortion, Induced↗
PubMed2004

Safe abortion: WHO technical and policy guidance.

In 2003, the World Health Organization published its well referenced handbook Safe Abortion: Technical and Policy Guidance for Health Systems to address the estimated almost 20 million induced abortions each year that are unsafe, imposing a burden of approximately 67 thousand deaths annually. It is a global injustice that 95% of unsafe abortions occur in developing countries. The focus of guidance is on abortion procedures that are lawful within the countries in which they occur, noting that in almost all countries, the law permits abortion to save a woman's life. The guidance treats unsafe abortion as a public health challenge, and responds to the problem through strategies concerning improved clinical care for women undergoing procedures, and the appropriate placement of necessary services. Legal and policy considerations are explored, and annexes present guidance to further reading, international consensus documents on safe abortion, and on manual vacuum aspiration and post-abortion contraception.

Abortion, Induced↗
PubMed1991

[Sacral epidural anesthesia as a method in technically complicated abortions].

An experience is reported with the use of epidural-sacral anesthesia for artificial abortion in 102 primiparae+- and nulligravidas and in 86 patients with scarring deformity or partial atresia of the endocervix. Two percent trimecaine was used in a single dose 6 mg/kg. A high efficiency of anesthesia was seen in 92% of cases. There was a significant relaxation of the cervix which facilitated cervical dilation and reduced the incidence of tissue injury. The population under study showed a lower incidence of intraoperative blood loss and early postabortal complications as compared with a population which received other anesthesia. These results suggest that epidural-sacral anesthesia is a promising technique for artificial abortion in primiparae+- and nulliparous women and in women with scarring cervical lesions.

Abortion, Induced↗
PubMed1996

Medically induced abortion in a woman with a large myomatous uterus.

For women with abnormal uterine anatomy that would make operative abortion technically difficult or impossible, a medically induced abortion may be the only option for pregnancy termination. Methotrexate and misoprostol were used to effect an early abortion in a woman with a markedly enlarged leiomyomatous uterus.

Abortifacient Agents, Nonsteroidal↗
PubMed2004

Advances in preimplantation genetic diagnosis.

Strategies for preimplantation genetic diagnosis (PGD) have become increasingly complex. For single gene disorders it is now usual for several DNA fragments to be simultaneously amplified using multiplex-PCR. This allows redundant diagnostic loci to be analyzed, reducing the chance of misdiagnosis due to allele dropout (ADO). Additionally, hypervariable 'fingerprinting' loci can be amplified, revealing the presence of DNA contaminants. Chromosomal screening has also increased in complexity. Current FISH techniques investigate up to nine chromosomes per cell and are offered to an increasingly wide range of patients, including women of advanced reproductive age and those with a history of repeated spontaneous abortion. Technical limitations, which preclude a full assessment of all chromosomes using FISH, have encouraged the development alternative tests. These include nuclear conversion, comparative genomic hybridization (CGH) and the use of DNA microarray 'chip' technology. This paper discusses technical innovations that have improved the scope and accuracy of PGD, as well as the emergence of new indications for PGD that are sometimes considered controversial (e.g. HLA-typing).

Blastocyst↗