Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Abdominal Cavity”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1990

[Qualitative and quantitative puncture examination of lateral canals of the abdominal cavity in closed abdominal injury].

The diagnostic puncture of lateral canals of the abdominal cavity in patients with closed trauma of the abdomen was made in 312 patients with associated trauma. Negative results were obtained in 166 patients. Retroperitoneal hematomas were diagnosed in 66 patients, reliable in 98.5%. In 80 patients injuries of the abdominal organs were diagnosed. The volume of intraabdominal blood loss (accurate within 80.7%) was determined before operation in 31 of them with the help of puncture with +/- 200 ml error. The diagnostic significance of lateral canals was 99.7%. Complications were the involvement of the liver in 4 patients not requiring any curative measures.

Abdominal Injuries↗
PubMed2002

A new abdominal cavity chamber to study the impact of increased intra-abdominal pressure on microcirculation of gut mucosa by using video microscopy in rats.

OBJECTIVE: In experimental studies of capillary blood flow that use intravital video microscopy, organs are exposed in observation chambers implanted into the animal. In this article we describe an abdominal cavity chamber for intravital video microscopy of gut mucosa microcirculation during increased intra-abdominal pressure. DESIGN: Prospective, experimental animal study. SETTING: Research laboratory at a university hospital. SUBJECTS: Male Wistar rats. INTERVENTIONS: The abdominal cavity chamber was designed for implantation into the abdominal wall of rats after laparotomy, thus creating an expanded hermetic, abdominal cavity volume. Animals were assigned to three levels of intra-abdominal pressure: controls (group 1), 10 mm Hg (group 2), and 15 mm Hg (group 3). Intra-abdominal pressure was increased by intra-abdominal insufflation of gas. By using a fluorescent marker, we quantitatively assessed mucosa perfusion index, functional capillary density, red blood cell velocity, capillary diameters, and flow motion during increased intra-abdominal pressure by intravital video microscopy. Results were expressed as mean +/- SEM. Significance of differences was determined by analysis of variance and multiple comparison of means with post hoc test (*p <.05 groups vs. control;p <.05 group 3 vs. group 2). MEASUREMENTS AND MAIN RESULTS: When compared with controls, animals subjected to an intra-abdominal pressure of 10 and 15 mm Hg showed a significant stepwise decrease in mucosa perfusion index (88%, 71%*, 22%*), functional capillary density (665.4 +/- 71.7, 461.6 +/- 71.9*, 375.1 +/- 2.0*cm(-1)), and red blood cell velocity (0.50 +/- 0.04, 0.33 +/- 0.03*, 0.04 +/- 0.06*mm/sec), indicating a stepwise impairment of mucosal microcirculation. Capillary diameters and flow motion did not change with respect to intra-abdominal pressure. CONCLUSIONS: This novel animal model of intravital intestinal video microscopy that uses an abdominal cavity chamber is a feasible and sensitive experimental tool to study intestinal microcirculation during increased intra-abdominal pressure. Intra-abdominal pressure likely results in a severe impairment of mucosal microcirculation.

Abdomen↗
PubMed2006

[Abdominal approaches and drainages of the abdominal cavity].

Appropriate access to the abdominal cavity is the first and crucial step for successful abdominal surgical intervention. In planning the incision, several variables have to be considered, such as anatomy of the abdominal wall, localization of the target organ, and individual conditions (previous incisions, minimal access surgery, etc). Medial laparotomy is the preferred incision for emergency cases and ill-defined pathologies, allowing access and hence exploration to all quadrants. Transverse laparotomies give superior access to the dorsal and right aspects of the liver and cause less pain in patients unfit for regional anesthetic procedures. Draining of the abdominal cavity is used after various resective and reconstructive procedures, but there is little evidence for its use in a number of operations such as gastric, hepatic, and colorectal resections. Advantages and disadvantages of different abdominal wall incisions and drainages are discussed.

Abdominal Cavity↗
PubMed1999

[Diagnosis of the increase of lymph nodes in the abdominal cavity].

Isolated abdominal lymphadenopathy is not such a common but a real diagnostic problem. Widespread prevalence of ultrasonography in routine diagnostics has been contributed to its greater recognition. In the first part of the article examinations which lead to the diagnosis (such as: microbiological examination, ultrasonography, CT, MRI, lymphography, histopathological examination) are discussed basing on the literature. The potential etiology of abdominal lymphadenopathy is described in the second part of the article. The characteristic changes are discussed for mentioned disease entities.

Abdomen↗
PubMed1991

[Fascia skeleton of the abdominal cavity--hernia and anorectal incontinence].

The abdominal cavity is the most primitive body cavity. Its musculo-fascial skeleton encompasses the abdominal wall, the pelvic floor, and the diaphragm. Comparative anatomical studies have demonstrated remarkable homology in the muscular and fascial architecture of each of these structures. In addition, all muscular sheets lining the abdominal cavity display a characteristic resting tone enabling them to act as a single functional unit. During pregnancy and childbirth the abdominal wall and the pelvic floor are prone to impairment from overstretching. This damage may result in postpartum paralysis of the abdominal wall or anorectal incontinence. Insight in the special anatomic and physiologic features of the abdominal muscle sheets may lead to a better understanding of the pathogenesis of primary and secondary abdominal hernias as well as postpartum anorectal incontinence and may improve surgical treatment.

Abdominal Muscles↗
PubMed1977

Water loss by evaporation from the abdominal cavity during surgery.

During abdominal surgery of different degrees of severity the evaporative water loss from wounds and exteriorized bowels was measured by recording the rate of vapour concentration increase in a closed measuring chamber placed over the exposed abdominal cavity. In an animal experiment on 4 rabbits the excessive evaporation of water from exteriorized bowels (15 g/h) gradually decreased and stabilized at approximately 50% of the initial value after 20 min of exposure. In surgical patients the loss by evaporation from a minor incision with only slightly exposed viscera was only 2.1 +/- 0.5 g/h, while moderate incisions with partly exposed but non-exteriorized intestines showed a loss of 8.0 +/- 1.0 g/h. During major exposure with exteriorized bowels a profuse evaporation of 32.2 +/-2.9 g/h was recorded. This evaporation constitutes an additional water loss of a magnitude exceeding the total cutaneous perspiration of healthy adults at rest. Simultaneously the surface temperature of exposed bowels fell by 3.5 degrees C. The evaporative water loss from abdominal exposures is of clinical importance only in time-consuming procedures comprising exposure and exteriorization of the intestines.

Abdomen↗
PubMed1997

[Gene expression and distribution in mouse abdominal cavity mediated by adenovirus].

Infection and expression of recombinant human adenovirus in mouse abdominal cavity was reported. After adenovirus vector Ad/RSV-beta-gal harboring the E. coli lacZ marker gene was injected into mice abdominal cavity, the peritoneal surface of jejunum, ileum, colon, uterus, liver, spleen, stomach, bladder, abdominal wall, diaphragm and testis was found large patches of lacZ-positive cells. But the adenovirus vector was not able to penetrate the peritoneum, as demonstrated by histochemical staining. Another adenovirus vector Ad/RSV-tk harboring the HSV-tk gene was injected into mouse abdominal cavity and the mouse was treated with ACV. No acute toxic reaction was observed. Based on these data, the feasibility of gene therapy of malignant tumor within abdominal cavity with adenovirus mediated TK/GCV system was discussed.

Abdomen↗
PubMed2002

Intraoperative and early postoperative chemotherapy into the abdominal cavity using gemcitabine may prevent postoperative occurence of peritoneal carcinomatosis.

BACKGROUND AND OBJECTIVES: Malignant tumors of various abdominal organs are blamed to be the cause of death in approximately 40% of cases per year in Western Europe. At the time of death, about half of them show peritoneal carcinomatosis which is considered an unfavorable prognostic factor. In case of peritoneal carcinomatosis, there is no curative treatment available for any of the tumors in the abdominal cavity. The aim of this experimental study was to evaluate the preventive potential of intra-operative or early postoperative local administration of gemcitabine into the abdominal cavity against peritoneal carcinomatosis. METHODS: Peritoneal carcinomatosis was induced in male WAG rats (n = 18) by transfer of 5 x 10(6) cells of the adenocarcinoma cell line CC-531 via minilaparotomy carried out in all rats under general anesthesia. Thirty days after cell transfer, rats were sacrificed and peritoneal carcinomatosis was confirmed using histologic investigation in specimens obtained from the peritoneal site. Extension of this carcinomatosis was quantified by (i) counting tumor nodes per square centimeter (mean of several counts) and (ii) determining tumor weight (weight of the greater omentum plus the resected mesentery). Rats were subdivided into three groups (n = 6 per group): group 1 (controls); group 2, simultaneously with tumor cell transfer 24 mg/kg of gemcitabine were administered into the abdominal cavity; group 3, postoperative intraperitoneal irrigation with 24 mg/kg of gemcitabine was achieved via a previously implanted port-a-cath on days(d) 15, 21, and 27. RESULTS: On the 30th postoperative day, all six animals of the control group showed extensive tumor growth at the peritoneum and greater omentum, indicating carcinomatosis. In contrast, none of the rats of group 2 revealed any traces of intraperitoneal tumor growth. While all rats of group 3 demonstrated intraperitoneal tumor growth, but early postoperative treatment with gemcitabine, however, resulted in a significant reduction of the number of tumor nodes and tumor weight in comparison with group 1 (controls). CONCLUSIONS: Immediate, i.e., simultaneous intraoperative application of a cytostatic agent such as gemcitabine into the abdominal cavity may completely prevent the generation of peritoneal carcinomatosis from occuring tumor cells, whereas early postoperative locoregional chemotherapy into the abdominal cavity can only reduce the severity of the peritoneal carcinomatosis.

Adenocarcinoma↗
PubMed1986

Human chorionic gonadotropin in early normal and pathologic pregnancy. Discordant levels in peripheral maternal blood and blood from the uterine and abdominal cavities.

Human chorionic gonadotropin was assayed in 25 cases after first-trimester induced abortion, in 45 cases of spontaneous abortion in the first trimester, and in 27 cases of ectopic pregnancy. Blood was obtained from an antecubital vein and from the uterine cavity. In the cases of ectopic pregnancy blood was also obtained from the abdominal cavity. In the group of induced abortion the human chorionic gonadotropin levels in peripheral maternal blood did not differ significantly from the levels in the uterine cavity. In the groups of spontaneous abortion and ectopic pregnancy the human chorionic gonadotropin levels were significantly higher in blood from the uterine cavity and the abdominal cavity, respectively. In four cases (three with spontaneous abortion and one with an ectopic pregnancy) human chorionic gonadotropin was not detectable in peripheral maternal blood, while it was found in blood from the uterine and abdominal cavities.

Abdomen↗