[Biological and psychological consequences of the induced abortion. Therapeutic abortion].
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Therapeutic abortion is proposed when a pregnancy threatens a woman's life and the fetus is not viable ex utero. As the intention is not to kill the fetus, this action should be named "therapeutic interruption of pregnancy". However, in some cases the fetus directly hampers the mother's health. Thus, the removal of the cause of the disease coincides with killing the fetus. Therapeutic abortion has been proposed for several situations. A) When pregnancy and not the fetus, impairs maternal life (e.g. ovular infection, ectopic pregnancy, decompensation of a preexisting disease or diseases of pregnancy as pre-eclampsia/eclampsia, HELLP and Ballantyne syndromes, choriocarcinoma). B) A risk for maternal survival caused by the embryo or fetal genetic constitution: autoimmune diseases of the mother generated by fetal antigens, some types of eclampsia with or without HELLP syndrome due to an immune or exaggerated inflammatory response of the mother, Ballantyne syndrome associated to eclampsia due to fetal-maternal genetic incompatibility, the classic fetus-maternal genetic incompatibility, embryo or fetus diseases caused by their genomic constitution, mainly hydatidiform mole and the triploid, or fetal cancer. Scientific knowledge and a prudential Medical Ethics are capable to solve most cases.
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Following therapeutic abortion in 280 patients prior to the 12th week of gestation, and amount of tissue aspirated was investigated. Measurement of the amount of tissue removed by vacuum suction after dilatation of the cervical canal showed a definite relationship between tissue quantity and gestational age. However, there was a wide range of tissue quantity in the various gestational age groups. The amount of blood lost during the procedure also depended upon gestational age. In 71% of the patients less than 100 ml was lost. There was no difference in the amount of blood lost between primigravidae and multigravidae when regard is paid to gestational age. No case of ectopic pregnancy was found. Re-evacuation was performed in 9 cases. The amount of tissue than recovered was small, in 7 cases 10 ml or less. Placental tissue was removed at re-evaluation in only one of these patients, decidua in all the others. It is concluded that measurement of the amount of tissue removed does not permit assessment of whether the uterine cavity has been adequately evacuated.
Therapeutic abortions in California have increased from 5,030 in 1968 to 15,339 in 1969, and over 60,000 are estimated for 1970. Also, there are pronounced regional differences in therapeutic abortions relative to live births. In 1969 the San Francisco Bay Area had six times as many abortions (115 per 1000 births) as did the Los Angeles Metropolitan Area (19). Preliminary figures for 1970 indicate this difference may be narrowed to a two-fold difference by the end of the year. Experience in other countries indicates morbidity and mortality risks are high in procedures done after the twelfth week, and in California one abortion in four is done after this period. Planning is needed to assure access to abortion services in all areas of the State and to meet the obligations of law and equity implicit in the Therapeutic Abortion Act. This should include counseling, follow-up, and referral services and not just the abortion procedure alone. Extension and more effective use of family planning services could substantially reduce unwanted pregnancies and the consequent demand for abortion. Efforts are also indicated to reduce the proportion of women terminating pregnancy after the twelfth week of gestation.Deaths associated with illegal abortions have decreased from 35 in 1966-1967 to 22 in 1968-1969. This is consistent with the view that the number of illegal abortions is decreasing.
Therapeutic abortion in the first trimester of pregnancy have been done in ten primigravidae using PGF2 alpha, 15-methyl-PGF2 alpha, or Sulprostone. Bleeding and recalcification time, platelet count, fibrin, platelet adhesiveness, partial thromboplastin time and thromboplastin time were examined before, during and after treatment. We found a decrease of platelet count and a prolongation of bleeding and recalcification time. There was no intensive-influence on coagulation system by the prostaglandin used. Therefore prostaglandins may be used for therapeutic abortion.
Therapeutic abortion during the first trimester of pregnancy was carried out as an out-patient procedure under local anaesthesia in 40 women. The intracervical injection of 1% mepivacaine resulted in satisfactory freedom from pain just as the paracervical injection. There was no dignificant difference in the intensity of pain in intracervical and paracervical local anaesthesia. The dilatation of the cervical canal was the determining factor for pain during the procedure. The intracervical and the paracervical local block are equally suitable for out-patient therapeutic abortion in our series.
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Surveys conducted after therapeutic abortion were used to evaluate contraceptive use, to assess early physical and emotional effects and to provide feedback to the hospital nurses on their counselling role. The follow-up rate was only 53%. Of those who cooperated 82.9% were using effective contraception three months after abortion. Subjective morbidity was greater than anticipated. The main emotional response was relief coupled with some guilt and depression in a significant minority. The occurrence and significance of the after effects of abortion should be explained in advance. Training workshops for abortion counsellors would be useful. The surgical termination of pregnancy is only a small part of a comprehensive abortion service.
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Chlamydia trachomatis was isolated from the cervix of 30 of 218 (13.8%) women admitted for legal termination of pregnancy. During the first two weeks after the abortion seven of the 30 (23.3%) patients developed pelvic inflammatory disease. Four of these had serological evidence of recent active chlamydial infection. Thus, routine examination of patients for genital chlamydial infection before termination of pregnancy is recommended.
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Pressures for interruption of pregnancy by therapeutic abortion constantly increase, both for liberalization of laws and for interpreting existing law more broadly. There are wide variations and inconsistencies in psychiatric attitudes and practices about therapeutic abortion. Follow-up patient data are scant, but necessary. Results of questionnaires indicate that such data can be obtained, and convey the impression that patients seem to manage after pregnancy, regardless of outcome, much as they had before pregnancy. This study indicates that the incidence of suicide in pregnant women is approximately one-sixth that of the rate for non-pregnant women in comparable age groups, implying that perhaps pregnancy has a psychically protective role.
Records of 606 therapeutic abortions performed by suction curettage, 693 interval laparoscopic sterilizations, and 442 combined procedures were analyzed and compared. The following conclusions were obtained: 1) Abortion alone and abortion with laparoscopic sterilization are similar in rates of postoperative morbidity (4.3 and 7%, respectively) and early complications (3.3 and 2.9%, respectively). 2) The risks in laparoscopic sterilization alone are significantly lower for postoperative morbidity (2.2%) and early complications (0.9%) than for abortion alone or for the combined procedure.
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