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PubMed1987

Chemical information science coverage in Chemical Abstracts.

For many years Chemical Abstracts has included in its coverage publications on chemical documentation or chemical information science. Although the bulk of those publications can be found in section 20 of Chemical Abstracts, many relevant articles were found scattered among 39 other sections of CA in 1984-1985. In addition to the scattering of references in CA, the comprehensiveness of Chemical Abstracts as a secondary source for chemical information science is called into question. Data are provided on the journals that contributed the most references on chemical information science and on the languages of publication of relevant articles.

Abstracting and Indexing↗

PubMedDate not supplied

Computational Science and Engineering Online (CSE-Online): a cyber-infrastructure for scientific computing.

With the expansion of the Internet and World Wide Web (or the Web), research environments have changed dramatically. As a result, the need to be able to efficiently and securely access information and resources from remote computer systems is becoming even more critical. This paper describes the development of an extendable integrated Web-accessible simulation environment for computational science and engineering called Computational Science and Engineering Online (CSE-Online; http://cse-online.net). CSE-Online is based on a unique client-server software architecture that can distribute the workload between the client and server computers in such a way as to minimize the communication between the client and server, thus making the environment less-sensitive to network instability. Furthermore, the new software architecture allows the user to access data and resources on one or more remote servers as well as on the computing grid while having the full capability of the Web-services collaborative environment. It can be accessed anytime and anywhere from a Web browser connected to the network by either a wired or wireless connection. It has different modes of operations to support different working environments and styles. CSE-Online is evolving into middleware that can provide a framework for accessing and managing remote data and resources including the computing grid for any domain, not necessarily just within computational science and engineering.

Engineering↗

PubMed1997

Assessment in basic science instruction: directions for practice and research.

In this essay, we discuss assessment of students' understanding of the basic biomedical sciences during the basic science component of medical education. Because we strongly believe that assessment should follow from and be congruent with course and curricular goals, the first section discusses recent trends in basic science education: where it's been and where it appears to be headed. The second section discusses considerations in the design of an assessment system that reflects curricular goals and encourages students to achieve them; it also identifies some research issues that we think merit attention. In the last section, we outline some of the special assessment issues and problems that arise in the context of problem-based learning (PBL) and discuss the merits of some of these novel assessment approaches, as well as the use of more traditional methods in PBL curricula.

Journal Article↗

PubMed2000

Does help in decision-making in biology help in decision-making in human sciences and conversely?

A link between biological and human sciences may be established, under the condition that we should admit the existence of reciprocal influences between them. The model for the regulation of agonistic antagonistic couples (MRAAC) is built from the study of biological systems and gives rise to specific types of control. This model can be helpful in decision processes in some human sciences such as management, economical and political strategies. The reason for such an opportunity lies in the fact that MRAAC is a general and phenomenological model able to incorporate the whole of the agonistic antagonistic systems. This type of regulation might be related to the concept of the viability of a system (yet also valid for human science systems) and to a functional and structural pattern which is the basis for agonistic antagonistic networks.

Biology↗

PubMed2003

On medicine as a human science.

All the powerful influences exerted by the subjective-interpersonal dimension on the organic or technical-functional dimension of sickness and health do not make an intersubjective test concerning medical therapeutic results impossible. These influences are not arbitrary; on the contrary, they obey "laws" that are de facto sufficiently stable to allow predictions and explanations similar to those of experimental sciences. While, in this respect, the rules concerning human action are analogous to the scientific laws of nature, they can at any time be revoked by becoming aware of them. Law-like and reproducible regularities in the sciences of man are by no means separated from a patient's personal-hermeneutic mediation. This makes it possible for human beings to modify, improve or sometimes even entirely (or better almost entirely) suspend these psychological, sociological, ethnological, medical, regularities. For this reason the sciences of man including medicine are under the obligation of constantly inspecting the continuing validity of the rules on which their predictions and explanations are based, namely by indirect, statistical methods. This requires a synergistic collaboration of extra-clinical and clinical tests through which medicine can obtain a good level of intersubjective testability.

Biomedical Research↗

PubMed1992

Redefining the science-practice relationship and professional training.

A revised conception of the relationship between psychological science and professional practice is proposed in the light of postmodern changes in perspectives on knowledge. Positivistic science, which has dominated the traditional interpretation of scientist-practitioner training, is considered from a constructivist point of view to be only one possible foundation of psychological knowledge. It is argued that the knowledge base of the profession should be derived with diverse methods and from multiple sources, including the knowledge of practice. The mutuality of science and practice is emphasized. An evolving framework for understanding the epistemology of practice, based on cognitive psychology, is presented. Emphasis on broadened choices of research methods, the development of reflective skills, and better linkage between teaching in the domains of research and practice are urged. Suggestions for research related to scientific training and the knowledge processes of practice are offered.

Forecasting↗

PubMed2005

Methodology in family science: introduction to the special issue.

Methodology influences every facet of scientific inquiry including the processes of framing questions, operationalizing constructs, sampling individuals within populations and observations within persons, analyzing data, and bringing meaning to the results. This introduction to the special issue on methodology emphasizes the recursive interaction of research methodology and theories underlying family science. Because the science of family psychology is richly complex, so too must the methods for examining couple and family phenomena be equally diverse. Articles comprising this special issue vary in their emphasis on research design versus data-analytic techniques and on confirmatory versus discovery-oriented strategies. The special issue is intended to advance not only the conduct of family science but also the understanding and integration of an increasingly complex research literature by those engaged in education and clinical interventions. ((c) 2005 APA, all rights reserved).

Journal Article↗

PubMed1995

Burnet oration. Politics, personalities and the development of science.

This lecture recounts a story that attempts to trace the history of ideas relating to tissue transplantation from the earliest times through to the present. This story was shaped by the strong Darwinian approach to biology championed by Burnet and Medawar. It also describes the political influence developed from the strong Lamarckian leanings of the communist supporters in the USSR, and the fact that the biological argument between those supporting Lamarck and those supporting Darwin was seen by the Praesidium of the USSR Academy of Sciences to be equated with the ideological class struggle between socialism and capitalism. This story points out that while science is valued for its objectivity, its dependence on personalities adds a subjective element. This subjective element is always present and it colours our science by reflecting both the political and cultural movements of the time.

Allergy and Immunology↗

PubMed1998

Measuring the unmeasurable: a caring science perspective on patient classification.

AIMS: To give a short historical survey of patient classification and its motives, to analyse patient classification and especially the instrument, The Oulu Patient Classification more closely from a caring science perspective. BACKGROUND: A survey of topical literature and research on patient classification show that economic and administrative justifications predominate and the caring science connection is weak, almost non-existent. ORIGINS OF INFORMATION: Topical literature and research on patient classification and the instrument, The Oulu Patient Classification. DATA ANALYSIS: Topical literature and research were evaluated from a caring science perspective in accordance with Eriksson's theory of caring and the basic concept of man as an entity of body, soul and spirit. KEY ISSUES: Patient classification is used in staff planning and is also justified from the viewpoint of content, that is, as a method of guaranteeing good quality in the care of patients and as an expression of the prevalent caring ideology. The concept of man is reduced in current literature and research on patient classification. The Oulu Patient Classification is based on a humanistic view of man, but man's spiritual and existential needs do not emerge clearly from the manual of the instrument. CONCLUSIONS: It is essential for patient classification to start from a caring perspective. Correctly dimensioned staffing based on patient classification is a prerequisite for good care. This should be combined with a caring culture that considers the whole complexity of man in order to make good care possible.

Activities of Daily Living↗

PubMed2001

Development and implementation of a science training course for breast cancer activists: Project LEAD (leadership, education and advocacy development).

OBJECTIVE: To develop and implement Project LEAD (leadership, education, and advocacy development), a science course for breast cancer activists. POPULATION: Students were breast cancer activists and other consumers, mainly affiliated with advocacy organizations in the United States of America. SETTING: Project LEAD is offered by the National Breast Cancer Coalition; the course takes place over 5 days and is offered 4 times a year, in various cities in the United States of America. RESULTS: The Project LEAD curriculum has developed over 5 years to include lectures, problem-based study groups, case studies, interactive critical appraisal sessions, a seminar by an 'expert' scientist, role play, and homework components. A core faculty has been valuable for evaluating and revising the course and has proved necessary to provide consistent high quality teaching. Course evaluations indicated that students gained critical appraisal skills, enhanced their knowledge and developed confidence in selected areas of basic science and epidemiology. CONCLUSIONS: Project LEAD comprises a unique curriculum for training breast cancer activists in science and critical appraisal. Course evaluations indicate that students gain confidence and skills from the course.

Adult↗

PubMed2006

Herbal medicine: the science of the art.

In the last 50 years science has provided new perspectives on the ancient art of herbal medicine. The present article discusses ways in which the evidence base for the professional use of 'Western' herbal medicine, as therapy to treat disease, known as phytotherapy, can be strengthened and developed. The evidence base for phytotherapy is small and lags behind that for the nutritional sciences, mainly because phytochemicals are ingested as complex mixtures that are incompletely characterised and have only relatively recently been subject to scientific scrutiny. While some methodologies developed for the nutritional sciences can inform phytotherapy research, opportunities for observational studies are more limited, although greater use could be made of patient case notes. Randomised clinical trials of single-herb interventions are relatively easy to undertake and increasing numbers of such studies are being published. Indeed, enough data are available on three herbs (ginkgo (Ginkgo biloba), St John's wort (Hypericum perforatum) and saw palmetto (Serenoa repens)) for meta-analyses to have been undertaken. However, phytotherapy is holistic therapy, using lifestyle advice, nutrition and individually-prescribed mixtures of herbs aimed at reinstating homeostasis. While clinical experience shows that this approach is applicable to a wide range of conditions, including chronic disease, evidence of its efficacy is scarce. Strategies for investigating the full holistic approach of phytotherapy and its main elements are discussed and illustrated through the author's studies at the University of Reading.

Chronic Disease↗

PubMed2003

Health science students' time organization and management skills: a cross-disciplinary investigation.

One hundred and fifty-four final year health science undergraduates from the disciplines of Medical Radiation Sciences, Speech Pathology and Physiotherapy in the Faculty of Health Sciences, the University of Sydney completed the Australian Time Organisation and Management Scale (ATOMS). Findings identified the strengths and weaknesses of students on the four dimensions included in this analysis. Whilst the results indicated strengths in the area of students' sense of purpose, level of focus and goal-setting ability, areas of weakness were noted, particularly with regard to the use of basic time-management devices (e.g. use of a diary and making lists). How these skills and competences are related to age, gender and discipline is explored. In addition, the degree to which these time-management behaviours can be enhanced (eg with time management intervention programs), the generalizability of the findings to other settings (non-academic), and the development of these skills over time are major issues discussed in the paper.

Administrative Personnel↗

PubMed2002

Problem-based compared with traditional methods at the Faculty of Medical Sciences, University of the West Indies: a model study.

The University of the West Indies (UWI) comprises three campuses located on three different islands. Two of the Campuses, Mona in Jamaica and St Augustine in Trinidad & Tobago offer full medical programmes, i.e. both basic sciences and clinical training. At Cave Hill, where basic sciences courses are not offered, students are drawn from the traditional school at Mona or the Problem Based Learning (PBL) school at St Augustine to follow a common clinical programme. After 24 months of clinical training consisting of a minimum of 12 clerkships these students take identical examinations in Medicine & Therapeutics, Surgery and Obstetrics & Gynaecology. In this paper the results of the final clinical examinations at Cave Hill for the five-year period 1995-99 have been analysed, comparing the performances of students drawn from Mona with those from St Augustine. We found that, except for a few isolated cases, there were no significant differences in the performance of the two groups of students. These results suggest that the delivery of a significant component of a basic sciences programme by a well-planned PBL system is unlikely to produce substandard students at the end of their clinical training.

Clinical Clerkship↗

PubMed2003

Biomagnetism: a new tool in sport and exercise science.

Biomagnetometry is a non-invasive technique for detecting magnetic fields associated with the electrophysiology and magnetic susceptibility of body tissues. The aims of this paper are to provide a review of the discipline of biomagnetism and its measurement using a superconducting quantum interference device (SQUID), and to discuss the potential utility of this technique in sport and exercise science. A tutorial section is presented to provide an introduction to the theory and practical application of SQUID biomagnetometry. A review of the biomagnetism literature demonstrates the variety of previous biomagnetic investigations and suggests several potential applications of biomagnetometry in sport and exercise science. A discussion of these includes an assessment of the advantages of measuring biomagnetic fields as opposed to electrical potentials, with particular reference to the improved precision and accuracy of physiological source modelling using biomagnetic data. There is evidence to suggest that SQUID biomagnetometry would provide useful (and perhaps unique) information on functional, anatomical and physiological assessments in sport and exercise science. Further investigations of biomagnetometry in this discipline should focus on three main areas: cardiology, encephalography and neurology, and body composition assessment.

Biophysical Phenomena↗

PubMed1999

A generalized rank-order method for nonparametric analysis of data from exercise science: a tutorial.

Frequent violations of the assumption that data are normally distributed occur in exercise science and other life and behavioral sciences. When this assumption is violated, parametric statistical analyses may be inappropriate for data analysis. We provide a rationale for using a generalized form of nonparametric analyses based on the Puri and Sen (1985) L treated as a chi 2 approximation. If data do not meet the assumption of normality, this nonparametric approach has substantial power and is easy to use. An advantage of this generalized technique is that ranked data may be used in standard parametric statistical programs widely available on desktop and mainframe computers, for example, regression, analysis of variance (ANOVA), multivariate analysis of variance (MANOVA) within BioMed, SAS, SPSS. Once the data are ranked and analyzed with these programs, the only adjustment required is to use a standard formula to calculate the nonparametric test statistic, L, instead of the parametric test statistic (e.g., F). Thus, rank-order nonparametric models become parallel with their parametric counterparts allowing the researcher to select between them based on characteristics of the data distribution. Examples of this approach are provided using data from exercise science for regression, ANOVA (including repeated measures) and MANOVA techniques from SPSSPC. Using these procedures, researchers can easily examine data distributions and make an appropriate decision about parametric or nonparametric analyses while continuing to use their regular statistical packages.

Analysis of Variance↗

PubMed2006

The development of an instrument for assessing Community-Based Education of undergraduate students of Community and Health Sciences at the University of the Western Cape.

CONTEXT: In Community-Based Education (CBE) students are expected to develop problem solving, communication and critical thinking capabilities. Assessment provides an opportunity for students to improve these skills, it helps them to gain increased motivation, high achievement, it reduces anxiety over grading, and it improves communication between learners and teachers. The aim of this study was to develop a common instrument for assessing undergraduate students of Health Sciences in their placements for CBE. OBJECTIVES: (1) Identify the skill requirements of students in CBE; (2) Develop a common instrument for assessing undergraduate students in Health Sciences. METHODS: The study was based in the Faculty of Community and Health Sciences at the University of the Western Cape. Existing documents relevant to the assessment of CBE were collected and analyzed to provide background information. Focus group discussions were held with lecturers from various departments, key persons from the departments and students were audiotaped and later the data analyzed into emerging themes. This was followed with a workshop by relevant experts in CBE, to identify the essential items to be included in the proposed assessment tool. The instrument was piloted with two departments in various community settings. RESULTS: The participants identified knowledge, transferable skills, professionalism and attitudes as important elements for assessment. The instrument piloted was very comprehensive and suitable for use by students of any profession in a range of communities. CONCLUSION: It is recommended that the instrument can be used to assess students in any learning experience based in a community setting.

Adult↗

PubMedDate not supplied

Science, politics and ethics in the low dose debate.

The roles of science, ethics and politics are identified in respect of the risks of exposure to low-dose radiation. Two case studies, the epidemiology of the United Kingdom nuclear test veterans and the risks to civilians associated with the military use of depleted uranium, are considered in the context of their ethical framing, scientific evaluation and political resolution. Two important issues for the present and future, the safe management of U.K. radioactive waste and the future of nuclear power, in which the science of low dose effects will be crucial and where the ethical issues are much more complex, are introduced. Specific consideration is given to the potential hereditary effects of ionising radiation in relation to the current state of radiobiological knowledge. It is concluded that for science to be useful in public health policy making there needs to be some reform from within the profession and the political imperative for freely independent scientific institutions.

Disaster Planning↗

PubMedDate not supplied

Lotka's law and the pattern of scientific productivity in the dental science literature.

Statistical regularities can be observed in many natural and social phenomena. From empirical data on the authorship of scientific papers, Lotka deduced an inverse-square law: the number of authors publishing n papers is 1/n2 of those publishing one paper. The general type for the relation (1/n(c)) has a wide range of applicability to a variety of phenomena. This study examined, by means of bibliometric tools, whether Lotka's law could be applied to the literature of dental science. Data came from 20 leading dental science journals, as reported in Journal Citation Reports. The search was performed with a programme developed using Visual Basic for Applications, which counted the number of authors and analysed their contributions to the literature. Authorship for all contributions, as reported in Medline, was compiled for each of these 20 journals for the last 25 years, 1971 through 1995. The total number of authors was 43,796, responsible for 124,556 authorships. The journals published in countries other than the USA exhibited higher degrees of author concentration. The dental science literature conformed very well to Lotka's model with c = 1.95.

Authorship↗