[Surgical obliteration of the endolymphatic sac in guinea pigs. Observations on a personal technic].
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Five hundred cases of head and neck injury, with a complete clinical audiological and vestibular investigation from a medico-legal point of view, were reviewed. Statistical correlations between the various objective and subjective parameters were analysed.
The delay between the stimulus and the voluntary eye saccade is the only parameter of the saccadic system which can be measured by using standard apparatus. Taking manually the measurements made on records obtained by using minicomputer; the authors show that such manual measurement of latencies is easy and yet sufficiently accurate to be of great clinical value. The latencies of voluntary saccades are normal in peripheral pathology (less than 250 milliseconds). Latencies of voluntary saccades are significantly increased in extrinsic brain stem lesions: tumours (in particular ponto cerebellar tumours), meningitis, head injury; but the velocity of the saccade is normal. This effect goes in parallel with impairement of the smooth pursuit. In intrinsic brain stem lesions (multiple sclerosis, acute brain stem stroke, oculomotor paralysis) latencies are increased bilaterally and above all, there is a significant slowing of the saccade. The role of fatigue increased latencies in some patients of this series. Two populations can be discerned in vestibular neuritis: one normal and one with abnormal smooth pursuit and increased saccadic latencies.
The program of the 18.5-day flight of the biosatellite Cosmos-936 included studies of physiological effects of prolonged weightlessness (20 rats) and artificial gravity (10 rats). The latter produced a normalizing effect on the function of the myocardium, musculo-skeletal system and excretory system. Simultaneously, artificial gravity exerted an adverse effect on the functions dependent on several sensors, primarily optic, vestibular and motor sensors. It is postulated that the adverse effects are associated with a relatively high rate of rotation and a short arm of the centrifuge.
Visual stimulation can provoke egocentric illusory movements or changes of posture. Therefore, vestibulo-spinal tests were usually performed with eyes closed. A more sensible method seems to be the "visual stabilization", which is obtained by means of a box fixed on the head and with eyes open. In this manner, body instability due to vestibular disorders becomes more apparent.
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