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Malathion for treatment of Pediculus humanus var capitis infestation.

One hundred fifteen subjects took part in a double-blind study comparing the efficacy and safety of 0.5% malathion lotion (Prioderm lotion) and the alcoholic vehicle of the lotion as pediculicides in the treatment of head lice. The subjects, with a mean age of 9 years, had long-standing lice infestations and at least 20 viable ova. The subjects were treated with the test preparation, which was allowed to remain on the hair for 12 hours. Ovicidal and pediculicidal efficacy for the malathion lotion was significant; overall clinical evaluation by the investigators showed a significant number of moderate to marked therapeutic responses to malathion lotion. Only one adverse reaction (in the malathion lotion group) was reported, the stinging of pyodermal lesions in reaction to the alcoholic vehicle. Other concomitant scalp diseases were unchanged or improved at the end of the study.

Administration, Topical↗

Systemic sarcoidosis with necrobiosis lipoidica-like scalp lesions.

A 78-year-old woman is described, having systemic sarcoidosis for 15 years, involving the lungs, lymph nodes and the skin. Over the last 6 years she developed a progressive cicatricial alopecia with histologic changes of the granulomatous type of necrobiosis lipoidica surrounded by sarcoid granulomas.

Aged↗

[Mixed dermatophytic infection of the hairy scalp].

A mixed infection induced by Microsporum canis and Trichophyton tonsurans has been observed on the scalp of a 10-year-old girl. Microscopy has shown microsporum-type endo-ectothrix parasitism on some hairs, whereas others exhibited a strictly trichophyton-type endothrix parasitism. This double parasitism was confirmed histologically (PAS coloration), and M. canis and T. tonsurans could be cultured. The infection was eradicated after 5 weeks of treatment with griseofulvin (750 mg/day per os) and local application of 1% Econazol spray solution twice a day.

Child↗

[Dowling-Degos disease with involvement of the scalp].

Dowling-Degos disease is described in a 40 year-old man, involving the nape of the neck, axillary regions, scrotum, intergluteal fold and also the scalp. There was no associated hair growth anomaly. There was extensive pitting of the entire face. Dowling-Degos disease appears to result from a genetically determined imbalance of epithelial-mesenchymal regulatory mechanisms causing increased epithelial proliferation, as well as a disturbance of the maturation and differentiation of the proliferating keratinocytes.

Adult↗

[Notes about cutis verticis gyrata (author's transl)].

A case of so-called, "Pseudo"-Cutis verticis gyrata naevocellularis is described. The possible malignant degeneration of this disease, which can also be described as "cerebriform intradermal nevus" is discussed. In this context, a classification of the "Cutis verticis gyrata" is suggested.

Adult↗

[Plastic surgery after extensive tumor surgery of the scalp].

Extensive resections of tumors of the scalp penetrating into the bone and the brain often require the use of free flaps for coverage as the only possibility. Four cases are reported and the specific problems of these microsurgical operations in this region are discussed.

Adult↗

[Microsporous infection of the scalp in an adult (author's transl)].

Infection of the scalp in an elderly woman due to Microsporum canis (zoophilic, long-lived fungus) after repeated direct contact with infected cats. We think that the infection could occur because of an age-induced decrease in some of the organic functions which govern the healing process of microsporous infections during puberty.

Aged↗

[Folliculitis decalvans].

A 58 year-old-male with folliculitis decalvans, a circumscribed chronic purulent folliculitis with subsequent hair loss and follicular atrophia is described. Staphylococcus aureus haemolyticus could be detected in the lesions. Local and systemic treatment with fusidic acid was effective.

Alopecia↗