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PubMed2002

Toward a revised evolutionary adaptationist analysis of depression: the social navigation hypothesis.

Evolutionary biologists use Darwinian theory and functional design ("reverse engineering") analyses, to develop and test hypotheses about the adaptive functions of traits. Based upon a consideration of human social life and a functional design analysis of depression's core symptomatology we offer a comprehensive theory of its adaptive significance called the Social Navigation Hypothesis (SNH). The SNH attempts to account for all intensities of depression based on standard evolutionary theories of sociality, communication and psychological pain. The SNH suggests that depression evolved to perform two complimentary social problem-solving functions. First, depression induces cognitive changes that focus and enhance capacities for the accurate analysis and solution of key social problems, suggesting a social rumination function. Second, the costs associated with the anhedonia and psychomotor perturbation of depression can persuade reluctant social partners to provide help or make concessions via two possible mechanisms, namely, honest signaling and passive, unintentional fitness extortion. Thus it may also have a social motivation function.

Adaptation, Psychological↗

PubMed2002

Partners-in-infection: host proteins involved in the transformation of plant cells by Agrobacterium.

Genetic modification of plant cells by Agrobacterium is the only known natural example of DNA transport between kingdoms. While the bacterial factors involved in Agrobacterium infection have been relatively well characterized, studies of their host cellular partners are just beginning. Here, we describe the plant cell factors that might participate in Agrobacterium-mediated genetic transformation and discuss their possible roles in this process. Because Agrobacterium probably adapts existing cellular processes for its life cycle, identifying the host factors participating in Agrobacterium infection might contribute to a better understanding of such basic biological processes as cell communication, intracellular transport and DNA repair and recombination as well as help expand the host range of Agrobacterium as a genetic engineering tool.

Active Transport, Cell Nucleus↗

PubMed2005

Roles of initiation and responsiveness in access and participation for children with specific language impairment.

This study compared the abilities of children with specific language impairment (SLI; n = 10) and typically developing (TD) children (n = 13) to access and participate in an ongoing interaction between two unfamiliar peer partners. Results revealed that all children in the study accessed by either making an unprompted initiation toward their peers (access initiation) or by responding to a question or play invitation directed toward them (access response). However, 4 children with SLI were unsuccessful in achieving successful access initiation during the 10-min play period. Children with SLI required a longer period of time to achieve access initiation. Following access, children with SLI were addressed significantly less by their play partners, participated in less group play, and engaged in more individual play and onlooking behavior. Among the SLI group, language levels were negatively related to the time children required to achieve their first successful access and first access initiation. Expressive language levels were positively related to the percentage of utterances children produced postaccess and the percentage of utterances they were addressed postaccess by their play partners. Differences in receptive skills among SLI children were less strongly related to the time they required in achieving their first access and were unrelated to their ability to participate in the interaction.

Child↗

PubMed2004

The school, a viable educational site for interdisciplinary health promotion.

BACKGROUND: An interdisciplinary health promotion module, using the community-based teaching approach, is offered by the University of the Western Cape (UWC). Schools in Delft, a poor socio-economic area with high unemployment, crime and a range of social problems, are used as the teaching site. AIM: To assess the status of the health promotion initiatives in schools where students were placed. METHOD: A self-administered structured questionnaire for teachers and principals. Variables included were demographic data, views of health promotion, health promotion activities at the school, barriers and opportunities to implement health promotion activities. RESULTS: A response rate of 68.75 % (n = 55) for teachers and 100 % (n = 4) for principals was obtained. Most (87%) teachers felt that health promotion has a place within the curriculum. They reportedly focused on topics related to health within the school curriculum. Partners, such as public health nurses, university students, and a pharmaceutical company, offer additional health promotion initiatives. These include general health checks, HIV/AIDS information, adolescent health and dental health. Barriers to initiate and sustain programmes include lack of resources, insufficient staff training, lack of commitment by both teaching staff and the community, insufficient time, the heavy workload of teachers, and communication problems as a result of language barriers. Only 36% of teachers felt the school environment was conducive to learning. CONCLUSION: Health promotion initiatives in the schools concerned are uncoordinated, erratic, based on the resources that the school has access to at a given time and the demands of the curriculum.

Adult↗

PubMed1997

What mothers do to support infant visual attention: sensitivities to age and hearing status.

This article presents a descriptive, longitudinal study of maternal use of communicative strategies to accommodate and direct infant visual attention. The two questions that guided our research were whether maternal use of particular attention-related strategies changed as the child developed from 9 to 18 months of age and whether the mother's ability to make appropriate modifications in strategy use was disrupted when she was using a new mode of communication. Four groups of mother-infant dyads were included: deaf mothers with deaf children (Dd), hearing mothers with deaf children (Hd), deaf mothers with hearing children (Dh), and hearing mothers with hearing children (Hh) (n = 77). When the infants were 9, 12, and 18 months old, they were videotaped while they engaged in free play with their mothers. Using a time-sampling technique, videotapes were coded to determine the frequency with which mothers used specific attention-related strategies. Our findings showed group differences in the attention-related strategies used by deaf and hearing mothers. These group differences were consistent with the hypothesis that while mothers appeared to be sensitive to and tried to accommodate their children's communication needs, the mothers may have been limited by their own communicative experiences. With regard to changes in mothers' use of attention-related strategies over time, our hypothesis of a developmental transition in the chosen strategies was only partially supported. Attention strategies related to language did evidence a pattern of developmental progression; however, maternal use of strategies that directed the children's visual focus to an object or a social partner did not show any such trend. Overall, the patterns indicated in the data from this study suggest that bidirectional influences were operating to some degree in each of the four groups. Among mothers whose hearing status differs from their children, the use of certain attention-related strategies might need to be taught, particularly the use of specific strategies that may scaffold deaf infants' developing abilities to alternate attention between objects and persons.

Journal Article↗

PubMed2003

The use of needle exchange by young injection drug users.

This study analyzed factors associated with utilization of needle exchange programs (NEPs) by young injection drug users (IDUs). Between 1997-1999, 700 IDUs 18-30 years of age were surveyed in Chicago. The majority of study participants (65%) had not used an NEP in the 6 months preceding baseline. Frequent NEP users were least likely to share needles (odds ratio [OR] = 0.32; 95% CI = 0.19-0.54) or other injection equipment (OR = 0.51; CI = 0.30-0.85), or to reuse their own needles (OR = 0.25, CI = 0.13-0.45), and were most likely to use condoms with steady sex partners (OR = 2.95; CI = 1.56-5.56). This study found that while frequent NEP use was associated with less risk behavior, young IDUs used NEPs infrequently or not at all.

Adolescent↗

PubMed2004

Inter- and intracellular interactions of Nogo: new findings and hypothesis.

The molecule Nogo has captured the imagination of many as a possible key player, and therefore therapeutic target, in the pathological settings of central nervous system (CNS) injury and degenerative pathology. Found in both glial cells and neurons, the endogenous, physiological role of Nogo is as yet unknown. Recently reported targeted disruption of the Nogo gene did not result in any obvious neuro-anatomical or neurological phenotype. Compared with wild-type mice, Nogo-deficient mice also did not exhibit a truly convincing enhancement in their ability to regenerate CNS neurons upon injury. Does the molecule have any important physiological function at all? Other recent discoveries of new interacting partners of Nogo at the mitochondria and the CNS paranode suggest intriguing links to the modulation of apoptosis and developmental organization or signalling at the axoglial junction.

Animals↗

PubMed2002

Is there a need for rescreening of patients treated for genital chlamydial infections?

The present communication reviews reasons to perform rescreening of chlamydia-infected persons. It brings up difficulties to differentiate between relapse and reinfection. Studies on follow-up of chlamydia-positive cases after therapy are reviewed. It also highlights reasons for therapeutic failure, like compliance, pharmacological factors, including poor bioavailability, wrong dose regimens, lack of adherence to drug intake, neglect of partner notification and concomitant therapy in consorts, possible development of resistance to drugs generally prescribed, false negative or false positive diagnostic tests and reinfection from extra-genital not 'cured' sites. The review points to the need to establish programmes for routine rescreening of chlamydia-infected persons.

Antifungal Agents↗

PubMed2003

Benchmarking information needs and use in the Tennessee public health community.

OBJECTIVE: The objective is to provide insight to understanding public health officials' needs and promote access to data repositories and communication tools. METHODS: Survey questions were identified by a focus group with members drawn from the fields of librarianship, public health, and informatics. The resulting comprehensive information needs survey, organized in five distinct broad categories, was distributed to 775 Tennessee public health workers from ninety-five counties in 1999 as part of the National Library of Medicine-funded Partners in Information Access contract. RESULTS: The assessment pooled responses from 571 public health workers (73% return rate) representing seventy-two of ninety-five counties (53.4% urban and 46.6% rural) about their information-seeking behaviors, frequency of resources used, computer skills, and level of Internet access. Sixty-four percent of urban and 43% of rural respondents had email access at work and more than 50% of both urban and rural respondents had email at home (N = 289). Approximately 70% of urban and 78% of rural public health officials never or seldom used or needed the Centers for Disease Control (CDC) Website. Frequency data pooled from eleven job categories representing a subgroup of 232 health care professionals showed 72% never or seldom used or needed MEDLINE. Electronic resources used daily or weekly were email, Internet search engines, internal databases and mailing lists, and the Tennessee Department of Health Website. CONCLUSIONS: While, due to the small sample size, data cannot be generalized to the larger population, a clear trend of significant barriers to computer and Internet access can be identified across the public health community. This contributes to an overall limited use of existing electronic resources that inhibits evidence-based practice.

Attitude to Computers↗

PubMed2004

The experience of the support person involved in a lung transplant programme: results of a pilot study.

UNLABELLED: In contrast to the high priority most transplant programmes give to the recipient's support system there is a paucity of studies referring to the experience of the respective support persons. This study sought to focus on the subjective burden of support persons and their unmet needs. METHOD: A questionnaire was designed for a cross-sectional study using numerical rating scales and fill-in-the-gap-items concerning subjective burden, stress symptoms, unmet needs, suggestions to improve the support person's situation. Participants were 39 relatives of adult transplant patients (22 cystic fibrosis transplant recipients, 17 recipients with other aetiologies) who had transplants 5 years ago (mean). RESULTS: The acute illness stage was rated as extremely stressful by most of the respondents. However, even during the rehabilitation period, one third described themselves as very stressed. Stress related symptoms at or post transplant were reported by 82% of respondents (more mothers than partners). Symptoms mostly referred to depressive and anxiety states. Most support persons had to tackle organizational difficulties in order to stay with the recipient and faced financial burdens not refunded by agencies. Support persons made suggestions to improve the recipient's situation and those of other support persons. Regarding the recipient their advice referred to enhanced information giving, aspects of communication and better access to psychosocial professionals. Regarding another support person they suggested to be well-informed beforehand and to remain optimistic. CONCLUSIONS: Mothers in this study seemed to be particularly vulnerable as support persons and thus deserve special attention. Few resources may be needed to achieve considerable benefit for the support person, such as arranging accommodation or identifying a team member to relate to.

Adult↗

PubMed2006

Parental communication and youth sexual behaviour.

The role of parental communication and instruction concerning sexual behaviour were studied in a community-based sample of 1083 youth aged 13-17 (mean age of 15 years; 51% girls, 49% White). The Youth Asset Survey was administered along with items measuring demographics and youth risk behaviours. After controlling for demographic factors, multivariate analysis revealed that youth were much less likely to have initiated sexual intercourse if their parents taught them to say no, set clear rules, talked about what is right and wrong and about delaying sexual activity. If youth were sexually active, they were more likely to use birth control if taught at home about delaying sexual activity and about birth control. Having only one sexual partner was associated with having an adult role model who supports abstinence, being taught at home about birth control, and being taught at home how to say no. If parents reported talking with youth about birth control and sexually transmitted disease (STD) prevention, youth were significantly more likely to use birth control. Our conclusion is that parents have the opportunity and ability to influence their children's sexual behaviour decisions.

Adolescent↗

PubMed2000

Women with learning disabilities: risk behaviours and experiences of the cervical smear test.

This paper reports the findings of a study on the views and experiences of women with learning disabilities regarding the cervical smear test. The experience and opinions of the carers were also taken into account. The study was carried out between 1997 and 1999 in Cambridgeshire. The factors that influenced whether women with a learning disability had a smear test included: sexual activity; number of sexual partners; pregnancy; and a past history of smoking. Women with a learning disability who had a cervical smear test most often experienced pain and difficulty with the procedure. Factors that enable women with a learning disability to undergo a cervical smear test, according to their experiences, will be discussed in this paper. These include: the importance of prolonged preparation; issues surrounding communication; the giving of information; and support from the carers. The implications of these findings for collaborative working between learning disability nurses and primary healthcare professionals in clinical practice are highlighted.

Adult↗

PubMed2005

[Health monitoring on a federal level. Approaches and perspectives].

An assessment of the existing elements of a health monitoring system in Germany is given. Based on the analysis of deficits, the necessity for a comprehensive health monitoring system is recognised. The authors suggest starting points for the development of such a system in Germany by integrating different actors and taking into account different interests. The proposed system is based on a modular principle and allows for continuity as well as flexibility. As one key element in this monitoring system, a longitudinal health study is suggested, which allows the observation of developments in health matters as well as the evaluation of health policy actions. A plan for the step-wise development and testing of the health monitoring system is presented. Cooperation and data networking are essential elements. Whereas the flexible parts of the monitoring system should be financed by interested partners and customers, a basic sustainable financial support is a prerequisite. This paper provides arguments for the implementation of a health monitoring system and the need for long-term funding.

Cohort Studies↗

PubMed2006

'The most disgusting ever': children's pain descriptions and views of the purpose of pain.

This article examines an area of a larger research project, aimed at investigating hospitalized children's experiences of pain. Descriptions of pain and views regarding the purpose of four to 11-year-old children's pain were investigated. A total of 44 hospitalized children participated in the study. The data were collected by means of a qualitative interview with the children. Using qualitative content analysis, interviews were coded and categories identified. Participant descriptions aimed at generalizing the pain. The children specified the nature of the pain and used paraphrases and metaphors. The study demonstrated that most of the children were able to articulate the purpose that they ascribe to their pain. The findings challenge nursing staff to regard the suffering child as an active partner in assessing their pain. An enhanced understanding can better prepare nurses for participating in the management of hospitalized children's pain.

Adaptation, Psychological↗

PubMed1997

The technology of benefits outsourcing: helping employees help themselves.

The exponential growth of health plan offerings and increased use of defined contribution retirement plans has caused a fundamental shift in the way that benefits management is done. Specifically, the authors point out that we are moving into an era of "self-service" in employee benefits, with employees often taking the role of management of their own benefits through use of technology. Outsourcing benefits management through the use of technology has meant the role of HR departments has shifted from personnel administrators to strategic business partners. By outsourcing administrative functions and maximizing the power of new interactive technology, human resource departments are able to focus on the strategic needs of the company to adapt to the challenges of the future.

Computer Communication Networks↗

PubMedDate not supplied

The influence of significant others on Australian teenagers' decisions about pregnancy resolution.

CONTEXT: Teenagers' decisions about how to resolve a pregnancy are made in the context of a society, a family and a relationship with a partner. Little is known about how such decisions are made, however, particularly in Australia. METHODS: The association between the influence--both direct and indirect--of significant others and adolescent women's decisions to terminate or continue a pregnancy is examined here using data from a case-control study on 1,324 pregnant teenagers in Australia. Bivariate analyses were used to explore the association between pregnancy resolution and direct or indirect influence toward abortion or birth. Multivariate logistic regression analyses were used to model the association between significant others' influence and teenagers'pregnancy resolution decisions while controlling for adolescent women's background characteristics. RESULTS: Teenagers who reported that their partner influenced them toward abortion had significantly increased odds of choosing abortion (10.4), and those whose partner influenced them toward motherhood had significantly reduced odds of choosing abortion (0.5). Direct influence from parents toward either abortion or motherhood was not significantly associated with teenagers' decisions. Mothers are an important source of indirect influence, however: Teenagers whose mother had become a mother as a teenager had reduced odds of choosing abortion (0.4), and those whose mother had ever had an abortion had increased odds of choosing abortion (2. 1). Teenagers who had a sister who had ever had an abortion had significantly increased odds of choosing abortion (2.4). CONCLUSION: While most young women report they were not directly influenced by a significant other in their decision to continue or terminate a pregnancy, pregnancy resolution decisions are affected by families and partners, often indirectly. These findings have important implications for the manner in which services are delivered to these young women.

Abortion, Legal↗

PubMed2004

The National Action Plan for the Prevention and Control of Non-communicable Diseases and Health Promotion in Pakistan--Prelude and finale.

In Pakistan a public-private partnership--led by the NGO Heartfile and constituted additionally by the Ministry of Health, Government of Pakistan and the WHO Pakistan office--was launched in April 2003. Mandated with the task of developing and implementing a national strategy for achieving national goals for the prevention and control of non-communicable diseases (NCDs). This was the first opportunity to mount a truly 'National Plan of Action' in Pakistan enlisting a broader range of inputs and with the Governments commitment to NCD as a priority. The partnership recently released a strategic framework for action--the National Action Plan for the Prevention and Control of Non-communicable Diseases and Health Promotion in Pakistan (NAP-NCD)--an integrated and concerted approach addressing the multidisciplinary range of issues within a prevention and control framework across a broad range of NCDs. Incorporating both policies and actions and set within a long-term and life course perspective, NAP-NCD calls for an institutional, community and public policy level change factoring integration at four levels: grouping NCDs so that they can be targeted through a set of actions, harmonizing actions, integrating actions with existing public health systems and incorporating contemporary evidence-based concepts with this approach. The NAP-NCD delivers an Integrated Framework for Action, which has been modelled to impact a set of indicators through the combination of range of actions in tandem with rigorous formative research. Drawing on the strengths of various public and private sector partners, this programme outlines a scope of interventions that are built on shared responsibility, allowing agencies to participate according to their own missions and mandates. The partnership is in harmony with national health priorities, complements state initiatives and is optimally integrated with the national health system. The partnership has brought value to all the three partners. The government has harnessed the technical strength of a private sector partner, which in turn is contributing to the country's National Plan within the framework of priorities set by broad-based national consensus; WHO, on the other hand, is gaining experience in working in a country model in which the private sector can be supported through WHO country resources, which are typically earmarked for public sector initiatives. Work is currently underway to implement the first phase of NAP-NCD.

Communicable Disease Control↗

PubMed2001

The development of commitment and attachment in dating relationships: attachment security as relationship construct.

This study examined attachment security and commitment as predictors of relationship stability in a sample of 51 couples. Attachment and commitment were measured during the Fall and Spring semesters prior to graduation from college and relationship stability was determined by contacting couples approximately one year following graduation from college. Attachment security was measured as a relationship construct (appraisal of the dating partner's availability and responsiveness). Attachment security increased with the length of time in the dating relationship and predicted relationship stability following graduation. We then considered how personality and family of origin factors contributed to positive trajectories within the dating relationship (i.e. the growth of attachment security, commitment and relationship stability). Males' security with their mothers and fathers and reports of open communication between their parents contributed to growth in attachment security and commitment between the Fall and Spring semesters. Attachment styles (assessed as a measure of personality) also predicted relationship stability with both males' and females' security increasing the relationship stability one year after graduation. Implications for understanding attachment as both a personality and relationship construct in adult romantic relationships are discussed.

Adult↗