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Spinal cord injury: what is the effect on sexual response?

In this paper the sexual response cycle and neurologic pathways involved in sexual functioning are reviewed. This is used as a foundation to review the spinal cord injury literature and examine what is primarily self-reported regarding sexual function with varying types of spinal cord injury. A recommendation is made for more thorough, objective studies through which hypotheses can be tested and a foundation built for prognostication of how sexual functioning will be altered after varying types of SCI.

Ejaculation↗

A review of the effect of traumatic brain injury on the human sexual response.

A human sexual response format was used to describe possible sexual dysfunctions after TBI. Additional material was also included to qualify the information drawn from the above format. A number of possible conclusions were drawn, indicating that the causes and effects of sexual functioning after TBI are very confusing and that the literature does not clarify this confusion. One cannot accurately differentiate between primary and secondary sexual problems and, therefore, cannot evaluate the contribution of each problem to the presented sexual dysfunction.

Adult↗

Sexuality in women.

Explore the source record for details and available documents.

Female↗

Sexuality in Montreal women living with HIV.

The impact of learning a positive HIV test result on the sexuality of 161 women (47 injection drug users (IDU), 53 non-IDU women of Haitian or African origin (non-IDU-HA), and 61 non-IDU Caucasian women (non-IDU-C) was assessed using closed and open-ended questions. Self-reported CD4+ count correlated with any post-test (p = 0.001) and past month sexual activity (p = 0.007). After learning their HIV status, 110 women (68%) were sexually active, 48 (44%) of these within 1 month. After resuming sexual activity, 84% underwent a sexual adjustment period (median duration 8.5 months). IDU women were more likely to have frequent sex, be anorgasmic, and prefer sex less often. Consistent partner condom use was low in general (19% for IDU, 30% for non-IDU-HA, and 62% for non-IDU-C) and by partner type (new regular partner 58%, same regular partner 36%, casual partner 29%). Sexual satisfaction tended to decline post-test and then increase to higher than pre-test levels. Counselling focused on the safe and satisfying aspects of sex may assist women with HIV infection in sexual decision-making. Facilitating the access of IDU women with HIV infection to medically supervised drug provision and to detoxification and rehabilitation programmes can weaken the link between drug use and sex work.

Adolescent↗

Treating sexual dysfunction in dialysis and transplant patients.

Sexual dysfunction can be a significant problem for patients with end-stage renal disease and other chronic or disabling conditions. To a large extent, however, social workers and other professionals have overlooked the special needs of patients whose sexual capacities have been affected by illness or injury. This article presents an assessment and treatment model for helping such patients.

Counseling↗

History-taking in sex counseling.

A formula for obtaining a sexual history that has both diagnostic and therapeutic significance has been presented. By utilizing the relationship between effective stimulation of a sufficient quantity in a nuturing environment, the physician will be able to clarify what has either caused or is maintaining the sexual difficulty. It will be most beneficial if the physician explains the history-taking approach to the woman. In this way she can see how her answers relate to the problem and to the direction of treatment. A history-taking approach structured in this manner is most helpful to the physician and the woman.

Adult↗

Dyspareunia and vaginismus.

Dyspareunia and vaginismus are discussed to present information and a structural concept allowing the gynecologist to evaluate these conditions. The presence of subtle pelvic organic factors is frequently found in dyspareunic women referred for sex therapy by physicians. Thus a need for scrupulous evaluation, including laboratory work and other diagnostic tests, with close attention to the history of the patient is urged. In the remaining dyspareunic women and in those with vaginismus, a psychophysiologic conditioned response is present. Treatment approaches are discussed and the techniques of perineal muscle exercise and vaginal self-dilation are presented in detail. Used appropriately, these techniques produce a very high symptom elimination rate in these female sexual dysfunctions.

Dilatation↗

Side effects as predictors of drug response in obsessive-compulsive disorder.

Differences between the side effect profiles of clomipramine (CMI) and the selective serotonin reuptake inhibitors may be important factors in both treatment outcome and patient selection in obsessive-compulsive disorder (OCD). Safety and efficacy data from an industry-sponsored, multicenter clinical trial of CMI were analyzed previously using tabular and multiple regression methods. Good response, defined as at least a 35% drop in final scores on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), was associated with a later age of OCD onset and certain early side effects that may reflect a sensitivity of responders to CMI's serotonergic actions. The authors conducted a similar analysis of data from an industry-sponsored clinical trial of fluoxetine in OCD. Fluoxetine response did not seem to be associated with age of OCD onset. Good response to both drugs was associated with initial nervousness and sexual complaints. The common side effects of fluoxetine (headache, nausea, and gastrointestinal complaints) did not seem to be associated with treatment response. Slight differences in the protocols of the two clinical trials yielded patient populations that were different in factors found to be associated with treatment outcome: subjects in the fluoxetine study had lower scores on the Y-BOCS, higher scores on the Hamilton Rating Scale for Depression, and an earlier age of OCD onset.

Adolescent↗

A case of moclobemide-induced hyperorgasmia.

Moclobemide-induced sexual hyperarousal of a female patient is presented. Remarkable similarities with a previously reported case and implications of the phenomenon are discussed.

Adult↗