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PubMed1998

Imaging sports injuries: the future.

OBJECTIVE: To review the application of new imaging technologies to the practice of sports medicine. DATA SYNTHESIS: Musculoskeletal imaging has dramatically evolved over the past decade. Plain film acquisition, archiving, storage, and interpretation have undergone revolutionary changes, moving into the electronic era. Viewing hard-copy film is becoming obsolete as digital image acquisition and display will eventually render radiology departments filmless. Although it seems unlikely that a new modality will enter the imaging arena in the near future, we will continue to see the development of software and hardware technology that allows rapid acquisition of superior quality cross-sectional image data. CONCLUSION: As these technologies continue to flourish, diagnosis and treatment planning of the injured athlete will become both more expedient and more accurate.

Athletic Injuries↗
PubMed2000

The relationship of physical trauma and surgical stress to menstrual dysfunction.

To evaluate the incidence and pattern of menstrual dysfunction in reproductive age group women suffering acute musculoskeletal trauma, 198 women between 15 and 50 years of age admitted consecutively into an acute orthopaedic unit were recruited over a 6-month period. The patients were then followed up for 6 months with menstrual diaries to compare their menstrual pattern with their preadmission status. Excluding those with significant menstrual problems before admission, the menstrual pattern remained normal in 135 (68%) (EM), while 12 (6%) developed polymenorrhoea (PM), and 51 (25%) had oligomenorrhoea or amenorrhoea (OAM) within the 6-month observation. The three groups did not differ in their mean age, body mass index, parity or age of menarche, but previous cycle lengths were shortest in the PM group (25.4 days, SD 7.64) (p<0.05) and history of amenorrhoea in the previous one year was most common in the OAM group (p<0.025). Univariate analysis showed the incidence of moderate to major trauma,operative treatment, longer operative time, general anaesthesia, blood transfusion and immobilisation were significantly higher in the PM and OAM groups compared to the unchanged group (p<0.05). A logistic regression model showed that general anaesthesia and longer surgical operations remained significantly related to the development of menstrual dysfunction. We conclude that the pattern of menstrual dysfunction after acute orthopaedic trauma appeared to be dictated by the woman's pre-existing menstrual characteristics and the stress of surgical treatment.

Adolescent↗
PubMed1999

The Lower Extremity Functional Scale (LEFS): scale development, measurement properties, and clinical application. North American Orthopaedic Rehabilitation Research Network.

BACKGROUND AND PURPOSE: The purpose of this study was to assess the reliability, construct validity, and sensitivity to change of the Lower Extremity Functional Scale (LEFS). SUBJECTS AND METHODS: The LEFS was administered to 107 patients with lower-extremity musculoskeletal dysfunction referred to 12 outpatient physical therapy clinics. METHODS: The LEFS was administered during the initial assessment, 24 to 48 hours following the initial assessment, and then at weekly intervals for 4 weeks. The SF-36 (acute version) was administered during the initial assessment and at weekly intervals. A type 2,1 intraclass correlation coefficient was used to estimate test-retest reliability. Pearson correlations and one-way analyses of variance were used to examine construct validity. Spearman rank-order correlation coefficients were used to examine the relationship between an independent prognostic rating of change for each patient and change in the LEFS and SF-36 scores. RESULTS: Test-retest reliability of the LEFS scores was excellent (R = .94 [95% lower limit confidence interval (CI) = .89]). Correlations between the LEFS and the SF-36 physical function subscale and physical component score were r=.80 (95% lower limit CI = .73) and r = .64 (95% lower limit CI = .54), respectively. There was a higher correlation between the prognostic rating of change and the LEFS than between the prognostic rating of change and the SF-36 physical function score. The potential error associated with a score on the LEFS at a given point in time is +/-5.3 scale points (90% CI), the minimal detectable change is 9 scale points (90% CI), and the minimal clinically important difference is 9 scale points (90% CI). CONCLUSION AND DISCUSSION: The LEFS is reliable, and construct validity was supported by comparison with the SF-36. The sensitivity to change of the LEFS was superior to that of the SF-36 in this population. The LEFS is efficient to administer and score and is applicable for research purposes and clinical decision making for individual patients.

Activities of Daily Living↗
PubMed2004

Talar neck fractures: results and outcomes.

BACKGROUND: Talar neck fractures occur infrequently and have been associated with high complication rates. The purposes of the present study were to evaluate the rates of early and late complications after operative treatment of talar neck fractures, to ascertain the effect of surgical delay on the development of osteonecrosis, and to determine the functional outcomes after operative treatment of such fractures. METHODS: We retrospectively reviewed the records of 100 patients with 102 fractures of the talar neck who had been managed at a level-1 trauma center. All fractures had been treated with open reduction and internal fixation. Sixty fractures were evaluated at an average of thirty-six months (range, twelve to seventy-four months) after surgery. Complications and secondary procedures were reviewed, and radiographic evidence of osteonecrosis and posttraumatic arthritis was evaluated. The Foot Function Index and Musculoskeletal Function Assessment questionnaires were administered. RESULTS: Radiographic evidence of osteonecrosis was seen in nineteen (49%) of the thirty-nine patients with complete radiographic data. However, seven (37%) of these nineteen patients demonstrated revascularization of the talar dome without collapse. Overall, osteonecrosis with collapse of the dome occurred in twelve (31%) of thirty-nine patients. Osteonecrosis was seen in association with nine (39%) of twenty-three Hawkins group-II fractures and nine (64%) of fourteen Hawkins group-III fractures. The mean time to fixation was 3.4 days for patients who had development of osteonecrosis, compared with 5.0 days for patients who did not have development of osteonecrosis. With the numbers available, no correlation could be identified between surgical delay and the development of osteonecrosis. Osteonecrosis was associated with comminution of the talar neck (p < 0.03) and open fracture (p < 0.05). Twenty-one (54%) of thirty-nine patients had development of posttraumatic arthritis, which was more common after comminuted fractures (p < 0.07) and open fractures (p = 0.09). Patients with comminuted fractures also had worse functional outcome scores. CONCLUSIONS: Fractures of the talar neck are associated with high rates of morbidity and complications. Although the numbers in the present series were small, no correlation was found between the timing of fixation and the development of osteonecrosis. Osteonecrosis was associated with talar neck comminution and open fractures, confirming that higher-energy injuries are associated with more complications and a worse prognosis. This finding was strengthened by the poor Foot Function Index and Musculoskeletal Function Assessment scores in these patients. We recommend urgent reduction of dislocations and treatment of open injuries. Proceeding with definitive rigid internal fixation of talar neck fractures after soft-tissue swelling has subsided may minimize soft-tissue complications.

Adolescent↗
PubMed2001

Incomplete lupus erythematosus: results of a multicentre study under the supervision of the EULAR Standing Committee on International Clinical Studies Including Therapeutic Trials (ESCISIT).

OBJECTIVE: Patients characterized with antinuclear antibodies (ANA) and disease symptoms related to one organ system can be described as having incomplete systemic lupus erythematosus (SLE). The aim of this multicentre study was to describe the outcome of these so-called incomplete SLE patients. Two aspects of the outcome were studied: (i) the disease course, defined by the presence or absence of clinical symptoms; and (ii) the number of patients that eventually developed full SLE. METHODS: Outcome parameters were the ACR criteria, the SLE disease Activity Index (SLEDAI), the European Consensus Lupus Activity Measure (ECLAM) and the requirement for treatment. In 10 European rheumatology centres, patients who had been evaluated in the last 3 months of 1994 and had been diagnosed as having incomplete SLE on clinical grounds for at least 1 yr were included in the study. All 122 patients who were included in the study were evaluated annually during 3 yr of follow-up. RESULTS: Our results are confined to a patient cohort defined by disease duration of at least 1 yr, being under clinical care at the different centres in Europe. These patients showed disease activity that was related mostly to symptoms of the skin and the musculoskeletal system, and leucocytopenia. During the follow-up, low doses of prednisolone were still being prescribed in 43% of the patients. On recruitment to the study, 22 of the 122 incomplete SLE patients already fulfilled the ACR criteria for the diagnosis of SLE. In the 3 yr of follow-up only three patients developed SLE. CONCLUSIONS: A high proportion of patients in our cohort defined on clinical grounds as having incomplete SLE eventually showed disease activity defined by the SLEDAI as well as ECLAM. However, only three cases developed to SLE during the follow-up. This suggests that incomplete SLE forms a subgroup of SLE that has a good prognosis.

Adolescent↗
PubMed2006

A neuro-mechanical transducer model for controlling joint rotations and limb movements.

Here we report on the development of an integrated general model for the control of limb movements. The model computes muscle forces and joint rotations as functions of activation signals from motoneuron pools. It models the relationship between neural signals, muscle forces and movement kinematics by taking into account how the discharge rates of motoneuron pools and the biomechanical characteristics of the musculoskeletal system affect the movement pattern that is produced. The lengths and inertial properties of limb segments, muscle attachment sites, the muscles' force-length, force-frequency and force-velocity (of contraction) relationships, as well as a load parameter that simulates the effect of body weight are considered. There are a large number of possible ways to generate a planned joint rotation with muscle activation. We approach this "overcompleteness problem" by considering each joint to be controlled by a single flexor/extensor muscle pair and that only one of the two muscles is activated at a given time. Using this assumption, we have developed an inverse model that provides discharge rates of motoneuron pools that can produce an intended angular change in each joint. We studied the sensitivity of this inverse model to the muscle force-length relationship and to limb posture. The model could compute possible firing rates of motoneuron pools that would produce joint angle changes observed in rats during walking. It could also compare motoneuron activity patterns received for two different hypothetical force-length relations and show how the motoneuron pool activity would change if joints would be more flexed or extended during the entire movement.

Biomechanical Phenomena↗
PubMed1999

Motivation for change in patients with prolonged musculoskeletal disorders: a qualitative two-year follow-up study.

BACKGROUND AND PURPOSE: The purpose of this study was to obtain a deeper understanding of the process of motivation for change in patients with prolonged musculoskeletal disorders and to identify factors that might influence change resulting in increased independence. METHOD: A qualitative two-year follow-up study. Data collection and analysis were performed according to the qualitative case study design. An initial conceptual framework was developed to bound and guide the study. Twenty patients were selected using purposive sampling with respect to motivation level (highly motivated to less-motivated) to create a sample of maximum variation. Data were collected using repeated interviews and standardized scales. The study comprised three data collection periods. RESULTS: Motivation for change followed different processes depending on the level at entry to the study. The highly motivated patients improved in independence, the moderately motivated ones remained at an unchanged level and the less-motivated patients became more dependent. Central themes of importance to the process of motivation for change were: the utilization of professional networks (healthcare, regional social insurance office), emotional support (nuclear family, close relatives), use of personal coping resources (energy, positive beliefs, problem-solving) and social support at work (employers, colleagues). CONCLUSIONS: The performance of a structured motivation analysis, including questions about emotional networks and social support at work in addition to the clinical examination of the patient, is recommended. This might guide healthcare professionals when it comes to motivation for change in the patient.

Adult↗
PubMed2006

[Future research needs and strategies for orofacial pain and oral motor disorders].

Musculoskeletal disorders in orofacial region are known to induce mastication disability and decrease the patients' quality of life levels. Additionally, the prevalence of those disorders tends to increase in elderly. However, since the existing therapies are not fully effective and medical expenses for those disorders are expanding, a prompt solution is necessary especially in aging societies like Japan. In addition, investigations for those disorders are important, because the research findings would be useful for the investigation of similar disease in other organs. Therefore, it is possible to consider that they can directly associate with general health and the universality of prosthodontics. In order to solve the above problems, two different research strategies are desirable. First, to improve the current curative effect, the effectiveness of existing diagnostic system and treatment modalities should be evaluated using high quality clinical studies. Second, as the research strategies on a long-term basis, investigations, which target the pathology and the contributing factors in a biological point of view are essential. This article will discuss about the research strategy to elucidate the pathology and the factors, which play important roles in the disease mechanisms, based on the previous and ongoing physiological research findings. Furthermore, I would like to review the useful newly developed technologies for the research strategy and new research fields, to enhance the value of prosthodontics and discuss about our future research direction.

Facial Pain↗
PubMed2001

Herbal therapy for treating rheumatoid arthritis.

BACKGROUND: The increasing popularity of the use of complementary and alternative interventions or treatments appears to be particularly evident amongst people with chronic disease. In the treatment of rheumatoid arthritis, one therapy that has been identified as having potential benefit, is herbal medicine (phytotherapy). OBJECTIVES: To assess the effectiveness of herbal therapies in the treatment of rheumatoid arthritis. SEARCH STRATEGY: We developed a search strategy using terms to include all forms of arthritis combined with herbal medicine. We searched the following electronic databases from 1966 to 2000: MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Cochrane Controlled Trials Register (CCTR), Cochrane Musculoskeletal specialized register, Dissertation Abstracts, BIDS ISI and the Cochrane Complementary Medicine Fields Specialized Register. This was supplemented by searching the reference lists from retrieved trials. SELECTION CRITERIA: All randomized trials of herbal interventions in rheumatoid arthritis, compared to placebo. Two reviewers independently read and selected each potential study according to the criteria published in an a priori protocol. Papers of any language were included. DATA COLLECTION AND ANALYSIS: Data were extracted independently by the same two reviewers and an assessment of methodological quality was conducted. MAIN RESULTS: Eleven studies met the inclusion criteria. Seven of the studies compared gamma-linolenic acid (GLA) to placebo although three of these were not suitable for data pooling. The remaining studies considered four different herbal interventions and were assessed individually. All of the GLA studies found some improvement in clinical outcomes but methodology and study quality was variable, making it difficult to draw conclusive results. However, the better quality studies suggest potential relief of pain, morning stiffness and joint tenderness. With the exception of one intervention (Tripterygium wilfordii hook F), no serious side effects were reported. REVIEWER'S CONCLUSIONS: There appears to be some potential benefit for the use of GLA in rheumatoid arthritis although further studies are required to establish optimum dosage and duration of treatment. The single studies are inconclusive.

Arthritis, Rheumatoid↗
PubMedDate not supplied

Characteristics of chiropractic practitioners, patients, and encounters in Massachusetts and Arizona.

OBJECTIVE: To describe chiropractic care using data collected at the time of each patient visit. METHODS: Random samples of chiropractors licensed in Arizona and Massachusetts were recruited to participate in interviews about their training, demographics, and practice characteristics. Interviewees were then recruited to record information about patient condition, evaluation, care, and visit disposition on 20 consecutive patient visits. RESULTS: Data for 2550 chiropractic patient visits were recorded. Care for low back, head and neck pain accounted for almost three quarters of visits. Extremity conditions and wellness care accounted for approximately half of the remaining visits. Spinal and soft tissue examinations were the most frequently reported diagnostic procedures (80% and 56% of visits, respectively), and high-velocity spinal manipulation techniques were the most frequently reported therapeutic procedures (almost 85% of visits). Rehabilitation exercises, thermal modalities, electric stimulation, and counseling/education/self-care were each performed during approximately 25% of visits. Approximately 85% of patients seen were self-referred, whereas only approximately 5% came from medical physicians. Approximately 35% of visits had an expected source of payment directly from the patient. Approximately 80% of visits ended with a plan for the patient to return at a specified time. CONCLUSION: These findings are consistent with the findings of previous studies and confirm that chiropractors use conventional patient assessment approaches with specific attention to spinal and musculoskeletal procedures, infrequently incorporating interventions commonly associated with other complimentary and alternative care providers. These findings illustrate that diagnostic assessment and follow-up are integral to chiropractic clinical encounters and offer a baseline for best practices development. The data also offer insight into chiropractic use and may be of interest to chiropractic leaders and education planners for professional development purposes.

Adult↗
PubMed2001

Ultrasound of the hand.

A recent development of high resolution transducers has increased the possibility to evaluate the most superficial body structures. The assessment of the normal anatomy and of the pathological changes of the hand and the wrist has become popular among musculoskeletal sonologists and nowadays ultrasound is considered one of the first line imaging techniques in the assessment of this district. Ultrasound must always be performed after a standard radiograph since the association of the two techniques can diagnose a wide variety of disorders. Some lesions however cannot be detected and require more invasive and expensive modalities (CT, MRI, CT and MRI arthrography). The goal of this article is to present the ultrasound appearance of inflammatory and traumatic diseases of the hand and wrist as well as the findings in entrapment neuropathies and soft tissue tumors.

Hand↗
PubMed2000

Safely directing patients to appropriate levels of care: guideline-driven triage in the emergency service.

STUDY OBJECTIVE: We sought to develop and validate standardized clinical criteria to identify patients presenting to the emergency department whose care may be safely deferred to a later date in a nonemergency setting. METHODS: Using a modified Delphi process, a 17-member multidisciplinary physician panel developed explicit, standardized, deferred-care criteria. In a prospective cohort design, emergency nurses at a tertiary care Veterans Administration (VA) Medical Center, using the criteria, screened 1,187 consecutive ambulatory adult patients presenting with abdominal pain, musculoskeletal symptoms, or respiratory infection symptoms. Patients meeting deferred-care criteria were offered the option of an appointment within 1 week in the ambulatory care clinic at the study site; all other patients were offered same-day care. As outcome measures, we assessed nonelective hospitalizations for related conditions occurring within 7 days of evaluation at our facility or any other VA facility within a 300-mile radius, and we assessed 30-day all-cause mortality. RESULTS: Two hundred twenty-six (19%) patients met screening criteria for deferred care. Patients meeting deferred-care criteria experienced zero (95% confidence interval, 0% to 1.2%) related nonelective VA hospitalizations within 7 days of evaluation, and none died within 30 days. By contrast, 68 (7%) of 961 (95% confidence interval, 5.5% to 8.9%) patients who did not meet deferred-care criteria were hospitalized nonelectively for related conditions, and 5 (0.5%) died. CONCLUSION: By using hospitalization and 30-day mortality as safety gauges, standardized clinical criteria can identify, at presentation, VA ED users who may be safely cared for at a later date in a nonemergency setting. These guidelines apply to a significant proportion of VA ED users with common ambulatory conditions. These criteria deserve testing in other ED settings.

Adult↗
PubMed2005

Intralesional curettage for grades II and III giant cell tumors of bone.

UNLABELLED: Grade III Campanacci lesions are traditionally treated with wide resections based on their postulated aggressiveness and potential for local recurrence and metastasis. The purpose of this study was to determine if there was a difference in local recurrence rates of Grade II and III lesions treated with intralesional curettage, burring, phenol cauterization, and polymethylmethacrylate application. Sixty-three patients (26 Campanacci Grade II and 37 Grade III lesions) met the inclusion criteria. No pathologic fractures, including intraarticular fractures, were included in this study. Followup averaged 108 months (range, 25-259 months). The overall local recurrence rate was 6% (4 of 63 patients), with no observed difference between Grade II and III lesions. The average Musculoskeletal Tumor Society functional score was 27.9/30 (93%). The mean range of motion of the adjacent joint was 97%. Patients with radiographic signs of osteoarthritis before treatment did not show substantial progression, and only one patient developed radiographic signs of degenerative arthritis postoperatively. Our distal metastatic rate was 3.2%. These data support the use of intralesional curettage and burring with adjuvant phenol and polymethylmethacrylate even in Grade III lesions, in the absence of pathologic fracture, regardless of the presence or extent of extraosseous extension. LEVEL OF EVIDENCE: Therapeutic study, Level III-1 (retrospective cohort). See the Guidelines for Authors for a complete description of levels of evidence.

Bone Neoplasms↗
PubMed2005

Exploration of work and health disparities among black women employed in poultry processing in the rural south.

We describe an ongoing collaboration that developed as academic investigators responded to a specific request from community members to document health effects on black women of employment in poultry-processing plants in rural North Carolina. Primary outcomes of interest are upper extremity musculoskeletal disorders and function as well as quality of life. Because of concerns of community women and the history of poor labor relations, we decided to conduct this longitudinal study in a manner that did not require involvement of the employer. To provide more detailed insights into the effects of this type of employment, the epidemiologic analyses are supplemented by ethnographic interviews. The resulting approach requires community collaboration. Community-based staff, as paid members of the research team, manage the local project office, recruit and retain participants, conduct interviews, coordinate physical assessments, and participate in outreach. Other community members assisted in the design of the data collection tools and the recruitment of longitudinal study participants and took part in the ethnographic component of the study. This presentation provides an example of one model through which academic researchers and community members can work together productively under challenging circumstances. Notable accomplishments include the recruitment and retention of a cohort of low-income rural black women, often considered hard to reach in research studies. This community-based project includes a number of elements associated with community-based participatory research.

Black or African American↗
PubMed2000

Arthur Steindler. Orthopaedic scholar, teacher, and clinician.

Arthur Steindler, a native of Austria, immigrated to the United States in 1907 and during the next 50 years he became very influential in the development of orthopaedics during the twentieth century. His life is a compelling example of how an individual can make major contributions to the advancement of medical science and practice. His clinical interests spanned the entire range of musculoskeletal disorders including developmental, genetic, infectious, neoplastic and neuromuscular diseases, and their operative and nonoperative treatment. He founded the clinical and academic Orthopaedic Surgery programs at the University of Iowa in Iowa City and directed their growth for 34 years. During that time his clinical work, scholarship, and teaching helped the University of Iowa become a national and international orthopaedic center. He helped establish a statewide system to provide medical care for indigent patients and personally treated more than 70,000 patients, many of them children crippled by polio, tuberculosis, spastic paralysis, scoliosis, congenital deformities, and degenerative neuromuscular diseases. To improve the function of the weakened and deformed limbs of the children, he devised various innovative operations. He wrote more than 130 papers and nine books in several languages on the natural history, etiology, and treatment of musculoskeletal diseases and injuries, pioneered the application of biomechanics to evaluation and treatment of musculoskeletal disorders, and wrote the first comprehensive text on the mechanics of human movement. He taught more than 300 orthopaedists, and when Ruth Jackson, the individual recognized as the first woman orthopaedic surgeon in the United States, decided to pursue a career in orthopaedics, she sought out Arthur Steindler and received her formal orthopaedic education under his direction. That Steindler accomplished so much after moving to the small midwestern town of Iowa City at the age of 37 is impressive, and clearly documents his remarkable abilities and determination.

Academic Medical Centers↗
PubMed2002

[Evaluation of computer-aided learning illustrated by the multimedia program, "Hereditary diseases of the dog--joints, bones, musculature"].

Results are presented on the evaluation of the interactive tutorial and information system "Hereditary diseases of the dog-joints, bones, musculature" which was developed at the Institute of Animal Breeding and Genetics and the Clinic for Small Animals at the School of Veterinary Medicine Hannover, aiming to improve the problem consciousness for the genetic background of most diseases of the musculoskeletal system of the dog. It addresses veterinarians, students of veterinary medicine and also dog breeders and owners. The programme offers extensive basic information about all known hereditary diseases of the joints, bones and muscles of the dog and gives also information on symptoms, diagnosis, therapy, distribution and genetics of the diseases. The user can apply it as a reference book, as a tutorial to complete or control his knowledge or to gain a fast overview of the up-to-date knowledge. The tutorial was evaluated by students in the second and third academic year, veterinary surgeons and dog breeders. Computer assisted learning was judged as very positive by all test persons. The programme received from all test persons an average score of 2.11 +/- 0.77 on a scale from 1 (very good) to 5 (unsatisfactory). The results show that computer-aided learning can be an effective and stimulating substitution to traditional learning and learning materials.

Animals↗
PubMed2003

Managing organ-threatening systemic lupus erythematosus.

Systemic lupus erythematosus is a chronic, usually life-long, and potentially fatal autoimmune musculoskeletal condition. The involvement of the heart, lungs, kidneys, and central nervous system, and hematologic complications increase morbidity and mortality. Consequently, the medical-surgical nurse must understand the disease process and treatment modalities when assessing and developing a plan of care for the patient and family.

Adolescent↗
PubMed2002

Alendronate as an effective countermeasure to disuse induced bone loss.

Microgravity, similar to disuse immobilization on earth, causes rapid bone loss. This loss is believed to be an adaptive response to the reduced musculoskeletal forces in space and occurs gradually enough that changes occurring during short duration space flight are not a concern. Bone loss, however, will be a major impediment for long duration missions if effective countermeasures are not developed and implemented. Bed rest is used to simulate the reduced mechanical forces in humans and was used to test the hypothesis that oral alendronate would reduce the effects of long duration (17 weeks) inactivity on bone. Eight male subjects were given daily oral doses of alendronate during 17 weeks of horizontal bed rest and compared with 13 male control subjects not given the drug. Efficacy was evaluated based on measurements of bone markers, calcium balance and bone density performed before, during and after the bed rest. The results show that oral alendronate attenuates most of the characteristic changes in bone that are associated with long duration bed rest and presumably space flight.

Journal Article↗