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Selected list of books and journals for the small medical library.

The interrelationship of print and electronic media in the hospital library and the relevance of the "Selected List" in 1985 are discussed in the introduction to this revised list of 583 books and 138 journals. The list is meant to be a selection guide for the small or medium-size library in a hospital or comparable medical facility, or a core collection for a consortium of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author/editor index and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by asterisks. To purchase the entire collection of books and to pay for 1985 subscriptions to all the journals would require about $45,200. The cost of only the asterisked items totals approximately $16,100.

Bibliographies as Topic↗

Expanded roles for hospital libraries: a direction for successful change.

Hospitals are changing to cope with a new environment and their libraries are changing with them. We demonstrate that hospital librarians can influence the change process and that expanding the role of the library is one option. Four case reports are presented to illustrate generic problems and how each library has coped with them. The issues facing hospital libraries today are viewed within the broader perspective of the American health care system.

Delivery of Health Care↗

The old library of the Pennsylvania Hospital.

The first medical book acquired by the Pennsylvania Hospital was William Lewis's Experimental History of the Materia Medica. Dr. John Fothergill of London donated it in 1762. The next year the Managers resolved to establish a library, and the physicians assigned their fees from hospital students for the purchase of books. Books were regularly ordered from William Strahan in London, and gifts and bequests added still more volumes. From 1790 to 1810 Dr. John Coakley Lettsom of London was the hospital's principal adviser on purchases. As the library grew, it expanded beyond purely medical works to include some in natural history, many purchased in 1817 from the estate of Dr. Benjamin Smith Barton. Catalogues were printed in the years 1790-94, 1806, 1829, and 1857. At midcentury the hospital library numbered about 9,000 volumes. At that time it was the largest medical library in the United States.

History, 18th Century↗

The history of medical libraries from 2000 B.C. to 1900 A.D.

Tablets said to date back to 2000 b.c. represent the earliest medical writings so far discovered. The history of the medical library (defined as a place where a collection of medical writings is kept) is traced through ancient and medieval civilizations, and the dependence of advancement or decline on the attitude toward learning and knowledge is demonstrated.The change in structure of medical libraries that took place around the 1500s with the development of scientific societies is discussed. Medical libraries of Colonial America are described and the history is brought forward to the era of public library collections of medical material in the early 1900s.

American Medical Association↗

Medical library development at the University of Ibadan, Nigeria.

While libraries of all kinds in Nigeria have many problems, some medical libraries are well established and are giving the services expected of such libraries anywhere. In current conditions of restricted finance and distance from metropolitan countries, consultation and cooperation in serials acquisitions together with union catalogs of serials would be of great value. Modern copying methods make this practical. Union catalogs of monographs would also be valuable. Two new major medical libraries are projected-one half-built, the other still at the planning stage. Each must be planned to give area services rather than purely local and internal services.

Libraries, Medical↗

New trends in medical libraries in hospitals.

External and internal forces affecting medical library services are examined. Public Law 89-239, the Heart, Cancer and Stroke Amendments of 1965, and Public Law 89-291, the Medical Library Assistance Act of 1965 which was extended by Public Law 91-212 have an impact on medical libraries. The Veterans Administration relationships with primary beneficiaries of these laws are explained. Internally, effort has been expended through automation, networking, and extension of resources by amalgamation of books and audiovisuals to evolve responsive concepts with emphasis on independence through interdependence. The Veterans Administration Library Service plans and accomplishments in these areas are reviewed.

Information Services↗

The Medical Library Center of New York: a progress report.

An article published in the Bulletin in 1963 outlined the proposed program of the Medical Library Center of New York. This progress report describes actual functions of the Center and attempts to evaluate them after four years of experience. Details of adapting a building intended for other use, financing this cooperative enterprise, applying standard library techniques and equipment to an atypical library, and acquiring materials that complement, rather than duplicate, the collections of member libraries are given. New services, not envisioned in detail in the initial program, but initiated during this period of operation, are mentioned. The report ends with a tentative look into the future.

Libraries, Medical↗

The relationships of medical libraries to Regional Medical Program planning.

The development of Regional Medical Program legislation is summarized and the activities of the new Division of Regional Medical Programs of the National Institutes of Health are described. The first grants for regional medical programs were activated 1 July 1966, and as of 30 June 1967, forty-nine had been awarded out of a possible total of fifty-five. The importance of excellent medical library facilities within each region, especially in all major teaching hospitals, with extensions down to the level of the community hospitals, was emphasized, and the concept of the community hospital as a learning center utilizing the most modern library concepts and teaching devices was commended. The Medical Library Association was asked whether training programs were being developed which would produce the numbers of personnel needed to staff the increased number of medical libraries of the future and whether new training programs were needed for service at the community hospital level.

Education, Continuing↗

The Pacific Northwest Regional Health Sciences Library: a centralized operation.

The Pacific Northwest Regional Health Sciences Library is described in relation to its health manpower and library population. Among the services which it provides are a document delivery service. A computer system provides a reporting system which analyzes trends in the borrowing pattern; these patterns are discussed, and some unusual features explained. Publicity campaigns have been conducted. The influence of a centralized library service on other libraries is discussed.

Alaska↗

Linking the physical past to the program future: new library addition at the Medical College of Georgia.

Planning the addition to an existing health sciences library building involved problems not normally encountered in planning a totally new structure. Some of the problems in combining the old and new buildings of the Medical College of Georgia Library and their resolution are discussed in this paper. Emphasized in particular is the relationship between institutional goals, library goals, and the library building.

Facility Design and Construction↗

Technology at Washington University School of Medicine Library: BACS, PHILSOM, and OCTANET.

A brief overview of the Bibliographic Access and Control System developed by the Washington University School of Medicine Library is presented. Because the system has been described in two previous reports, this paper focuses on its relationship to other automated programs (i.e., PHILSOM and OCTANET), education of users, evaluation of the system, and outreach to the medical center. In operation for more than two years, BACS represents the computerization of much of the managerial and operational functions of the library, and marks the completion of stage 1 of the three stages of library evolution described in the AAMC report Academic Information in the Academic Health Sciences Center: Roles for the Library in Information Management.

Computers↗

Regional Online Union Catalog of the Greater Midwest Regional Medical Library Network: development and operation.

The GMRMLN Online Catalog was developed as an easily accessible locator tool for monographs and audiovisuals held within the Greater Midwest Regional Medical Library Network. The catalog was generated from machine-readable records in MARC formats contributed by regional libraries. It was mounted by BRS as a private database and is fully free text searchable using BRS search. Each institutional file was merged and purged of duplicates to create a single entry for each title. The catalog features an online interlibrary loan system that automatically routes a request to the two nearest, smallest libraries that own the title. If the request is not filled within the region, the system automatically routes it to the National Library of Medicine without the need to rekeyboard data. The system collects management data on interlibrary loan processing. Funding for the catalog permitted a trial period of use with cost support. Data on system operation were gathered during this demonstration.

Catalogs, Union as Topic↗

Computer-assisted instruction in a health sciences library: an experimental project.

The Leon S. McGoogan Library of Medicine at the University of Nebraska received a grant from the University of Nebraska Computer Network to study management aspects of providing computer-assisted instruction (CAI) resources. The library wished to determine: (1) faculty and student receptiveness to CAI as a library resource and (2) user response to CAI library services. A user questionnaire was designed to ascertain the appropriateness of initial management decisions regarding CAI access. The methodology employed in implementing this pilot project, the results of the questionnaire, and the future of CAI at the University of Nebraska are addressed in this paper.

Computer-Assisted Instruction↗

Veterinary medical school libraries in the United States and Canada 1977/78.

Data on seven aspects of veterinary medical school libraries are presented and discussed: demographic data on the schools of veterinary medicine the libraries support, number of bound volumes held and number of serial titles received, audiovisual materials, staffing levels and salaries, materials budgets, physical size, and access to computerized bibliographic data bases. The great variability, especially in collection size, is stressed and attributed to such factors as size and programs of the veterinary school, age of the school and library, geographic location, accessibility of other libraries, administrative structure, and exchange programs.

Canada↗

International exchange of scientific literature by U.S. academic health sciences libraries: a literature review and survey of current activities.

This paper reports results of a literature review and survey of current international exchange activities in 124 academic health sciences libraries in the United States. It describes the extent to which those libraries engage in exchange programs, the kinds of material sent and received, and the common problems in establishing and maintaining exchange relationships. Preferences of the respondents for future exchange programs are identified and recommendations for enhancing their value are made. The work reported is being used by the Medical Library Association Ad Hoc Committee on the International Exchange and Redistribution of Library Materials to develop a more workable and effective mechanism for continuing the international exchange of scientific literature and for facilitating the dissemination of scientific information to national and international network users.

Academic Medical Centers↗

Selected list of books and journals for the small medical library.

This revised list of 539 books and 136 journals is intended as a selection guide for small or medium-sized hospital libraries or for small medical libraries in comparable health care facilities. It can also be used as a core list by consortia of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author index and the list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries, 137 books and 54 journals, are indicated by asterisks. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $30,000. The cost of only the asterisked items, which are recommended for first purchase, totals approximately $8,900.

Book Prices↗

New library buildings: Creighton University Bio-Information Center.

In May 1977 the newly constructed Creighton University Bio-Information Center, costing over $4 million and containing more than 57,000 square feet of space, officially began to provide services. This facility houses three educational support programs--the Health Sciences Library, the Learning Resources Center, and the Biomedical Communications Center--that primarily serve the University's health sciences schools of medicine, dentistry, pharmacy, nursing, and allied health, and the University's major teaching hospital, Saint Joseph Hospital. This article begins with a brief history of the development of the library and is chiefly concerned with the Health Sciences Library and the Learning Resources Center. Criteria formulated during the design phase of the Bio-Information Center are identified. A description of the center and its services, with an emphasis on the application of these criteria, is set forth. Finally, an assessment of the current increased utilization of library services and resources contained in the Bio-Information Center is presented.

Facility Design and Construction↗

Neutralizing murine monoclonal antibodies to human IL-5 isolated from hybridomas and a filamentous phage Fab display library.

Conventional hybridomas and combinatorial Ab libraries were used to develop neutralizing murine mAbs to human IL-5. Mice were immunized with rIL-5. Spleens from two mice were used to generate hybridomas. Spleens from an additional three mice were used to construct a combinatorial library. In both instances, Abs were identified and selected by ELISA using 96-well plates coated with rIL-5. These Abs were tested for the ability to block binding of iodinated rIL-5 to the alpha-chain of the human IL-5 receptor (IL-5R alpha) and to inhibit proliferation of IL-5-dependent cells. By hybridoma technology, 16 mAbs were obtained, 11 of which blocked binding to IL-5R alpha, including three that inhibited proliferation. Quantitative binding assays and sequence analysis revealed that these latter three mAbs were closely related. Combinatorial cloning and selection by phage display was used to isolate 24 bacterial colonies secreting Fabs that bound to 125I-rIL-5 and to rIL-5-coated plates. Sequencing of 10 of the Fabs indicated that four unique Abs were obtained, comprising one predominant VH paired with one of two different VL. The sequence of the Fabs was distinct from the sequences of the neutralizing mAbs. In contrast to the mAbs, none of the Fabs blocked binding of 125I-IL-5 to IL-5R alpha or neutralized the biologic activity of IL-5. The inability to identify neutralizing Fabs was shown not to result from their monovalency, because a Fab derived from one of the neutralizing mAbs, by cloning and expression of its Fd and kappa light chains, retained neutralizing activity. By chain shuffling, pairing of the Fd fragment of the heavy chain of one of the neutralizing mAbs (2B6), with the light chain library derived from the IL-5-immunized mice, neutralizing Fabs were obtained. These Fabs contained light chain sequences closely related to the original light chain of 2B6. Hence, chain shuffling allowed detection of a light chain sequence that was not evident upon two-chain combinatorial selection. The results reveal differences in the Abs obtained from a combinatorial library vs hybridomas and demonstrate how these approaches can be used in concert to select mAbs with neutralizing activity.

Amino Acid Sequence↗