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PubMed1995

Delayed effects of ethanol, caffeine and nicotine assessed by wheel-running and drinking in mice.

Effects of ethanol, caffeine and nicotine, pleasurable substances, on wheel-running and drinking in mice that were housed under a 12 : 12-hr light-dark schedule (lighting period ; 6 : 00-18 : 00) were investigated. All drug administrations were carried out at 11: 00, a mid-light period. Although ethanol (0.8-2.4 g/kg p.o.) scarcely changed both the wheel-running and drinking during the light period, it was followed by a strong suppression of both behaviors during the coming dark period (18 : 00-6 : 00). The same treatment with caffeine (1-10 mg/kg s.c.) produced significant increase in the drinking during the light period, but suppression of the wheel-running during the dark period. Nicotine (0.1-1 mg/kg s.c.) significantly suppressed the wheel-running, but not drinking, during the dark period. The coadministration of nicotine (0.1-1 mg/kg) with ethanol (2.4 g/kg) reduced the behavioral suppression during the dark period. Whereas nicotine (0.1-1 mg/kg) reduced the increased drinking during light period by caffeine (10 mg/kg), but enhanced the caffeine-induced behavioral suppression during the dark period. These results indicate that the administration of pleasurable substances in the mid-light period results in a delayed effect which is characterized by a suppression of either and/or both wheel-running and drinking during the coming dark period starting 7 hr after the administration, and that nicotine acts to antagonize the effect of ethanol, but contrally to enhance the effect of caffeine.

Animals↗
PubMed2001

Smoking and drinking habits among the JPHC study participants at baseline survey. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases.

Smoking and drinking habits at baseline survey among 110,896 male and female residents aged 40-69 are reported as part of an ongoing prospective population-based cohort in 11 geographically diverse health centers in Japan. The age-adjusted proportion of current and former smokers was 54.8% and 21.8% in males and 8.3% and 2.1% in females, respectively. Mean age at initiation of smoking in males and females was 20.6 and 27.8 years of age, respectively. In males, the age-adjusted proportion of those who drink almost daily was 49.1% and that of those who drink almost never was 19.7%, while in females, it was 5.9% and 71.6%, respectively. When compared by health center, the proportion of male current smokers was lower in Miyako and Ishikawa, both located in Okinawa Prefecture, while in females the proportion was higher in urban areas, such as Katsushika and Suita. The proportion of those who drink almost daily in males was higher in Yokote, Kashiwazaki, Katsushika and Suita, and lower in Ishikawa and Miyako, but in Ishikawa and Miyako, the proportion of those who drink at social events was higher. In females, the proportion of those who drink almost daily was higher in urban areas. There was substantial variation in the types of alcohol beverages consumed by males. In contrast, alcohol consumption in females comprised mainly beer.

Adult↗
PubMed2005

Smoking, alcohol drinking and esophageal cancer: findings from the JACC Study.

BACKGROUND: Using a large-scale cohort of about 110,000 people established in 45 areas throughout Japan from 1988 through 1990, the study attempted to uncover the joint effects of combined smoking and alcohol intake on esophageal cancer mortality. METHODS: A cohort established from 1988 through 1990 included 46,465 men and 64,327 women aged 40 years and older and younger than 80. The number of female smokers and drinkers was low, and women were excluded from the analysis for that reason. In addition, 308 people with histories of malignant neoplasm, and 3,579 with unclear smoking and drinking data were also excluded, resulting in 42,578 people available for analysis. A follow-up of these individuals was conducted until 1999. Cox proportional hazards model was used for the analysis. RESULTS: The joint effects of number of cigarettes and amount of alcohol consumed per day were compared with non-smokers and non-drinkers or those consuming less than one unit of alcohol per day. An increased synergistic esophageal cancer mortality risk (3.88) for both smoking and drinking was observed for those smoking 20 cigarettes or less per day and drinking one unit of alcohol or more but less than three units per day, with the risk rising (6.30) for those smoking at least 21 cigarettes and drinking at least three units of alcohol per day. Even in non-smokers with increased alcohol consumption, and in non-drinkers or those drinking at most one drink per day with increased smoking, no increased risk was observed. CONCLUSIONS: In this cohort study of a Japanese population, increased esophageal cancer mortality risk was observed only when both factors of alcohol and tobacco intake were present simultaneously.

Adult↗
PubMed2005

Smoking and drinking habits five years after baseline in the JACC study.

BACKGROUND: Observing longitudinal changes in smoking and drinking habits is important for evaluating the risk of incidence and death from cancer or other diseases in a cohort study. METHODS: Smoking and drinking habits at baseline and about five years later among 18,312 males and 28,338 females were obtained from the baseline and interim surveys in the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) sponsored by Monbusho (Ministry of Education, Science, Sports and Culture of Japan). Changes in smoking and drinking habits between the two surveys were observed. Odds ratios for quitting these habits at interim survey were estimated. RESULTS: Percentages of current smokers at baseline and interim surveys were 51.0% and 45.5% in males, and 5.2% and 4.8% in females, respectively. Percentages of current drinkers at baseline and interim surveys were 78.0% and 73.2% in males, and 29.5% and 23.5% in females, respectively. The number of cigarettes per day among male current smokers and the usual amount of alcohol consumed on each occasion among current drinkers decreased between the two surveys. Odds ratios for smoking cessation increased with age at baseline and decreased with the number of cigarettes per day at baseline. Odds ratios for drinking cessation increased with age at baseline and decreased with the usual amount of alcohol consumed on each occasion at baseline. CONCLUSION: The decrease in smoking and drinking habits was observed during the five-year follow-up period. Higher age and lower levels of exposure were associated with quitting smoking or drinking.

Adult↗
PubMed1995

Adolescent drinking and driving: etiology and interpretation.

In the adolescent population, drinking and driving is an important cause of injury, disability and premature death. A literature review of the demographics and etiology of drinking and drinking/driving reveals: 1) which subgroups of the adolescent population are more likely to drink and drink/drive; 2) where and why adolescents drink and drink/drive; 3) peer and family issues associated with adolescent drinking and drinking/driving; and 4) adolescent expectancies and perceived efficacies associated with drinking and drinking/driving. A discussion of the role of theory and the use of etiologic data in intervention research precedes an overview of several types of school-based alcohol-prevention programs and recommendations for more theory based interventions.

Accidents, Traffic↗
PubMedDate not supplied

Evidence for cohort or generational differences in the drinking behavior of older adults.

Data from a survey of 928 older Bostonians show that there is a negative correlation between age and alcohol consumption among older adults: i.e., "old-old" people- those who are seventy-five years old or older-are more likely to abstain and less likely to drink in any quantity than the "younger-old"-those age sixty-seventy-five years old. Since the study collected only cross-sectional data, it is not clear whether there are developmental trends in alcohol consumption-that people drink less as they grow older-or whether there are cohort or generational effects. However, several retrospective data suggest that there are cohort or generational patterns of drinking behavior by older adults. Very old respondents, who now drink less than their younger counterparts, report consistently different patterns of life-long drinking habits; they report different parental drinking habits, and they have consistently different attitudes toward the effects of alcohol consumption upon health. The survey provides no insight into the nature of the historical factors which account for the differences in alcohol use. However, Prohibition, Repeal, and the Depression are likely to have played important roles.

Age Factors↗
PubMed1995

Effects of normative feedback on consumption among heavy drinking college students.

College students, particularly those who drink heavily, tend to overestimate the prevalence of heavy drinking among their peers. A self-regulation model predicts that feedback of undesirable deviation from normative standards would result in correction of behavior toward perceived norms. From a screening of 568 college students, sixty-four heavy drinkers were identified and offered the opportunity to participate in a survey study of drinking. Of these, twenty-six accepted and returned questionnaires with detailed information regarding their drinking practices. These were randomized to receive or not receive, by return mail, personal feedback of their drinking relative to population norms. At an independent follow-up interview, feedback subjects showed greater reduction in weekly consumption and typical intoxication levels, relative to controls. This simple feedback intervention, requiring no personal contact, may be a cost-effective strategy for reducing risky drinking.

Adult↗
PubMed2002

Relation of drinking alcohol to atherosclerotic risk in type 2 diabetes.

OBJECTIVE: The effects of drinking alcohol on atherosclerotic risks were investigated in 194 type 2 diabetic patients to determine whether drinking alcohol influences risk of atherosclerosis in diabetic subjects. RESEARCH DESIGN AND METHODS: The subjects were divided by the degree of their average weekly alcohol consumption into three groups: nondrinkers, light drinkers (ethanol consumption <210 g/week), and heavy drinkers (ethanol consumption > or = 210 g/week). The degree of atherosclerotic progression was evaluated using aortic pulse wave velocity (a-PWV), and possible atherosclerotic risks were evaluated using known atherosclerotic risk factors. RESULTS: a-PWV was significantly lower in light drinkers than in nondrinkers and heavy drinkers, but there was no significant difference in a-PWV between nondrinkers and heavy drinkers. Systolic blood pressure, HDL cholesterol, and triglyceride levels were significantly higher in heavy drinkers than in nondrinkers and light drinkers, whereas there was no significant difference in these levels between nondrinkers and light drinkers. The mean levels of BMI and blood HbA(1c), uric acid, and fibrinogen were not different between the three groups. There were significant positive correlations of a-PWV with age and systolic blood pressure and weak but significant negative correlations of a-PWV with alcohol consumption and HDL cholesterol level. CONCLUSIONS: Light drinking, but not heavy drinking, has preventive effects on atherosclerosis in type 2 diabetic subjects. The known beneficial effects of drinking alcohol on blood lipids and fibrinogen may not be involved in the preventive effect of light drinking on atherosclerosis in diabetic subjects.

Aged↗
PubMed2000

Association between changes in eating and drinking behaviors and respiratory tract disease in newly arrived calves at a feedlot.

OBJECTIVE: To investigate eating and drinking behaviors and their association with bovine respiratory disease complex (BRDC) and to evaluate methods of diagnosing BRDC. ANIMALS: 170 newly arrived calves at a feedlot. PROCEDURE: Eating and drinking behaviors of calves were recorded at a feedlot. Calves with clinical signs of BRDC were removed from their pen and classified retrospectively as sick or not sick on the basis of results of physical and hematologic examinations. Pulmonary lesions of all calves were assessed at slaughter. RESULTS: Calves that were sick had significantly greater frequency and duration of drinking 4 to 5 days after arrival than calves that were not sick. Sick calves had significantly lower frequency and duration of eating and drinking 11 to 27 days after arrival but had significantly greater frequency of eating 28 to 57 days after arrival than calves that were not sick. Calves at slaughter that had a higher percentage of lung tissue with pneumonic lesions had significantly lower frequency and duration of eating 11 to 27 days after arrival but had significantly higher frequency and duration of eating 28 to 57 days after arrival. Agreement for calves being sick and having severe pulmonary lesions at slaughter was adequate. Agreement for calves being removed and having pulmonary lesions at slaughter was low. CONCLUSIONS AND CLINICAL RELEVANCE: Eating and drinking behaviors were associated with signs of BRDC, but there was not an obvious predictive association between signs of BRDC in calves and eating and drinking behaviors. Fair to poor agreement was observed between antemortem and postmortem disease classification.

Animal Husbandry↗
PubMed1989

Perceived problem-solving skills and drinking patterns among college students.

The cognitive social-learning-theory literature on alcohol abuse points to failure to generate appropriate alternative behaviors to drinking as a major predictor of relapse to drinking. Viewing drinking as a continuous variable, ranging from abstinence to abuse, it should be possible to demonstrate a relationship between problem-solving abilities and drinking patterns. The hypothesis that individuals' perceived problem-solving skills are related to their pattern of alcohol use was examined. It was expected that poorer perceived problem-solving skills would be related to maladaptive use of alcohol in response to problem situations. 192 students in Introductory Psychology at a midsized southern university participated. Each subject completed questionnaires assessing frequency and quantity of alcohol use, and stimuli associated with the onset of drinking. The Problem-solving Inventory was used to measure perceived problem-solving skills. Drinking pattern variables were formed by factor analysis. Canonical correlation analysis of the data supported the hypotheses. Students with lower confidence in problem-solving capabilities reported greater use of alcohol to cope with negative emotions and to escape from responsibilities than students with high confidence in their abilities. Amount of alcohol consumed was not related to problem-solving skills.

Adaptation, Psychological↗
PubMed1985

Feeding and drinking behavior of mares and foals with free access to pasture and water.

The feeding and drinking behavior of 11 mares and 15 foals living on pasture with free access to water was recorded during 2,340 15-min focal samples taken over 2 yr. Lactating mares on pasture spent about 70% of the day feeding. Foals began feeding on their first day of life. As they grew older, they spent progressively more time feeding, but still spent only 47 +/- 6% of the time feeding by 21 wk of age. Foals fed primarily during the early morning and evening. While grass formed the major proportion of the diet of both foals and mares, they also ate clay, humus, feces, bark, leaves and twigs. Almost all feeding by foals was done while their mothers were feeding. Movement to water sources was frequently, but not invariably, carried out by an entire herd. Frequency (P = .005) but not duration (P greater than .05) of drinking bouts by mares increased as the temperature increased. Frequency was greatest at 30 to 35 C, at which temperature mares drank once every 1.8 h. Frequency of drinking varied with the time of day (P less than .01), being rarest during the early morning (0500 to 0900 h eastern daylight time) and most frequent during the afternoon (1300 to 1700 h). Drinking by foals was very rare. The youngest age at which a foal was observed to drink was 3 wk, and 8 of 15 foals were never observed to drink before weaning.

Animals↗
PubMed2000

Work stressors, drinking with colleagues after work, and job satisfaction among white-collar workers in Japan.

Although previous studies have examined the buffering effects of social support and coping style on the relationship between stress and alcohol consumption, they have typically relied on analysis of variance (ANOVA) or regression analysis. In addition, few studies have examined the potential stress-buffering effects of drinking with coworkers after work on the relationship between job stress and job dissatisfaction. In the present study, using a signal detection analysis, we evaluated the interactions of drinking with coworkers after work and work-stressor variables among Japanese white-collar workers (n = 397) in 1997. The analysis was performed for two groups of subjects divided based on their status in the company. This was necessary because in Japan the obligations to drink socially increase with one's rising status in the company. In both the "staff members and lower-level managers" and "middle-level and higher-level managers' groups, an interaction between work-stressor variables and drinking variables was observed. The findings imply that drinking with coworkers after work ameliorated the sense of job dissatisfaction, but only among those subjects who already had lower levels of work stressors. For subjects with high levels of work stressors, attitudes toward drinking with coworkers were unrelated to job satisfaction levels.

Adult↗
PubMed1979

Parental and peer influences as correlates of problem drinking among high school students.

This study was concerned with the relative importance of parental, peer, and demographic variables in predicting problem drinking among young people. A survey of drinking and drinking problems was conducted among 1,439 students in two schools in Ontario. A Multiple Classification Analysis was employed to identify variables with a significant and unique predictive power. It was found that problem drinking is best predicted with situational factors and those directly connected with drinking. Parental and peer variables had little unique predictive power. Problem drinkers were more often male, had their first drinks away from home, and usually drank in cars.

Adolescent↗
PubMed1986

The impact of raising the minimum drinking age on driver fatalities.

Time series analysis was used to obtain statistical tests of the impact of raising the drinking age on monthly driver fatalities in Illinois, Michigan, and Massachusetts. A control series design permitted comparison between younger drivers (21 or less years) and older drivers (25 and older) within states where the minimum drinking age was raised. Since the two groups share the same driving conditions, it was important to demonstrate that any reduction in fatalities was limited to the young age group within which the drinking age change occurred. In addition, control states were selected to permit a comparison between driver fatalities of the young age group (21 or less) in states with the law change and young drivers in states without the law change. Significant immediate reductions in fatalities among 21 and younger drivers in Illinois and Michigan were observed after these states raised their minimum drinking age. No significant reductions in any control series were observed. A linear decrease in young driver fatalities was observed after the drinking age was raised in Massachusetts. There was also a significant linear decrease in young driver fatalities in the Connecticut control series, perhaps due to increasing awareness among young drivers of the dangers of drinking and driving.

Accidents, Traffic↗
PubMed1993

Drinking in the injury event: a comparison of emergency room populations in the United States, Mexico, and Spain.

Variables related to drinking in the injury event were compared among probability samples of emergency room patients in Contra Costa County, California (N = 1,001), Mexico City (N = 1,688) and Barcelona, Spain (N = 1,684). Drinking companions and places of drinking prior to injury, place of injury associated with drinking, amount of alcohol consumed, proximity of drinking with the injury event, perceived drunkenness at the time, and causal attribution of drinking with the event were all found to vary among the samples. The data suggest that the context in which alcohol is involved in the injury event is affected by the context in which alcohol is typically consumed in a culture and is important in analyzing alcohol's role in injury occurrence and situations which may be considered high-risk for alcohol-related injuries.

Adolescent↗
PubMed1994

Mexican farmworker women's perspectives on drinking in a migrant community.

Alcohol use in farmworker communities has not been investigated to any extent. The literature on alcohol consumption and farmworkers is virtually nonexistent. This case study provides information on drinking patterns and problems in a Mexican farmworker community in Northern California. The focus is on Mexican farmworker women's perspectives on drinking in a specific social context: A migrant farmworker housing center. Male responses are provided as a basis for comparison and contrast. The study examines issues related to driving under the influence, public versus private space, and the centrality of considerations regarding children/youth in setting acceptable parameters for drinking. Data collection consisted of observations and 29 interviews of men (13) and women (16) farmworkers over a 6-month period in 1991. We found that most of the women in the camp abstain from drinking. They define male drinking as a problem when 1) youth are allowed and encouraged to drink, 2) an increase of individuals driving under the influence in the housing center becomes evident, and 3) when drinkers serve as poor role models for youth.

Adolescent↗
PubMed1995

Social context and sensation seeking: gender differences in college student drinking motivations.

An anonymous questionnaire was administered to students at two universities. The questionnaire contained the Social Context of Drinking Scales, the Sensation Seeking Scale, and measures of alcohol use intensity, frequency of alcohol-impaired driving, as well as frequency of riding with an impaired driver. The results revealed significant gender differences in the social context of drinking as well as sensation seeking. High intensity drinkers of each gender were more likely to drink in a context of Social Facilitation and score higher on the sensation seeking subscale--Disinhibition. High intensity men drinkers were more likely to drink in a context of Sex Seeking, whereas high intensity women drinkers tended to drink in a context of Emotional Pain. In general, the Social Context of Drinking Scales were superior to the Sensation Seeking Scales at being able to discriminate high from low intensity drinkers. The implications for targeted prevention programs on college campuses are discussed.

Adolescent↗
PubMed1984

Ruminal bypass of drinking water in lactating cows.

Drinking water that does not equilibrate with ruminal fluid, i.e., bypasses the rumen, was studied qualitatively and quantitatively in eight rumen-fistulated lactating Holstein cows. Decreased temperatures in the sulcus omasi and abomasum shortly after initiation of drinking indicated that water had bypassed the rumen. Recovery of a water-soluble marker, included in drinking water offered after water was withheld for 4.5 or 9 h following feeding, was used to estimate ruminal bypass. For respective treatments, 18 and 5% of drinking water was calculated to have bypassed the rumen. Ruminal bypass in lactating cows drinking relatively large amounts of water could affect comparisons of water intake with total ruminal fluid outflow as measured by dilution of a water-soluble marker. Drinking water should not be assumed to equilibrate with ruminal fluid.

Abomasum↗