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The distribution of human motion detector properties in the monocular visual field.

The detection of coherent movement in stroboscopically (100 Hz) displayed moving random checkerboard ("Julesz-") patterns is studied psychophysically for eccentricities up to 48 degrees in the temporal visual field. Starting from the assumption that the studied visual subsystem consists of ensembles of 'bilocal' movement detectors ("Reichardt-detectors"), the parameters of these elementary detectors are deduced from the experimental results. This leads to the following interesting insights into the functional architecture of the system. At any eccentricity there is a critical velocity value Vc (near the center of the range of detectable velocities) at which both the spans and the delays reach their minimum value. Thus Vc can be defined as the ratio of the minimum span to the minimum delay values. At velocities below Vc the spans are constant and the delays are inversely proportional to V. At velocities above Vc the delays are constant and the spans increase proportional to V. The critical velocity Vc at any given eccentricity equals N times Vco, where Vco, is the critical velocity for foveal vision and N an eccentricity scaling factor. (N is the inverse normalized "cortical magnification factor"). Thus there is a complete structural invariance in terms of eccentricity-scaled units. Given the eccentricity scaling factor, the determination of two subject dependent constants of foveal vision, the minimum span and minimum delay, suffices to predict the main properties of the motion detection system at any eccentricity.

Female↗

Sampling systems for visual field assessment and computerised perimetry.

Three successive stages in the representations of the visual image are studied by computations from the best available data. The results are embodied in projections, drawn automatically. These projections are related to the assessment of visual disability and the dimensions of lesions in the retina and visual pathway. Fields can be assessed visually with the aid of graticules or directly during computerised perimetry.

Computers↗

[Computer perimetry of glaucomatous visual field defects at different stimulus sizes (author's transl)].

The influence of stimulus size in computer perimetry of central visual field defects was investigated in 30 glaucomatous eyes of 30 patients. 12 eyes had been studied utilizing stimulus size 1 and 3, 18 eyes with stimulus size 3 and 5 at the computer perimeter Octopus (program 31). Using large test targets small scotomata can be overlooked and identified field defects appear smaller and less deep. To evaluate this well-known phenomenon quantitatively by computerized perimetry was the aim of the present study. The mean threshold values in the diseased areas of the glaucomatous fields were about 6--10 db higher with stimulus size 3 than 1 and again 6--10 dB higher with stimulus 5 in comparison to 3. The clinical significance of these findings is discussed for different types of perimetry.

Computers↗

Sources of visual field interference in children and adults.

Subjects at three grade levels, third, sixth, and college (8, 11, and 20 years of age, respectively), were asked to identify briefly presented words accompanied by either words or letter strings in the same or opposite hemifield. Results indicated two sources of visual field interference, one relating to the presence of alphanumeric information elsewhere in the visual field and the second concerning the meaningfulness (lexical identity) of that information. The former showed a decrease in importance with age, and the latter an increase. Results were discussed in terms of the development of selective attention and hemispheric interaction.

Adult↗

Attention to one or two features in left or right visual field: a positron emission tomography study.

In human vision, two features of the same object can be identified concurrently without loss of accuracy. Performance declines, however, when the features belong to different objects in opposite visual fields. We hypothesized that different positron emission tomography activation patterns would reflect these behavioral results. We first delineated an attention network for single discriminations in left or right visual field and then compared this with the activation pattern when subjects divided attention over two features of a single object or over two objects in opposite hemifields. When subjects attended to a single feature, parietal, premotor, and anterior cingulate cortex were activated. These effects were strongest in the right hemisphere and were, remarkably, unaffected by the direction of attention. In contrast, direction of attention affected occipital and frontal activity: right occipital and left lateral frontal activity were higher with attention to the left, whereas right lateral frontal activity was higher with attention to the right. When subjects identified two features of the same object, parietal, premotor, and anterior cingulate activity was enhanced further, predominantly this time in the left hemisphere. Again, there was no direction sensitivity. Direction-sensitive activation of lateral frontal cortex also was increased. Finally, when subjects divided their attention over opposite hemifields, activity in the direction-sensitive occipital and frontal regions fell to a level midway between those seen during exclusively leftward or rightward attention. Thus, the behavioral efficiency with which we attend to multiple features of a single peripheral object is paralleled by enhanced activity in structures generally active during peripheral selective attention as well as in structures that depend on the specific direction of attention, most notably lateral frontal cortex. In addition, in the direction-sensitive regions, dividing attention over hemifields causes a compromise pattern between the extreme levels obtained during unilateral attention.

Adolescent↗

Steady-state visual evoked cortical potentials from stimulation of visual field quadrants. Optimizing pattern variables for the size of the field to be investigated.

The effects of check size and stimulus size were investigated to optimize the steady-state visual evoked cortical potentials from pattern-reversal stimulation of the visual field quadrants. Check sizes of 15', 30', 60', 90', 120' and 180' were investigated at a pattern reversal rate of 11.6 per second for field sizes varying from 2 degrees x 2 degrees to 24 degrees x 24 degrees. The visual evoked cortical potentials were recorded from mid occipital, right occipital and left occipital positions. In the inferonasal quadrant, the largest amplitudes were obtained with 30' and 60' check sizes; however, for these check sizes, the visual evoked cortical potential yielded limited additional information for field sizes greater than 4 degrees x 4 degrees and 6 degrees x 6 degrees, respectively. When a field size of 12 degrees x 12 degrees was investigated, a 90' check size was optimal. The results indicated that, with the above recording positions and check sizes of 15' to 120', there is an optimal number of pattern elements, 40 to 100, for stimulation of the inferonasal quadrant. This should be taken into account when a check size is selected to investigate a field quadrant of a particular size. Digital signal processing techniques were applied to analyze the visual evoked cortical potential, and the system shows promise for objective examination of the visual field.

Adult↗

The long-term fluctuation of the visual field in stable glaucoma.

PURPOSE: To determine, in stable glaucoma, the characteristics of the between-examination variability of the visual field recorded with the Humphrey Field Analyser (HFA; Humphrey Systems, Dublin, CA) using the homogeneous, LF(Ho), and heterogeneous, LF(He), components of the long-term fluctuation (LF), thereby providing a technique for separating progressive loss from fluctuation in sensitivity. METHODS: The LF components were calculated using a two-factor analysis of variance (ANOVA) with replications and were determined between each pair of three successive HFA program 30-2 fields for each patient from two groups, each containing 30 patients with primary open-angle glaucoma. The interval between examinations for the first group was 6 to 9 months and for the second group was 3 weeks. RESULTS: The group mean values for LF(Ho) ranged from 1.50 to 2.19 dB and for LF(He) from 1.70 to 2.05 dB. The average difference between examinations was within +/-0.35 dB for each component, and the 95% limits of agreement for the two groups, respectively, were +/- 2.31 and +/- 2.39 dB for the LF(Ho) and +/- 2.36 and +/- 2.09 dB for the LF(He). The estimate of the 90% confidence limit for the LF(Ho) was 3.30 dB and for the LF(He), 3.60 dB. Little relationship was present between the LF components and the modulus differences in mean deviation (MD), the corrected pattern SD (CPSD), or the mean MD, mean short-term fluctuation, and mean CPSD, of the two fields. CONCLUSIONS: Estimation of the LF components and of the corresponding confidence limits yields an expression of the normal between-examination variability of two consecutive fields that can be used as a reliability index. A value outside the confidence limits indicates the necessity for a confirmatory follow-up field.

Aged↗

[Sensitivity and specificity of the Heidelberg retinal tomograph for imaging nerve fiber bundle defects in glaucoma patients with localized visual field defects. Clinical study].

In order to verify whether nerve fiber bundle defects can be detected by the confocal technique of the Heidelberg Retina Tomograph (HRT), we compared the localization of localized visual field defects with the localization of the expected corresponding nerve fiber bundle defect. We examined 105 patients: 49 with primary open-angle glaucoma (POAG), 26 with low-tension glaucoma (LTG) and 10 with ocular hypertension (OH), and as a control-group 20 healthy eyes. The glaucoma stage had been defined by examination of the central visual field with the Octopus Perimeter 201 program 31 or 32 and/or the Humphrey Perimeter GG program. In healthy eyes, eyes with OH and POAG stage I (n = 19), no nerve fiber bundle defect could be found. In stage II (n = 15) and stage III (n = 14) we found nerve fiber bundle defects in all patients with POAG and LTG (except for one patient with POAG stage III). In stage IV (n = 27) no localized nerve fiber bundle defects were detected in eyes with POAG, but in 4 of 7 patients with LTG, defects could be seen. In glaucoma stages II and III, nerve fiber bundle defects can be detected with the HRT. The control group shows, that the appearance of a nerve fiber bundle defect is no artifact caused by the HRT. However, examination of eyes with OH and POAG stage I also shows that this method is not sensitive enough to be useful for early diagnosis of glaucoma. Nevertheless, it may be possible to develop the confocal HRT method further as a nerve-fiber diagnostic method for glaucoma.

Glaucoma↗

A comparison of the visual field restrictions with the M17 series protective mask and the MCU-2/P chemical-biological mask.

The U.S. Air Force and U.S. Navy recently adopted the MCU-2/P Chemical-Biological Mask to replace the M17 series of protective masks. Visual field plots were generated on a patient wearing each of these respirators. Although both resulted in a decrease of the visual fields, the magnitude of restrictions was far less with the MCU-2/P Chemical-Biological Mask.

Equipment Design↗

Color appearance in the entire visual field: color zone map based on the unique hue component.

To provide the fundamental data for a color zone map, the color appearances of nearly unique hue stimuli presented over the entire visual field were qualitatively and quantitatively evaluated by hue and saturation judgments, blackness evaluation, and categorical color naming. The hue of red and green stimuli shifts toward a unique yellow, while that of yellow and blue does not change with an increase in eccentricity. The saturation of all the stimuli falls with an increase in the eccentricity in all directions. On the basis of the unique hue component, color zone maps for red, dark yellow, yellow, green, and blue stimuli are drawn. All the color zone maps extend over a wider region in the temporal and lower directions than in the nasal and upper directions of the visual field. The results are compared with the color zones of previous studies. The relationship between the color zones and the color categorization, as well as the underlying mechanisms of reduced saturation and hue shift, is discussed.

Adult↗

Possible association between heavy computer users and glaucomatous visual field abnormalities: a cross sectional study in Japanese workers.

STUDY OBJECTIVE: To study the association between computer use and visual field abnormalities (VFA) and to assess whether heavy computer users have an increased risk of glaucoma. DESIGN: Cross sectional multicentre study. Subjects and observation procedures: A total of 10 202 randomly selected Japanese workers (mean (SD) age 43.2 (9.8) years) were screened for VFA using the frequency doubling technology perimetry (FDT-VFA), in addition to undergoing a general medical check up, and then ophthalmologically examined. Information about their computer use and refractive errors was obtained from a questionnaire and interview, respectively. MAIN RESULTS: As a result of FDT test, 522 and 8602 subjects were positive and negative for FDT-VFA, respectively. A significant (p = 0.004) interaction was found between computer use and refractive errors regarding the risk of FDT-VFA. In stratified analysis, heavy computer users with refractive errors showed a significant positive association with FDT-VFA (odds ratio (OR) = 1.74, 95% confidence interval (CI) 1.28 to 2.37), while those without refractive errors did not. Comparison of 165 subjects with an ophthalmological diagnosis of glaucoma and 2918 controls showed that the OR for glaucoma of heavy computer users with refractive errors was 1.82 (95% CI 1.06 to 3.12). Of 165 subjects with glaucoma, 141 had refractive errors, especially myopia (96.4%, 136 of 141). CONCLUSIONS: Although there are limitations to this study, such as its cross sectional design, heavy computer users with refractive errors seem to have an increased risk of FDT-VFA. Glaucoma might be involved in an underlying disease and myopia in a risk factor for FDT-VFA.

Adult↗

[Relationship between the nerve fiber layer defect and parafoveal visual field defects in glaucomatous eyes].

We evaluated the nerve fiber layer defect (NFLD) in glaucomatous eyes imaged by a scanning laser ophthalmoscope (SLO, Rodenstock Gm BH, Munich, Germany) and its relationship to parafoveal visual field defects. Twenty-three eyes of 20 patients with open angle glaucoma were studied. Only those eyes were used in which NFLD reaching the temporal raphe of the nerve fiber layer was observed by the SLO in either the superior or the inferior hemisphere. We defined three topographic parameters of the NFLD: 1. the angle (0, degree) generated by a line A passing through the foveal pit and the disc center, and a line through the disc center to the point of the NFLD at the disc edge and closest to line A, 2. the horizontal distance (D1, mm) along the temporal raphe between the foveal pit and the point of the NFLD nearest to the foveal pit, and 3. the vertical distance (D2, mm) between the foveal pit and the point of NFLD nearest to the foveal pit. We also defined the nearest defect location (in degrees from the fovea) as the stimulus point with sensitivity loss greater than 6 dB in the Humphrey visual field (program central 10-2). A highly significant correlation was observed between each of the three NFLD parameters and the nearest defect location (p < 0.001). The NFLD parameters we have newly defined here may be helpful for evaluating parafoveal visual functional damages in open angle glaucoma.

Female↗

Visual field structure in the Empress Leilia, Asterocampa leilia (Lepidoptera, Nymphalidae): dimensions and regional variation in acuity.

Male Empress Leilia butterflies ( Asterocampa leilia) use a sit-and-wait tactic to locate mates. To see how vision might influence male behavior, we studied the morphology, optics, and receptor physiology of their eyes and found the following. (1) Each eye's visual field is approximately hemispherical with at most a 10 degrees overlap in the fields of the eyes. There are no large sexual differences in visual field dimensions. (2) In both sexes, rhabdoms in the frontal and dorsal ommatidia are longer than those in other eye regions. (3) Interommatidial angles are smallest frontally and around the equator of the eye. Minimum interommatidial angles are 0.9-1 degrees in males and 1.3-1.4 degrees in females. (4) Acceptance angles of ommatidia closely match interommatidial angles in the frontal region of the eye. We conclude that vision in these butterflies is mostly monocular and that males have more acute vision than females, especially in the frontal region (large facets, small interommatidial angles, small acceptance angles, long rhabdoms, and a close match between interommatidial angles and acceptance angles). This study also suggests that perched males direct their most acute vision where females are likely to appear but show no eye modifications that appear clearly related to a mate-locating tactic.

Animals↗

[Changes in the visual field and dark adaptation following panretinal photocoagulation in diabetic retinopathy].

Within the past 5 years panretinal photocoagulation was performed in both eyes of 36 patients (Type I diabetics) with proliferative retinopathy. The age of these patients was between 21 and 38 years. The average follow-up period was 3.6 years. The effects on visual acuity, visual field, and dark adaptation were examined: in 65.3% of the cases (47 eyes) visual acuity remained unchanged; in 34.7% (25 eyes) central visual acuity was reduced. Depending on the coagulation technique and the number of coagulates applied, the visual field narrowed in a more or less pronounced way. Moreover, in all patients the dark adaptation threshold was elevated after panretinal photocoagulation.

Adult↗

Visual field x response hand interactions and level priming in the processing of laterally presented hierarchical stimuli.

Hemisphere-specific processing of laterally presented global and local stimulus levels was investigated by (a) examining interactions between the visual field of stimulus presentation and the response hand and (b) comparing intra- with inter-hemispheric effects of level priming (i.e. faster and more accurate performance when the target level repeats). Although in Experiment 1, which involved two-choice responses with left and right hands, performance costs occurred when the same hemisphere received the stimulus and controlled the response hand, further analyses suggest that these effects reflect spatial compatibility rather than intra-hemispheric interference. Consistent with the spatial compatibility interpretation, in Experiment 2 a similar visual field x response interaction was obtained with regard to left and right responses given with the same hand. Trial-to-trial level priming occurred in both experiments and was unaffected by the intra-hemispheric sequence of target levels. Implications regarding hemispheric processing mode are discussed.

Adult↗

Effects of betaxolol and flunarizine on visual fields and intraocular pressure in patients with migraine.

Fifty-one patients with migraine were divided into four groups to investigate the effects of topical betaxolol and systemic calcium channel blocker flunarizine on visual fields (VF) and intraocular pressure (IOP). The first group (Group 0) was followed with no medications, topical betaxolol (bid) was precribed to the second group (Group B), oral flunarizine (10 mg daily) was prescribed to the third group (Group F), and the last group (Group BF) was assigned for combined betaxolol and flunarizine treatment. After a mean follow-up time of 4.2 +/- 1.2 months (3-6 months), IOP measurements and VF tests were repeated. Group B and Group BF were found to be statistically different from the other groups in terms of IOP reduction and VF improvement according to mean deviation and corrected pattern standard deviation indices in the second examinations. On the other hand, Group F and Group BF differed from the other two groups considering the improvement in migrainous complaints. VF findings which are probably influenced by perfusion problems due to vasospastic mechanisms in migraineurs, improved following topical betaxolol treatment. However, systemic use of flunarizine--a calcium channel blocker--did not seem to be effective on visual fields although it had beneficial effects on migraine.

Adolescent↗

Neuropsychological impairment-associated visual field deficits in HIV infection. HNRC Group. HIV Neurobehavioral Research Center.

PURPOSE: To examine the relationship between loss in peripheral visual sensitivity and neuropsychological functioning in seropositive patients with human immunodeficiency virus (HIV) without infectious retinopathy. METHODS: Subjects carefully screened for retinal disease and well-matched across demographic and medical variables were grouped according to normal (perimetry-nl) versus abnormal (perimetry-abnl) performance on achromatic automated perimetry and short-wavelength automated perimetry, standard clinical ophthalmologic measures of visual function. All subjects completed a detailed neuropsychological test battery and were classified as impaired or unimpaired, globally and across eight neurocognitive domains. Subjects were also classified according to whether they met diagnostic criteria for minor cognitive/motor disorder (MCMD) or HIV-associated dementia (HAD). RESULTS: Visual field loss was associated with lower performance in the abstraction, perceptual-motor, learning, and motor domains. Significant group differences were also found on numerous individual neuropsychological tests. Based on clinical ratings, we found deficits in learning and motor functioning. No perimetry-nl subjects met criteria for MCMD or HAD, whereas 32% of perimetry-abnl subjects met diagnostic criteria for syndromic cognitive disorders (five MCMD and one HAD). In a subset of subjects who underwent a lumbar puncture, there was a trend for the perimetry-abnl group to have a higher concentration of beta2 microglobulin, a marker for central nervous system immune activation. CONCLUSIONS: These results suggest that in some HIV-infected people reduced visual function may be caused by nonretinal disease, and perimetry may present a sensitive measure of HIV-related brain dysfunction.

Adult↗