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Repair of late retinal detachment after successful treatment of retinoblastoma.

PURPOSE: To analyze the results of vitreous surgery for late retinal detachment (RD) after successful treatment of retinoblastoma. METHODS: The records of all patients with retinoblastoma seen at a single ocular oncology service between 1982 and 1998 were reviewed to identify patients treated for late RD. Previous treatments, characteristics of the RD, surgical techniques used, and visual and anatomic results of the surgery were recorded. RESULTS: Of more than 500 charts reviewed, four patients treated for late RD were identified. All four had received previous, whole-eye, external beam radiotherapy and subsequently required cataract surgery. Other previous treatments included radioactive plaque, cryotherapy, xenon photocoagulation, and chemotherapy. At presentation, some patients had shifting subretinal fluid. None had a tear identifiable preoperatively, but two patients had a definite small slit tear at a tumor edge identified at surgery. One patient had a primary scleral buckle that failed. All patients had vitreous surgery with silicone oil. Average postsurgical follow-up was 30 months. Preoperative visual acuity ranged from 20/80 to light perception and improved postoperatively in two patients. The retina remained completely attached in three patients. CONCLUSIONS: Despite shifting subretinal fluid and no identifiable tear, a rhegmatogenous RD should be considered if it occurs late in patients with otherwise stable, treated retinoblastoma. Tumor reactivation must be excluded carefully. Vitreous surgery can be used to repair the RD successfully and improve vision.

Child, Preschool↗

Rhegmatogenous retinal detachment after prophylactic argon laser photocoagulation.

In our hospital, 62 retinal detachments (RDs) in 58 patients who had previously been subjected to prophylactic argon laser photocoagulation (ALP), were operated on between July 1980 and October 1985. The incidence of RDs after prophylactic ALP has increased in recent years, being 3.90% (10 out of 256 RDs) in 1982, and 12.09% (26 out of 215 RDs) in 1985. The time interval between ALP and the occurrence of RD was less than 1 year in 54.7% of the patients, and between 1 and more than 10 years in 45.3%. Fifty per cent of the RDs developed after prophylactic ALP of retinal breaks. Fifty per cent of the RDs occurred after prophylactic treatment of degenerative lesions of the peripheral retina; 77% of the RDs in this last group occurred in eyes that had been subjected to 360 degrees photocoagulation. From the data obtained from the present series, the value of the 360 degrees technique for prophylactic ALP would appear to be rather questionable in most cases. In the present series, most RDs occurring after prophylactic ALP did not appear to be less severe than RDs in eyes that had not been subjected to prophylactic treatment.

Adolescent↗

Epidemiology of rhegmatogenous retinal detachment in a Finnish population.

During a -4 year period, 1978-1981, 310 eyes of 301 patients living in the district of the Helsinki University Central Hospital were examined for rhegmatogenous detachment of the retina. This corresponds to an annual incidence of 6.9 per 100 000 mean population. The mean age of the patients was 54.2 years, and the sex distribution corresponded with that in the general population. The right eye was significantly (P less than 0.05) more often affected than the left eye. 78% of the eyes were phakic, and 22% were aphakic. The corresponding annual incidences were 5.4 for phakic and 1.5 for aphakic detachment per 100 000 mean population. Myopia was found in 51% of the phakic and in 24% of the aphakic eyes. The estimated annual incidence of rhegmatogenous detachment in the myopic population was more than 3 times that in the non-myopic population. The annual incidence of traumatic rhegmatogenous retinal detachment was 0.8 per 100 000 mean population. There were significant (P less than 0.005) seasonal variations in the occurrence of retinal detachment.

Adult↗

Crohn's disease complicated by idiopathic central serous chorioretinopathy with bullous retinal detachment.

A case of idiopathic central serous chorioretinopathy with bullous retinal detachment occurring in a patient with Crohn's disease is described. This rare eye condition (36 reported cases in the world's literature) has previously been seen in association with ulcerative colitis, and its occurrence in a patient with Crohn's disease suggests that it may represent another ophthalmologic complication of inflammatory bowel disease.

Adult↗

The treatment of 4 cases of retinal detachment following insertion of an intraocular lens.

4 cases of retinal detachment following the use of an intraocular lens have been described. Each offered a different problem in management, the results being satisfactory in 3 out of 4 cases. The ability to dilate the pupil and the clarity of the media, along with the maintenance of the proper position of the lens seem to be the most important factors in the treatment of these cases.

Aged↗

[A roll of silicone sponge as an encircling element in the treatment of retinal detachment].

Presented are the results of treatment of more severe retinal detachments (82 eyes); in which a fragment or fragments of a silicone sponge roll encircled the eye ball performing a role of an extrascleral invaginating implant. The anatomical reattachment of the retina was achieved in 85% of cases (70 eyes). Misting of the vitreous (17%) was the more substantial early complications; it passed after a general application of antibiotics.

Adult↗

Silicone-oil injection during closed microsurgery for diabetic retinal detachment.

A beneficial visual outcome was achieved in 16 (38%) of 42 eyes into which silicone oil was injected after difficulties were encountered during closed microsurgery for severe diabetic retinal detachment. Without recourse to oil injection, most if not all of the eyes would have remained blind and many would have deteriorated into rubeotic glaucoma or phthisis. The main cause of failed surgery was rhegmatogenous retinal detachment associated with residual or reparative epiretinal fibrosis, and silicone oil appeared to be of value in preventing rubeosis iridis in such cases. Cataract was a significant problem in the successfully treated eyes.

Diabetic Retinopathy↗

Bare sclera closure in retinal detachment surgery.

Our modification of the limbal peritomy technique in retinal detachment surgery involved recession of the confunctiva 3 mm posterior to the corneoscleral limbus as the conjunctiva was closed. This recession offered some advantages over the standard nonrecessed method: fewer sutures were required; postoperative ophthalmoscopy was not impaired by conjunctiva swelling over the cornea; the eye was comfortable and quiet in appearance because there was no suture material or inflamed conjunctiva adjacent to the corneoscleral limbus. We have not encountered any disadvantages in several hundred cases.

Humans↗

The level of alpha-antitrypsin and ceruloplasmin in the subretinal fluid of patients with rhegmatogenous retinal detachment.

UNLABELLED: The aim of the study was to determine alpha-antitrypsin (AAT) and ceruloplasmin (CER) level in the subretinal fluid of patients with rhegmatogenous retinal detachment (RRD). Investigation was performed in 41 patients (22 women, 19 men) operated on for RRD at the age from 24 to 81. The group of patients was divided with regard to the extent and duration of RRD. In 24 patients detachment involved 1 or 2 quadrants and in 17 patients--3 or 4 quadrants. In 16 subjects RRD lasted shorter than 2 weeks, in 6 patients--about one month and in 19 patients--from 1 to 3 months. The subretinal fluid was collected during operation. The levels of the examined substances were determined with the radial diffusion method on Nor-Partigen plates by Behring. The results were as follows: mean AAT concentration in the subretinal fluid of all the patients operated on for RRD was 0.739 +/- 0.475 g/l and CER was 0.186 +/- 0.122 g/l. Mean AAT concentrations did not differ statistically significantly between the group with bigger and smaller retinal detachments while CER level was higher in the group with a bigger RRD. Mean AAT and the CER concentration was statistically significantly higher in the group with RRD lasting from 1 to 3 months compared with the group with RRD lasting shorter than one month. CONCLUSIONS: the fact of finding acute phase proteins in subretinal fluid suggests that they may play a part in the pathogenesis of RRD by affecting the intensity of local inflammatory reaction.

Acute-Phase Proteins↗

[Automobile driving capacity after retinal detachment surgery].

BACKGROUND: After vitreoretinal surgery the patient is at least temporarily unable to drive. Buckling procedures may cause refractive changes, reduced motility or impaired binocular vision. We examined the ability of these patients to drive a car according to German law after retinal surgery. PATIENTS AND METHODS: The frequency and extent of changes interfering with driving ability were examined in 112 unselected patients 3.5 years (2-5 years) after successful buckling procedures. We used half-round buckling elements of 3-11 mm diameter or encircling bands (2-3 mm). We examined visual acuity, frequency of permanent diplopia and field of normal binocular vision. Driving ability was considered as impaired, when visual acuity was below 0.4 in the better eye or 0.2 in the worse eye, or when diplopia occurred within a gazing field of 20 degrees of diameter. RESULTS: Eighteen of 112 (16%) patients reported diplopia within the first 3 months, so they were temporarily unable to drive. Two to five years later 14 of 112 patients did not have sufficient visual acuity according to the German requirements. Another 2 patients had an impaired binocular vision, resulting in driving disability. CONCLUSION: Driving ability may be temporarily restricted by double vision in 15% of patients after successful buckling for retinal detachment. Permanent driving ability is mainly impaired by macular involvement in retinal detachment. The type of buckling procedure is of minor importance.

Adult↗

The effect of prophylactic acetazolamide in patients undergoing extensive retinal detachment repair.

Encirclement of the eye as part of a retinal detachment repair is known to raise the post-operative intraocular pressure. We studied the effect of anticipating this pressure rise by giving perioperative acetazolamide to patients having vitrectomy and encirclement procedures. Two groups (9 with acetazolamide and 14 without) were matched for biographic variables, type of detachment and operation variables. The group given acetazolamide had lower day 1 post-operative intraocular pressures (mean 22.11 mmHg vs 36.36 mmHg, p = 0.002) and were able to go home sooner (mean 1.56 days vs 3.29 days, p = 0.001). No adverse effects of short-term acetazolamide use were noted in this study. We conclude that patients having extensive scleral buckling procedures should all receive prophylactic acetazolamide unless it is specifically contraindicated.

Acetazolamide↗

Temporary silicone oil tamponade in the treatment of complicated diabetic retinal detachments.

A retrospective study is reported on 132 eyes with retinal detachment, resulting from advanced proliferative diabetic retinopathy, treated using vitrectomy techniques and silicone oil tamponade. Epiretinal surgery was performed using a bimanual technique. Silicone oil was removed in 64 eyes (49%) which regained an improved final vision of 5/200 or better. In 17 eyes (13%), vision was improved but silicone oil could not be removed. It is expected that the function of several of these eyes will eventually deteriorate because of progressive silicone-induced glaucoma. The remaining 51 eyes (38%) were surgical and functional failures.

Diabetic Retinopathy↗

Epidemiological study of nontraumatic phakic rhegmatogenous retinal detachment.

We studied the epidemiological characteristics of nontraumatic phakic rhegmatogenous retinal detachment (RRD) in a defined population of Split-Dalmatia County, Croatia. A total of 278 eyes of 272 patients developed RRD during an 11-year period, 1988-1998, with a population of 465,947. The annual incidence was 5.4 per 100,000 population. The mean age of patients was 58.3 years, and the sex distribution corresponded with that in the general population. There was insignificant preponderance of right eye involvement. Bilaterality was observed in 2.2%. The presence of myopia was diagnosed in 46.9% eyes.

Adolescent↗

[Use of muscle surgery sutures in retinal detachment operations (author's transl)].

In cases of surgery in retinal detachment, borrowing of techniques employed in strabismus surgery is recommended. The opening of the conjunctiva and Tenon's capsule and careful placement of the final suture as published by Cüppers avoids or at least diminishes postoperative cicatrization, retraction, and resulting disturbances of motility and double images. In case where one are several muscles have to be cut, the exact strabismic muscle surgery helps this treatment. In these cases, statistical results are mentioned. Furthermore in cases of high myopia and especially those combined with nystagmus, the so called Cüpper's "Fadenoperation" gives excellent results. Three cases operated on by this technique, in which no other method succeeded, are demonstrated.

Cicatrix↗

Retinal detachment following Nd:YAG posterior capsulotomy.

Five hundred and eighty-two patients who underwent Nd:YAG laser posterior capsulotomy at Moorfields Eye Hospital were reviewed retrospectively. Twelve patients (2 per cent), nine of whom were previously myopic, subsequently developed rhegmatogenous retinal detachment. Comparison with other studies suggests there is no greater risk of retinal detachment associated with Nd:YAG laser capsulotomy than with surgical discission. The relevance of the damage mechanisms of Nd:YAG lasers are discussed.

Eye Diseases↗

Animal models of retinal detachment and reattachment: identifying cellular events that may affect visual recovery.

Retinal detachment continues to be a significant cause of visual impairment, either through the direct effects of macular detachment or through secondary complications such as subretinal fibrosis or proliferative vitreoretinopathy. Animal models can provide us with an understanding of the cellular mechanisms at work that account for the retinopathy induced by detachment and for the generation of secondary effects. As we understand the mechanisms involved, animal models can also provide us with opportunities to test therapeutic agents that may reduce the damaging effects of detachment or improve the outcome of reattachment surgery. They may also reveal information of use to understanding other causes of blindness rooted in retinal defects or injuries. Understanding the effects of detachment (and reattachment) are likely to become even more important as surgeons gain skills in subretinal surgical techniques and macular translocation, both of which will generate short-lived detachments. Here we discuss the fundamental events that occur after detachment, present changes associated with reattachment, and discuss retinal changes that may affect the return of vision.

Animals↗

[Retinal detachment after cataract surgery with intraocular lens implantation].

92 pseudophakic retinal detachments were treated in our hospital over a period of six years. These cases are reviewed retrospectively, with special emphasis on the factors that influenced the surgical outcome. The overall rate of success was 80%. Visual acuity was better than 0.1 in 77% of the cases. The major cause of failure was proliferative vitreoretinopathy, which was responsible for seven of ten failures. Postoperative proliferative vitreoretinopathy was the only factor that gave a significantly poorer prognosis after surgical treatment, although the presence of high myopia and preoperative proliferative vitreoretinopathy tended to give a less successful outcome. Likewise, there was a tendency for better prognosis in eyes with posterior chamber intraocular lenses.

Adult↗