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[Attempts at obtaining a pentavalent vaccine against leptospirosis].

Obtained was a five-valent vaccine (Leptospira pomona, L. canicola, L. grippotyphosa, L. mitis, and L. icterohaemorrhagiae). It was found that storage at 4degreesC does not impair the immunogenicity of the vaccine in the course of one year. Three groups of rabbits were used to test its immunogenicity--group I, injected once, subcutaneously, with 1 cu. cm of the vaccine; group II, injected subcutaneously, twice, at an interval of 7 days, with 1 cu. cm of the vaccine each time; and group III, injected once, muscularly, with 1 cu. cm. The animals were kept under observation for twelve months. It was established that in the case of intramuscular treatment there were highest antibody titers in the blood serum persisting up to the twelfth month.

Animals↗

[Serological study on bovine leptospirosis in Guadeloupe (author's transl)].

A serological study on bovines in Guadeloupe (French Carraibes) was conducted during 1973-1974. 456 animals were tested. Their sera were examined by microscopic agglutination technique with 20 antigens. Antibodies against the following serogroups: Ballum, Icterohaemorrhagiae, Bataviae, Australis, Pomona and Sejroë, were found. Ballum is the first serogroup by frequency and titers of antibodies. One young animal was ill and Immunological Test revealed a high titer of antibodies against serogroup Sejroë. This work demonstrates the existence of animal leptospiroses in Guadeloupe.

Animals↗

Serologic evidence of equine leptospirosis in the northeast United States.

Serologic testing for leptospiral antibody was conducted with the macroscopic agglutination test on 1,346 equine serum samples. These were collected from clinically normal horses in 123 purebred herds in the Northeast. Sixty-eight samples (5%) from the population tested reacted at significant levels (1:40 or higher) to one or more of the 5 serotype antigens used. These reactors were from 38 (31%) of the herds tested. Reactions to serotype pomona predominated in 25 (72%) of these 38 herds. Smaller numbers of herds had reactors to canicola, icterohemorrhagiae and grippotyphosa. No significant reactions to serotype hardjo were detected.

Animals↗

Painless pancreatitis: a rare manifestation of leptospirosis.

A rare case of painless pancreatitis caused by Leptospira is reported. The patient presented clinically with features of paralytic ileus and renal failure. Hyperamylasemia was persistent inspite of recovery of renal function. The patient recovered on treatment with penicillin and serum amylase returned to normal in three months.

Combined Modality Therapy↗

Leptospirosis.

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Anti-Bacterial Agents↗

[Leptospirosis].

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Animals↗