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The formation of explosive compounds in bitumen/nitrate mixtures

Ignition of various bitumen/nitrate mixtures was examined using a new method of thermal analysis, developed in the present study, in order to determine the self-ignition temperatures (SIT) of the sample materials. The effects on the SIT of transition elements, particularly silver, and the heating rates were examined. The same bitumen/nitrate mixtures were prepared by mixing bitumen, NaNO(3), Ni(NO(3))(2) and either AgNO(3) or AgI. The sample heating rates were in the range from 0.5 to 4.0 degrees C/min. In the present work, SIT was found to be independent on the heating rate when AgI is added, while SIT was found to depend on the heating rate when AgNO(3) was added. The activation energy E(a) for the ignition of bitumen/nitrate mixtures has been calculated to be 30 kJ/mol. The suspected initiator of the ignition is thought to be silver fulminates or related compounds.

Journal Article↗

Data explosion: the challenge of multidetector-row CT.

The development of multi detector-row CT has brought many exciting advancements to clinical CT scanning. While multi detector-row CT offers unparalleled speed of acquisition, spatial resolution, and anatomic coverage, a challenge presented by these advantages is the substantial increase on the number of reconstructed cross-sections that are rapidly created and in need of analysis. This manuscript discusses currently available alternative visualization tecvhniques for the assessment of volumetric data acquired with multi detector-row CT. Although the current capabilities of 3-D workstations offer many possibilities for alternative analysis of MCDT data, substantial improvements both in automated processing, processing speed and user interface will be necessary to realize the vision of replacing the primary analysis of transverse reconstruction's with alternative analyses. The direction that some of these future developments might take are discussed.

Angiography↗

Effects of the length ratio between the contractile element and the series elastic element on an explosive muscular performance.

Effects of the length ratio between the contractile element (CE) and the series elastic element (SEE) on the behavior of the muscle tendon complex were investigated during stretch-shortening cycles. A computer simulation model of the Hill-type muscle tendon complex was constructed. The proximal end of the CE was affixed to a point in the gravitational field, and a massless supporting object was affixed to the distal end of the SEE. A mass was held on the supporting object. Initially, the muscle tendon complex was fixed at a certain length, and the CE was activated at 100%. Through this process, the CE contracted as much as the SEE was stretched. Thereafter, the supporting object was released, which caused the muscle tendon complex to propel the mass upward, simulating a stretch-shortening cycle. The length ratio between the CE and the SEE, the size of the mass and the initial length of the CE were sequentially changed. As a result, it was found that a higher performance is obtained with a longer SEE when the mass is small, while with a shorter SEE when the mass is large.

Computer Simulation↗

New antiepileptic drugs--an explosion of activity.

The low therapeutic index of established antiepileptic drugs coupled with a better understanding of the pathophysiology of seizure production has led to the development of a range of new therapeutic agents for the treatment of epilepsy. In this review, the three drugs recently licensed in the UK (vigabatrin, lamotrigine and gabapentin) are profiled, together with several of the more promising up-and-coming compounds (oxcarbazepine, felbamate, tiagabine, stiripentol, remacemide and topiramate). Future avenues for clinical research in the pharmacological management of the epilepsies involve their rational use both singly and in combination.

Acetates↗

Developing explosive power: a comparison of technique and training.

The influence of contraction type and movement type on power output of the upper body musculature was investigated across loads of 30-80% 1RM. Twenty seven males (21.9+/-3.1 years, 89.0+/-12.5 kg, 86.32+/-13.66 kg 1RM) of an athletic background but with no weight training experience in the previous six months volunteered for the study. The results were compared using multivariate analysis of variance with repeated measures (p< or =0.05). It was found that the combinations of load, movement and contraction type affected mean and peak power in different capacities. Mean power output for rebound motion was 11.7% greater than concentric only motion. The effect of the rebound was to produce greater peak accelerations (38.5%--mean across loads), greater initial force and peak forces (14.1%--mean across loads) and early termination of the concentric phase. Peak power output was most influenced by the ability to release the bar, the greater mean velocities across all loads (4.4% average velocity and 6.7% peak velocity) attained using such a technique appeared the dominating influence. Loads of 50-70% 1RM were found to maximize mean and peak power. Loading the neuromuscular system to maximize mean or peak power output necessitates an understanding of the force-velocity characteristics of the training movement and the requirements of the individual related to the athletic performance and their training status.

Adult↗

A severe and explosive outbreak of hepatitis B in a rural population in Sirsa district, Haryana, India: unnecessary therapeutic injections were a major risk factor.

Most outbreaks of viral hepatitis in India are caused by hepatitis E. This report describes an outbreak of hepatitis B in a rural population in Haryana state in 1997. At least 54 cases of jaundice occurred in Dhottar village (population 3096) during a period of 8 months; 18 (33.3%) of them died. Virtually all fatal cases were adults and tested positive for HBsAg (other markers not done). About 88% (21/24) of surviving cases had acute or persistent HBV/HCV infections; 54% (13/24) had acute hepatitis B. Many other villages reported sporadic cases and deaths. Data were pooled from these villages for analysis of risk factors. Acute hepatitis B cases had received injections before illness more frequently (11/19) than those found negative for acute or persistent HBV/HCV infections (3/17) (P = 0.01). Although a few cases had other risk factors, these were equally prevalent in two groups. The results linked the outbreak to the use of unnecessary therapeutic injections.

Adolescent↗

Enhanced detection of nitroaromatic explosive vapors combining solid-phase extraction-air sampling, supercritical fluid extraction, and large-volume injection-GC.

A complete method for sampling and analyzing of energetic compounds in the atmosphere is described. The method consists of the hyphenation of several techniques: active air sampling using a solid-phase extraction cartridge to collect the analytes, extraction of the sorbed analytes by toluene/methyl tert-butyl ether modified supercritical fluid extraction (SFE), and analysis of the extract by large-volume injection GC-nitrogen/phosphorus detection. The GC system is equipped with a loop-type injection interface with an early solvent vapor exit, a utilizing concurrent solvent evaporation technique. Chemometric approaches, based on a Plackett-Burman screening design and a central composite design for response surface modeling, were used to determine the optimum SFE conditions. The relative standard deviations of the optimized method were determined to be 4.3 to 7.7%, giving raise to method detection limits ranging from 0.06 to 0.36 ng in the sampling cartridge, equivalent to 6.2-36.4 pg/L in the atmosphere, standard sampling volume 10 L. The analytical method was applied to characterize headspace composition above military grade trinitrotoluene (TNT). Results confirm that 2,4-dinitrotoluene (DNT) and 1,3-dinitrobenzene (DNB) constitute the largest vapor flux, but TNT, 2,6-DNT, and trinitrobenzene TNB were also consistently detected in all the samples.

Journal Article↗