[Dependence of perilymph's chemical properties upon electroacoumetry data of tinnitus aurium during otosclerosis].
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The use of lasers for primary and revision stapes surgery has many applications and potential advantages over mechanical techniques. It should be emphasized, however, that the laser is simply a tool, albeit a sophisticated one, and not a substitute for knowledge, experience, judgment, or ability. A laser will not "make" a good stapes surgeon, any more than a scalpel "makes" a good surgeon. There are limitations as well as benefits to lasers. Excellent results for stapes surgery were obtained for years prior to the advent of lasers, which is testimony to the skill and understanding of nonlaser stapes surgeons.
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The Authors report their personal data based on several studies carried out on cellular cultures of otosclerotic bones in order to clarify some pathogenetic aspects of the disease. Besides structural differences observed on the cytoskeleton, and some components of extracellular matrix (GAGs) of otosclerotic cells, the most interesting data arise from the different responses to hormonal stimulations using calcitonin, parathormone, steroid hormones and interleukin-1. This research leads the Authors to believe that transduction mechanisms in otosclerotic cells could be altered as a result of genetically induced receptorial changes, which become more evident after certain pathological events.
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