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PubMed1982

[Effects of veratridine on labyrinth receptors in the frog].

The action of the veratrum alkaloid veratridine has been tested on the sensory apparatus of the frog semicircular canals. Intracellular and extracellular recordings of the electrical responses evoked by sinusoidal mechanical stimulations of the ampullar organ could not reveal an action of the drug on the hair cells whereas the onset of the impulse discharge at the encoder of the afferent nerve fibres is largely facilitated by veratridine. The mechanism of the drug action is discussed.

Animals↗
PubMed1981

[Medullated ganglion cells in the guinea pig labyrinth].

The pericellular structures of the three ganglia situated in the petrous bone were investigated by light and electron microscopy in the guinea pig. All perikarya of the ganglion spirale cochleae and the ganglion vestibulare are surrounded by a myelin sheath which consists of 10-15 layers. Relative to their size, the cells of the ganglion spiral are characterized by a thicker myelin sheath than those of the ganglion vestibulare. The peripheral and central processes of the ganglion cells show a stronger myelination than the corresponding perikarya. The decrease in myelin from the nerve fibre to the perikarya does not proceed continuously but occurs only after the last interanular segment. At the peripheral processes, the myelin sheath ends a few micrometres before reaching the sensory epithelial layer. The perikarya of the ganglion geniculi nervi facialis are unmyelinated.

Animals↗