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Results for “ERYTHEMA”

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At least 1,711 records · Page 95Linked to original sources
PubMed1982

Suppressed natural killer cell activity during episodes of erythema nodosum leprosum in lepromatous leprosy.

Natural killer (NK) cell activity was investigated in peripheral blood mononuclear cells of patients with leprosy. The NK activity of patients with borderline or lepromatous leprosy did not differ significantly from that of normal subjects. However, in a group of patients with lepromatous leprosy undergoing an episode of erythema nodosum leprosum (ENL), NK activity was significantly depressed. In four patients with ENL, NK activity was virtually abolished. Depressed NK activity could not be attributed to the effects of corticosteroid therapy, nor did a serum factor appear to be responsible. Evidence was obtained that depressed NK activity in patients with ENL was not due to dysfunction of the NK cells themselves; they functioned normally when separated from the individual's total mononuclear cell population. Additional cell depletion studies suggested that the patients' monocytes were responsible for the observed depression of NK activity.

Erythema Nodosum↗
PubMed1981

[Erythema anulare centrifugum with pustulation. Successful oral retinoid therapy].

Erythema anulare centrifugum with pustulation (EACP) is an unusual sterile pustulosis, which is believed to represent a rare type of pustular psoriasis. HLA-examination in this patient did not show, however, the typical pattern of vulgar of pustular psoriasis. No other signs of psoriasis were found either, except for the spongiform pustule. The EACP most likely corresponds to a special entity in the large group of psoriatic skin diseases. Oral retinoid therapy revealed full remission of the skin lesions.

Erythema↗
PubMed1981

[Circumscribed reticular telangiectatic erythema following implantation of a heart pacemaker].

This is a short report of an erythema arising suddenly after implantation of a cardiac pacemaker on the right side of the thorax. The patient, the results of examination and histology, the thermophysiologic reactions are described and the diagnosis of cutaneous passive hyperemia offered, caused by the position of the pacemaker in connection with the multiple regional operation scars.

Erythema↗
PubMed1981

[An unusual case of erythema nodosum leprosum].

An unusual manifestation of erythema nodosum leprosum (ENL) in a female, 24 years old, whose clinical history and picture was suggestive of acute systemic erythematous lupus rather than hanseniasis is described and commented. The diagnosis of ENL was attained only after it was demonstrated the presence of AAR bacilli in the ulcerated lesions.

Adult↗
PubMed1980

Erythema multiforme -- an unusual reaction to BCG vaccination.

An eruptive form of erythema multiforme subsequent to BCG vaccination seen in a young Black nurse is reported. In a short review of the literature the author emphasizes that specific and nonspecific complications may occur after inoculation, but that the rare occurrence of these cutaneous manifestations cannot undermine the value of this preventive measure.

Adult↗
PubMed1980

[Rheumatic manifestations of erythema elevatum diutinum].

The authors report on a case of erythema elevatum diutinum developing at the same time as a seropositive rheumatoid polyarthritis. Disulone, moderately active on skin lesions, has little influence on the development of arthritis that have reacted well to treatment with D-penicillamine. A review of the literature makes it possible to identify the type of rheumatismal manifestations and immunological disorders accompanying the dermatosis. Three etiological circumstances must be looked for : focal infection, malignant lymphopathy, connectivitis.

Adult↗
PubMed1980

Erythema nodosum migrans in a young woman.

A case of erythema nodosum migrans in a 16-year-old girl is reported. We believe this to be the youngest patient described to date. The patient responded promptly to therapy with potassium iodide. The causes, pathogenesis, and treatment of the condition are discussed.

Adolescent↗
PubMed1980

Control of chronic erythema nodosum with naproxen.

A patient with chronic erythema nodosum of two years' duration, who did not respond to treatment with aspirin or with phenylbutazone therapy, had a dramatic response and improvement when treated with naproxen.

Adult↗
PubMed1980

[Alpha-tocopherol inhibition of erythema in skin photosensitized by 8-methoxypsoralen].

Irradiation of the rabbit and human skin by near UV light (wave lengths greater than 320 nm) in the presence of 8-methoxypsoralen produced erythema, pigmentation and some changes in the mechanical and electric properties. All the photobiological effects mentioned were inhibited by alpha-tocopherol if it was applied before irradiation. When applied after exposure to irradiation alpha-tocopherol appeared to be ineffective.

Animals↗
PubMed1980

[Erythema elevatum diutinum].

This 73-year-old lady presented since four years a clinically typical erythema elevatum diutinum. The disease responded very favourably to a treatment with chloroquine, whereas no improvement was obtained with dapsone.

Aged↗
PubMed1980

Erythema multiforme bullosum due to dapsone.

Two cases of tuberculoid leprosy who developed erythema multiforme bullosum (EMB) due to Dapsone (DDS) is reported. Burning and itching sensations were found to be the prominent prodromal symptoms. The patients gave history of urticaria and bronchial asthma. Salient clinical features and further management of the cases by desensitization with slow induction to DDS under cover of steroids and antihistamines have been discussed.

Adult↗
PubMed1980

Erythema chronicum migrans.

A patient with two episodes of an annular erythematous eruption is reported herein. Erythema chronicum migrans was suggested by the appearance and course of the eruption. In the second episode a bullous histology was found, possibly indicating an increasing hypersensitivity response. Since Weil-Felix titers did not change, there was a lack of correlation with rickettsia infection.

Arm↗
PubMed1981

Nitrofurantoin induced erythema nodosum.

The present case report clearly establishes nitrofurantoin as a cause for erythema nodosum (EN), presenting with serum sickness-like symptoms, typical and atypical EN skin lesions, and pseudo-splinter hemorrhages in a patient with documented mitral valve prolapse.

Erythema Nodosum↗
PubMed1978

Ossifying granulomatous periostitis in the course of erythema nodosum.

The author records a case of ossifying periostitis of the tibia apparently due to erythema nodosum. This does not appear to have been recorded previously. The histology, aetiology and differential diagnosis are discussed. The mechanism is probably one of direct spread from skin to periosteum.

Erythema Nodosum↗
PubMed1995

Electron microscopic observation of erythema nodosum with the eosinophilic infiltration. A case report.

The presence of eosinophils localized within an inflammatory skin lesion of a patient with erythema nodosum has been studied by electron microscopy. Among the intact eosinophils seen in the cellular infiltration, some underwent necrosis and released membrane-bound, free eosinophil granules into the interlobular septa of the subcutaneous fat. Such granules, identified by their central crystalline cores, often showed granular changes with core dissolution and were found scattered in the edematous space between the collagen bundles. A few intact eosinophils that showed minor alterations of cytoplasmic granules were also present. The significance of these findings, which may enhance endothelial permeability, is discussed.

Adult↗
PubMed1994

Attenuation of ultraviolet radiation-induced edema and erythema with topical calmodulin and protein kinase C inhibitors.

We treated Skh:HR1 hairless albino mice, NSA mice and hairless albino guinea pigs topically with N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) or trifluoperazine (TFP) before or after ultraviolet (UV) irradiation. When applied before irradiation, W7 and TFP prevented edema in Skh-1 mice and W7 prevented UV-induced edema in NSA mice in a dose-dependent manner. Preirradiation treatment with 2% W7 reduced erythema in guinea pigs by 50%. Epidermal histology of UVR-treated Skh-1 mice pretreated with W7 before UVR was similar to unirradiated mice. W7 did not reverse or prevent these UV-induced effects when applied after irradiation. Neither TFP nor W7 absorbed UV based on forward scattering absorbance spectra; we conclude that neither are physical or chemical sunscreens. These results suggest that calmodulin and/or protein kinase C-dependent events are involved in manifesting some of the effects of UV irradiation on skin.

Absorption↗
PubMed1995

Erythema multiforme with mucous membrane involvement and Stevens-Johnson syndrome are clinically different disorders with distinct causes.

BACKGROUND AND DESIGN: It was recently suggested that erythema multiforme (EM) majus and Stevens-Johnson syndrome (SJS) could be separated as two distinct clinical disorders with similar mucosal erosions but different patterns of cutaneous lesions. To test that hypothesis, we made a single-center retrospective study of severe EM with skin and mucosal involvement. Based on a review of clinical photographs, the skin lesions were reclassified as EM when these lesions were made of typical or raised atypical targets that were located on the extremities and/or the face, or as SJS when these lesions were made of flat atypical targets or purpuric maculae that were widespread or distributed on the trunk. Another investigator who was blinded for that clinical classification related each case to its more probable cause (eg, herpes infection or drug-induced reaction), by using scores derived from the medical charts. RESULTS: The majority (80%) of 76 cases could be classified as one of the two disorders: 28 as EM (37%), 33 as SJS (43%), and 15 as "undetermined" (20%). By using causal scores, the 76 cases were classified as herpes-induced (n = 18 [24%]), drug-induced (n = 40 [52%]), and "other" (n = 18 [24%]). There was a strong correlation between the clinical classification and the probable cause (K = 0.87, P < .001). Specifically, EM was mostly related to herpes (17 of 28 cases) or to other causes (eight of 28 cases); however, EM was rarely related to drugs (three of 28 cases), while SJS was nearly always related to drugs (28 of 33 cases) and never to herpes. CONCLUSIONS: The results of this study support the suggestion that EM with mucosal lesions and SJS could be distinguished on the basis of two different clinical patterns. In addition, a strong relationship was observed between each pattern and specific causes. This is one more piece of evidence that suggests that EM with mucosal lesions and SJS are actually two different diseases.

Adolescent↗