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[Dupuytren's contracture--late results of surgical treatment at a general surgery clinic].

In the years between 1982 and 1984 44 patients (39 men and 5 women) were operated on Dupuytren's contracture. More than 61% of the patients were treated in the stage II and III according to the classification of Iselin and Dieckmann. In these stages the total fasciectomy is the operation of choice. As operative approach we prefer skin incisions in the linea vitalis and linea mensalis. The recovery of the full function of the hand (especially the working capacity) was seen in 62.5% of the cases. Real relapses appeared in 8 cases. As most frequent postoperative complications appeared perception disorder, wound-healing impairment and edema/respectively haematoma.

Adult↗

[Cortical hyperostosis of the pisiform bone in stage I Dupuytren contracture in chronic alcoholics].

The author examined the carpalia of 40 male alcoholics suffering from Stage I of Dupuytren's contracture. In four subjects he observed a cortical hyperostosis of the right pisiform bone on the tangential films. The hyperostosis can be ascribed to the ethanol-induced hyperlipoproteinemia type II/B. The lipoids leaving the vascular paths infiltrate the connective tissue capsule of the pisiform bone and stimulate the formation of osteoblasts at the border between bone and soft tissue. The ossification must be regarded as enteropathic hyperostosis.

Adult↗

[Dupuytren contracture in childhood].

A two-year old boy suffered a contracture of the second and third digit beginning at the age of seven months. The clinical examination suggested a diagnosis of early Dupuytren's disease. A partial fasciectomy was performed. Histological examination showed a fibrosis palmaris similar to Dupuytren's disease. The biochemical examination (Glycans, hyaluronic acid, chrondroitinsulfat, dermatansulfat and heparansulfat) showed also changes in the extracellular proteoglycanmatrix similar to those found in adult Dupuytren's disease.

Child, Preschool↗

[Dupuytren's contracture. Radiotherapy in the early stages].

Conventional radiotherapy is the treatment of choice for the early stages of the Dupuytren contracture. The conventional semi-deep therapy is more favorable than the soft ray technique and the moulage technique. 62 patients have been treated at Erlangen; 33 out of them (46 irradiated hands) with a minimum observation time of 18 months have been evaluated. The pathologic process was stopped in 98% of the cases. 85% of the patients showed an improvement of troubles by regression of tubercules and cords, pains and sensation of pressure. A recurrence was observed only in one patient at the edge of the irradiated volume.

Adult↗

Joint contractures and acroosteolysis in Ehlers-Danlos syndrome type IV.

Among a series of 10 patients with Ehlers-Danlos syndrome Type IV, several had peripheral joint contractures and 3 had acroosteolysis. The consequent deformities simulated the appearance of chronic inflammatory joint disease and hence, patients with this rare syndrome may come to the attention of rheumatologists. Recognition of Ehlers-Danlos syndrome Type IV is important because of the risk of early death from arterial rupture. The syndrome is also of theoretical importance as an "experiment of nature" illustrating functional consequences of deficiency of Type III collagen.

Adolescent↗

Hip flexion contractures: a comparison of measurement methods.

Rater reliability characteristics of four positioning techniques used to measure hip extension (prone hip extension, Thomas, Mundale, and pelvifemoral angle) were compared. Two raters examined 45 children (90 hips), including patients with spastic diplegia and with meningomyelocele, who are prone to developing hip flexion contractures, and healthy subjects. Retests were performed on 21 children. The least reliable readings in the cerebral palsy group were found from tests using the Thomas technique, and in the meningomyelocele group using the Mundale technique. The pelvifemoral angle is more time consuming, and no more accurate than other methods. Considering the ease of measurement, reliability and reproducibility, we recommend use of the prone hip extension test for patients with cerebral palsy and for those with meningomyelocele, and recommend the Thomas test as an alternative for nonspastic patients.

Adolescent↗

Turnbuckle orthotic correction of elbow-flexion contractures after acute injuries.

Fifteen patients with acute flexion contractures of the elbow after injuries or operations were treated with a turnbuckle splint. Satisfactory correction was achieved in twelve patients. An average reduction in deformity of about 37 degrees was recorded after an average treatment period of twenty weeks. The treatment was unsuccessful in three patients with severe intra-articular damage because the splint caused excessive discomfort. The average improvement in the arc of motion of the elbow was approximately 43 degrees.

Adolescent↗

Dupuytren's contracture: fibroblast contraction? An ultrastructural study.

In 6 cases of Dupuytren's disease and 1 of Ledderhose's disease, the nodules of the palmar and plantar aponeurosis were examined by light and electron microscopy. The cells composing these nodules, presumably fibroblasts, showed three significant ultrastructural features: (1) a fibrillar system similar to that of smooth muscle cells; (2) nuclear deformations such as are found in contracted cells, the severest being recognizable by light microscopy (cross-banded nuclei); (3) cell-to-cell and cell-to-stroma attachments. Based on these data and on recent information about the biology of the fibroblasts, it is suggested that these cells are fibroblasts that have modulated into contractile cells (myofibroblasts), and that their contraction plays a role in the pathogenesis of the contracture observed clinically.

Adult↗

[Substantiation of the surgical approaches in Dupuytren's contracture and the technic of the operations].

The work substantiates the operative access in aponeurectomy for the Dupuytren's contracture realized by a wave-shaped incision in the zone of pathologically changed aponeurosis depending on the individual disposition of nodulous indurations and on a certain height of skin grafts in relation to the base. The operation technique is also described with special reference to possible errors resulting in serious sequelae. The complications observed are also described. Their number is less than that in the data of other papers which shows the positive result of the work as a whole.

Dupuytren Contracture↗

[The blood-flow in hands with Dupuytren's contracture and Raynaud disease: functional and morphological studies (author's transl)].

Concerning the question whether a correlation between the vasospasm and morphological changes in the neuro-myo-arterial glomerular (Hoyer-Grosser-Organ) exists also in Dupuytren disease, a series of 18 patients with Dupuytren and 5 patients with Raynaud disease were studied by finger venous occlusion plethysmography and finger tip biopsies. No typical histological changes were found in Dupuytren's Contracture, particularly none in the 13 cases (70%) which had a latent vasospasm and none in the 5 cases (30%) which had a normal plethysmogram, whereas in all the patients with Raynaud disease the typical morphological changes of wall, lumen and morphometric counts of the "Suquet-Hoyer" canals were found in correspondance to the abnormal plethysmogram. According to these results the vasospasm of Dupytren and Raynaud disease seems to be pathogenetically different.

Blood Circulation↗

Bipartite trapezium with adduction contracture of the thumb: a case report.

This is a case report on bipartite trapezium in a 12-year-old girl that presented as a painless protrusion at the base of the first metacarpal bone associated with an adduction contracture of the thumb. This seems to be the first such case to have been reported in an adolescent. The condition bears no resemblance to the numerous descriptions in the literature on accessory bones about the trapezium.

Child↗

Significance of histopathological findings in Dupuytren's contracture.

Clinical and histopathological data were compared in a series of 59 patients with Dupuytren's contracture (DC) from the years 1946-1971 in order to clarify whether histopathological findings were in accordance with the clinical development of the disease. All well known histopathological features were inspected. The most valuable prognostic sign seemed to be the appearance of several active nodules, indicating rather rapid development of DC, with a high frequency of postoperative recurrence in these patients. Lack of active nodules did not exclude this possibility but made it less likely. Other occasional findings typical of DC such as the number of mitoses, microhaemorrhages, perivascular lymphocytic infiltrations and hypertrophied corpuscles of Vater-Paccini seemed to be of minor prognostic value. Mucopolysaccharides from DC tissue showed metachromasia with toluidine blue did not stain with HID-AB (high iron diamine-alcian blue) as HID positive in specimens preserved embedded in paraffin blocks for several years.

Adult↗

Dupuytren's contracture--etiology and principles of treatment.

Although Dupuytren's contracture was first described more than 300 years ago, the cause is not yet certainly known. It is only agreed that the disease process affecting the palmar fascia is most commonly found in older-aged males of Caucasian descent. Conservative or non-surgical treatment is usually ineffective. Surgical treatment includes fasciotomy, partial fasciectomy and total fasciectomy. Fasciotomy is indicated for localized disease or for patients with medical conditions which preclude more extensive operation. Subtotal fasciectomy with or without skin graft is the most commonly employed procedure. Total palmar fasciectomy is seldom indicated. Improved function of the hand can be anticipated after adequate surgical intervention.

Dupuytren Contracture↗

[Neuropathy with contractures evoking the stiff-man syndrome. Latent solitary plasmacytoma].

A further case of apparently primary sensorimotor neuropathy is reported. The patient, a 31-year-old man, developed the syndrome after a 4-year history of a solitary vertebral plasmocytoma revealed by post mortem examination. Circulating monoclonal immunoglobulin and specific anomalies on nerve biopsy were absent. The condition became progressively worse, with initial and predominant autonomic nervous system anomalies. After 3 years, contractures of the limbs and paravertebral muscles, with painful paroxysmal attacks suggestive of the stiff-man syndrome appeared. Pathology confirmed the severity of the root lesions with diffusion to the cranial nerves. Reflex tests could not be conducted but the semiologic characteristics and the efficacity of baclofen were distinctive of continuous muscle fiber activities reported in some peripheral neuropathies. This case was comparable to some reported ones of interneuron rigidity.

Adult↗

[Dupuytren contracture in Mosel wine dressers with arsenic-induced aftereffect damage].

Between 1972 and 1981 a total of 121 male and female wine-dressers with late after-effects from arsenic were medically examined and treated. Skin and liver were examined regularly every 3 months. With advancing years an increase in typically arsenic melanosis, precancerous, carcinomas and hyperkeratosis in palmae and plantae was observed. A significant increase in Dupuytren's contracture was found in the age groups between 50 and 80 with a growing progression of typically arsenic horned pearls on the palms of the hands and soles of the feet. The typically arsenic horned pearls and arsenical keratosis occurred most frequently in the Dupuytrenical changes of the skin. The liver parameters showed no pathological results such as cirrhosis of the liver as compared with the other patients.

Arsenic↗