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PubMed2004

Correction of facial asymmetry with multiplanar mandible distraction: a one-year follow-up study.

OBJECTIVE: To assess the effectiveness of multiplanar mandibular distraction by evaluating the treatment effect and 1-year stability, measuring changes on the affected and nonaffected sides, and evaluating correction of the occlusal plane and oral commissure cant. PATIENTS AND METHOD: Eleven patients aged 5 to 9.4 years (mean 6.7 years ) who underwent unilateral multiplanar mandibular distraction were included, 10 with hemifacial microsomia and one temporomandibular joint ankylosis. Intermaxillary elastics were applied to intraoral dental devices during and after distraction until bony consolidation and occlusal interdigitation were achieved. Radiographs were taken and measured before distraction, after vertical distraction, after completion of distraction, and 1 year after treatment. Frontal facial photographs were obtained to analyze the changes in the position of the oral commissure. RESULTS: The facial profile was improved by sagittal mandibular advancement. Although the facial height increased 6.6 mm during vertical distraction, with a net gain of 5.8 mm in follow-up, the mandibular plane angle was maintained. The affected mandibular length increased 8.3 mm after distraction and remained unchanged after 1 year. Ramus height increased 12.7 mm after distraction and relapsed 3.8 mm at follow-up (30%). The affected body length demonstrated postoperative growth of 3.1 mm. Correction of the chin deviation was 9.8 mm after distraction and relapsed 1.6 mm (16.3%) after 1 year. Canting of the occlusal plane and oral commissure was corrected and remained stable. CONCLUSION: Multiplanar mandibular distraction is an effective treatment for correcting facial asymmetry in young children. The 1-year follow-up revealed that the new sagittal jaw relation and mandibular body length were stable, and the achieved occlusal interdigitation was well maintained. However, the ramus height and chin deviation demonstrated some relapse.

Cephalometry↗
PubMed2006

Technique and complications of callus distraction in the treatment of bone tumors.

INTRODUCTION: This study investigated the effects of chemotherapy, defect length, and patient age on the outcome and complications of callus distraction as a limb salvage technique in 17 patients. MATERIALS AND METHODS: The mean patient age was 18.4 years (range 7-47). Of 17 patients, 8 received chemotherapy and the remaining 9 patients did not. The mean defect length after excision of the lesion was 13 cm (range 8-20). The mean follow-up period for the patients whose treatments were completed was 55 months (range 20-90), the mean distraction index was 12.55 days/cm (range 11-15.7), and the mean external fixation index was 34.73 days/cm (range 30-41). RESULTS: In two patients, local recurrence occurred before distraction was completed. Two patients died, and one of them was a patient in whom local recurrence had occurred. Complications included non-union in one patient, osteomyelitis in one patient, and premature callus, osseous bridge, and varus of the femur in one patient. The extremity functional score was 80% (range 26-100). Chemotherapy and defect length had no significant effect on the distraction or external fixation indices. In contrast, the increase in the external fixation index in those over 20 years old was significant (P=0.043). CONCLUSION: We found that chemotherapy and defect length have no significant effect on the outcome and complications with this technique, which was more successful in patients younger than 20 years.

Adolescent↗
PubMed2004

Effective clinical outcome of a mandibular distraction device using three-dimensional CT with volume rendering in Pierre-Robin sequence.

Computed Tomography (CT) with three-dimensional reconstructions was studied in cranio-facial deformities. The pre-operative and follow-up study of cranio-facial deformities can be performed with spiral CT. With this modality quantitative information can be provided in order to measure the entity of airway obstruction and the result of procedure affecting bone structures.

Airway Obstruction↗
PubMed2006

Segmental alveolar distraction for the correction of unilateral open-bite caused by multiple ankylosed teeth: a case report.

Ankylosed teeth fail to erupt to meet their counterparts in the opposite jaw. In cases where ankylosis occurs in multiple teeth, the occlusion shows an open bite. This article describes a case of unilateral open bite caused by multiple ankylosed teeth, where treatment involved segmental alveolar bone distraction. A 25-year-old female patient presented with a left-sided unilateral open bite. On the left-hand side, only the lower incisors were not ankylosed. On the right, the maxillary first molar was ankylosed. All these ankylosed teeth were positioned below the occlusal plane. Her mother and brother also had multiple ankylosed teeth, and a familial cause was considered. Orthodontic tooth movement was considered impossible and segmental osteotomy on the left maxillary alveolar bone and downward bone distraction were performed as an alternative. A distractor consisting of orthodontic bands, wires and screws was devised and worn in the left mandibular dentition. Multi-bracket orthodontic appliances were also used for distraction. The amount of vertical movement was 7 mm at the premolar region. Five months after distraction, the multibracket appliance was removed, and fixed and removable retainers were placed. Eight months after distraction, prosthodontic restorations on the occlusal surfaces of the ankylosed teeth were made to obtain the final occlusion. The unilateral open bite was successfully treated and a good occlusion was obtained. The occlusion has shown good long-term stability for more than 3 years.

Adult↗
PubMed2000

Increased distraction rates influence precursor tissue composition without affecting bone regeneration.

The effect of increased distraction rate on bony tissue differentiation was studied using a paired bilateral model of rat femur lengthening. After a 6-day latency period, one randomly selected femur for each rat was distracted at 0.5 mm/day (normal rate) for 12 days, and the contralateral femur was distracted at 1.5 mm/day (increased rate) for 4 days. Femoral lengthening for each side was 6.0 mm, leaving the increased rate leg with an extra 8 days of consolidation compared with the normal rate limb. Group I rats (n = 9) were killed at day 18 postsurgery and analyzed for cartilage tissue composition and distribution. Group II rats (n = 7) were killed on day 36 postsurgery and analyzed by three-dimensional microcomputed tomography (MCT) for changes in new bone volume. Digital color analysis of slides stained with type II collagen antibody showed increases in cartilaginous tissue formation on the increased rate side (1.51 mm2 vs. 0.83 mm2; p = 0.10). No differences in new bone volume were detected between increased rate limbs and their contralateral controls (46.13 mm3 vs. 42.69 mm3; p = 0.63). These findings suggest that intermediate distraction rates may influence precursor tissue composition without affecting the final amount of new bone formed. Because damage to the tissue was not detected at either time point, these changes in chondrogenesis may reflect sensitivity of the pluripotential gap tissue to tension accumulation during lengthening. Future work with this in vivo model is focused on improving our understanding of the mechanisms behind this strain sensitivity.

Animals↗
PubMed2004

Assessment of bone formation in a porcine mandibular distraction wound by computed tomography.

The purpose of this study was to document the progression of bone formation in a porcine mandibular distraction wound, at various distraction rates and fixation times, using three-dimensional computed tomography. Bone formation was assessed in a 0-day latency model (n=24 minipigs) using distraction rates of 1, 2, or 4 mm/day to create a 12 mm distraction gap. Animals were sacrificed at 0, 8, 16, or 24 days fixation. For experimental and control sides, three-dimensional data from computed tomographic scans were used to calculate the percent bone volume in the regions of interest. Standardized plain radiographs were used to evaluate bone formation with a semiquantitative scale: 0, 1, 2, 3. Mean percent bone volume and radiographic bone fill scores (pooled sample) increased with fixation time from 16.8% and 0.17 at 0 days, to 64% and 2.0 at 24 days fixation. Mandibles distracted at 1mm/day had higher CT values and bone fill scores than mandibles distracted at 2 or 4 mm/day. At 24 days fixation, the maximum percent bone volume (64%--1 mm/day; 24 days fixation) remained below control values (81.3%). The results of this study indicate that despite high bone fill scores on plain radiographs, the highest percent CT bone volume achieved in this model was 64%.

Animals↗
PubMed2004

Horizontal alveolar distraction: a surgical technique with the transport segment pedicled to the mucoperiosteum.

PURPOSE: The study goal was to describe a surgical technique for performing horizontal alveolar distraction with the aim of increasing the width of alveolar ridges that are too narrow for dental implant placement. MATERIALS AND METHODS: A transport segment is cut from the vestibular side of the ridge, using osteotomes, and maintaining extensive attachment to the mucoperiosteum. The distraction screw is placed through the vestibular mucosa and the transport segment, in vestibular-palatal direction. Distraction is then performed to increase ridge width. RESULTS: We successfully applied this technique in a patient who required 2 dental implants at adjacent sites in the upper jaw but whose alveolar ridge was too narrow for direct implantation. With horizontal distraction, ridge width was successfully increased, allowing placement of the 2 implants (diameter, 3.3 and 4.1 mm). CONCLUSION: This technique shows promise for patients requiring implants in a narrow alveolar ridge. Depending on each patients specific requirements, we suggest that it be taken into account as a possible alternative to existing techniques.

Adult↗
PubMed2006

Relative ability of young and mature muscles to respond to limb lengthening.

The response of the muscle is critical in determining the functional outcome of limb lengthening. We hypothesised that muscle response would vary with age and therefore studied the response of the muscles during tibial lengthening in ten young and ten mature rabbits. A bromodeoxyuridine technique was used to identify the dividing cells. The young rabbits demonstrated a significantly greater proliferative response to the distraction stimulus than the mature ones. This was particularly pronounced at the myotendinous junction, but was also evident within the muscle belly. Younger muscle adapted better to lengthening, suggesting that in patients in whom a large degree of muscle lengthening is required it may be beneficial to carry out this procedure when they are young, in order to achieve the optimal functional result.

Aging↗
PubMedDate not supplied

Evaluation of distraction implants for prosthetic treatment after vertical alveolar ridge distraction: a clinical investigation.

PURPOSE: The purpose of this study was to clinically evaluate the mucosal condition and the esthetic and functional results of distraction implants loaded with fixed or removable implant-supported restorations. MATERIALS AND METHODS: A total of 35 patients were treated with 62 distraction implants for correction of alveolar ridge deficiency. The distraction implants were loaded with prosthetic superstructures 4 to 6 months after distraction. Nine patients were provided with single-crown restorations, 16 received metal-ceramic fixed partial dentures, and 10 received removable overdentures. Recall was scheduled before and 3, 6, and 9 months after implant loading. Periotest values, periimplant probing depths, and radiographic marginal bone levels were recorded, along with any biologic or mechanical complications. RESULTS: Patients were followed for 9 months after implant loading. Two distraction implants were lost before abutment connection. After fabrication and placement of individual abutments, all implants were loaded with prosthetic superstructures. The results showed a decrease of the Periotest values, and thus an increase of implant stability, during the following 9 months. Periimplant probing depths also decreased in the first months after implant loading. Soft tissue around the superstructures and adjacent teeth was healthy. CONCLUSION: The distraction implant system has a high potential for osseointegration. Because of the gentle distraction technique and the possibility of using individual abutments at almost any angulation, satisfying esthetic and functional results are possible. The rate of complications was low in this short-term study.

Adult↗
PubMed2004

Distraction lengthening of thumb metacarpal.

The purpose of this retrospective study was to evaluate the clinical outcome of distraction lengthening of the thumb metacarpal without bone grafting in seven patients with traumatic thumb loss. The distraction was stopped after 57 (range, 42 to 91) days, giving a median lengthening of 28 (range, 20-36)mm. It took an average of 155 (range, 118-196) days for bony consolidation to occur. The mean pinch power was 72% of that of the uninjured hand. The two-point discrimination on the pulp of the reconstructed thumb was 10 (range, 8-12)mm. There were no major complications.

Adult↗
PubMed2003

Alveolar distraction before insertion of dental implants in the posterior mandible.

We investigated the efficacy of alveolar distraction for reducing crown height:implant length ratio in the posterior mandible. Ten alveolar distractions were done in seven patients. The pre-distraction ratio of required crown height to bone height available for implantation was in all cases > or =1. Two implants were placed in each distracted area (total 20 implants). Before distraction, the mean (SD) predicted crown height was 12.8 (2.1) mm; mean bone height available for implantation was 7.8 (1.5) mm. After distraction and insertion of implants, mean crown height was 8.1 (1.9) mm, and mean implant length was 11.3 (1.9) mm. Before distraction, the mean required crown height:available bone height ratio was 1.7 (0.3); after distraction and insertion of implants, the mean crown:implant ratio was 0.7 (0.2) (P<0.0005). Alveolar distraction is effective for increasing the height of the alveolar ridge in the posterior mandibular region, and should be considered when the height of the predicted crown that is required is greater than or equal to the maximum height of bone available for implantation.

Adult↗
PubMed2001

The extracellular matrix of muscle--implications for manipulation of the craniofacial musculature.

Successful adaptation of craniofacial skeletal muscle is dependent upon the connective tissue component of the muscle. This is exemplified by procedures such as distraction histo/osteogenesis. The mechanisms underlying remodelling of intramuscular connective tissue are complex and multifactorial and involve extracellular matrix (ECM) molecules, receptors for the ECM (integrins) and enzymes that remodel the ECM (MMPs). This review discusses the current state of knowledge and clinical implications of connective tissue biology as applied to craniofacial skeletal muscle.

Adaptation, Physiological↗
PubMed2003

Segmental unilateral transpalatal distraction in cleft patients.

Patients with unilateral cleft lip and palate (UCLP) can present with an asymmetric transversal deficiency caused by collapse of the lateral maxillary segment at the cleft side. The surgical technique and orthodontic implications of segmental unilateral transpalatal distraction (TPD) after a posterior maxillary subapical osteotomy using the transpalatal distractor (TPD(R)) are described. The differences between unilateral posterior surgical-assisted rapid palatal expansion (SA-RPE) and segmental unilateral TPD are discussed. The proposed orthodontic-surgical treatment strategy certainly has to be validated by long-term studies in the future.

Cleft Lip↗
PubMed2005

Determination of ankle external fixation stiffness by expedited interactive finite element analysis.

Interactive finite element analysis holds the potential to quickly and accurately determine the mechanical stiffness of alternative external fixator frame configurations. Using as an example Ilizarov distraction of the ankle, a finite element model and graphical user interface were developed that provided rapid, construct-specific information on fixation rigidity. After input of specific construct variables, the finite element software determined the resulting tibial displacement for a given configuration in typically 15s. The formulation was employed to investigate constructs used to treat end-stage arthritis, both in a parametric series and for five specific clinical distraction cases. Parametric testing of 15 individual variables revealed that tibial half-pins were much more effective than transfixion wires in limiting axial tibial displacement. Factors most strongly contributing to stiffening the construct included placing the tibia closer to the fixator rings, and mounting the pins to the rings at the nearest circumferential location to the bone. Benchtop mechanical validation results differed inappreciably from the finite element computations.

Ankle↗
PubMed2003

Transversal palatal expansion using a palatal distractor.

METHOD AND RESULTS: The method and first results of transversal expansion with a palatal distractor in adolescents and adults with transverse maxillary deficiencies are presented. In ten patients with a mean age of 25.8 years, a newly developed distractor was applied for bone-borne expansion of the two halves of the maxilla following osteotomy of the lateral walls of the maxillary sinuses and the midpalatal suture. After a 3-week distraction period, mean changes of 8.8 mm in intercanine distance (ICD), 8.6 mm in anterior dental arch width (ADA), and 8.3 mm in posterior dental arch width (PDA) were registered. 6 months after the subsequent multibracket appliance therapy, these values were found to be largely constant. CONCLUSION: Because of the short treatment period, the absence of relapses, and the handling simplicity for the patient, this method is recommended for clinical application.

Adolescent↗
PubMed2006

A 2-stage procedure combining maxillary advancement by distraction technique with mandibular setback surgery in patients with cleft lip and palate.

A 2-stage procedure combining maxillary advancement by distraction technique with mandibular setback surgery was used to correct jaw deformities in 5 patients with severe maxillary retrusion secondary to cleft lip and palate. First, a Le Fort I maxillary osteotomy was performed. Immediately after maxillary distraction, the distraction device was removed. The advanced maxilla was fixed with miniplates after adjusting the length and direction of advancement, and mandibular setback surgery was performed simultaneously to obtain a normal occlusal relationship. This 2-stage procedure resulted in stable occlusion and a markedly improved facial profile.

Adolescent↗
PubMed2006

Rational treatment for multiple digit congenital absence: case report of nonvascularized toe phalangeal transfers and distraction lengthening for symbrachydactyly.

A case is discussed in which a young male was born with symbrachydactyly of multiple digits in whom nonvascularized proximal toe phalanges were transferred to the aphalangic digits when he was an infant. This initial surgical procedure was later followed by webspace deepening and ultimately by distraction lengthening of the digits. At 8 years of age, he has a very functional hand with mobile metacarpophalangeal joints in all reconstructed fingers. In fact, he uses this reconstructed right hand as his dominant extremity. The case is discussed in context of phalangeal growth potential, specific indications for this type of reconstruction, and final long-term outcome. This case also helps to recommend rational treatment protocols for similar congenital hand anomalies.

Bone Transplantation↗
PubMed2005

[Elimination of mandibular defects with dosed distraction. Part III. Use of dosed distraction for restricted osteoplasty in subtotal and end defects of the mandible].

Two variants (3(rd) and 4(th)) of non-free mandible osteoplasty with the use of compression-distraction apparatus (CDA) elaborated during the war in Afghanistan are described by the author. The 3(rd) variant was used in cases of vast combined defects of lower part of the face when two-sided osteotomy of both mandible stumps in order to create mobile mandible fragments of the length of 2.5 cm and their follow-up shift to the middle line of the face with the help of CDA is made. Distraction of callosity and soft tissues stimulated histogenesis that led to substitution of big osseous-soft tissue defect of lower part of the face. The 4(th) variant had two stages: 1(st) stage resulted in reconstruction of mandible branch, the 2(nd) -- in reconstruction of mandible head. In such a way the new temporomandibular joint using own tissues of the patient was created without application of allotransplant or titanium explant.

Afghanistan↗