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[Changes of mitochondrial calcium, adenosine triphosphate and adenosine diphosphate contents induced by occlusal trauma in rabbit's masseter muscles].

OBJECTIVE: To study the role of Ca2+ overload and energy metabolism in mitochondria in masticatory muscle dysfunctional induced by occlusal trauma. METHODS: Mitochondrial Ca2+ contents were measured with atomic emission spectrophotometer. Mitochondrial ATP and ADP contents were measured with high performance liquid chromatography. RESULTS: (1) Mitochondrial Ca2+ contents of masseter muscle ipsilateral to metal splint in ten and twenty days' experimental groups and that contralateral to metal splint in twenty days' experimental group increased significantly (P < 0.05). (2) Mitochondrial ATP contents of masseter muscle ipsilateral to metal splint in experimental groups were higher than that in control groups and contralateral to metal splint after twenty days. (3) Mitochondrial Ca2+ contents of masseter muscle ipsilateral to metal splint were significantly negatively correlated to the mitochondrial ATP contents (r = -0.780, P < 0.05). CONCLUSION: Ca2+ overload in mitochondria depresses ATP production, which results in energy metabolism disorder in masticatory muscle cells. It may play an important role in the mechanism that occlusal trauma results in masticatory muscle dysfunction.

Adenosine Diphosphate↗

Lateral displacement of the mandible in Rhesus monkeys.

Lateral displacement of the mandible was induced experimentally in five adult male Rhesus monkeys. Following from 2 1/2 weeks to 19 months, the animals were sacrificed and examined histologically. Two of the monkeys received H3 proline 4 months prior to sacrifice and radioautographs were prepared. The lateral displacement apparently caused great discomfort because the monkeys refused to eat and lost weight rapidly for a few months. After about 12 months, the monkeys could again eat their normal diet to the extent they started to gain weight slowly. The histological and radio-autographic findings indicated almost no changes of the articular surfaces of the temporomandibular joints. However, extensive reorganization of the neck of the condyles was observed. Severe periodontal trauma and extensive movements of the teeth occurred in spite of the fact that the teeth in each jaw were splinted firmly together.

Adaptation, Physiological↗

[Kinetics of supporting teeth in patients with partial dentures].

In 2 female patients with partial prostheses in the lower jaw, a pilot study was undertaken by means of inductive distance measures into the kinetics of supporting teeth during blank mastication over a period of 10 weeks. 1. Already at the beginning the end supports show unphysiological characteristics of movement during pressing and rubbing. 2. The existing canine guidance shows no abnormal kinetics of the supporting teeth during the excursions. 3. The direction of the kinetics of the supporting teeth changes in embedded part prostheses. 4. The abutment teeth show higher kinetic values after 10 weeks (without embedded partial prosthesis) than in the beginning. 5. In embedded partial prostheses all kinetic values closely approach the physiological norm. The directions on the other hand do not correspond with the physiological norm. The partial prosthesis acts as a splint for the abutment teeth.

Adult↗

Interactive imaging for implant planning, placement, and prosthesis construction.

PURPOSE: This review describes a new interactive imaging program that allows computed tomography (CT) images to be used to virtually place dental implants and construct a precise guide splint and final prosthesis for delivery at the time of implant placement. MATERIALS AND METHODS: Patients with edentulous arches were recruited to participate in a trial program to assess the feasibility of using CT images in a 3-dimensional image-based program (Oralim; Medicine NV, Belgium) for planning and placing dental implants. Patients meeting the criteria received a CT of the appropriate arch using a denture with radiopaque markers indexed to the opposing arch. Acquisition slices of 0.6 mm or less was required. The software allowed precise planning for implant placement after which the planned case was sent to a manufacturing facility for splint and prosthesis construction. RESULTS: The guide splint and final prosthesis were returned to the clinical site for implant placement. An implant map was provided for each patient showing the diameter and length of the implant and abutments to be used in each predetermined implant site. The surgery was accomplished without a flap, and the prosthesis was delivered immediately. Occlusion required only minor adjustments in all cases, and immediate function was accomplished. CONCLUSION: Interactive computer imaging can allow precise planning for implant position and the images can be used for guide splint and final prosthetic fabrication prior to surgery. This technology is powerful, easy to use, and is a significant advance in implant dentistry.

Computer-Aided Design↗

Tooth splinting: a review of the literature and consideration of the versatility of a wire-composite splint.

The principles of tooth luxation splinting have been changed since the animal and human tests conducted in the early 1970s showed that masticatory stimulus promotes healing of luxated teeth and normally exerted occlusal forces are able to prevent and eliminate small resorption cavities on the root surface. It has also been shown that fixation of only one week is enough to achieve the clinical healing of repositioned teeth. Apart from esthetic and hygienic components, present-day demands on tooth fixation techniques also include ease of construction and removal and the use of devices which allow slight movement of the fixed teeth. This paper presents the history of tooth splinting, our present-day knowledge of the subject, and introduces various splinting techniques. The wide range of indications for a flexible wire-composite splint are analyzed more thoroughly.

Acrylic Resins↗

Transcutaneous electrical stimulation as an adjunct in the management of myofascial pain-dysfunction syndrome.

Twenty-one patients, 14 women and seven men, presenting with symptoms of the MPD syndrome, were treated with a regimen based on a neuromuscular theory of occlusion involving TES. Evaluation of treatment results shows 95% success immediately after therapy and an 86% success 1 year after therapy. No effort was made to establish a personality profile on the patients nor to incorporate active psychotherapy in treatment.

Adolescent↗

Custom-made condylar inserts for repositioning casts in articulators.

This technique permits temporary repositioning of the condylar elements of a dental articulator for the construction of orthotic prostheses and treatment planning in orthognathic surgery. The procedure is simple and adaptable to various types of articulators in current use. A single set of cast may be mounted in multiple relationships with custom-made inserts that may be retained as a record of the treatment relationship of the casts.

Acrylic Resins↗

Current concepts in the aetiology, diagnosis and treatment of TMJ and muscle dysfunction.

The complexity of managing TMJ and muscle dysfunction is reflected in the variety of treatment modalities that are continually being advocated. The multidimensional nature of the problem is readily appreciated in a TMJ Oral-Facial Pain Clinic where most of the referred patients represent a broad spectrum of treatments that have failed. Where such a clinic has been present for several decades the introduction of new ideas, or the reintroduction of old forms of treatment, are readily seen as well as the quantity and quality of treatment successes and failures. A major shift in ideas concerning the natural history of TMJ/muscle dysfunction, and an explosion of treatment problems and failures related to mandibular repositioning appliances and surgery suggest the need to reconsider various approaches to the diagnosis and treatment of TMJ and muscle dysfunction. Guidelines for diagnosis and treatment of these disorders are discussed.

Analgesics↗

A critical evaluation of orthopedic interocclusal appliance therapy: design, theory, and overall effectiveness.

Orthopedic interocclusal appliances have been evaluated in a number of research papers and clinical reports over the years. Various theories have been proposed about the method of action of the different appliances, but at present no conclusive controlled testing of these theories has occurred. Certainly, when the potential influence of the nonspecific treatment factors is considered, as well as those cognitive awareness factors common to all appliances, the use of "symptom improvement" as the definitive proof of the need for mandibular realignment or repositioning must be questioned. Specific, well-controlled research using more quantifiable measures of the treatment effect is necessary to make valid comparisons between the different therapeutic approaches. The full-arch occlusal stabilizing appliance is the design that has the most valid evidence about its effectiveness. Partial coverage interocclusal appliances have significant irreversible complications with tooth intrusion or eruption when used on an extended basis. There is little or no experimental support at present about repositioning, realignment, and pivot appliances and their effectiveness. Therefore, these appliances must be considered experimental treatments. When used to treat TM dysfunction in a program along with other methods, such as occlusal adjustments, and prosthetic care, the effectiveness of this treatment method is between 70% and 90%. As a general approach to managing TM pain and dysfunction, interocclusal appliances appear to be a highly effective, commonly used method.

Dental Occlusion↗

Selection, application, and management of Phase 1 orthotics.

Once the provisional diagnoses have been obtained and treatment goals established for a temporomandibular disorder patient, an intraoral orthotic is usually part of a phase 1 treatment plan. This overview chapter deals with the selection, fabrication, and management of specific orthotics. A wide array of orthotics are discussed in order of the complexity of their design and fabrication. Each design is considered in light of its benefit/disadvantage ratio.

Dental Occlusion↗

Overlay bit restorer as a Phase 1 orthotic.

Phase 1 (reversible) orthotic therapy is often complicated by missing teeth or the fragile nature of the materials used to construct appliances that must function under the pressures of mastication. The bite restorer combines the strength of Vitallium with the occlusal acceptability of Anodyne to produce an esthetic and functional orthotic without the ill effects of cast metallic overlays. The author uses his experience as a certified dental technician to discuss arch and tooth preparation, clasping, and proper impression technique.

Dental Occlusion↗