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[Human leptospirosis in Martinique].

Eco-geographic conditions are good for spread of Leptospiroses in Martinique. Leptospiroses are widespread in all parts of the Island. Many people have animals in inhabitation area. When they are sought, Leptospiroses can be diagnosed. During 3 years, we found many cases confirmed by biological diagnosis (immunological research of antibodies). Icterohaemorrhagiae is the first serogroup encountered and the most frequent. After follow Canicola, Ballum, Cynopteri and Javanica. Actually, Leptospiroses are a disease more frequent than is generally thought in Martinique. But only the severe cases are hospitalized, so diagnosed. Many cases of fever of unknown origin can be Leptospiroses.

Adolescent↗

[Leptospirosis].

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Antibodies, Bacterial↗

[Serologic diagnosis of human leptospirosis with 3 variants of the passive hemagglutination technique].

A serological study was conducted to evaluate 3 variants of the positive hemagglutination technique (HA) with the use of formalized erythrocytes of fresh lamb (HC) and of formalized Type O, Rh-negative human red blood cells (HH). No significant statistical difference were found between the results of HA and HC and between HC and HH. Unspecific reaction was only observed in 2 of the 200 sera studied by HH and HC. Heterophil antibodies were just observed in 2.5% of the sera studied by HH, and in 100% of the sera studied by HC. The qualitative parameters were determined for the variants used, and this way the repetition and reproducibility of the most useful variant was evaluated.

Hemagglutination Tests↗