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Rowell's syndrome: report of a case.

A 47-year-old woman presented with a long-standing history of an erythema multiforme-like eruption in association with lupus erythematosus. Unusual laboratory and immunologic findings were consistent with a diagnosis of Rowell's syndrome, which includes lupus erythematosus in association with erythema multiforme-like skin lesions, a speckled antinuclear antibody pattern, and a positive rheumatoid factor. We believe that our patient meets the criteria for this rarely reported entity.

Erythema Multiforme↗

Rowell's syndrome.

Rowell's syndrome is the name given to a distinct group of patients with lupus erythematosus who develop erythema multiforme-like lesions and have a characteristic serological picture. We report a case of a 29-year-old woman of Afro-Caribbean origin who presented with an erythema multiforme-like eruption on the hands. Subsequently she developed painful erythematous swellings on the feet and scaly plaques on the forearm and thigh consistent with subacute cutaneous lupus. She developed a positive antinuclear factor and had positive anti-Ro and anti-La antibodies and a positive rheumatoid factor. All of these features are consistent with Rowell's syndrome which we believe is a rare but distinct variant of cutaneous lupus erythematosus.

Adult↗

[Generalized herpes simplex].

This report is about a 58-year-old female patient with generalized herpes simplex virus exanthema. The virus was detected not only in the skin eruptions but also in rinsing liquid from the throat. Its typical feature revealed it to be herpes simplex virus Type I. On the basis of similar cases which have been described in literature, we point out that it is necessary to carry out virological and serological tests in cases of uncertain vesico-pustular or erythema exsudativum multiforme like exanthemas. These exanthemas must be separated from the postherpetic erythema exsudativum multiforme because of the identified virus.

Exanthema↗