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At least 1,693 records · Page 94Linked to original sources
PubMed2005

Managing the CT data explosion: initial experiences of archiving volumetric datasets in a mini-PACS.

Two image datasets (one thick section dataset and another volumetric dataset) were typically reconstructed from each single CT projection data. The volumetric dataset was stored in a mini-PACS with 271-Gb online and 680-Gb nearline storage and routed to radiologists' workstations, whereas the thick section dataset was stored in the main PACS. Over a 5-month sample period, 278 Gb of CT data (8976 examinations) was stored in the main PACS, and 738 Gb of volumetric datasets (6193 examinations) was stored in the mini-PACS. The volumetric datasets formed 32.8% of total data for all modalities (2.20 Tb) in the main PACS and mini-PACS combined. At the end of this period, the volumetric datasets of 1892 and 5162 examinations were kept online and nearline, respectively. Mini-PACS offers an effective method of archiving every volumetric dataset and delivering it to radiologists.

Database Management Systems↗
PubMed2006

Red hot chili pepper and hemorrhoids: the explosion of a myth: results of a prospective, randomized, placebo-controlled, crossover trial.

PURPOSE: Spicy foods are appreciated by a large part of the world population but have been blamed for causing hemorrhoids or exacerbating their symptoms, although no epidemiologic studies have been performed supporting this hypothesis. In this double-blind, randomized, placebo-controlled, crossover trial, we have studied the effects of a single dose of red hot chili pepper on the hemorrhoidal symptoms. METHODS: Fifty patients with second-degree and third-degree symptomatic hemorrhoids were randomly assigned to take a capsule containing red hot chili powder or placebo during lunch, scoring five hemorrhoidal symptoms (bleeding, swelling, pain, itching, and burning) on a visual analog scale. After one week, crossover treatment was administered according to the same methodology. Other treatments and foods potentially related with anorectal symptoms were discontinued during the study periods. RESULTS: Patients assigned low scores to their hemorrhoidal symptoms before the study and the scores remained unchanged during the 48 hours after both placebo and chili pepper treatment, the latter showing no statistically significant effects. CONCLUSIONS: There is no scientific evidence that a spicy meal based on red hot chili pepper may worsen hemorrhoidal symptoms and, therefore, there is no reason to prevent these patients from occasionally enjoying a spicy dish if they so wish.

Adult↗
PubMed2004

LINE-1 amplification accompanies explosive genome repatterning in rodents.

Transposable elements (TEs) sometimes induce karyotypic changes following recombination, breakage and rearrangement. We used FISH and Southern blot analyses to investigate the amount and distribution of LINE-1 retrotransposons in rodents (genus Taterillus, Muridae, Gerbillinae) that have recently undergone an important genome repatterning. Our results were interpreted in a known phylogenetic framework and clearly showed that LINE-1 elements were greatly amplified and non-randomly distributed in the most rearranged karyotypes. A comparison between FISH and conventional banding patterns provided evidence that LINE-1 insertion sites and chromosome breakpoints were not strongly correlated, thus suggesting that LINE-1 amplification subsequently accompanied Taterillus chromosome evolution. Similar patterns are observed in some cases of genomic stresses (hybrid genomes, cancer and DNA-damaged cells) and usually associated with DNA hypomethylation. We propose that intensively repatterned genomes face transient stress phases during which some epigenetic features, such as DNA methylation, are relaxed, thus allowing TE amplification.

Animals↗
PubMed1977

The instrument explosion--a study of aircraft cockpit instruments.

Aircraft cockpit instruments have been increasing in number since the Wright Brothers made their first powered flight. As aeroplane development progresses, new systems are continually being added to improve performance or capability and cockpits have now reached the stage where there is often little space left in which to install the monitoring instruments for these additional systems. Fortunately, the advent of electronic cockpit displays offers a solution to this problem. One electronic display can be used to present the information previously requiring several conventional electro-mechanical instruments, with a consequent saving in cockpit panel space. However, cockpit displays must be matched to the pilot's information requirements and processing abilities. If this is not done the advantages of electronic displays will not be realised and the pilot will be in an even worse position than he was before.

Journal Article↗
PubMed1981

Access to data and the information explosion: oral contraceptives and risk of cancer.

This report describes a technically feasible method to deal with the enormous volume of literature published regarding oral contraceptives. This subject was discussed in 3735 publications during the period from November 1977 through October 1980. Our findings showed that those papers reporting original, numeric relationships involving risk of cancer and use of oral contraceptives were one percent of the total 3735 publications. However, only seven of the 27 articles involved were authored by individuals from departments of obstetrics and gynecology. Further, only four of the 27 were published in journals devoted to obstetrics and gynecology. The analyses suggest a form of censorship taking place, in that the obstetrics/gynecology specialists do not have ready access to the primary data.

Contraceptives, Oral↗
PubMed1990

Hilton Head revisited--cytokine explosion of the 80s takes shape for the 90s.

The Second International Workshop on Cytokines was held two years after its predecessor. The scope was extremely broad--cytokines. This attracted a large and extremely diverse group of participants (700 people and 526 abstracts), interested in many different cytokines (interleukins 1-8, tumor necrosis factors, interferons, colony-stimulating factors, platelet-derived growth factor, fibroblast growth factors and others) from the perspective mainly of research laboratories devoted to studies of diverse disciplines such as immunology, endocrinology, neurobiology, molecular biology, pharmacology and biochemistry.

Animals↗
PubMed1992

Report of nitropatch explosions complicating defibrillation.

Reports of complications associated with the use of electrical defibrillators have been relatively rare. In two patients, defibrillation performed over a nitroglycerin skin patch resulted in electrical arcing with a resultant flash of light and thermal injuries. Skin burns as a complication of defibrillation over nitropatches has not been previously reported. Such burn injuries respond to standard therapeutic measures. Healthcare professionals who may perform defibrillation should be aware of this potential complication.

Administration, Cutaneous↗