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Orbital fractures.

In this paper the importance of the clinical, ophthalmological and radiological examination in the diagnosis of orbital fractures is stressed. Indications for operative treatment can be esthetic or functional, such as enophthalmos or diplopia. A plea is made for early diagnosis and treatment. An open approach is used for all displaced fractures in order to obtain an anatomical reduction. Currently, miniplates and screws are used more frequently for stabilization. Defects in the orbital floor should be covered preferably with autogenous bone or, if unavailable, with bovine cartilage or some synthetic material.

Bone Plates↗

[Supranuclear vertical gaze palsy and convergence nystagmus caused by unilateral riMLF lesion].

We report a case showing supranuclear vertical gaze palsy and convergence nystagmus caused by a unilateral lesion of the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF). The patient was a 54-year-old female with mitral stenosis and regurgitation and atrial fibrillation, who suddenly developed vertigo and double vision. She was admitted to our hospital because of persisting diplopia 4 days after onset, although vertigo had resolved within 1 hour. On admission she was alert, but presented with supranuclear vertical gaze palsy and convergence nystagmus. Other cranial nerves were intact and motor strength, deep tendon reflexes, sensations were also normal. There were no cerebellar signs. Cranial MRI demonstrated a unilateral ischemic lesion at the left thalamo-mesencephalic junction that involved the unilateral riMLF. Cerebral angiography revealed no abnormalities. Vertical gaze palsy has been reported to be caused by a lesion involving bilateral riMLF or unilateral posterior commissure, and convergence nystagmus usually by a lesion near or within the dorsal mesencephalon. However, recent reports have demonstrated a histopathologic evidence that vertical gaze palsy was caused by unilateral riMLF lesion. The present case confirms clinically that both vertical gaze palsy and convergence nystagmus can be developed by a lesion of unilateral riMLF.

Brain Diseases↗

Bilateral internuclear ophthalmoplegia after smoking "crack" cocaine.

A previously healthy 35-year-old man developed sudden diplopia after smoking "crack" cocaine. Neuroophthalmologic examination revealed findings consistent with a tegmental mesencephalic lesion which correlated closely with the computed tomographic documentation of a small midbrain hemorrhage. Cocaine abuse is a recognized cause of intracranial hemorrhage. In most patients, however, the bleeding is localized in the subarachnoid space or the subcortical white matter. To our knowledge, this is the first case of isolated midbrain hemorrhage secondary to cocaine abuse.

Adult↗

[Blow-out fractures in childhood].

Both of large groups, lateral and central facial skull fractures, are further divided into isolated fractures of particular localisation (zygomatic arc, orbital floor fractures etc.) and compound fractures of varying degrees. 33 patients aged 5 to 14 years with fractures of the orbital floor (blow-out fractures) were followed up for 3 months to 9 years. Advances in the primary surgery have contributed to an improvement in the treatment of defects. The present investigation confirms the view that blow-out fractures with diplopia and prolaps in childhood require early surgical treatment.

Adolescent↗

Ophthalmic effects of oximes: a review.

Evidence from controlled clinical trials of oximes indicates that high doses given im or iv may cause transient disturbances of vision. Blurring of vision and diplopia present for up to an hour can occur. These are often accompanied by other side effects such as nausea, epigastric discomfort, drowsiness and dizziness. Visual effects have not been reported following high doses of oximes given po. Experimental studies provide evidence that some oximes given at high dosages may penetrate the blood-brain and blood-aqueous humor barriers. These suggest that the visual effects may be mediated through the CNS and/or by direct effects on the accommodation mechanisms of the eye. Although transient, the visual effects should be taken into account in clinical trials designed to assess the dosage necessary to achieve prophylaxis against OP antiChE poisoning in occupational situations.

Central Nervous System↗

Occult pontine glioma in a patient with hemifacial spasm.

Hemifacial spasm due to an intracranial mass lesion is rare. We describe a 29-year-old man with hemifacial spasm successfully treated with botulinum A toxin injections for 2 years. The development of acquired diplopia secondary to acquired sixth cranial nerve palsy prompted investigation. Computed tomography done at the time of original diagnosis and on three other occasions (concentrating on the brain stem and cerebellopontine angle) failed to demonstrate an intracranial mass lesion. Magnetic resonance imaging (MRI) showed a large mass lesion in the pons presumed to be a glioma. Patients with hemifacial spasm who have atypical features, especially those with associated neurologic findings, should be screened for tumours. Our case illustrates the superiority of MRI in demonstrating pontine gliomas causing hemifacial spasm.

Adult↗

Strabismus caused by melanoma metastatic to an extraocular muscle.

Nonocular melanoma rarely metastasizes to the orbit. We report the case of a melanoma presumably arising from an axillary lymph node sinus that metastasized to the left medial rectus muscle causing proptosis, diplopia, and reduced saccadic velocity measurements. Clinical, radiographic, and histopathologic data are presented and discussed.

Adult↗

Acquired accommodative esotropia following overcorrection by myopic epikeratophakia.

Complications reported after epikeratophakia for high myopia include under- and overcorrection, glare, irregular astigmatism, delayed reepithelialization, and decrease in best-corrected visual acuity. Overcorrection may also result in anisometropia. This report describes a patient who presented with constant diplopia and esotropia--an unusual manifestation of overcorrection after myopic epikeratophakia. The findings in this patient are those of an acquired accommodative esotropia.

Contact Lenses↗

Treatment of dysthyroid myopathy with adjustable suture recession.

Extraocular muscle recessions with adjustable sutures were performed on 32 muscles for diplopia secondary to dysthyroid-myopathy. Orthophoria in the primary position was achieved in 30 of the 32 (94%) 1 day after surgery. All remained orthophoric for at least 6 weeks. Of 20 patients followed for 6 months or more, 12 (60%) remained orthophoric for the full extent of their follow-up (6 months to 8 years), and another three (15%) were asymptomatic with prisms (3, 4, and 8 prism diopters). Thus, a total of 15 of 20 (75%) patients remained asymptomatic at least 6 months after surgery.

Adult↗

[Vascular risk factors in patients with ophthalmoplegia].

The occurrence of high-risk factors for vascular disorders was analysed in a group of 43 patients suffering from diplopia of unknown aetiology. The subjects (25 men and 18 women) were aged between 17 and 78 years. Previously excluded were patients with intracranial or orbital tumors, ocular myositis or myasthenia, multiple sclerosis, endocrine orbitopathy, head trauma, cerebral hemorrhage or aneurysms, leucaemic infiltrates or metastasising tumors. Compared to the control groups of extensive epidemiological studies, the patients showed a higher prevalence of arterial hypertension and diabetes mellitus. Adipositas, lipometabolic disturbance and cigarette smoking were also more frequent. The findings support the hypothesis of a vascular origin of eye-muscle paresis.

Adolescent↗

[Oculomotor paralysis and Lyme disease].

Lyme disease is an infectious multi system disorder caused by the spirochète Borrelia Burgdorferi. Neurologic syndromes occurring during the second stage of the illness are common and the neurologic feature is extremely variable. We report a case of Lyme disease with diplopia. In contrast with most reported cases of ocular motor involvement in Lyme disease, no other systemic symptoms were detected. The serodiagnosis, although mildly positive, was confirmed by western blot antibodies analysis and evaluation of CSF antibodies. Symptoms readily vanished 3 days after the introduction of antibiotherapy. The efficacity of antibiotic therapy on the quality and timing of functional recovery justifies the use of this therapy.

Adult↗

Bilateral ophthalmoplegia during percutaneous transluminal coronary angioplasty.

A 61-year-old woman underwent percutaneous transluminal coronary angioplasty (PTCA) to relieve stenosis of the left anterior descending coronary artery. During the procedure ophthalmoplegia with diplopia developed. The diagnosis was partial right third cranial nerve palsy and left fourth cranial nerve palsy. The cause is presumed to have been a microembolic infarct of the right peripheral third nerve coupled with either decompensation of pre-existing left superior oblique palsy or a separate microinfarct of the left trochlear nerve. Over 7 months of follow-up there was partial resolution of the ophthalmoplegia. Ophthalmoplegia during PTCA is rare, and to our knowledge this complication has not been reported in the ophthalmic literature.

Angioplasty, Balloon, Coronary↗

Side effects of the use of botulinum toxin for treatment of benign essential blepharospasm and hemifacial spasm.

From April 1983 to April 1988, 381 botulinum toxin injections for lid spasms were administered to 106 patients. Sixty-nine had bilateral blepharospasm and 37 had hemifacial spasm. Of the 381 injections, 308 had been given to patients who returned for follow-up examinations. No systemic effects were noted at any of these visits; all side effects were temporary; there were no serious complications. Ptosis, the most frequently encountered problem, occurred after 26 (8.4%) of the injections. Other complications included: corneal exposure (after eight injections, 2.59%); face droop (after 11 injections, 3.57%); diplopia (after five injections, 1.62%); and subtle visual blurring (after eight injections, 2.59%). One patient noted jaw tenseness, another mentioned tearing, one reported brow droop, and another complained of crossed eyes. Ten injections had minimal effect; in these cases a repeat injection usually was effective. Only four patients chose surgery after beginning injections. We conclude that botulinum toxin injections are a safe, effective means of treating lid spasms.

Adolescent↗

[Isolated traumatic rupture of the membrane of Bruch complicated by choroid neovascularization].

The authors report one case of traumatic tear in Bruch's membrane which pass close to the fovea in a thirty year old male. Sub retinal neo-vascularization arise from this choroidal rupture four months after trauma. Binocular diplopia was the first symptom of the sub-retinal neo-vascularization. It extends from the tear to involve the macula with reduction in visual acuity to 2/10eme P14. The spontaneous regression of these abnormal vessels allows to improve visual acuity to 6/10eme P2. Compared with reports in the literature, it seems that spontaneous regression of this sub-retinal neo-vascularization can be explained by the fact it grow from healty retina in young patient. There is no conclusive evidence that coagulation therapy is of any benefit in patients developing such lesions.

Adult↗

[Endonasal ethmoidectomy in the treatment of polyposis].

The authors report their experience with 210 microsurgical ethmoidectomies carried out in 109 patients between 1980 and 1987. In 23 patients the anatomy was considerably modified due to previous surgery. Asthma was present in 56 patients and 25 patients suffered from Widal's syndrome. The complications noted included 1 case of meningitis cured by antibiotics and a case of transient diplopia. Patients were monitored for 1 to 6 years; In 69 cases no recurrence was noted (63% of cases), 31 patients (28%) only required minor local procedures for slight recurrence (28%). On the other hand, 6 patients (5.5%) required a second surgical procedure for recurrence between 3 and 6 years.

Asthma↗

[Eye manifestations of Horton's disease].

Ocular complications occurring in temporal arteritis are of different severities. These manifestations of the disease occurred in a population of 57 patients with diagnosis of temporal arteritis, in 16 of them (28%). The diagnosis was suggested by finding an inflammatory syndrome (high erythrocyte sedimentation rate) and confirmed by temporal artery biopsy. In making this diagnosis, it was helpful to find a history of characteristic temporal headaches, neckache, jaw claudication, fever and malaise or weight loss in addition to polymyalgia and polyarthralgia. 6 patients presented with diplopia and different ocular muscle or nerve palsies. The 10 others came for sudden loss of vision due to ischemic anterior or posterior neuropathy and in one case, central artery obliteration. Prompt treatment with steroids gave good results on oculomotor troubles and in preventing the risk of involvement of the fellow eye. But loss of vision did not regress with this treatment. That means the importance in making this diagnosis and starting very promptly this treatment.

Blepharoptosis↗

An unusual case of painful ophthalmoplegia in a patient with rheumatoid arthritis.

A 43-year-old woman with long-standing rheumatoid arthritis and systemic lupus erythematosus had pain and horizontal diplopia. Clinical symptoms were consistent with inflammation of the right superior oblique tendon sheath, but a computed tomographic scan showed no pathology. Treatment with systemic corticosteroids reduced the symptoms, but the patient was left with a persistent muscle imbalance.

Adult↗