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Stimulus-seeking behavior in hyperactive and nonhyperactive children.

Auditory and visual stimulus-seeking behavior was measured in hyperactive and nonhyperactive youngsters. The design controlled for motor activity level. The results indicate that hyperactive children preferred auditory stimulation more than the control children. There were no differences in stimulus-seeking preferences in the visual modality. The groups did not differ in motor activity. It was concluded that abnormally high needs for stimulation are important in hyperactivity.

Arousal↗

Strategies for reduction and cessation of alcohol use: adolescent preferences.

BACKGROUND: Although the majority of youth and adults resolve alcohol problems without formal treatment, we know little about the strategies used by youth in their efforts to decrease alcohol use. Recent studies have begun to address change efforts that adolescents report being helpful in cutting down or stopping alcohol use. The current study seeks to improve our understanding of adolescent change processes in alcohol use by examining the perceptions of high school students. METHODS: As part of a secondary alcohol intervention study of high school students (ages 12-18; 51% male), 1069 participants completed an anonymous supplemental questionnaire on change strategies for cutting down and stopping alcohol use. Based on content analysis of youth-generated responses, a classification system consisting of nine broad categories was developed (e.g., informal-interpersonal supports, formal aids, alternative activities). Participant responses were independently coded by two raters trained to criterion. Cases with full agreement (n = 934; 96%) were used for data analyses of methods for cutting down drinking, stopping drinking, and strategies recommended for a friend. RESULTS: The five most frequently youth-generated change strategies to alter drinking were environmental exposure management (e.g., avoid drinking situations, 19%); informal interpersonal supports (e.g., talk to a friend, 18%); formal aids (e.g., peer support group, counselor, 17%); behavioral self-management (e.g., limit consumption, 14%); and alternative activities (e.g., recreation, sports, 10%). Whereas informal interpersonal supports were consistently endorsed for all change situations, behavioral self-management strategies were viewed as more useful for reduction of drinking and formal aids more critical for cessation efforts. Some differences were observed in youth-generated strategies for changing their own drinking compared with efforts to help friends, with environmental changes (e.g., reducing exposure to risk situations and people, formal aids) more often considered when changing youth's own behavior, and strategies reflecting a need for personal change (e.g., education) recommended to others. CONCLUSIONS: Our findings support theoretical conceptualizations of alcohol and drug problem resolution that accommodates multiple pathways to recovery. The normative information about specific change strategies generated by youth may further aid in the design of interventions more acceptable for adolescents.

Adolescent↗

Postpartum smoking relapse and becoming a mother.

PURPOSE: To propose an innovative, theoretically-derived conceptual framework for studies of postpartum smoking relapse including concepts of smoking abstinence self-efficacy and becoming a mother. METHODS: Presentation of an existing research paradigm followed by evidence from intervention research and studies of factors associated with postpartum smoking behavior, leading to a new approach to postpartum smoking relapse. FINDINGS: Effectiveness of current interventions to prevent relapse is limited. Variables associated with becoming a mother are missing from studies of postpartum smoking relapse. CONCLUSIONS: Context-specific variables that influence a woman's progression through the stages of becoming a mother might include protective or risk factors that should be incorporated into the design of postpartum smoking relapse studies.

Adaptation, Psychological↗

Long-term care residents' preferences for health states on the quality of well-being scale.

The Quality of Well-Being Scale (QWB) quantifies health-related quality of life with a single number that represents community-based preferences for combinations of symptom/problem complexes, mobility, physical activity, and social activity. The aim of this study was to compare preferences of a long-term care population with those of the general population, determine whether preferences vary by the age of the hypothetical (target) person depicted in the health-state case description, and derive weights for new symptom/problem complexes of particular relevance to frail, older individuals. A sample of 38 female and 12 male long-term care residents with an average age of 86 years was asked to rate health-state scenarios that combined the four health domains of the QWB. This sample rates quality of life 0.10 units lower on average (on a 0-1 scale) than did the general population sample from which the QWB preferences were originally developed. Ratings of the same health state for younger versus older target persons did not differ significantly (all p values > 0.05 for t statistics). Weights derived for 11 new symptom/problem complexes were: disturbed sleep (-0.252), sit-to-stand requires maximal effort (-0.259), lonely (-0.265), walking a short distance causes extreme fatigue (-0.273), agitated (-0.284), hallucinating (-0.355), incontinent (0-359), unable to control one's behavior (-0.36), urinary catheter (-0.374), restrained in bed or chair (-0.374), and feeding tube through the nose or stomach (-0.402). These new weights increase the relevance of the QWB for cost-utility evaluations of health interventions for long-term care residents.

Activities of Daily Living↗

Binding characteristics of chondroitin sulfate proteoglycans and laminin-1, and correlative neurite outgrowth behaviors in a standard tissue culture choice assay.

Neuronal growth cones are capable of sophisticated discrimination of environmental cues, on cell surfaces and in the extracellular matrix, to accomplish navigation during development (generation) and following nervous system injury (regeneration). Choices made by growth cones are commonly examined using tissue culture paradigms in which molecules of interest are purified and substratum-bound. From observations of growth cone behaviors using these paradigms, assertions are made about choices neuronal growth cones may make in vivo. However, in many cases, the binding, interactions, and conformations of these molecules have not been determined. In the present study, we investigated the binding characteristics of two commonly studied outgrowth regulatory molecules: chondroitin sulfate proteoglycans (CSPGs), which are typically inhibitory to neurite outgrowth during development and following nervous system injury, and laminin, which is typically outgrowth promoting for many neuronal types. Using a novel combination of radiolabeling and quantitative fluorescence, we determined the precise concentrations of CSPGs and laminin-1 that were bound separately and together in a variety of choice assays. For identically prepared cultures, we correlated neurite outgrowth behaviors with binding characteristics. The data support-our working hypothesis that neuronal growth cones are guided by the ratio of outgrowth-promoting to outgrowth-inhibiting influences in their environment, i.e., they summate local molecular cues. The response of growth cones to these molecular combinations is most likely mediated by integrins and subsequent activation of signal transduction cascades in growth cones.

Animals↗

How the elderly and young adults differ in the decision making process of nonprescription medication purchases.

The study compared elderly and young adults in their behavior and involvement in the decision making process of over-the-counter (OTC) medication purchases. Elderly subjects were more involved in the decision making process to purchase OTC medications compared to young adults. The elderly not only purchase and spend more money on medications but also read OTC labels completely. They requested help from the pharmacist more frequently than young adults. Needs of the elderly in making an OTC medication purchase were different compared to young adults. The two age groups differed on importance rating for several attributes regarding OTC medications, such as; ease of opening the package, child resistant package, side effects of medicine, manufacturer of medicine, print size on package labels, and greater choice of medicine.

Adult↗

Self-control and impulsiveness in adult humans when food is the reinforcer.

Moderately food- and water-deprived women repeatedly chose between longer access to juice after a long delay (the self-control alternative), and shorter access to juice after a short delay (the impulsive alternative). In contrast to previous experiments using points exchangeable for money as the reinforcer, which have found consistent self-control across subjects, behavior of the present subjects varied between complete self-control and complete impulsiveness. Individual subjects' degree of self-control was not related to their majors, to their past or present degree of reported actual food deprivation, to their ratings of desire for the juice, or to their latency to respond. However, subjects who reported that they were currently dieting were significantly more impulsive; they obtained juice earlier within individual trials but had smaller total juice access time. The operant conditioning laboratory paradigm developed for the present research can be useful in investigating general determinants of self-control and impulsiveness for food reinforcers, as well as in investigating the origins of individual differences in food choice.

Adolescent↗

[Motivational interviewing to help patients stop drinking].

Helping patients to change behavior concerning their drinking is a common task in primary care. This article examines the limitations of using the approach of giving advice and identifies concepts and methods, which offer the promise of improving the quality and effectiveness of consultations about alcohol use. The central role of ambivalence in alcohol dependent patients is explored and practical solutions to resolve ambivalence are described, considering the stages of change model.

Alcoholism↗

Trends in place preference conditioning with a cross-indexed bibliography; 1957-1991.

The purpose of this work is to present a perspective of the conditioned place preference (CPP) test by offering an overview of the empirical research from 1957-1991. The intent is not to extensively analyze the controversies inherent to any behavioral technique but rather to present a survey of research using a descriptive statistics approach to explore topical issues. The objectives of this work are three-fold: (a) to provide an exhaustive bibliography of the CPP literature including articles, journal abstracts, book chapters and critical reviews; (b) to provide a cross-index of identified key words/drugs tested; and (c) to give an overview of selected procedural issues underlying CPP testing.

Animals↗

Self-determination and information seeking in end-stage cancer.

When patients learn that their cancer has recurred after primary treatments or is no longer responding to therapy and no alternative treatment options exist, their motivation to carry on living may be impacted greatly. Using the Self-Determination Theory, this article's reflective analysis explores the unique situation of a woman with end-stage cancer and her continuous motivation to seek information about her illness. Information was gathered during clinical observations and informal conversations. The analysis showed how the patient sought information about her illness, how she manifested motivation, and how the hospital's social environment influenced her behavior. To understand the experience of being confronted with a terminal illness, the following issues are identified: expansion of awareness, life-facing knowledge contradictions, being open-minded and an active explorer of information sources, medical truth, and professional attitudes toward patients' informational needs. Nurses must understand patients' reasons for self-determination when facing illness uncertainty. Reflecting on such situations will strengthen nursing practice.

Adaptation, Psychological↗

Procrastination by pigeons with fixed-interval response requirements.

Two experiments studied the phenomenon of procrastination, in which pigeons chose a larger, more delayed response requirement over a smaller, more immediate response requirement. The response requirements were fixed-interval schedules that did not lead to an immediate food reinforcer, but that interrupted a 55-s period in which food was delivered at random times. The experiments used an adjusting-delay procedure in which the delay to the start of one fixed-interval requirement was varied over trials to estimate an indifference point--a delay at which the two alternatives were chosen about equally often. Experiment 1 found that as the delay to a shorter fixed-interval requirement was increased, the adjusting delay to a longer fixed-interval requirement also increased, and the rate of increase depended on the duration of the longer fixed-interval requirement. Experiment 2 found a strong preference for a fixed delay of 10 s to the start of a fixed-interval requirement compared to a mixed delay of either 0 or 20 s. The results help to distinguish among different equations that might describe the decreasing effectiveness of a response requirement with increasing delay, and they suggest that delayed reinforcers and delayed response requirements have symmetrical but opposite effects on choice.

Animals↗

Facilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole.

Behaviors associated with monogamy, including pair-bond formation, are facilitated by the neuropeptide vasopressin and are prevented by a vasopressin receptor [V1a receptor (V1aR)] antagonist in the male prairie vole. The neuroanatomical distribution of V1aR dramatically differs between monogamous and nonmonogamous species. V1aR binding is denser in the ventral pallidal region of several unrelated monogamous species compared with nonmonogamous species. Because the ventral pallidum is involved in reinforcement and addiction, we hypothesize that V1aR activation in this region promotes pair-bond formation via a mechanism similar to conditioning. Using an adeno-associated viral vector to deliver the V1aR gene, we increased the density of V1aR binding in the ventral pallial region of male prairie voles. These males exhibited increased levels of both anxiety and affiliative behavior compared with control males. In addition, males overexpressing the V1aR in the ventral pallidal region, but not control males, formed strong partner preferences after an overnight cohabitation, without mating, with a female. These data demonstrate a role for ventral pallidal V1aR in affiliation and social attachment and provide a potential molecular mechanism for species differences in social organization.

Animals↗

Associative learning and the control of human dietary behavior.

Most of our food likes and disliked are learned. Relevant forms of associative learning have been identified in animals. However, observations of the same associative processes are relatively scarce in humans. The first section of this paper outlines reasons why this might be the case. Emphasis is placed on recent research exploring individual differences and the importance or otherwise of hunger and contingency awareness. The second section briefly considers the effect of learning on meal size, and the author revisits the question of how learned associations might come to influence energy intake in humans.

Association Learning↗

Low level lead effects on activity under varying stress conditions in the developing rat.

The study was designed to determine whether lead ingestion by nursing rats would affect the way offspring reacted to the stress inducing properties of the test environment both as juveniles and mature rats. Dams were exposed to diets with 0.0, 0.2, 0.4 or 1.0 percent by weight metallic lead. Mean blood-lead levels of pups at weaning were 4, 25, 36 and 55 micrograms/100 ml of blood respectively. The stress factor was varied by (1) changing the test apparatus, i.e., forcing rats to occupy an open field or allowing the animal to be a free agent in the start box of a T-maze; (2) testing rats under a longitudinal and a cross-sectional experimental design to vary familiarity with the apparatus; and (3) comparing behavior in the presence or absence of noise. Reactivity was assessed by examining the inter-and intra-session pattern of ambulations and defecations. Analysis of data revealed that lead treated rats demonstrated the greater response to stress. This response was generally dose related although recovery was dependent upon the test applied and measures taken. The findings provide a conceptual framework to account for varied results across previous studies.

Aging↗

Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice.

A single or repeated administration of morphine in mice produced hyperactivity, conditioned place preference (CPP) and postsynaptic dopamine (DA) receptor supersensitivity. The hyperactivity induced by morphine was evidenced by measuring the enhanced ambulatory activity using a tilting-type ambulometer. CPP effects were evaluated assessing the increased time spent by the mice to morphine and the inhibition of CPP by the decreased time spent by the mice in the white compartment. Postsynaptic DA receptor supersensitivity in mice displaying a morphine-induced CPP was evidenced by the enhanced response in ambulatory activity to the DA agonist, apomorphine (2 mg/kg, s.c.). The intraperitoneal injection of ginseng total saponin (GTS) from the root of Panax ginseng C.A. Meyer (Araliaceae), prior to and during the morphine treatment in mice inhibited morphine-induced hyperactivity and CPP. GTS inhibited the development of postsynaptic DA receptor supersensitivity. A single dose administration of GTS also inhibited apomorphine-induced climbing behavior, showing the antidopaminergic action of GTS at the postsynaptic DA receptor. These results suggest that the development of morphine-induced CPP may be associated with the enhanced DA receptor sensitivity and that GTS inhibition of the morphine-induced hyperactivity and CPP may be closely related with the inhibition of dopaminergic activation induced by morphine.

Animals↗

Eco-ethology of sexual strategies in animals.

This brief review of comparative aspects of sexual strategies in animals, will focus on their behavioral flexibility rather than on fixed action patterns. Discussion will be on why sex is so common, but not universal, in animal species, and why males and females differ in their sexual strategies, and how each individual adapts its strategies according to social and ecological environment. The goal is to suggest to clinical sexologists to be careful in depicting what is pathological and what is an adaptation to a bad ecological or social environment in our species.

Animals↗

Music listening preferences and preadmission dysfunctional psychosocial behaviors of adolescents hospitalized on an in-patient psychiatric unit.

This study investigated the relationship between music listening preferences and preadmission, dysfunctional psychosocial behaviors (PDPB) of 60 adolescents who were hospitalized on an in-patient psychiatric unit. Findings were that hospitalized adolescents who primarily listened to music with negative lyrics/themes had a history of more PDPB than hospitalized adolescents who primarily listened to music that did not contain negative lyrics/themes; and hospitalized adolescents who primarily listened to heavy metal music had a history of more PDPB than hospitalized adolescents who primarily listened to other types of music.

Adolescent↗

[The neurotransmitter basis of mollusk behavior: the control of the choice between exploratory and defensive responses to the presentation of an unknown object].

The role of serotonin and opioid peptides in decision making was studied in the pond snail Lymnaea stagnalis. It was shown that 5-HTP increased the number of searching responses to a sudden presentation of a novel object. Opiate antagonist naloxone decreased the number of searching responses and increased the number of defensive and escape reactions. The effect of 5-HTP and naloxone on decision making appear to be coordinated with their effects on their behavioural state.

5-Hydroxytryptophan↗