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At least 1,675 records · Page 93Linked to original sources

Room-temperature electroluminescence in the mid-infrared (2-3 microm) from bulk chromium-doped ZnSe.

Electroluminescence associated with impact excitation or ionization of deep Cr(2+) impurity centers in bulk ZnSe is reported. A broad signal of mid-infrared luminescence between 2 and 3 microm is observed once the biased bulk ZnSe device runs into a nonlinear conduction regime. Optical powers in the nanowatt range have been measured at room temperature. The different mechanisms involved in this intracenter infrared light emission are discussed.

Journal Article↗

[Device increasing the capabilities of the MUF-5 microspectrophotometer].

Technical data for coordination of the device electric scheme and the MUPH-5 scheme (both with and without the integrator MIU-2) are presented together with a following computer analysis. The device enables to record discrete changes of optical density on the scanning pathway thus giving an advantage in application for quantitative analysis of histochemical enzymatic reaction as compared with the graphic registering.

Electronic Data Processing↗

[Effect of heterogenic irradiation on deviation from Bouguer-Lambert-Beer law in photometric measurements in ultraviolet, visible, and infrared spectra].

The passing and optic-density parameters registered by a photometric device were estimated, on the basis of a simple modeled system, with respect to the ratio between the absorption band width and the heterogeneous radiation degree. The impacts of heterogeneous radiation on the validity of the Bueguer'-Lambert's-Baire's law were elucidated.

Algorithms↗

[Analysis of LCD aging with polarized optical texture and transmission spectrum].

Light radiation experiment was done to a group of liquid crystal display devices, and the influence of light radiation on the display quality of liquid crystal display devices was studied. The changes in their polarized textures after light radiation were observed with a polarized optical microscope. Parallel stripe texture and black holes, which lost extinction function, appeared in liquid crystal texture. With the increase of light radiation time, more and more black holes result, and the area of black holes gets bigger and bigger. The authors tested the transmission spectrum with computer-controlled ultraviolet/visible light spectrometer, finding that the transmission rate declines with the increase of light radiation time. The results show that the appearance of stripe texture and black holes resulted from the changes in liquid crystal molecular structure after ultraviolet radiation, and the occurrence of black holes, which lost extinction function, is the main reason for the continuous decline of transmission rate.

English Abstract↗

[How precise is the optical Cerec impression?].

The purpose of this investigation was to evaluate the precision of optical impressio obtained with the Cerec-device. Cerec provides a linear correlation between z-data and altitude (r = 1), one bit representing 49 microns. Repeated measurements deliver pixel-z-data within a range of +/- 49 microns and surfaceaverages (484 pixel) within +/- 5 microns. Deviations occur near areas with parallel orientation to the direction of measurement.

Ceramics↗

Neuromyelitis optica (Devic's disease) report of one case.

Neuromyelitis optica also named Devic's disease is an acute combined optic neuritis and transverse myelitis. It is thought to be a variant of multiple sclerosis, but its clinical presentation probably has only one attack without further recurrence and exacerbation. We present a 12-year-old girl who suffered from sudden onset of lower extremeties weakness, sensory loss and blurred vision after a prodromal URI symptom. CSF examination showed mild pleocytosis, elevated immunoglobulins, mild elevation of protein concentration. No oligoclonal band was detected. Serum virology showed high titer of anti-EB virus antibody. Visual evoke potential showed prolong of latency and decreased amplitude of both eyes. After prednisolone treatment, her visual accuity began to improve on the 7th hospital day and motor function improved on the 11th hospital day. Two years later, she has normal visual accuity, normal motor function and shows no evidence of disease recurrence.

Antibodies, Viral↗

[A contribution to purification of staphylokinase (author's transl)].

Optimal production of staphylokinase (SAK) was achieved in a casein hydrolysate yeast extract medium (LO3) containing 0.1 M Na-pyruvate. Addition of the pyruvate reduced significantly the production of protease and facilitated purification of SAK. After concentration of SAK from the culture supernatant by precipitation with ZnCl2 highly purified SAK was prepared successively using DEAE-Sephadex A 25 in a batch-procedure, by chromatography on CM-Sephadex C25, filtration with Ultrogel ACA 54, isoelectric focusing between pH 3.5 and 10 (fig. 2) and refocusing between pH 5-7 (table 1). For fractionation by focusing a device was constructed to record pH and optical density together with the fraction number in one diagramm (fig. 1). The purified SAK-preparation had a specific activity of 16.700 units per mg protein. It proved to be free of hemolysins, coagulase, leukocidin, lipase, nuclease, phosphatase, and protease. It was homogeneous upon analyses by diselectrophoresis, double immunodiffusion and immunelectrophoresis.

Chromatography, Ion Exchange↗

A tilting device for three-dimensional microscopy: application to in situ imaging of interphase cell nuclei.

The resolution of an optical microscope is considerably less in the direction of the optical axis (z) than in the focal plane (x-y plane). This is true of conventional as well as confocal microscopes. For quantitative microscopy, for instance studies of the three-dimensional (3-D) organization of chromosomes in human interphase cell nuclei, the 3-D image must be reconstructed by a point spread function or an optical transfer function with careful consideration of the properties of the imaging system. To alleviate the reconstruction problem, a tilting device was developed so that several data sets of the same cell nucleus under different views could be registered. The 3-D information was obtained from a series of optical sections with a Zeiss transmission light microscope Axiomat using a stage with a computer-controlled stepping motor for movement in the z-axis. The tilting device on the Axiomat stage could turn a cell nucleus through any desired angle and also provide movement in the x-y direction. The technique was applied to 3-D imaging of human lymphocyte cell nuclei, which were labelled by in situ hybridization with the DNA probe pUC 1.77 (mainly specific for chromosome 1). For each nucleus, 3-D data sets were registered at viewing angles of 0 degrees, 90 degrees and 180 degrees; the volumes and positions of the labelled regions (spots) were calculated. The results also confirm that, in principle, any angle of a 2 pi geometry can be fixed for data acquisition with a high reproducibility. This indicates the feasibility of axiotomographical microscopy of cell nuclei.

Cell Nucleus↗

The inverted multilayer perceptron as a consistency measuring device in neuroanatomical image analysis.

This protocol describes the use of optical imaging and artificial neural networks to analyze the complex patterns of transsynaptic transfer of WGA-HRP from olfactory bulbar axon terminals to olfactory tubercle projection neurons. This constitutes a unique application of neural networks to pattern recognition in a neuroanatomical tract-tracing study. Furthermore, the type of neural network used in this study, i.e., the inverted multilayer perceptron, possesses a novel construction that suits it for measuring consistency in data clusters. In the experiment described, the perceptron functioned as a consistency measuring device that revealed nonlinear relationships between the site of bulbar injection and the degree of regional labeling in the olfactory tubercle. Nonparametric statistical tests were used concurrently to validate the results of this previously untested form of the multilayer perceptron.

Animals↗

A comparison of the Seeing Optical Stylet and the gum elastic bougie in simulated difficult tracheal intubation: a manikin study.

Management of the difficult airway is one of the major challenges that anaesthetists face. The flexible fibreoptic scope is widely available but its use requires a level of skill, training and continued practice that is not universally found in all anaesthetists, particularly trainees. The Seeing Optical Stylet is a new, semirigid fibreoptic stylet 'scope. We compared the Seeing Optical Stylet with a gum elastic bougie in a simulated Cormack and Lehane Grade 3 laryngoscopy in a manikin. Forty-four anaesthetists were timed while intubating the manikin's trachea with both devices. The mean (SD) time taken with the Seeing Optical Stylet was 20.8 (9.3) s and with the bougie 30 (19.8) s (p = 0.001). Oesophageal intubation occurred six times with the bougie but did not occur with the Seeing Optical Stylet (p = 0.011). We conclude that the Seeing Optical Stylet may be superior to the bougie in difficult tracheal intubation. We feel that the results of this manikin trial are sufficiently encouraging to proceed to a clinical trial in patients.

Clinical Competence↗

From micro- to nanofabrication with soft materials.

Soft materials are finding applications in areas ranging from microfluidic device technology to nanofabrication. We review recent work in these areas, discuss the motivation for device fabrication with soft materials, and describe applications of soft materials. In particular, we discuss active microfluidic devices for cell sorting and biochemical assays, replication-molded optics with subdiffraction limit features, and nanometer-scale resonators and wires formed from single-molecule DNA templates as examples of how the special properties of soft materials address outstanding problems in device fabrication.

Biomedical Engineering↗

Measurement accuracy and cerenkov removal for high performance, high spatial resolution scintillation dosimetry.

With highly conformal radiation therapy techniques such as intensity-modulated radiation therapy, radiosurgery, and tomotherapy becoming more common in clinical practice, the use of these narrow beams requires a higher level of precision in quality assurance and dosimetry. Plastic scintillators with their water equivalence, energy independence, and dose rate linearity have been shown to possess excellent qualities that suit the most complex and demanding radiation therapy treatment plans. The primary disadvantage of plastic scintillators is the presence of Cerenkov radiation generated in the light guide, which results in an undesired stem effect. Several techniques have been proposed to minimize this effect. In this study, we compared three such techniques-background subtraction, simple filtering, and chromatic removal-in terms of reproducibility and dose accuracy as gauges of their ability to remove the Cerenkov stem effect from the dose signal. The dosimeter used in this study comprised a 6-mm(3) plastic scintillating fiber probe, an optical fiber, and a color charge-coupled device camera. The whole system was shown to be linear and the total light collected by the camera was reproducible to within 0.31% for 5-s integration time. Background subtraction and chromatic removal were both found to be suitable for precise dose evaluation, with average absolute dose discrepancies of 0.52% and 0.67%, respectively, from ion chamber values. Background subtraction required two optical fibers, but chromatic removal used only one, thereby preventing possible measurement artifacts when a strong dose gradient was perpendicular to the optical fiber. Our findings showed that a plastic scintillation dosimeter could be made free of the effect of Cerenkov radiation.

Artifacts↗

Diffractive variable beam splitter: optimal design.

The analytical expression of the phase profile of the optimum diffractive beam splitter with an arbitrary power ratio between the two output beams is derived. The phase function is obtained by an analytical optimization procedure such that the diffraction efficiency of the resulting optical element is the highest for an actual device. Comparisons are presented with the efficiency of a diffractive beam splitter specified by a sawtooth phase function and with the pertinent theoretical upper bound for this type of element.

Equipment Design↗

A mobile and navigated image viewer for surgery--evaluation of precision.

We report work on a newly developed and ultra compact mobile viewing device, called NaviView to display medical imaging data (i.e. from a computer tomograph--CT) in situ. The system comprises an optical tracking system to detect both the patients and the viewing devices position and display a proportionable part of the medical image data on a mobile viewing device. This article describes experiments carried out to evaluate the overlay precision of two different imaging modalities (i.e. live video and CT) being visualized.

Computer Simulation↗

Accuracy of movement tracking with a miniaturized second-generation Moiré device.

The availability of a Nanoform 600, a machine used in the contouring of optical components, with movement capabilities of 12.5 A, made it possible to determine the sensitivity, accuracy and movement tracking ability of a high-resolution measuring device using the principle of Moiré magnification. The Nanoform 600 was programmed to make a series of movements measured by the Moiré device. Comparison of the Moiré measurement with the programmed movements verified that the Moiré device is capable of reliably tracking movements as small as 0.05 microm. Increasing the rate of movement had little effect on linearity. Tracking movements over a 350 microm distance at rates of up to 340 microm per second resulted in a 0.23% error. Intentionally defocusing the Moiré signal did not appreciably affect sensitivity.

Humans↗

Optical immunosensing systems--meeting the market needs.

Optical immunosensors and sensing systems are biosensors which produce a quantitative measure of the amount of antibody, antigen or hapten present in a complex sample such as serum or whole blood. The market needs for such devices and their associated instrumentation are reviewed. A brief history of the development of optical immunosensors is presented and the performance of the most well-developed optical immunosensors for meeting these market needs is reviewed. One device, the fluorescent capillary fill device (FCFD) is reviewed in detail with respect to it fulfilling the market needs for an optical immunosensor. Areas for the future development of such sensing systems are also discussed.

Biosensing Techniques↗

Coupled Mach-Zehnder interferometer memory element.

Two active Mach-Zehnder interferometers are integrated in a monolithic InP/InGaAsP photonic integrated circuit. Together they form a crucial component for optical signal processing: an optical memory element or set-reset flip-flop. The switching time for this initial device is approximately 200 ps. The photonic integrated circuit contains active and passive optical components, including electro-optic phase shifters.

Journal Article↗