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At least 1,675 records · Page 93Linked to original sources
PubMed1997

Great grand multiparity: is it a risk?

OBJECTIVE: To compare antenatal and intrapartum complications incidence among women delivering for the 10th time or more and to compare this with those of low parity (para 2-5). METHODS: The records of (154) women of great grand multipara (para > 10) were reviewed and compared with (308) women (para 2-5) delivered during the same period. Antepartum as well as intrapartum complications were compared, all occurring between 16 April 1994 and 15 January 1995. RESULTS: Great grand multiparous women are older. The incidence of diabetes mellitus, chronic hypertension and preterm labor are similar to those with low parity, while they have higher incidences of pre-eclampsia (7.1% vs. 2.69%) and intrauterine fetal death (5.2 vs. 1.3%) P < 0.025. There were no differences in the incidences of placental abruption, placenta previa, malpresentation, postpartum hemorrhage and operative delivery between the two groups. Great grand multipara also have a higher incidence of macrosomia (12% vs. 12%) P < 0.0001. CONCLUSION: Great grand multiparous woman are at increased risk of having pre-eclampsia, intrauterine fetal death and macrosomia.

Adult↗
PubMed1983

Operative considerations in the obese pregnant patient.

Many obstetricians feel that obesity is associated with a general increase in risks during pregnancy. However, there is some suggestion that obese patients may actually have a decreased risk of premature delivery and delivering small-for-gestational-age infants. Multiple studies have found that even though maternal medical complications are more likely in obese mothers, neonatal outcome can still be excellent in this group. Earlier reports found that the obese mother was at greater risk of abnormal labor and operative delivery. However, recent studies in which nonobese patients have been used as a control group have not found massively obese mothers to be at greater risk of labor abnormalities. Cesarean sections are more common in the overweight mother. The increase in cesarean birth is most likely due to an increase in previous abdominal delivery performed because of increased maternal diabetes and hypertension. Primary cesarean section due to cephalopelvic disproportion does not appear to be increased. When cesarean section is necessary in the massively obese patient, there is clearly an increase in operative morbidity and mortality. The guidelines listed in this article can be instituted best by obstetricians and anesthesiologists experienced in treating massively obese patients. By implementing this special care without undue delay when abdominal delivery is indicated, hopefully maternal and neonatal outcome can be optimized.

Birth Weight↗
PubMed2006

On-chip Escherichia coli culture, purification, and detection of expressed proteins.

In a recent study, we reported the results of a rapid high-throughput expression analysis of the affinity-tagged proteins present in total cell lysates, using a surface plasmon resonance (SPR) imaging protein chip system. In this paper, we describe a novel method, which is able to sequentially carry out a recombinant Escherichia coli culture, as well as the detection and purification of the expressed proteins on a single microwell chip, fabricated on a two-dimensional thin gold film. Following the induction of the protein on the microwell chip, the E. coli cells were lysed on the chip via the addition of lysozymes, and the expressed glutathione S-transferase-fused green fluorescent protein (GST-GFP) was then purified on the chip via affinity interaction with the glutathionylated gold surface of the chip. Finally, the expressed protein was directly detected using the surface plasmon resonance (SPR) imaging system. This system saves a substantial amount of time, experimental resources, and labor, by allowing for the complicated and labor-intensive procedures inherent to the production of recombinant proteins to be conducted on a single microwell chip, simply and economically.

Electrophoresis, Polyacrylamide Gel↗
PubMed1995

Genital burns and vaginal delivery.

Obstetric complications may result from burn scarring in the genital area. Women in developing countries typically squat around cooking fires, and burns are common. This recent case in Nepal describes obstructed labor in a young woman whose genital area had extensive scarring from a cooking fire injury. Proper antenatal assessment by health care providers can reduce the risk to mothers and infants of the consequences of a birth canal damaged or obstructed by burn scarring.

Adolescent↗
PubMed1978

Compound presentation following external version.

Two cases of compound presentation following external version are presented. The frequent combination of the feet with the vertex following this procedure and its association with a higher fetal mortality, interference rate, and obstructed labour than the hand and vertex combination are highlighted. The aetiology, problems in diagnosis, and management are discussed. Measured to prevent and deal with this complication are suggested.

Adolescent↗
PubMed1986

Investigation into the use of prostaglandin F2 alpha (PGF2 alpha) and oxytocin for the induction of farrowing.

This experiment was conducted in order to compare the effects of injecting PGF2 alpha alone, PGF2 alpha with oxytocin and placebo on the induction of farrowing in swine and to compare the relative effects of 3 different dosages of oxytocin (10, 20 and 30 iu per animal) when combined with PGF2 alpha (10 mg). The findings revealed that animals treated with 30 iu oxytocin farrowed within 10.6 h which was similar to those receiving PGF2 alpha only (9.4 h), but shorter than control animals (53.6 h). Animals receiving 20 and 10 iu of oxytocin farrowed within 1.4 and 1.7 h, respectively. Difficult farrowings requiring manual assistance occurred in 30%, 30%, 50% and 10% of sows given 30 iu, 20 iu and 10 iu of oxytocin and in the control group, respectively. Thirteen of 73 sows treated with PGF2 alpha farrowed within 12.6 +/- 5.3 h. Stillbirths were highest (10.2%) in the control animals whilst in the others it was under 7%. Oxytocin at dosages of 20 and 10 iu, seemed most promising in terms of synchronising farrowing following PGF2 alpha treatment in swine. However, farrowing complications were more common in these groups.

Animals↗