Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Technology”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,657 records · Page 92Linked to original sources

The history, science, and innovation of Holter technology.

Holter technology has endured for more than 40 years, and proven to be a valuable adjunctive noninvasive diagnostic technology to record the ambulatory or long-term electrocardiogram in the study of living creatures. During this span of time, many scientists, physicians, and innovators contributed to the development and evolution of Holter technology. This essay seeks to document a view of the history and evolution of the technology during that time, and concomitantly give recognition to the scientists, physicians, and engineers who contributed so greatly.

Cardiology↗

The nurse-technology relationship: the case of ultrasonography.

OBJECTIVE: To examine the nurse-technology relationship via a case study of ultrasonography in women's health nursing practice. DESIGN: Exploratory case study using ethnographic methods. SETTING: Outpatient obstetric and gynecology clinic of a large teaching hospital. PARTICIPANTS: Three nurses, two technicians, and one physician. RESULTS: Two of the nurses and the physician were very "nurse-like" in their use of the technology of ultrasonography to fulfill the traditional nursing purposes of observation, teaching, and comforting. The third nurse was nurse-like in talk, but at times "technician-like" in performance, allowing the technology to pull her away from nursing purposes. CONCLUSIONS: The expert nurses bent the technology to nursing purposes. Sonographers performed in accordance with professional training and experience, rather than with gender expectations. The subtle differences between expert nurse use and technical use (by novice nurses or technicians) of ultrasonography may provide a strong rationale against current efforts to substitute technically trained or technically oriented personnel for expert nurses.

Attitude of Health Personnel↗

Urban-rural differences in the availability of hospital information technology applications: a survey of Georgia hospitals.

CONTEXT: Information technology (IT) has been identified as a potential tool for improving the safety of health care delivery. PURPOSE: To determine if there are significant differences between urban and rural community hospitals in the availability of selected IT functional applications and technological devices. METHODS: A mailed survey of community hospitals in Georgia assessing the current availability of IT applications (54.6% response rate). FINDINGS: Georgia hospitals reported having 63.6% of 56 possible functional applications computerized but only 52.9% of 41 technological devices. Compared to rural hospitals, urban hospitals had significantly more functional applications computerized (38.0 vs 31.8, P = .031) and technological devices available (23.9 vs 18.2, P = .016). Urban hospitals had significantly (P < .05) more IT applications available in 4 areas: emergency room services (7 of 10), surgical/operating room (8 of 12), laboratory (7 of 12), and radiology (5 of 11). Overall, the availability of IT applications was bimodal in rural hospitals: over 40% of rural hospitals had adopted over 70% of all applications, while approximately 26% of rural hospitals had adopted less than 30%. CONCLUSIONS: Some of the observed urban/rural differences in availability of IT applications may be due to differences in the scope of services provided by rural hospitals, in particular laboratories, radiology departments, emergency rooms, and surgery/operating rooms. Nevertheless, the bimodal distribution of IT applications adopted in rural hospitals raises concerns about the ability of selected rural hospitals to take advantage of regional data-sharing initiatives and maintain quality of patient care in the future.

Georgia↗

Using engineering and assistive technologies for rehabilitation after electrical trauma.

A framework is presented for judging when, how, and why rehabilitation engineering and its related assistive technologies are appropriate interventions following electrically induced trauma or burns. Instead of relying on the World Health Organization's medically based classification scheme of "Impairment, Disability, and Handicap," this newer framework is built on a rational demarcation proposed by the National Center for Medical Rehabilitation and Research at the U.S. National Institutes of Health. This latter client-centered framework encompasses pathophysiology, impairment, functional limitations, "disability", and societal limitations. This framework is well suited to handle the varied sequelae of electrical trauma and burn injuries and provides guidance towards the most effective use of traditional rehabilitation interventions and of assistive technologies. For electrical injuries, rehabilitative technologies can be classified as those promoting job accommodations (i.e., that help an individual return to active employment, albeit possibly in a different role) or as aids to the other activities of daily living (ADLs) that provide an enhanced quality of life to the individual with disability. While the traditional rehabilitative focus has been on return-to-work, especially among professional tradesmen, a more productive rehabilitative effort in some cases may occur through psychosocial adjustments achieved via effective technological interventions that enhance ADLs.

Accidents, Occupational↗

Cancer biomarker validation: standards and process: roles for the National Institute of Standards and Technology (NIST).

Rigorous validation of biomarkers for early detection of cancer differs at the National Institute of Standards and Technology (NIST) from similar processes common among research laboratories. As a newly discovered biomarker assay makes the transition from a research setting to the clinical diagnostic laboratory, it should progress through defined stages of assay confirmation. The first task of a validation laboratory is evaluation of research assay technology, performance, and specifications (analytical validation). However, the ultimate goal is initial validation of the test to identify early stage cancer (clinical validation). Upon technical and clinical confirmation, assays are moved systematically toward a standardized, reproducible, high-throughput format for clinical diagnostic implementation. With laboratory performance rigorously established, the clinical variables can subsequently be analyzed to define limitations, applications, and clinical utility. The role of NIST in technology evaluation for early cancer testing is described in the context of similar programs and prior experience at NIST. Here we conceptualize the validation steps of cancer test development and examine how NIST activities impact health care through institutional focus on measurement, technology, and standards development programs.

Biomarkers, Tumor↗

Membrane technologies applied to textile wastewater treatment.

This paper describes the experimental results of a pilot-scale application of membrane technologies to textile wastewater advanced treatment, downstream of a biological activated sludge process, aimed at water reuse in textile technology processes. The chosen approach consisted of sand filtration as a pretreatment, a microfiltration (MF) or ultrafiltration (UF) membrane process, and a final separation treatment performed by means of a nanofiltration (NF) or a reverse osmosis (RO) membrane. An experimental study to compare spiral wound membranes, operating under pressure, to flat membranes, operating under vacuum was conducted. The technical results and a preliminary economic analysis indicate the possibility of technological transfer of the membrane technologies to an industrial scale for textile wastewater reclamation.

Journal Article↗

Scott Wallace on the National Alliance for Health Information Technology. Interview by Deborah Mears.

The National Alliance for Health Information Technology (NAHIT) appointed Scott Wallace as its first president and CEO in 2003. NAHIT is an organization of 90 Leading healthcare associations, suppliers, vendors, hospitals, and healthcare systems committed tothe development of voluntary standards for health information technoLogy. Wallace previously was the principal owner of Great kes Capital, a financiaL, commerciaL, and business development consulting firm with a major focus in technology. Prior to starting Great Lakes, Wallace led several technoLogy-based companies. He served as president and CEO of PowerClip Co., a wireless products mpany; president and CEO of Eichrom Industries, an advanced materials and specialty chemical company; and vice president and general counsel for GCI, a venture capital fund. Wallace earned a juris doctorate from the University of Chicago Law School, a master's degree in business administration from the University of Chicago Graduate School of Business, anda bachelor's degree in economics from Duke University.

Centers for Medicare and Medicaid Services, U.S.↗

David Brailer on a private-public health information technology infrastructure. Interview by Susan V. White.

David Brailer, MD PhD, was appointed the first National Health Information Technology Coordinator by the U.S. Department of Health and Human Services Secretary Tommy Thompson on May 6, 2004. As National Coordinator he is to execute President Bush's Executive Order of April 27, 2004, calling for widespread deployment of health information technology (HIT) within 10 years. Dr. Brailer is an authority on clinical data sharing, local health information exchanges, and the use of peer-to-peer technologies in healthcare. He is a leader in the strategy and financing of quality and efficiency in healthcare, with a particular emphasis on HIT and health systems management. Previously, Dr. Brailer was a Senior Fellow at the Health Technology Center in San Francisco, advising a variety of regional and national data-sharing projects and several major corporations about the role of IT in improving the quality of healthcare. Dr. Brailer recently completed 10 years as Chairman and CEO of CareScience, Inc., a provider of care management services and Internet-based solutions that help reduce medical errors and improve physician and hospital-based performance. Dr. Brailer holds doctoral degrees in both medicine and economics. While in medical school, he was a Charles A. Dana Scholar at the University of Pennsylvania School of Medicine and the first recipient of the National Library of Medicine Martin Epstein Award for his work in expert systems. Dr. Brailer was among the first medical students to serve on the Board of Trustees of the American Medical Association.

Diffusion of Innovation↗

From paper to electron: how an STM journal can survive the disruptive technology of the Internet.

The Internet represents a different type of technology for publishers of scientific, technical, and medical journals. It is not a technology that sustains current markets and creates new efficiencies but is, rather, a disruptive technology that could radically alter market forces, profit expectations, and business models. This paper is a translation and amplification of the research done in this area, applied to a large-circulation new science journal, Pediatrics. The findings suggest that the journal of the future will be electronic, have a less volatile cost structure, be supported more by services than by content, be less able to rely on subscription revenues, and abandon certain elements of current value networks. It also provides a possible framework for other publishers to use to evaluate their own journals relative to this disruptive technology.

Advertising↗

Information technology in medical education: current and future applications.

Information technology has the potential to revolutionise the way medicine is learned by students and healthcare professionals. This potential was recognised by the General Medical Council in their 1993 report Tomorrow's doctors in which the need for future generations of doctors to be familiar with the application and scope of information technology is described. This paper focuses on the use of computers as aids to learning medicine and discusses two key applications of information technology to medical education: multimedia and the internet. The current use and potential for these areas of information technology are described and future developments discussed.

Adult↗

Decision technologies and the independent professional: the future's challenge to learning and leadership.

Most references to "leadership" and "learning" as sources of quality improvement in medical care reflect an implicit commitment to the decision technology of "clinical judgement". All attempts to sustain this waning decision technology by clinical guidelines, care pathways, "evidence based practice", problem based curricula, and other stratagems only increase the gap between what is expected of doctors in today's clinical situation and what is humanly possible, hence the morale, stress, and health problems they are increasingly experiencing. Clinical guidance programmes based on decision analysis represent the coming decision technology, and proactive adaptation will produce independent doctors who can deliver excellent evidence based and preference driven care while concentrating on the human aspects of the therapeutic relation, having been relieved of the unbearable burdens of knowledge and information processing currently laid on them. History is full of examples of the incumbents of dominant technologies preferring to die than to adapt, and medicine needs both learning and leadership if it is to avoid repeating this mistake.

Decision Support Systems, Clinical↗

Increasing the efficiency of suckled calf production using embryo transfer technology.

The data reviewed in this paper illustrate the benefits of increased output that can be obtained from suckler herds using embryo transfer technology. The technology can be used within breeding schemes to increase the rate of genetic progress for selected traits or to transfer embryos of superior genetic merit and, in the future, embryos of predetermined sex to beef cows. The success of the technology is dependent on the achievement of good pregnancy rates. Experience gained on commercial farms suggests that the main reason for poor success rates in some herds lies with the general level of management of such herds rather than with the reproductive technology itself. Much experience has been gained on the management of embryo transfer recipients and twin-bearing cows. In particular, the nutritional requirements of such animals during the early post partum period and during mid and late pregnancy, and the management of twin-bearing cows during the perinatal period, are discussed.

Animals↗

Digital mammography and related technologies: a perspective from the National Cancer Institute.

The National Cancer Institute held a workshop entitled "Breast Imaging: State-of-the-Art and Technologies of the Future" in September 1991. This article describes some of the presentations given at the workshop as well as relevant data in the literature and discusses their implications. The workshop faculty identified digital mammography as the evolving technology with the greatest potential impact on management of breast cancer. On the basis of the workshop findings and literature review, the author proposed to form the National Digital Mammography Development Group, which will stimulate research in digital mammography and its integration with related technologies: image processing for improved lesion contrast, automated computer-aided diagnosis for enhanced breast cancer detection and characterization, and teleradiology for facilitated radiologic consultation with recognized experts in the field. It is expected that the National Digital Mammography Development Group will facilitate transfer of advanced digital imaging technology to breast cancer clinics.

Female↗

Randomly Amplified DNA Fingerprinting: A Culmination of DNA Marker Technologies Based on Arbitrarily-Primed PCR Amplification.

Arbitrarily-primed DNA markers can be very useful for genetic fingerprinting and for facilitating positional cloning of genes. This class of technologies is particularly important for less studied species, for which genome sequence information is generally not known. The technologies include Randomly Amplified Polymorphic DNA (RAPD), DNA Amplification Fingerprinting (DAF), and Amplified Fragment Length Polymorphism (AFLP). We have modified the DAF protocol to produce a robust PCR-based DNA marker technology called Randomly Amplified DNA Fingerprinting (RAF). While the protocol most closely resembles DAF, it is much more robust and sensitive because amplicons are labelled with either radioactive 33P or fluorescence in a 30-cycle PCR, and then separated and detected on large polyacrylamide sequencing gels. Highly reproducible RAF markers were readily amplified from either purified DNA or alkali-treated intact leaf tissue. RAF markers typically display dominant inheritance. However, a small but significant portion of the RAF markers exhibit codominant inheritance and represent microsatellite loci. RAF compares favorably with AFLP for efficiency and reliability on many plant genomes, including the very large and complex genomes of sugarcane and wheat. While the two technologies detect about the same number of markers per large polyacrylamide gel, advantages of RAF over AFLP include: (i) no requirement for enzymatic template preparation, (ii) one instead of two PCRs, and (iii) overall cost. RAF and AFLP were shown to differ in the selective basis of amplification of markers from genomes and could therefore be used in complementary fashion for some genetic studies.

Journal Article↗

RNAi knock-down mice: an emerging technology for post-genomic functional genetics.

RNA interference (RNAi) has been extensively used for sequence-specific silencing of gene function in mammalian cells. The latest major breakthrough in the application of RNAi technology came from experiments demonstrating RNAi-mediated gene repression in mice and rats. After more than two decades of functional mouse research aimed at developing and continuously improving transgenic and knock-out technology, the advent of RNAi knock-down mice represents a valuable new alternative for studying gene function in vivo. In this review we provide some basic insight as to how RNAi can induce gene silencing to then focus on recent findings concerning the applicability of RNAi for regulating gene function in the mouse. Reviewed topics will include delivery methods for RNAi-mediating molecules, a comparison between traditional knock-out and innovative transgenic RNAi technology and the generation of graded RNAi knock-down phenotypes. Apart from the exciting possibilities RNAi provides for studying gene function in mice, we discuss several caveats and limitations to be considered. Finally, we present prospective strategies as to how RNAi technology might be applied for generating conditional and tissue-restricted knock-down mice.

Alleles↗

2-in-1 shampoo technology: state-of-the-art shampoo and conditioner in one.

Consumers have expressed a need for cleaning and conditioning in one step. Conventional shampoo technology using anionic surfactants and cationic conditioners results in charge interaction and complexing of the ingredients. Neither shampoo nor conditioners achieves the desired result. The successful solution was to incorporate charge neutral dimethicone conditioning ingredients, suspended as microfine droplets within complex crystal lattices, into anionic surfactant shampoo technology. The same solution has also been applied to amphoteric surfactant systems. This provides complete cleaning, and hair conditioning fully equal to separate conditioners without the problems of sebum interactions and conditioner build-up. This was achieved by keeping the dimethicone in suspension throughout the shampoo process. During rinsing, excess water breaks the crystalline lattice and allows deposition of the dimethicone droplets onto the hair. Full cleaning and conditioning are, therefore, achieved in one application. Dimethicone build-up is not encountered as subsequent washes first remove soil and previously deposited dimethicone. Neither do neutral dimethicones show any reactions with sebum. The development of effective 2-in-1 technology has had a major impact on shampoo technology and consumer habits and practices. This has significantly changed the way consumers care for their hair.

Hair↗

Pilot scale evaluation of sorting technologies for CCA treated wood waste.

Two sorting technologies including a chemical stain method and an x-ray fluorescence technique were investigated for separating chromated copper arsenate (CCA) treated wood from other wood types in the wood waste stream. Stains were investigated in both laboratory and field settings. Studies included specially mixed solutions with chrome azurol, 1-(2-pyridylazo)-2-naphthol (PAN) and rubeanic acid chemicals. X-ray fluorescence was tested in the laboratory using a commercially available x-ray fluorescence spectrometer. Laboratory scale experiments showed that both technologies were able to detect CCA treated wood in mixtures of treated wood and untreated wood, with detection limits on the order of 3 to 5% CCA. Results from field experiments at construction and demolition facilities indicate that although the chemical stains can be effectively used to identify CCA treated wood waste in field settings, their use will be limited to sorting relatively small wood waste piles due to increased labor and time needed for processing the wood waste. Operational parameters for sorting using x-ray fluorescence technology were established. These parameters concluded that arsenic was the most sensitive metal for analysis, analysis time was less than 2 seconds per wood sample, and the maximum separation distance between the sample and the x-ray probe was 2.5 cm. X-ray technology shows considerable promise for separating large quantities of CCA-treated wood from other wood types in the field using an on-line sorting system.

Arsenates↗

The future of nursing in a technological age: computers, robots, and TLC.

The computer has become a major tool in the medical treatment of disease. Computers can record vital signs, keep records, and provide central networks for interactive diagnosis. Individual medical histories can be contained in an optical card the size of a credit card. Advances in technology just over the horizon will permit an individual to consult a computer much as one now consults a physician for diagnosis, recommendations, instructions, and treatment. Surgery can be conducted in "virtual space," with the physician operating inside the body (via computer) as if he or she were present at the site of the surgery. Only a step beyond this is the development of robots who can do a better surgical job than a human being. What is missing from this scenario? Tender loving care. That is the nurse's job, and it is something that computers cannot do because it involves feelings and human communication that are beyond mere technology. Consequently, nurses will be needed long after physicians have passed into limbo. The practical lesson of this look into the future is that, although nurses certainly must remain in touch with the cutting edge of technology, their primary purpose will be to retain and sharpen the skills that Florence Nightingale introduced. Human response will never be replaced by technology, and the unchanging need for the nurses' caring function will assure their future.

Computers↗