ARTHRITIS MUTILANS AND PSORIASIS.
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There has been much debate as to the movement or otherwise of the sacro-iliac joint. This paper sets out to review the extensive literature on the subject and supplement it with experimental work to show the ability of the joint to move. The movement is greater in women and in patients with definite clinical symptoms. The basic methods of treatment, both in hypomobility and hypermobility, are discussed.
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The histocompatibility antigen W27 has been found to have a high incidence in ankylosing spondylitis (96%), Reiter syndrome (74%), and other forms of arthritis that may involve the axial skeleton. In patients with Reiter syndrome, there was no correlation between the presence of W27 antigen and the extent or duration of the symptoms. Sacroiliitis was predominantly found in those patients with W27 antigen in all the axial arthropathies. Tissue-typing techniques may be of value in detecting early or atypical disease.
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