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PubMed1988

[Clinical course and risk factors in patients with generalized mycoses].

A retrospective analysis of the clinical course of disseminated fungal infections in 32 patients revealed 25 cases of candidiasis, 5 patients with aspergillosis, and 2 with mixed fungal infections. All patients had undergone cytostatic therapy for malignant hematological diseases as the predisposing risk factor for fungal infection. 30 patients had severe granulocytopenia (less than 500/cmm). In addition, 30 patients had received broad spectrum antibiotics and 16 had been treated with corticosteroids. 17 of 32 patients were treated systemically with antimycotic drugs for proven fungal infection. No antimycotic agents were given to 15 patients because fungal infections were diagnosed only on post mortem examination. 19 patients succumbed to overwhelming disease, including 5 in spite of antimycotic therapy. Patients in whom systemic candidiasis was detected after recovery of granulocytopoeisis had a better prognosis than patients who developed systemic fungal infections during the period of ongoing severe granulocytopenia.

Adult↗
PubMed1988

[Mycoses caused by Trichophyton megninii in Galicia (with review of the taxonomy of this dermatophyte)].

The taxonomy of the dermatophyte Trichophyton megninii has been the subject of much discussion since it was first isolated by Sabouraud in 1893. Initially he named it Trichophyton à culture rose and later T. rosaceum. It has been confused with the Microsporum (Epidermophyton) gallinae described by Megnin. Nowadays most mycologists consider T. rosaceum to be a synonym of the T. megninii, although some French authors still use Sabouraud's denomination. It is an exclusively anthropophilic dermatophyte with a broad geographic distribution, but in general a low incidence in most countries, except in Portugal, Corsica and Sardinia where it causes infections of both hairy and glabrous skin zones and nails in humans. T. megninii is an uncommon cause of ringworm in Spain and is mainly restricted to Galicia, and even there the incidence is low; it has been isolated only five times in our clinical practice with two more cases described previously in the literature, and predominantly affects females. Case reports show that it produces slowly evolving lesions with little local symptomatology on the scalp and is recalcitrant to conventional antifungal treatment. Its identification in culture should be based on the macroscopical appearance of the colony and by its absolute requirement for 1-histidine.

Adult↗
PubMed1977

[Mycoses].

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Candida albicans↗
PubMed1986

[Prevalence of superficial mycoses in the adult population of the Brazil-Colombia frontier].

A microbiological study was performed in the adult population of tier Brazil-Colombia, a very damp place with warm weather. It was observed a higher prevalence of P. versicolor (41.5%) and candidiasis (28.09%), followed by P. hortai and E. floccosum. The T. Tonsurans was the principal agent of the trichophitics of the hair. It's a higher prevalence of superficial mycosis was observed in the male.

Brazil↗