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[Diagnostic and incidence of the rupture of the posterior cruciate ligament].

The purpose of this article is to evaluate the incidence and to give a general review of the examination of the posterior ligament complex. At least ca. 8-10 % of all severe ligament injuries concern the posterior cruciate ligament, which means, that an estimated 4,000-5,000 Germans suffer a PCL rupture every year. Motor-vehicle accidents are the most common cause of the injury, but sports-related traumas (football, skiing) have increased in recent years. The high number of high-energy mechanisms involved (up to 90 %), cause ligament ruptures often to be associated with other injuries, especially fractures of the femur and tibia head. In polytrauma patients PCL ruptures are frequently recognized very late, because the possibility of this kind of injury is often not considered during the clinical examination. The same holds for the diagnosis of monotrauma patients. The initial step in the evaluation is to obtain a thorough history (including the mechanism of injury) and to perform a physical examination. The instability after a PCL rupture may present as an ACL rupture, because the anterior drawer test seems to be positive. The anterior/posterior drawer test must be assessed with other evaluation procedures to distinguish between anterior und posterior instabilities. The posterior sag sign, the quadriceps active test or the reversed pivot-shift may indicate a PCL rupture. A correct roentgenogram can reveal an avulsion of the tibia and can prove posterior instability due to a posterior translation of the tibia. A quantitative examination (clinical or X-ray) of the instability and the indication of combined injury of the posterior cruciate ligament and the posterolateral complex are necessary for the therapeutic decision (operative/conservative). A rupture of the PCL may occur occasionally as a result of a luxation of the knee (reduced spontaneously) before the medical evaluation. A thorough neurovascular examination is essential. Magnetic resonance imaging can be important to the diagnosis of an acute injury, but it is not essential for the choice between operative and non-operative treatment. Arthroscopy has been found to have a high degree of accuracy in the diagnosis of ligament ruptures of the knee, but it is still an operative treatment, so that it can only be used if an operation of repair or reconstruction is planned anyway. Before operative treatment of chronic complex instability, potential osseous abnormalities (varus morphotype) must be revealed; in case of uncertainty, an X-ray control is necessary.

Cross-Sectional Studies↗

MRI assessment of normal ligamentous structures in the craniovertebral junction.

We have established an imaging protocol in order to characterise the normal ligamentous structures in the craniovertebral junction. Thirty volunteers without a history of car accident or head or neck trauma underwent MR imaging with 2-mm-thick proton-density-weighted sections in three orthogonal planes. The alar ligaments were clearly seen in every case and had three different configurations in cross-section: round, ovoid or wing-like. A broadening from lateral to medial in the coronal plane was observed in all cases. The transverse ligament was clearly demonstrated in 26 out of 30 cases. The ligament was flattened where it arched across the dens. Towards the insertions the ligament twisted into an oblique-horizontal orientation. The lower tectorial membrane had a median portion merging with the dura, and a lateral portion separated from it. Between the dens and clivus this membrane either merged totally with dura or was partly separated from it by a thin layer of fat. The posterior atlanto-occipital membrane was clearly demonstrated. It either merged with the dura or was partly or totally separated from it by a fat layer. The anterior atlanto-occipital membrane was inconsistently seen and could not be evaluated. Our refined MR protocol improves the visualisation of the craniovertebral ligamentous structures, and may in the future give new insight into post-traumatic neck disorders up to now poorly understood.

Adult↗

Intraoperatively proven anomalous Struthers' ligament diagnosed by MRI.

A case of median nerve entrapment at the elbow between the supracondylar process and an anomalous insertion of Struthers' ligament is presented. The diagnosis of anomalous insertion of the ligament was made by MRI and confirmed at operation. Struthers' ligament originated as usual from the supracondylar process but did not reach the medial epicondyle of the humerus, inserting instead in the brachial fascia above the epicondyle. The incomplete Struthers' ligament functioned, however, as a complete ligament. It produced symptoms identical to supracondylar process syndrome. Excision of the supracondylar process of the humerus and Struthers' ligament relieved symptoms in this athlete.

Adolescent↗

Trabecular trauma of the talus and medial malleolus concurrent with lateral collateral ligamentous injuries of the ankle: evaluation with MR imaging.

OBJECTIVE: The objective of this study was to elucidate the relationship between lateral collateral ligamentous injuries of the ankle (ankle sprain) and bone bruise (trabecular trauma) of the talus and/or malleoli in the patients with twisting injuries of the ankle. DESIGN: Magnetic resonance studies of the ankle were retrospectively reviewed, focusing on the presence or absence of lateral collateral ligamentous injuries and the location of bone bruise in the talus and/or malleoli. PATIENTS: Thirty-five patients with acute twisting injuries of the ankle were studied. RESULTS AND CONCLUSION: Four patterns of bone bruise were found in 14 patients: (1) bone bruise in the talar dome equivalent to osteochondral fracture in two patients, (2) bone bruise in the posteromedial aspect of the talus and the medial malleolus singly or in combination in four, (3) bone bruise in the anteromedial aspect of the talus in six, and (4) bone bruise with a combination of the second and third patterns in two. The second pattern was associated with tear of the anterior talofibular (ATAF) ligament in all patients and injury of the calcaneofibular (CF) ligament in one out of four. The third and fourth patterns were associated with tears of both ATAF and CF ligaments in all patients. The identification of bone bruise was of value in indicating lateral collateral ligamentous injuries.

Adolescent↗

Computed tomography of gastrocolic ligament: involvement in malignant tumors of the stomach.

BACKGROUND: This study investigated computed tomographic (CT) features and anatomic bases of gastrocolic ligament involvement in malignant neoplasms of the stomach. METHODS: We retrospectively reviewed CT scans of 34 patients known to have gastric malignant neoplasm and gastrocolic ligament involvement. Emphasis was placed on direct invasion, lymph node metastasis, and omental seeding. RESULTS: CT manifestations of gastrocolic ligament involvement included direct invasion (38.2%, 13 of 34), enlargement of lymph nodes (50%, 17 of 34), "smudged" appearance (26.5%, nine of 34), "omental caking" (5.9%, two of 34), cystic mass (2.9%, one of 34), and varices of the omentum (2.9%, one of 34). We also found that gastric carcinoma and gastrointestinal stromal tumor invaded the transverse colon through the gastrocolic ligament in six patients (17.6%, six of 34). CONCLUSION: CT scan is useful for detecting gastrocolic ligament involvement in gastric malignant neoplasm. The imaging features consist of a mass sign, enlargement of lymph nodes, smudged appearance, omental caking, and so on. Gastric malignant neoplasm also may involve the transverse colon through the gastrocolic ligament.

Adenocarcinoma↗

The popliteal region: an anatomical study and a new approach to the tibial attachment of the posterior cruciate ligament.

Surgical treatment of posterior cruciate ligament injuries is gaining more and more importance. The central posterior approach according to Abbott (1945) has been considered a standard, with various complications involved owing to the local anatomic conditions. This study is intended to present a modified dorsomedial approach to the posterior capsule of the knee joint that is better adapted to the anatomic conditions. As a basis, the popliteal region was dissected in 150 knee joints, and the course of the popliteal artery with its branches as well as the bifurcation of the sciatic nerve were identified. The medial joint line served as a reference point. It has been shown that the knee joint arteries and the two sural arteries arose at relatively constant levels. At least one of the meniscofemoral ligaments was found in all of the knee joints examined; the anterior ligament was present in a slightly higher percentage than the posterior ligament. The modified dorsomedial approach to the posterior joint capsule was evaluated in 50 knee joints. Dissection was achieved by blunt division of the medial head of the gastrocnemius muscle, with careful preservation of the proximal vascular supply of that muscle. It was necessary to expose neither the popliteal artery and vein nor the tibial nerve. The tibial attachment of the posterior cruciate ligament could be exposed in every knee. The advantage of the new approach to the posterior cruciate ligament described in this study consists in the preservation of the central neurovascular bundle and the excellent exposure of the tibial attachment.

Aged↗

Discomallear and malleomandibular ligaments: anatomical study and clinical applications.

Phylogenesis, ontogenesis and anatomy show the existence of two discomallear and malleomandibular ligaments, arising from the first branchial arch and uniting the middle ear with the temporomandibular joint and to the mandible. The intra-articular discomallear ligament is the involuted tendon of the lateral pterygoid muscle on the primitive quadrato-articular joint. The malleomandibular ligament is the fibrous remnant of Meckel's cartilage. In the physiology of the temporomandibular joint, the discomallear ligament alone limits the anterior movement of the disc. Its stretching accompanies disco-condylar disunity, hyperlaxity and temporomandibular dislocation. The malleomandibular ligament, wrongly limited to its sphenomandibular part in classic anatomy, has no physiological role. However, it can be responsible for the dislocation of the ear ossicle chain after disarticulation or temporomandibular trauma. These two ligaments do not play any role in otological manifestations in dysfunction of the manducatory apparatus.

Humans↗

Lumbosacral interspinous ligament rupture associated with acute intrinsic spinal muscle degeneration.

The objective of this study was to demonstrate lumbosacral interspinous ligament rupture, with or without related acute intrinsic spinal muscle degeneration. This study consisted of a prospective imaging analysis of consecutive 100 MRI studies in adult patients (mean age 56 years) presenting with low back pain. Alterations from the normal in the inter- and perispinal structures of the spine and perispinal soft tissues (e.g., spinal ligaments, perispinal muscles) were sought based upon studies on young volunteers without low back pain ( n=10; mean age 23 years). Compared with the group without low back pain, many index cases ( n=71, 71%) demonstrated hyperintensity (i.e., sprain or frank ligamentous rupture) of the interspinous ligament(s) on T2-weighted, fat-suppressed MRI studies at one (20 of 71, 28%) or multiple (51 of 71, 72%) levels. Associated intrinsic spinal muscle (e.g., interspinalis, multifidus muscles) degeneration was observed in a minority of cases overall ( n=7, 7%), but was only seen in association with cases also demonstrating interspinous ligament degeneration/rupture (7 of 71, 10%). Lumbosacral interspinous ligament sprain or frank rupture, as well as related acute-subacute autotraumatic intrinsic spinal muscle rupture/degeneration, may be overlooked by many observers if fat-suppressed, T2-weighted MRI is not acquired. These musculoligamentous alterations are on occasion the only abnormalities recognized on MRI of the lumbosacral spine and may theoretically be sources of low back morbidity that potentially may respond to specific therapy. Because this study was an observational one, based solely upon medical imaging, future research must focus upon the correlation of the relevance of these findings with an age-matched asymptomatic control group and longitudinal clinicoradiologic therapeutic trials.

Humans↗

Sacrospinous ligament fixation for vaginal vault prolapse.

INTRODUCTION: To assess intra- and postoperative complications and to look for long term follow-up results in women with sacrospinous ligament fixation. METHODS: Between 1988 and 1999, 200 women (mean age 59.8 years, range 33 to 83 years) underwent vaginal unilateral sacrospinous ligament fixation. 172 patients had had prior hysterectomy. In 28 patients concomitant hysterectomy and sacrospinous ligament fixation was performed. Sacrospinous ligament fixation was combined with the following procedures: 109 enterocele repairs (54.5%), 88 anterior colporrhaphies (44%), 57 reconstructions of urogenital diaphragma (28.5%) and 23 posterior colporrhaphies (11.5%). Additional Burch colposuspension and a Stamey procedure were carried out in 7 (3.5%) and 15 (7.5%) patients, respectively. RESULTS: All 200 patients were analysed for intra- and postoperative complications. Urinary tract infection (n = 16, 8.0%), temporary irritation of the sciatic nerve (n = 15, 7.5%), temporary partial ureteral obstruction (n = 11, 5.5%) and blood loss less than 400 ml (n = 7, 3.5%), occurred in the postoperative phase. Long-term data (range from 6 months to 9 years, mean 4.8 years) exist for 123 patients. 119 were completely cured without any signs of urinary incontinence and prolapse. At follow-up 4 patients (3.25%) showed recurrent vaginal vault prolapse. Recurrent cystoceles, rectoceles, enteroceles, were found in 10 cases (8.1%), one (0.8%) and one (0.8%), respectively. Two patients with complete recurrence of vaginal vault prolapse successfully underwent colpectomy and repeated sacrospinous ligament fixation, respectively. CONCLUSIONS. Sacrospinous ligament fixation is an effective and safe procedure with a low recurrence and complication rate.

Adult↗

Phosphatidylinositol-dependent bond between alkaline phosphatase and collagen fibers in the periodontal ligament of rat molars.

Alkaline phosphatase (ALP) is anchored to the outer leaflet of the lipid bilayer via phosphatidylinositol (PI) and ALP activity has been localized in the plasma membrane of numerous tissues. In the periodontal ligament ALP activity is found in the collagen fibers in addition to the plasma membrane of the osteoblasts and fibroblasts. In this study, we examined the distribution of ALP activity in the periodontal ligament of rat molars and also examined whether the bond between ALP and collagen fibers is dependent on PI by using phosphatidylinositol-specific phospholipase C (PI-PLC). ALP activity was distributed in the periodontal ligament. The activity mirrored the distribution of collagen fibers in the periodontal ligament. Cytochemical analysis also demonstrated that ALP activity was located not only in the plasma membrane of fibroblasts, but also in the collagen fiber bundles and fibrils in the periodontal ligament. After treatment with PI-PLC, the loss of ALP activity in the periodontal ligament was observed histochemically, and the loss of ALP activity in the fibroblasts as well as in the collagen fiber bundles and fibrils was observed cytochemically. These results strongly indicate that the bond between ALP and the collagen fibers is also dependent on PI.

Alkaline Phosphatase↗

Topographic relations between the neural and ligamentous structures of the lumbosacral junction: in-vitro investigation.

Transient or persistent alterations in the L5 lumbar nerve root have been described as a complication after the reduction of spondylolistheses. In a retrospective analysis of our own patients, we observed a higher incidence of transient motor and sensomotor deficits after single-sitting anatomic correction of May-erding grade IV anterolistheses and spondyloptoses. These findings are consistent with those of other authors. The deficits pertained to muscles in the innervation range of the L5 nerve root, without there being any evidence of intradural root damage or nerve compression. In vitro studies have shown distraction and translation of the nerve root to be pathogenetically relevant mechanisms, leading to damage during intraoperative reduction. Additional alteration of neuronal structures may be caused by ventral parts of the iliolumbar ligament complex during the reduction maneuver. In order to reveal extradural constrictions of the L5 nerve root that might predispose towards intra- or perioperative damage, we examined anatomic specimens to determine the course and neighboring relationships of the lumbosacral plexus, especially in relation to pelvivertebragenic ligamentous connections. In addition to the morphologic considerations, we conducted translation tests, which were designed to simulate changes in shape and size of the epineural layer, as well as in vitro measurements of the resulting pressure on the nerve. In addition to a range of variations in the attachment of the iliolumbar ligament complex, which was always located dorsally to the nerve roots, we found a ligamentous connection formed by connective tissue between the sacrum and the fifth lumbar vertebral body on the caudal margin of the ligament apparatus in 14 out of 30 specimens. Its course was constantly ventral to the L5 nerve root, which was also adherent to the periosteum of the sacrum distal to this constriction in one-fifth of the specimens. The average pressure exerted on the nerve root during the distraction and translation process was over 30 mmHg in the area of this lumbosacral ligamentous connection, at a distance of greater than 20 mm. When the translation distance was further increased, perineural fatty tissue was discharged, due to increasing perineural pressure.

Aged↗

Biomechanical functions of the iliolumbar ligament in L5 spondylolysis.

Abiomechanical study of the functions of the iliolumbar ligament in L5 spondylolysis was performed. Five fresh cadaveric specimens were used. The bilateral ilia and sacrum were fixed. Four kinds of pure moments (10 Nm) were applied to the specimens at the top (L4) vertebra: flexion, extension, and right and left axial rotations. The three-dimensional position of the L5 vertebra was measured after serial transections in: (1) the intact condition; (2) bilateral pars interarticulares of L5 transected; (3) anterior bands of the iliolumbar ligaments transected; and (4) posterior bands of the iliolumbar ligaments transected. In L5 spondylolysis, flexion and axial rotation of L5 on S1 are significantly regulated by the anterior and posterior bands of the iliolumbar ligaments (especially by the posterior bands of the ligaments). The integrity of the ligament may determine the stability of the lumbosacral junction and the amount of forward slipping of the L5 vertebra.

Aged↗

Laminar configuration of the transverse carpal ligament.

We investigated the laminar configuration of the transverse carpal ligament, using 77 hands from 44 donated cadavers. According to the running directions and attachments of the fiber bundles composing the ligament, we identified four basic bundle patterns: proximal transverse, distal transverse, radial oblique, and ulnar oblique. Although these patterns often coexisted and the bundles were somewhat intermingled, a specific pattern was very evident in several laminae. Laminae with the distal transverse bundle pattern were the thickest and were reinforced by additional fibers which originated from the palmar aponeurosis and were deeply inserted into the lamina. Based on the laminar configurations of the superficial and deep layers and their composite fiber bundles, we classified the ligaments into four types. Type I, in which distal transverse and ulnar oblique laminae predominated in every layer, was the most common (44.2%), while another large group (41.6%) exhibited type II ligaments, comprising distal transverse and ulnar oblique laminae in the superficial layer and proximal transverse and radial oblique laminae in the deep layer. Thus, in almost half of the patients (type II), the strong distal transverse lamina is likely to be excised during the final step of endoscopic carpal tunnel release because of its superficial localization. This could be a major reason for the frequent occurrence of incomplete release. Moreover, the almost universal superficial ulnar oblique bundle pattern (observed in type I, II, and III ligaments), predisposes to scarring, which may cause radial shifting of the ulnar neurovascular bundle and may affect the palmar branch of the median nerve. We conclude that the interindividual variability seen in the results of endoscopic carpal tunnel release, including minor complications, depends partly on configurational variations in the laminar arrangement of the transverse carpal ligament.

Aged↗

Alteration of nerve growth factor-receptor expression in the periodontal ligament of the rat during experimental tooth movement.

This pilot study deals with the initial responses of neural elements showing nerve growth factor-receptor (NGFR) immunoreactivity in the periodontal ligament of rats to orthodontic forces. The animals were killed at intervals of 1, 2, 6, 12 h and 1, 3, 5, 7 days after the insertion of elastic bands between the maxillary first and second molars. Serial frozen sections, prepared from each animal, were processed immunohistochemically to demonstrate NGFR, after which the periodontal ligament of the mesial root of the maxillary second molar was examined microscopically. In control sections, NGFR-positive neural elements were predominantly distributed at the apex of the bony socket on the distal side of the periodontal ligament. After 1 h of tooth movement, NGFR positively-stained nerve fibres tended to disappear slightly in both the intermediate and coronal regions of the distal periodontal ligament. By the third day of tooth movement, the periodontal ligament nerve fibres showed more intense NGFR-immunoreactivity; thick, positively stained nerve fibres were recognized on the distal side in which active bone remodelling was occurring, and a few of these fibres were densely distributed around blood vessels or near Howship's lacunae. The distribution of NGFR-positive neural elements on the mesial side increased at 5 days of tooth movement. Finally, at 7 days of tooth movement, staining intensity for NGFR appeared to decrease. These findings demonstrate that an alteration in the distribution and the intensity of immunoreactive staining for NGFR in the periodontal ligament is associated with the bone remodelling induced by orthodontic tooth movement.

Animals↗

The effect of velocity of loading on the biomechanical responses of the periodontal ligament in transverse sections of the rat molar in vitro.

Stress-strain relations of this ligament in transverse sections of the mandibular first molar were examined over a wide range of velocities of loading from 1 to 10(4) mm/24 h. With increasing velocities, the maximum shear stress, tangent modulus and failure strain-energy density increased but the maximum shear strain decreased. The mechanical responses at the highest velocity for the molar ligament were compared with those previously found for the incisor ligament. Mechanical strength, stiffness and toughness were greater for the molar than for the incisor ligament; the molar ligament therefore has more extensible fibres or a different fibre arrangement. Comparison of the mechanical responses at the slowest velocity suggests that, though the stress level was greatly reduced (presumably because of stress relaxation), the fibre components of the molar ligament still reacted at this velocity. It is also suggested that the differences in the ratios of the mechanical measures in 10(4)-1 mm/24 h between the two types of teeth are due partly to their different periodontal fibre architectures.

Alveolar Process↗

Comparison of material properties in fascicle-bone units from human patellar tendon and knee ligaments.

The fascicle material properties in bone-fascicle-bone units were determined for the anterior and posterior cruciate ligaments (ACL, PCL), the lateral collateral ligament (LCL) and the patellar tendon (PT) from three young human donor knees. Groups of fascicles from each tissue were isolated with intact bone ends and failed at a high strain rate in a saline bath at 37 degrees C. In each knee tested the load related material properties (linear modulus, maximum stress and energy density to maximum stress) for the patellar tendon were significantly larger than corresponding values for the cruciate and collateral ligaments. Bundles from different ligaments in the same knee were similar to each other in their mechanical behavior. In addition, no significant differences were present in the maximum strains recorded for any of the four tissue types examined. The results presented have implications in studies of ligament injury. They are also important in the design and use of synthetic and biological ligament replacements and in tissue and whole knee modeling.

Adult↗

Effects of knee flexion on the structural properties of the rabbit femur-anterior cruciate ligament-tibia complex (FATC).

Many studies have been conducted to determine the biomechanical properties of the anterior cruciate ligament (ACL). The method of holding the femur-ACL-tibia complex (FATC) test specimen, the strain rate applied, the angle of knee flexion and the direction of the applied loads have an important effect on the outcome. It is felt that the tensile properties and strength of the ligament should be measured by applying the tensile force along the axis of the ligament. A versatile clamp was designed to accomplish this purpose. Fifty-seven rabbit knee specimens were tested at angles of flexion of 0 degrees, 30 degrees or 90 degrees. In addition, a comparative study of 25 pairs of rabbit legs were performed, whereby loading was either along the ligament or along the tibial axis. Cyclic hysteresis, ultimate load, energy absorbed, and stiffness were determined. The ultimate load values for the FATC decreased with increased knee flexion for those loaded along the tibial axis, while no such change was detected for FATC tested along the ligament axis. Other structural properties measured followed similar trends. It is concluded that the structural properties of the rabbit FATC change minimally with knee flexion (from 0 to 90 degrees) when loaded along the ligament axis, but decrease significantly with knee flexion when loaded along the axis of the tibia. Therefore, the data obtained in this field of study can be compared only if the direction of loading with respect to the ACL is similar.

Animals↗

In situ mechanical behavior of posterior spinal ligaments in the lumbar region. An in vitro study.

The posterior ligaments: ligamentum flavum, articular, interspinous and supraspinous ligaments of twenty five fresh cadaveric intervertebral segments, from T11-T12 to L4-L5, extracted from fourteen spines were tested in tension. A progressive dissection method was used, that is, each segment was tested after first resecting the disk with the ligaments intact and a force-elongation curve obtained. Then one ligament was cut and the test repeated, and so on. The most restrictive ligament was found to be the ligamentum flavum followed by the articular, interspinous, and supraspinous ligaments.

Aged↗