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Results for “CAT-SCRATCH DISEASE”

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PubMed1985

[Mycobacterium chelonei cutaneous infections. General review apropos of a case].

Mycobacterium chelonei is a facultative pathogen which exists as a saprophyte in the environment and rarely produces clinical manifestations in humans. We describe a 62-year-old woman, long-term treated with low-dose steroids for severe asthma, who presented sporotrichoid-like lesions on one leg. These lesions appeared two months after a cat-scratch and were present for six months. Histological examination showed acute inflammation with polymorphonuclear infiltration without tuberculoid granuloma nor caseation necrosis. Ziehl-Neelsen stains were negative. Mycobacteria were found by direct examination and Mycobacterium chelonei chelonei was identified by culture. Treatment with isoniazid, rifampicin and ethambutol was given for one month and followed by complete resolution of the lesions, though each of these antibiotics was not effective in vitro. The literature about Mycobacterium chelonei infections is reviewed and the role of the antibiotherapy in clinical recovery is discussed.

Asthma↗
PubMed1993

Neurosurgical management of the acquired immunodeficiency syndrome. An update.

A retrospective review of a 24-month experience on the neurosurgical service at a large metropolitan hospital identified 33 patients with the acquired immunodeficiency syndrome (AIDS) who underwent diagnostic or therapeutic procedures. Intracranial mass lesions unresponsive to empiric medical therapy for presumed Toxoplasma gondii encephalitis underwent diagnostic biopsy in 22 patients: primary lymphoma was identified in 10 (45%) of these patients, and biopsy led to a treatable diagnosis in 16 of the 22. Patients with lymphoma were significantly more likely to have a single mass lesion than those with other diagnoses. The remaining 11 patients had a wide variety of neurologic disorders, including multiple strokes and transverse myelitis, aspergillous fungal infection of the base of the skull, primary lymphoma of the spinal cord, cat-scratch fever of the spine causing painful radiculopathy, hydrocephalus associated with cryptococcal meningitis, and progressive inflammatory peripheral neuropathy. Two patients had lymphoma within the subarachnoid space. Three patients with well-controlled AIDS underwent elective neurosurgical therapy for intractable radiculopathies due to herniated lumbar discs in 2 and cervical spondylosis in 1. Current treatment strategies in AIDS appear to have limited the need for brain biopsy, but the spectrum of neurologic disorders has broadened, requiring continued participation by neurologists and neurosurgeons. With improved long-term survival, the elective treatment of non-AIDS-related neurologic disorders in selected patients may be appropriate.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Lymphogranuloma venereum].

Lymphogranuloma venereum (LGV) or Nicolas-Favre disease is a sexually transmitted disease (STD) which occurs throughout Africa and mostly affects men. The true prevalence of LGV in tropical countries is not known. The most prominent clinical signs of LGV are inguinal and rectal syndrome, with the inguinal syndrome being the most frequent sign in men. Inguinal adenitis is mostly unilateral. The glands are at first hard and tender but soon become matted together. Fistulae may develop within the glands in swollen areas, some of which break through the reddish-purple overlying skin in chronic cases. The groin fold often separates the glands into upper and lower groups. The rectal syndrome is not common in African patients. It is the second most common sign of LGV, but is not specific to this STD. Fluctuant, discharging, painful and often unilateral adenitis with or without a history of primary ulcerative lesion is most likely to be confused with cat-scratch fever, pyrogenic infections, tuberculosis, adenitis caused by syphilis, mycetoma and histoplasmosis. The diagnosis of LGV should be confirmed by culture, which can be used to isolate the L strain of Chlamydia trachomatis or by PCR (polymerase chain reaction). The histological features of adenitis and rectal lesions are not specific. Tetracycline antibiotics are the most effective treatment for LGV.

Adult↗