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PubMed2006

[Ruptured aortoiliac aneurysm with AV-fistula].

HISTORY AND ADMISSION FINDINGS: A 65-year-old man presented an acute swelling of the left leg as the main sign. A pulsatile bruit could be auscultated over the abdomen. INVESTIGATIONS: Doppler ultrasound suggested an aortic aneurysm with fistula. Dynamic bolus-triggered computed tomography demonstrated an aortoiliac aneurysm with a fistula into the confluence of the common iliac veins. TREATMENT AND COURSE: An aorto-iliac graft was inserted surgically and and the patient recovered well. CONCLUSION: In patients with an acute swelling of a lower limb an aorto-iliac aneurysm, though a rare cause, should be considered.

Aged↗
PubMed1997

The arterialized antebrachial skin flap for hand reconstruction.

The authors present 20 microvascular flaps based on arteriovenous perfusion, harvested from the distal anterior forearm, and configured in three different designs. Indications were small palmar, dorsal, and commissural defects, when other conventional procedures were not available; problematic cases of open reduction internal fixation with skin defect; and when aggressive rehabilitation was needed. The follow-up varied between 6 and 28 months. Some degree of vascular congestion was observed in 100 percent of the flaps, and those changes were classified in a progressive form. Coverage was judged as stable, thin, and pliable in 75 percent of the cases in the series; aggressive rehabilitation was started promptly in all cases where this was possible. On average, an additional 2.4 hr were required for the original procedure. This flap demands little technical expertise for any microsurgical surgeon, and does not sacrifice any important donor vessel. The flap should not be followed-up by conventional monitoring methods instead, simple palpation of the pulse, Doppler auscultation, or PPG are required.

Adult↗
PubMed1991

[Gas embolism with cardiac arrest during hysteroscopy. A case report on 3 patients].

Hysteroscopy and laparoscopy are relatively non-invasive methods routinely employed in the investigation of infertility. The danger of air embolism during these procedures was recognized early, and carbon dioxide was substituted for air since it is more readily soluble in blood. In this report we describe 3 cases of circulatory collapse and cardiac arrest in healthy young women during routine hysteroscopy (out of a total of 62 patients during the period 1989-1990) which were most probably caused by massive carbon dioxide embolism. Premedication was with oral diazepam 10 mg. Anesthesia was induced with 0.1 mg fentanyl, 2.5 mg droperidol and 100 mg methohexital (100 mg propofol in one case). Intubation was facilitated with 2 mg pancuronium and 50-100mg succinylcholine. Anesthesia was maintained with nitrous oxide 66% and halothane. Ventilation was controlled with a tidal volume of 10 ml per kilogram body weight at a rate of 10 per minute. Monitoring included ECG, automated non-invasive blood pressure, capnometry, pulse oximetry and body temperature. Anesthesia was uneventful prior to insufflation. In each case the signs and symptoms began approximately 5-8 minutes after the start of insufflation and consisted of an initial tachycardia rapidly followed by ventricular dysrhythmias, bradycardia and cardiac arrest. The end-tidal CO2 decreased during the tachycardic phase and prior to asystole. The patients were cyanotic with engorged jugular veins. Resuscitation with closed chest heart massage and intravenous epinephrine or orciprenaline was successful in every case. The typical "mill wheel phenomenon" of gas embolism was audible on auscultation after heart activity had returned, but disappeared after about 5 minutes.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1989

[Transthoracic color Doppler echocardiography in the diagnosis of insufficiency of heart valve prostheses. A comparison with conventional Doppler sonography].

Color-coded and conventional pulsed wave/continuous wave Doppler detection of valvular or paravalvular regurgitation in 59 patients with 67 cardiac valve prostheses were compared; 21 patients had known regurgitation determined by auscultation. Analysis of the color-coded Doppler findings was made from videotape and blinded as to patient identity and clinical findings. Conventional Doppler Sonography detected 36 instances of aortic and 3 of mitral prosthetic regurgitation. Color-coded Doppler investigation detected 27 instances of aortic and 1 of mitral prosthetic regurgitation resulting in a sensitivity of 72% and specificity of 100% as compared to conventional Doppler sonography. All 21 patients with a regurgitant murmur had pathological conventional Doppler findings, but 3 of them did not show regurgitant flow in the color-coded Doppler examination. The apical four chamber view contributed most to the colour-coded Doppler detection of regurgitant flow, followed by the parasternal long axis view.

Adult↗
PubMed1995

Aortic dissection after aortic valve replacement. Report of a case with an aortocameral fistula.

A 58-year-old Japanese woman who had a history of aortic valve replacement for congenital bicuspid valve, was admitted for investigation of facial edema and of pulselessness of the right leg. Physical examination disclosed the patient suffering from a superior vena cava syndrome. On auscultation, a continuous murmur was heard at the left lower sternal border. Computed tomographic scans revealed aortic dissection extending from the ascending aorta to the bifurcation. Echocardiography showed an intimal flap in the dilated ascending aorta, but not abnormal blood flow from the aorta to the right atrium was detected. Cardiac catheterization and aortography, however, allowed a correct diagnosis of aortic dissection with fistula to the right atrium and with obstruction of the right common iliac artery. The patient received emergency aortic root replacement and reconstruction of the coronary arteries and then recovered uneventfully.

Aortic Dissection↗
PubMed1994

False aneurysm of the ascending aorta with fistula to the right atrium. Noninvasive diagnosis by computed tomographic scan and two-dimensional echocardiography with successful repair.

A 57-year-old Japanese man presented with symptoms of congestive heart failure 9 years after aortic valve replacement. On auscultation, a continuous murmur was heard at the left lower sternal border. Chest radiograph showed moderate cardiomegaly and a widened upper mediastinum. Computed tomographic scans showed a dilated ascending aorta, in which there was no intimal flap, and also showed a large mass which compressed the right atrium. Two-dimensional Doppler echocardiography revealed abnormal continuous blood flow directed from the dilated ascending aorta to the right atrium and no periprosthetic leak. At operation, a false aneurysm of the ascending aorta which originated from the aortotomy suture line and a fistula from the aorta to the right atrium were confirmed. The fistula was closed with pledgeted sutures, and the ascending aorta was replaced with a collagen-coated double woven velour dacron graft. The patient recovered uneventfully. Computed tomographic scan and two-dimensional echocardiography are complementary techniques for reliable non-invasive assessment of the complexity of an aortic aneurysm.

Aneurysm, False↗
PubMed1996

[Intensive fetal monitoring sub partu or the quality of clinical research].

The first prospective randomised study comparing intermittent auscultation of the fetal heart rate with continuous electronic monitoring during labour and delivery, which showed an increased rate of Caesarean sections in the group with electronic monitoring without significant benefit to the newborn, met with great scepticism on the part of many perinatologists. Meanwhile, 8 additional prospective randomised trials confirmed the first results. The debate concerning the benefit and need of fetal monitoring during labour has even generated doubts regarding the need for, and benefit of, prospective randomised studies. Various study designs have been used in clinical research to test new diagnostic and therapeutic methods. Observational studies generally provide first impressions which are then strengthened by comparison of study patients with historical controls from the time before the introduction of the new method. Retrospective or prospective matched pair studies may also support the initial hypothesis. The gold standard of all designs is undoubtedly the prospective randomised trial. A double blind randomisation should be performed if feasible, in which neither the subject concerned nor the investigator are aware as to how the patient has been assigned. Only by a prospective randomised study design, known and unknown variables which may affect the outcome can be controlled and will not interfere with the assessment of the new method, since they will appear in equal measure both in the study and in the control group. In view of the rapid development of the discipline of perinatal medicine, with the evolvement of manifold new diagnostic and therapeutic methods, a critical assessment of these methods using the principle of the prospective randomised study design, is imperative. The clinical investigator has a moral obligation towards the patient to select that method which is of maximum benefit with minimum risk to the patient. In addition, in view of the drastic need for controlling expenditure in health care, it is in the interest of society that the use of methods with questionable benefit or with an unreasonable cost-benefit ratio is avoided by means of critical assessment and selection.

Asphyxia Neonatorum↗
PubMed1998

[Right ventricular thrombus after pacemaker implantation in a patient with secondary antiphospholipid syndrome].

HISTORY AND ADMISSION FINDINGS: An 85-year-old woman was admitted because of frequent syncopes. She also reported slight weight loss, cough and dyspnoea. Chest auscultation revealed slight stridor and a cardiac arrhythmia, with an irregular ventricular rate between 120 and 140 beats/min. INVESTIGATIONS: She had a thrombocytopenia (96 platelets/nl), and the ECG and long-term monitoring showed a tachyarrhythmia with atrial fibrillation, a bifascicular block (left anterior hemiblock and right bundle branch block), as well typical signs of sick-sinus syndrome with short periods of bradycardic sinus rhythm and pauses of up to 6 s on rhythm change. Echocardiography indicated moderately reduced left ventricular function. Chest radiogram revealed tracheal narrowing by a retrosternal goitre. No evidence of tumour was found on bronchoscopy. DIAGNOSIS, TREATMENT AND COURSE: A VVI pacemaker was implanted. When the platelet count dropped to 30/nl idiopathic thrombocytopenic purpura was suspected, but administration of high doses of corticoids and immunoglobulin was without effect. Another echocardiogram, performed because of chest pain suspicious of pulmonary embolism, revealed a large bowl-shaped right ventricular thrombus with floating parts. Demonstration of anticardiolipin antibodies established the diagnosis of antiphospholipid syndrome (APLS), thought to be secondary to thyroid cancer suspected from the computed tomography. The patient died 2 months later from recurrent pulmonary embolism and progressive liver failure. Autopsy revealed a not previously diagnosed tracheal carcinoma with metastases to the thyroid, as well as haematogenous metastatic foci within the right ventricular thrombus. INTERPRETATION: In case of thrombocytopenia of uncertain aetiology APLS should be included in the differential diagnosis, even in the absence of any early or acute thrombosis. If anticardiolipin antibodies and/or lupus anticoagulant are demonstrated, malignant neoplasm should be considered in addition to autoimmune disease.

Aged↗
PubMed1998

[Primary pulmonary plasmacytoma. Case report of a rare lung tumor].

HISTORY AND CLINICAL FINDINGS: A 45-year old man, suffering from dry cough without haemoptysis, was admitted for evaluation of pulmonary changes of uncertain aetiology. A chest radiograph and computed tomography (CT) had shown a large space-occupying lesion in the left hilus. His general condition was poor and he had resting dyspnoea and stridor. On auscultation of the lung there were decreased breath sounds and dry rales over the left and vesicular breathing over the right lung. INVESTIGATIONS: CT revealed a 7.0 x 6.0 cm space-occupying lesion in the left hilus and ipsilaterally a tumour in the dorsolateral lower lobe surrounding the left lower lobe bronchus. Initial bronchoscopy showed this bronchus to be involved in the tumour process. Biopsy demonstrated monomorphic proliferating plasma cells which on immunochemical testing showed selective staining to lambda-light chains and immunoglobulin G. The first serum electrophoresis was unremarkable, but a later repeat discovered a small amount of paraprotein for IgG-lambda type. Bence-Jones protein was demonstrated in the urine. On the basis of these findings an extramedullary plasmacytoma of the lung (PPP) was diagnosed. TREATMENT AND COURSE: At first the patient was given i.v. chemotherapy, and to prevent a threatening bronchial occlusion oral dexamethasone was given. Pericardial effusion and recurrent retention pneumonia developed. 6 month after onset of symptoms radiotherapy was begun and the tumour became markedly smaller. CONCLUSION: PPP should be included in the differential diagnosis of pulmonary space-occupying lesions even when initial serum protein electrophoresis is negative for monoclonal paraproteinaemia. Pericardial effusion may be caused by pulmonary involvement of the plasma cell tumours.

Biopsy↗
PubMed1998

[A case of Carney complex].

HISTORY AND CLINICAL FINDINGS: For some months a 57-year-old woman had noted increasing shortness of breath, associated in the last few weeks with undirected vertigo and several brief periods of lost consciousness. She was finally admitted because of additional central facial paresis. On auscultation a high-frequency systolic murmur was heard over the apex and a discrete diastolic murmur over Erb's point. There were numerous facial freckles and three cutaneous myxomas. INVESTIGATIONS: Echocardiography revealed irregular tumours throughout the left atrium and a large broad-based one prolapsing through the mitrale valve in diastole. Computed tomography demonstrated a 6 x 6 cm tumour in the left lower abdomen, probably arising from the left ovary, and a second 3 x 3 cm presacral tumour. TREATMENT AND COURSE: At cardiac surgery four tumours were found in the left atrium and resected: histologically they were benign myxomas. Removal required extensive resection in the area of the interatrial septum and the atrial wall, resulting in 2 degrees AV block for which a VDD pacemaker was implanted. CONCLUSION: Atrial myxomas may be the cardinal sign of the Carney Complex, an autosomal dominant syndrome with cutaneous myxomas, myxoid abdominal tumours, hormone-producing tumours in the testicles, adrenal cortex or hypophysis, schwannoma as well as lentigines. For this reason, further tumours should be looked for if freckles and/or cutaneous tumours are found in association with an atrial myxoma. The patient and family should be informed about the genetic aspects.

Dyspnea↗
PubMed1999

[Percutaneous transvenous mitral valvuloplasty in a pregnant patient. Successful treatment of severe mitral stenosis].

HISTORY AND CLINICAL FINDINGS: A 31-year-old woman presented in the 25th week of pregnancy with ankle and pretibial oedema and increasing dyspnoea, ultimately in class IV (New York Heart Association classification). There were fine rales on auscultation and dullness on palpation over both lung bases. The heart rate was regular at 110/min. The first heart sound was very loud, and there was a mitral opening snap and a loud diastolic murmur maximal, over the cardiac apex. INVESTIGATIONS: The ECG showed sinus rhythm at a rate of 110/min, left axis deviation, incomplete right bundle branch block and P biatriale, but no other abnormalities. Echocardiography revealed biatrial enlargement and an enlarged right ventricle as well as pulmonary systolic hypertension of 100 mm Hg. Doppler sonography demonstrated severe mitral stenosis with a calculated mitral opening area of 0.9 cm2. DIAGNOSIS, TREATMENT AND COURSE: The symptoms improved only slightly under conservative drug treatment. The mitral valve changes, as noted sonographically, met the criteria for percutaneous transluminal balloon mitral valvoplasty (PTBMV), which was successfully performed. Afterwards the mitral opening area was 2.6 cm2 and pulmonary artery pressure gradually became normal. She was delivered without complication of a healthy child in the 39th week of pregnancy. CONCLUSION: PTBLMV is a relatively low-risk treatment in pregnant women with symptomatic mitral stenosis.

Adult↗
PubMed1999

[Isolated thrombosis of the vena profunda femoris as the source of embolisms. A diagnosis easy to supply using duplex sonography].

HISTORY AND ADMISSION FINDINGS: A 79-year old man was admitted because of increasing dyspnoea. At physical examination he had dyspnoea at rest, auscultation of the lung was unremarkable and there was no peripheral oedema or unilateral swelling of a leg to suggest venous thrombosis. INVESTIGATIONS AND DIAGNOSIS: Chest radiogram was unremarkable. Perfusion scintigraphy of the lung, performed to exclude pulmonary embolism, revealed several defects typical of emboli. Duplex sonography revealed an isolated thrombosis of the left profunda femoris vein, while the deep veins were patent. TREATMENT AND COURSE: Anticoagulation with heparin followed by phenprocoumon rapidly improved the symptoms and the patient was discharged after 10 days. CONCLUSION: Thrombosis of the profunda femoris vein can cause clinically relevant pulmonary embolism. While this vessel cannot be visualized by phlebography, duplex sonography easily establishes the diagnosis and should be used routinely in the investigation of suspected thrombosis of the leg veins.

Aged↗
PubMed1994

[Pneumothorax in laparoscopic cholecystectomy (II)].

This case report deals with pneumothorax during elective laparoscopic cholecystectomy in a young woman with no history of severe pulmonary disease. After inflating the capnoperitoneum, pulse oximetry and capnography raised suspicion of pneumothorax whereas the physical examination showed no irregularities. Surgical drapes provided a lack of information from percussion and auscultation. Changing respiratory parameters including the use of pressure-controlled ventilation in absence of tension pneumothorax enabled sufficient ventilation until the insertion of a chest tube. There were no further postoperative complications. Pulse oximetry, capnography and relaxometry proved helpful in monitoring. There may be a benefit from the use of pressure-controlled-ventilation in certain situations, if all changes in volume-controlled-ventilation fail.

Carbon Dioxide↗
PubMed1996

[The Eustachian tube and its role in the history of otology. Images from the history of otorhinolaryngology, presented by instruments from the collection of the Ingolstadt German History Museum].

Even in ancient times the existence of an open pathway between the ear and the respiratory tract was assumed. Up to the middle ages, however, Aristotle's idea that the air in the ear is an innate part of the body prevailed. The first anatomical description of the tube was given by Eustachius (1563). He still adhered to the concept of "innate air" and regarded the tube only as a pathway for draining pathological matter from the tympanic cavity. Duverney (1683) realized that an important function of the tube was replacing and adjusting the pressure of the air in the tympanic cavity. He thought that the tube is permanently open, thus offering a vent to the air, when the tympanic membrane is moving inwards and outwards. Valsalva (1704) discovered a muscle for opening the tube, and he presumed that in hearing this muscle would come into action. He described the maneuver that is named after him as a method to expel pus from the tympanic cavity into the external auditory canal. E.G. Guyot, a postmaster in Versailles, was the first to try catheterization of his own Eustachian tube via the mouth. Cleland (1741) inserted the catheter via the nose, and Wathen (1756) after studies on corpses described in detail the technique how to carry out this procedure. The therapeutic application of Eustachian catheterization as practiced by physicians such as Itard (1821) centered around irrigation with water and medications as well as inflation of various fumes. Deleau (1836) later advocated a douche of pure air and, in analogy to the auscultation of the lung, described the different noises that could be perceived during this procedure. Numerous models of pumps were constructed for this air douche, which became one of the most widely used therapeutical means in otology. There were also lethal incidents caused by cutaneous emphysemata. Toynbee realized that at rest the tube is closed and that there is a constant absorption of air in the tympanic cavity. The tube would be opened only by the act of swallowing and air would then be allowed to enter to equalize pressure. He believed that the maneuver he described, namely swallowing while the nostrils are closed, would produce a positive pressure in the tympanic cavity. He died when he applied these maneuvers in order to press fumes of chloroform or cyanic acid into his ears to treat his tinnitus. Politzer could demonstrate that after Toynbee's maneuver the middle ear is left with a negative pressure, and consequently, in 1861-63, he devised his own method for actively inflating the middle ear. The history of these events is described in detail and illustrated by a number of figures and anecdotal episodes.

Eustachian Tube↗
PubMed1995

[Effects of surgical therapy of obstructive snoring on swallowing and voice quality].

The efficacy of uvulopharyngopalatoplasty (UPPP) in treating obstructive snoring has been reported from many centers. The reduction of uvula and soft palate may result in palatal incompetence. We examined 23 patients undergoing UPPP pre- and postoperatively and found a slight preoperative hypernasality in three patients. None of our patients had problems with swallowing. During the first week postoperatively, most of the patient had hypernasality and noted a nasal escape of liquids. Three to four months after surgery, three patients still had problems swallowing. All 21 patients seen during the last follow-up examination had a nasal escape of air detected by auscultation in at least one of the tests. Two patients had an audible hypernasality. Two patients could not pronounce the letters any more. More than one year after surgery, palatal incompetence was no longer detectable.

Deglutition Disorders↗
PubMed1987

[Supraventricular tachycardia of the fetus in the 3d trimester of pregnancy following persistent supraventricular extrasystole].

Persistent supraventricular extrasystoles are antepartally, intrapartally and postpartally the most frequent form of arrhythmias, and do not cause fetal congestive heart failure (hydrops fetalis). The premature beats often disappear spontaneously prenatally, but in most cases within the first two weeks of life. The extremely rare observation of the occurrence of a supraventricular tachycardia in the 37th week of gestation in a fetus with persistent supraventricular extrasystoles from the 20th week of gestation onward and with a postnatally diagnosed Wolff-Parkinson-White syndrome is described. Because of the importance of this complication of supraventricular extrasystoles (a supraventricular tachycardia of the fetus can cause a cardiac failure with hydrops fetalis and eventually intrauterine death), it is important that all fetuses with supraventricular extrasystoles be closely monitored by frequent observation of the fetal heart rate using ultrasound (M-mode-echocardiography), cardiotocography and auscultation. Postpartally a cardiologic examination of these newborn infants is necessary, particularly in order to exclude the presence of a preexcitation.

Cardiac Complexes, Premature↗
PubMed1996

[Coarctation of the abdominal aorta].

HISTORY AND FINDINGS: When a 27-year-old woman went to her general practitioner with symptoms of acute gastroenteritis he noted a paraumbilical murmur on auscultation. There were no symptoms of intermittent claudication or abdominal angina. All peripheral pulses were easily palpable and bilaterally equal, and there were no vascular murmurs. Physical examination and blood pressure (140/70 mm Hg bilaterally) were normal. INVESTIGATIONS: Biochemical tests gave no indication of inflammatory disease. Oscillography showed a brief decrease in amplitude after muscular exertion, predominantly of the thigh. Posterior tibial systolic pressure was 20 mm Hg lower than radial pressure on the right, 25 mm Hg on the left. Colour Doppler sonography demonstrated elongated and looping coarctation of the abdominal aorta. TREATMENT AND COURSE: As the patient had no symptoms only regular follow-up was indicated. There have been no symptoms for 27 months and no progression of the coarctation. CONCLUSION: In young patients with the described symptoms abdominal coarctation should be included in the differential diagnosis.

Acute Disease↗
PubMed1996

[Balloon mitral valve commissurotomy in pregnancy].

HISTORY AND CLINICAL FINDINGS: A 31-year-old woman with known postrheumatic mitral valve stenosis developed for the first time left heart failure in the 19th week of her fifth pregnancy. After intensive drug treatment she was in stage 3 (New York Heart Association classification). Apart from that the patient was in a good general condition and obstetrical status was according to the estimated duration of pregnancy. Auscultation revealed an apical diastolic murmur and mitral opening snap. INVESTIGATIONS: Echocardiography demonstrated a mitral valve opening area of 0.85 cm2 (pressure-half time method); the mean gradient was 19 mm Hg. TREATMENT AND COURSE: Because of the severity of the findings a percutaneous transvenous balloon valvotomy (according to Inoue) was performed in the 27th week of pregnancy, after careful lead shielding of abdomen and pelvis. Radiological screening time was 10 min. The invasively measured transvalvar pressure gradient was reduced from 28 to 4 mm Hg, echocardiographically determined mitral opening area increased to 1.5 cm2. Delivery was induced in the 36th week of pregnancy because of third-degree renal pelvis congestion. A healthy child, weighing 2850 g was delivered vaginally. CONCLUSION: High-grade symptomatic mitral stenosis can, if necessary, be treated with a low-risk to mother and child by percutaneous balloon valvotomy.

Adult↗