Obstetric complications and twin studies of schizophrenia: clarifications and affirmations.
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OBJECTIVE: To determine the outcome of trial of labour after two caesarean sections. DESIGN: Prospective observational study. SETTING: Maternity and Children's Hospital, Riyadh, Saudi Arabia. SUBJECTS: Women with two previous caesarean sections considered suitable for a trial of vaginal delivery. MAIN OUTCOME MEASURES: The rates of vaginal delivery, scar dehiscence, uterine rupture and associated complications among 115 women with two previous sections who underwent trial of labour were compared with 1006 women with two previous sections who did not have a trial of labour. RESULTS: Trial of vaginal delivery was requested by 230 out of 1136 women (20%) who had two previous caesarean sections. Of the 115 women accepted for the trial, 103 (89%) were delivered vaginally. Labour started spontaneously in 78 (68%) of the 115 women and was induced with prostaglandin (PGE2) in the remaining 37. Augmentation of labour with oxytocin was required in 32 (28%) of the trial labour group. There were no scar dehiscences among the women delivered vaginally. There was one scar dehiscence and one woman required hysterectomy after failed trial of labour, a frequency comparable to the occurrence of these complications in women who did not have a trial of labour. CONCLUSION: A trial of labour in selected patients with two previous caesarean sections appears a reasonable option.
OBJECTIVE: To evaluate whether pregnancies with infants affected by congenital heart defects are associated with adverse obstetric and perinatal outcome. STUDY DESIGN: In a prospective population-based cohort study from Sweden (1992-2001), 6346 singleton pregnancies with infants affected by congenital heart defects were, after suitable adjustments, compared to all delivered women. RESULTS: The prevalence of cardiovascular defects was 9.1 per 1000 births. Among them, mothers of 6346 infants (71%) had information on maternal smoking habits and maternal height and weight in early pregnancy that enabled the calculation of BMI. All cases with known chromosomal abnormalities and/or maternal pre-existing diabetes were excluded. Eighty-four percent (n=5338) had an isolated cardiovascular defect. Severe types occurred in 21.7% (n=1378). In the group of pregnancies with infants affected by congenital heart defects as compared to all delivered women, there was an increased risk of the following outcomes (adjusted OR (95%CI)): pre-eclampsia (1.21 (1.06-1.37)), cesarean section (1.91 (1.79-2.03)), instrumental delivery (1.21 (1.10-1.34)), pre-term delivery (2.58 (2.39-2.79)), small-for gestational age (1.96 (1.77-2.16)), meconium aspiration (1.51 (1.28-1.77)), and fetal distress (1.38 (1.17-1.63)). CONCLUSIONS: Pregnancies with infants affected by congenital heart defects are associated with several obstetric and neonatal complications.
On the cross histotopographic sections of 76 cords individual differences in the location of two arteries and veins of cord have been studied. The data are obtained on the changes of morphometric parameters of cord in normal and complicated pregnancy (obesity, neurocirculatory dystonia in hypertension type and miscarriages).
A case of conglutinatio orificii uteri externi is reported. Aetiology and pathogenesis of this rare complication of birth are discussed.
BACKGROUND: Uncomplicated uterine perforation has been considered a benign event. Since the advent of operative hysteroscopy, there have been several reports of uterine rupture during pregnancy in patients who have undergone that procedure when complicated by known or unsuspected uterine perforation. Large fundal defects without rupture have also been reported. CASE: A 23-year-old, white woman was admitted for labor induction at 42 weeks' gestation. After an unsuccessful attempt at labor induction, a cesarean section (C/S) was performed. At that time a large (5-cm) fundal defect was noted. A thorough history suggested that the defect was probably the result of unsuspected perforation of the uterus during dilatation and currettage for a late first-trimester fetal death. A follow-up hysterosalpingogram was done and consultation obtained regarding future management. A course of expectant management with C/S prior to the onset of labor was advised. Three years later, after an uncomplicated pregnancy, a repeat C/S was done at 38 weeks' gestation. CONCLUSION: Patients with a history of operative hysteroscopy or difficult curettage may have sustained known or unsuspected perforations of the uterus with subsequent scarring or defect, placing them at some risk of uterine rupture during pregnancy. Patients should be counseled regarding these risks, and assessment by hysterography might be helpful.
Shoulder dystocia, uterine inversion, and prolapse of the umbilical cord are three uncommon complications of the intrapartum period. These complications share several common characteristics in that they are rare, difficult to predict, and can result in significant morbidity and mortality. This article describes the etiology, predisposing factors, and methods of management of these complications.
Infantile colic (IC) is a distressing condition with an unclear etiology. A prospective trial was undertaken to study the hypothesis that medication during labor increases the risk of IC. Of 365 singleton deliveries, 70 (19%) developed IC. The factors associated with a significantly increased occurrence of IC were: a "psychological" complication of pregnancy, a sibling with a history of IC, a bad subjective experience of pregnancy and second parity. No significant association to "true" obstetrical complications or labor occurrences (breech, vacuum extractor, cesarean section, shoulder dystocia, pudendal block, epidural analgesia, general anesthesia or intravenous Syntocinon) was found. Modern management of labor does not increase the risk of IC. Prevention of IC is therefore achieved by psychological support to the pregnant women in the risk groups, and not by depriving her of necessary obstetrical management or pain relief.
141 forceps deliveries were studied. The frequency, number and type of complications were evaluated. Decreased number of forceps delivery and relatively high risk of complications in mothers and neonates were indicated. More then half of examined women in childbirth had various injuries of their birth canal. About 30% of new-borns were born with different types of birth's complications. Our results indicate that after forceps delivery the women and new-borns require special care in the perinatal period due to relatively high risk of serious complications.