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PubMed2006

In vitro evaluation of the susceptibility of endodontic pathogens to calcium hydroxide combined with different vehicles.

The aim of this study was to investigate in vitro the antimicrobial activity of calcium hydroxide [Ca(OH)2] in combination with different vehicles against endodontic pathogens. For such purpose, a broth dilution test was performed. Pastes were prepared with Ca(OH)2 powder and the following vehicles: sterile water, glycerin, camphorated monochlorophenol (CMCP), CMCP + glycerin, polyethyleneglycol and CMCP + polyethyleneglycol. The time required for the pastes to produce negative cultures against the tested microorganisms was recorded and analyzed statistically using the Kruskal Wallis test at 5% significance level. Timing for pastes to eliminate the aerobic and facultative anaerobic microorganisms ranged from 6 to 24 h, while strict anaerobic microorganisms were inhibited within 30 s to 5 min. Microbial susceptibility, ranked from weakest to strongest, can be presented as follows: Enterococcus faecalis (the most resistant microorganism), Candida albicans, Staphylococcus aureus, Porphyromonas gingivalis, Porphyromonas endodontalis and Prevotella intermedia (the last two microorganisms required the same time to be eliminated). In conclusion, calcium hydroxide pastes needed more time to eliminate facultative than anaerobic microorganisms. These findings suggest that the antimicrobial property is related both to paste formulation and to microbial susceptibility.

Anti-Bacterial Agents↗
PubMed2006

Effect of eugenol-based endodontic cement on the adhesion of intraradicular posts.

The present study evaluated, in vitro, the influence of an eugenol-based endodontic sealer (EndoFill) on the adhesion of intra-radicular posts cemented with a resin-based cement (Enforce) ou a zinc phosphate cement. Twenty-four single-rooted maxillary canines were divided into 2 groups (n=12) and obturated with either gutta-percha points plus EndoFill or gutta-percha points alone (no cement). In each group, half of intracanal posts (n=6) were cemented with Enforce resin-based cement and half with zinc phosphate cement. Specimens were submitted to pull-out test in an Instron machine and tensile force was applied at a crosshead speed of 0.5 mm/min until post dislodgement. The maximum forces required for post removal was recorded (N) and means were submitted to statistical analysis by Kruskal-Wallis test (p<0.01). Posts cemented with zinc phosphate cement were significantly more retentive (353.4 N) than those cemented with Enforce (134.9 N) (p<0.01). Regarding the influence of the eugenol-based cement (EndoFill) on post retention, there was statistically significant difference (p<0.01) only between the groups cemented with Enforce, i.e., in the canals filled with EndoFill + guta-percha there was lower bond strength than in the canals filled with gutta-percha points alone (101.5 and 168.2 N, respectively). In conclusion, the zinc-phosphate-based cement showed greater post retention than the resin-based cement. The findings of this study suggest that the eugenol-containing sealer interfered with the adhesive properties of the resin-based cement.

Dental Cements↗
PubMed2003

Cervical shaping in curved root canals: comparison of the efficiency of two endodontic instruments.

The aim of this study was to determine the removal of dentin produced by number 25 (0.08) Flare files (Quantec Flare Series, Analytic Endodontics, Glendora, California, USA) and number 1 e 2 Gates-Glidden burs (Dentsply - Maillefer, Ballaigues, Switzerland), in the mesio-buccal and mesio-lingual root canals, respectively, of extracted human permanent inferior molars, by means of measuring the width of dentinal walls prior and after instrumentation. The obtained values were compared. Due to the multiple analyses of data, a nonparametric test was used, and the Kruskal-Wallis test was chosen. There was no significant difference between the instruments as to the removal of dentin in the 1st and 2nd millimeters. However, when comparing the performances of the instruments in the 3rd millimeter, Flare files promoted a greater removal than Gates-Glidden drills (p > 0.05). The analysis revealed no significant differences as to mesial wear, which demonstrates the similar behavior of both instruments. Gates-Glidden drills produced an expressive mesial detour in the 2nd and 3rd millimeters, which was detected trough a statistically significant difference in the wear of this region (p > 0.05). There was no statistically significant difference between mesial and lateral wear when Flare instruments were employed.

Dental Instruments↗
PubMed2004

Natural medicaments in endodontics -- a comparative study of the anti-inflammatory action.

The objective of this study was to evaluate the irritant potential of propolis, Casearia sylvestris, Otosporin and saline solution (control). Twenty-eight male Wistar rats were selected, anesthetized and four experimental sites were designed on their backs. Injections of 2% Evans blue were intravenously administered in the lateral caudal vein and 0.1 ml of the tested solutions was injected intradermally into the experimental sites. The animals were killed 1/2, 1, 3 and 6 hours after the injection of the solutions. Each piece of skin containing the lesion was immersed in formamide and incubated at 45 masculine C for 72 h. After filtration, optical density was measured in a spectrophotometer. Data were statistically analyzed by a 2-way non-parametric test. The highest values of extracted dye were observed at 3 hours characterizing a peak in the inflammatory process. Propolis was the least irritant solution. The natural medicaments tested in this study may be a valuable alternative for endodontic treatment.

Animals↗
PubMed2004

Endodontic-periodontal locally delivered antibiotics.

Endodontic pathology is a bacterial disease. It is well established that periapical disease is the result of bacteria, their product, and the host response to them. Periradicular disease will occur after microorganisms and their metabolic products affect the periradicular tissue. Aim of using antibiotics as part of a treatment regimen is to achieve, within the periodontal environment, a concentration of the drug that is sufficient either to kill (bactericidal) or arrest the growth (bacteriostatic) of pathogenic microorganisms. There are two possible approaches to improve the drug action: sustained and controlled drug release to reduce or eliminate side effects by improving the therapeutic index and site-specific drug delivery to minimize systemic effects. These two strategies have been explored by the association of drugs with different vehicles, either naturals or synthetics. A wide variety of specialized local delivery systems (i.e.intrapocket devices) have been designed to maintain the antibiotic in the GCF (gingival crevicular fluid) at a concentration higher than the MIC (minimum inhibitory concentration). Fibres, films, strips and microparticles made of biodegradable or non-biodegradable polymers have been reported as effective methods to administer antibacterial agents for periodontal therapy. Together with these solid devices, semisolid adhesive or non-adhesive formulations have also been proposed.

Anti-Bacterial Agents↗
PubMed2005

Endodontic management of an impacted premolar.

This report demonstrates a simple endodontic solution to an interdisciplinary case of a patient with multiple gene deficiencies. An adolescent patient presented with an impacted premolar that could not be extracted due to high-risk conditions. A suspicious degree of radiolucency around the crown was clinically diagnosed as dentigerous cyst. The treatment dilemma and implementation are discussed. This case report offers a different treatment option for impacted teeth when significant differential diagnosis of a pericoronal lesion dictates treatment.

Adolescent↗
PubMed1999

Periodontic-endodontic lesions.

Lesions of the periodontal ligament and adjacent alveolar bone may originate from infections of the periodontium or tissues of the dental pulp. This review focuses on the relationship of lesions of endodontic origin with lesions of periodontal origin and their classification.

Dental Pulp Diseases↗
PubMed1984

Endodontic complications following periodontal and prosthetic treatment of patients with advanced periodontal disease.

A retrospective analysis was carried out to determine the frequency and onset of endodontic complications occurring in 52 patients treated for advanced periodontal disease. Comparisons were made between teeth which, following periodontal treatment, were used as abutments in fixed prosthetic reconstructions and nonabutment teeth. The study included 672 teeth with initially vital pulps (255 abutment teeth and 417 nonabutment teeth). The observation period varied from 4 to 13 years with a mean of 8.7 years. Pulpal necrosis including periapical lesions developed with a significantly higher frequency in abutment teeth than in nonabutment teeth (15% vs. 3%). The majority of these lesions did not appear until several years following the completion of active treatment. Conceivable reasons for the development of pulpal necrosis in teeth subjected to combined periodontal and prosthetic treatment are discussed.

Adult↗
PubMed1993

Radiographic attachment in periodontitis-prone teeth with endodontic infection.

The purpose of the present investigation was to examine the influence of a root canal infection on radiographic attachment. In addition, influence of the quality of the root fillings as well as the size of the periapical radiolucencies were studied. The investigation was conducted as a retrospective study on a consecutive referral population. The periapical conditions in endodontically-involved single-rooted teeth from a selected patient sample were correlated to the periodontal status of the teeth. Teeth with periapical lesions were found to have lost significantly more radiographic attachment, approximately 2 mm. A comparison between pocket depth in teeth with and without periapical pathology consistently showed that periapical pathology was significantly correlated to an increased pocket depth, also after adjusting for differences in radiographic attachment. It was concluded that periodontitis-prone teeth run a significantly higher risk of losing periodontal attachment if a root canal infection is also present and evident as a periapical radiolucency.

Adult↗
PubMed1993

Localized osteomyelitis secondary to endodontic-implant pathosis. A case report.

This case report documents the placement of a single implant fixture in an incisor extraction socket, with the adjacent lateral incisor developing periapical pathosis within 2 weeks. This root-end inflammatory process proceeded to communicate with the surface of the implant fixture. Although endodontic therapy was performed within one week on the devitalized tooth, and extensive osteomyelitis developed around the implant. Three weeks after placement, the fixture had to be removed. The osteotomy site appeared to be healing uneventfully during the one month follow-up period. Seven possible causes for this occurrence are discussed.

Dental Implantation, Endosseous↗
PubMed1995

Treatment of an endodontic perforation with a restoration and a root coverage gingival graft.

This case report describes the treatment of a perforation on the facial surface of the maxillary right central incisor made during endodontic therapy. Treatment of this highly visible area required a creative approach to therapy. The perforation was repaired with an amalgam restoration. A connective tissue with partial thickness double pedicle graft was used to replace missing periodontal structures, cover the exposed root surface, and obscure from view, as much as possible, the amalgam restoration placed in the perforation. This unconventional therapy is offered as a possible treatment option when few or no other acceptable options exist.

Adult↗
PubMed2005

[Significance of crown-down root canal preparation technique in endodontic therapy by using the hydroxylapatite sealer].

AIM: To evaluate the crown-down preparation technique, and the use of hydroxylapatite based material for the definitive root canal obturation. METHODS: The investigation included 20 single-canal roots with chronic periapical inflammatory lesion. Biomechanical medicamentous canal preparation was done using the double-flared technique with balanced force, and the obturation was performed with hydroxylapatite sealer (unicone technique). Clinical and radiographic check-up performed 12 months after the treatment, used the following parameters: pain, swelling, percussion and palpation sensitivity, and the presence of fistula. RESULTS: The obtained results showed a successful treatment in 18 cases, while in the 2 cases the treatment failed. CONCLUSION: These findings suggested that the crown-down preparation technique efficiently cleaned and shaped the root canal, and that the hydroxylapatite-based material created the homogenous and hermetic root canal obturation, so this methodology could be recommended for the endodontic therapy.

Adolescent↗
PubMed2006

Methodologies for assessment of apical and coronal leakage of endodontic filling materials: a critical review.

Apical leakage continues to be a topic of great interest, because in spite of the advances in Endodontics, clinical failures still occur. Most failures are probably attributed to the proliferation of bacteria that remain viable after chemical-mechanical preparation and cause periapical tissue irritation. Coronal leakage has aroused researchers' interest over the last few years, since canals may be re-contaminated after loss of coronal sealing or fracture of the remaining tooth. In this review, the various methodologies used for assessing root canal sealing capacity are critically analyzed, as they are not standardized, which makes it difficult to compare the results obtained when different methodologies are used, even though the same substrate is being assessed.

Bacteria↗
PubMed1982

Failures and healing in endodontically treated non-vital anterior teeth with posttraumatically reduced pulpal lumen.

The aim of the present investigation was to assess the frequency of technical failures as well as the 4-year results of endodontic treatment in non-vital incisors with post-traumatically reduced pulpal lumen. In 54 teeth the smallest width of the root canal was measured and classified as 0. less than or equal 0.1, greater than 0.1- less than or equal to 0.2 or greater than 0.2 mm. The total frequency of failures was 20%. In upper incisors it was 15-17% in the classes up to a root canal width of 0.2 mm. In lower incisors with no or only partially visible root canal it was 71% and in the class up to 0.1 mm 10%, the difference being significant at the 5% level. The total frequency of healing after 4 years was 80%, while in teeth with a technical failure at the time of treatment the frequency was 50%. The difference between the group without and that with technical failures was statistically significant at the 5% level.

Adolescent↗
PubMed1985

Bacteriological studies on endodontic paper points.

Four brands of endodontic paper points were subjected to tests for sterility, antibacterial activity, and suitability as vehicles for bacteriological sampling procedures. No brand showed growth in the sterility assay. One brand showed weak but reproducible antibacterial activity. Recovery of viable bacteria after absorption into the points varied and appeared to depend both on the brand of point and on the bacterial strain used. One brand appeared ineffectual for clinical bacteriological sampling procedures.

Bacteria↗
PubMed1993

Cusp fracture of endodontically treated posterior teeth restored with amalgam. Teeth restored in Denmark before 1975 versus after 1979.

The aim of the present study was to analyze the frequency and the severity of cuspal fracture for posterior teeth endodontically treated by 91 Danish dentists and restored with amalgam either before 1975 or after 1979. A database from a previous study was analyzed (1584 teeth with an MO, a DO, or an MOD amalgam restoration without cuspal overlays). Teeth restored before 1975 had a significantly lower frequency of cusp fracture than teeth restored after 1979. Moreover, when comparing the frequency of subcrestal fractures, that of the second group (after 1979) was more than twice as high as that of the first group (before 1975). Two factors with a bearing on these findings changed in the time period 1975-1979; the high-copper amalgams took over in Denmark, and the use of Gates-Glidden burs to achieve straight-line access to the root canal was introduced. It is suggested that the weakening of the coronal part of the root, caused by the use of Gates-Glidden burs, and the expansion and low creep of high-copper amalgams may be two of the reasons for the increased frequency and severity of cuspal fracture found in the past decade in Denmark.

Bicuspid↗
PubMed2006

Stress analysis of endodontically treated anterior teeth restored with different types of post material.

Finite element analysis was performed to evaluate stress distribution in maxillary central incisors treated endodontically and restored with a post and an all-ceramic crown. Tensile stress at tooth root was analyzed using two-dimensional finite element models with different post diameters and lengths. One post length was 1/3 of the root (short), while the other was 2/3 of the root (long); one post diameter was 1/3 of the root (narrow), while the other was 2/3 of the root (wide). The following combinations were used for posts and cores: gold alloy cast post and core, commercial stainless steel post and resin core, and fiber post and resin core. Results showed that the fiber post produced less stress on the root dentin around the post tip than did the metal posts. This finding thus suggested that to reduce the stresses that cause root fracture, a long, thin fiber post should be used.

Dental Stress Analysis↗