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PubMed1951

Irradiation treatment of lymphoid hyperplasia of the nasopharynx.

Irradiation is useful in the destruction of hypertrophied lymphoid tissue which cannot be surgically removed.Beta, gamma and roentgen rays have been used for this purpose. With beta rays, surface tissue must be subjected to relatively high dosages if effective radiation is to be delivered to deeper-lying tissues. This disparity is less when gamma rays are used, less still in the case of x-rays. With the possibilities of permanent damage considered, choice of method depends upon the location and extent of the excess lymphoid tissue to be destroyed and the mechanical difficulties of reaching it with effective irradiation without hazard to intervening or surrounding tissue.

Beta Particles↗
PubMed1992

[Calculation algorithm of three-dimensional absorbed dose distribution due to in vivo administration of nuclides for radiotherapy].

In the in vivo administration of radionuclides for radiotherapy including radioimmunotherapy, an algorithm is proposed for the purpose of calculating three-dimensional absorbed dose distributions of tumors and adjacent tissues, and neighboring organs. The absorbed dose distribution due to the algorithm is given by convolution of the three-dimensional dose matrix for a unit cubic voxel containing unit cumulated activity, with the three-dimensional matrix of the cumulated activity distribution given by the same voxel size above. The dose calculation algorithm does not depend upon the source size, the source shape, and the nonuniform and irregular activity distribution. In addition, it can exceedingly decrease computation time compared to other calculation algorithms. Computer simulations were performed using the MIRD thyroid phantom for 32P, 90Y, 131I, 186Re, and 188Re that appear promising for radioimmunotherapy, and their results verified the validity of the proposed calculation algorithm and high accuracy of the calculations.

Algorithms↗