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PubMed2002

[Between dermatoses and enteropathies].

A series of gastro-intestinal diseases exhibits some connection with various cutaneous lesions. Some skin manifestations are clinically or histologically evocative, while others lack specificity. These manifestations can occur in overt digestive disease or be the clue for a silent one. A careful skin examination can thus reveal some inflammatory or neoplastic diseases of the gastro-intestinal tract, a malabsorption syndrome or food intolerance.

Acrodermatitis↗
PubMed2002

Characterization of Borrelia burgdorferi sensu lato strains isolated from human material in Slovenia.

The aim of the study was to assess genotypic and phenotypic diversity among a large number of clinical isolates of Borrelia burgdorferi sensu lato obtained from patients in Slovenia. Plasmid profiles and species identification were determined by PFGE, protein profiles by SDS-PAGE. Of 706 B. burgdorferi sensu lato human isolates 599 (85%) were found to be B. afzelii, 101 (14%) B. garinii and six (1%) B. burgdorferi sensu stricto. The vast majority of strains (605; 86%) were isolated from skin, 58 (8%) from blood, and 43 (6%) from CSF. When analysed by RFLP, B. afzelii strains were unique, while heterogeneity was found within B. garinii and B. burgdorferi sensu stricto species. An unusual plasmid content was found in 52/706 (7%) isolated strains, more often in B. garinii than in B. afzelii strains. A plasmid dimer was found in B. afzelii and B. garinii strains, whereas multiple copies of the large plasmid were associated nearly exclusively with B. garinii strains. Analysis of protein profiles revealed that OspA and OspB are expressed more often by B. afzelii strains, and OspC by B. garinii strains. Heterogeneity of Borrelia strains may play a significant role in the virulence and pathogenesis of the infection. Differences in antigenic components have an important impact on serological testing and vaccine development.

Acrodermatitis↗
PubMedDate not supplied

Acroangiodermatitis of amputation stump.

Acroangiodermatitis is an angioproliferative disease characterized by pseudosarcomatous papules and plaques. It is often associated with different disorders like: chronic venous insufficiency, artero-venous malformations, artero-venous shunts, paralysed limb. In the case of amputation stumps the traumatic and suctional stimula may be the cause of this reactive pathology. We describe a case of acroangiodermatitis in an above-knee amputation stump in a 48-year-old-female affected by Down's syndrome.

Acrodermatitis↗
PubMed2003

Viral exanthems.

Viral exanthems are mostly associated with self-limited diseases. However, in some cases diagnosis of an exanthem may be crucial to patients and their contacts. Certain exanthems have fairly characteristic morphology, but in many cases an accurate diagnosis cannot be made on the basis of morphology alone. Historical factors may be helpful when evaluating these patients, specifically their disease contacts, immunization record, previous exanthematous illnesses, and associated prodromal symptoms. Some illnesses are seasonal and this knowledge may be useful. This manuscript reviews a number of common childhood exanthems. We included the most common viral exanthems encountered by primary-care physicians and dermatologists.

Acrodermatitis↗