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Validation of an item-reduction short form of the Stanford-Binet Intelligence Scale: Fourth Edition with college students.

This study investigated the comparability of item-reduction and subtest-reduction short forms of the Stanford-Binet Intelligence Scale: Fourth Edition (SB:IV) with the complete battery in a sample of college students. All item-reduction SASs were not significantly different from the full battery SASs. Correlations for corresponding SASs and subtests between the complete and short form were highly significant, and analyses of the short-form profile supported the interpretation of individual subtests. The subtest-reduction short-form SASs were significantly lower than both the item-reduction short form and the full battery. Thus, an item-reduction short form proved to be a more comparable estimate of the full battery composite than the subtest-reduction short form.

Adolescent↗

The relationship between psychometric intelligence and the five-factor model of personality in a rehabilitation sample.

WAIS-R and NEO Personality Inventory (NEO-PI) scores obtained from 85 rehabilitation clients of the Evaluation and Development Center of Southern Illinois University's Rehabilitation Institute were utilized to examine the relationship between psychometric intelligence and personality. Correlational analyses revealed that the NEO-PI Openness domain and its six facets significantly correlated with WAIS-R FSIQ, VIQ, PIQ, and 9 of the 11 subtests. Multiple regression analyses showed that the five NEO-PI domains accounted for significant proportions of WAIS-R, FSIQ, VIQ, and PIQ score variance. The NEO-PI Openness domain was found to be the best predictor of WAIS-R FSIQ, VIQ, and PIQ scores. The study concludes with a discussion of the meaning and implications of the findings and suggestions for future research.

Adolescent↗

Prospects of second generation artificial intelligence tools in calibration of chemical sensors.

Multivariate data driven calibration models with neural networks (NNs) are developed for binary (Cu++ and Ca++) and quaternary (K+, Ca++, NO3- and Cl-) ion-selective electrode (ISE) data. The response profiles of ISEs with concentrations are non-linear and sub-Nernstian. This task represents function approximation of multi-variate, multi-response, correlated, non-linear data with unknown noise structure i.e. multi-component calibration/prediction in chemometric parlance. Radial distribution function (RBF) and Fuzzy-ARTMAP-NN models implemented in the software packages, TRAJAN and Professional II, are employed for the calibration. The optimum NN models reported are based on residuals in concentration space. Being a data driven information technology, NN does not require a model, prior- or posterior- distribution of data or noise structure. Missing information, spikes or newer trends in different concentration ranges can be modeled through novelty detection. Two simulated data sets generated from mathematical functions are modeled as a function of number of data points and network parameters like number of neurons and nearest neighbors. The success of RBF and Fuzzy-ARTMAP-NNs to develop adequate calibration models for experimental data and function approximation models for more complex simulated data sets ensures AI2 (artificial intelligence, 2nd generation) as a promising technology in quantitation.

Artificial Intelligence↗

Normal intelligence in two children with Carpenter syndrome.

Previous reports have noted a constant association between the Carpenter syndrome (acrocephalopolysyndactyly, type II) and mental retardation. We report two patients with this condition with normal intelligence. These observations indicate that mental deficiency is not necessarily a component of the Carpenter syndrome and that early surgical correction of the craniosynostoses may improve the chances of normal mentality.

Acrocephalosyndactylia↗

Borderline normal intelligence in the Smith-Lemli-Opitz (RSH) syndrome.

We report two sibs with the Smith-Lemli-Opitz (RSH) syndrome and intelligence in the borderline normal range. The proposita has all the features of the syndrome; however, her brother shows fewer signs, indicating that considerable variability of expression may exist for this autosomal recessive trait. Nearly all previous cases had severe to profound mental retardation. The incidence of the syndrome in British Columbia is approximately 1/40,000 live births, giving a heterozygote frequency of about 1/100.

Abnormalities, Multiple↗

Familial microcephaly with normal intelligence, immunodeficiency, and risk for lymphoreticular malignancies: a new autosomal recessive disorder.

We describe nine patients with an apparently new genetic disorder characterized by: microcephaly with normal intelligence; "bird"-like facial appearance; cellular and humoral immune defects; and increased risk for lymphoreticular malignancies. The postmortem findings of five patients are described. Chromosome instability appears not to be a component of the disorder. The occurrence in three pairs of sibs and isonomy in another family suggests autosomal recessive inheritance.

Child↗

Johanson-Blizzard syndrome with normal intelligence.

We report a brother and sister with apparent Johanson-Blizzard syndrome and normal intelligence. There is a wide range of intellectual abilities of persons with Johanson-Blizzard syndrome. No phenotypic predictors of ultimate intellectual function were found in the literature.

Abnormalities, Multiple↗

Maternal effect on intelligence in fragile X males and females.

If the mother is the fragile X gene carrier, her daughters (and sons) with the mutation are at high risk of mental retardation. If the father is the (clinically unaffected) carrier, his daughters are normal. This is strong evidence for a maternal effect. The decreased penetrance and variable expressivity in fra(X) offspring of carriers could be related, at least in part, to variabile expression or availability of some maternal factor between pregnancies. We hypothesize a maternal effect in fra(X), with variability in intelligence of heterozygotes and hemizygotes mediated mainly by the maternal uterus or placenta by virtue of different patterns of lyonization in those tissues between pregnancies. If the mother is a carrier, the maternal placenta could develop with a skewed proportion of the normal or the fra(X) genetically active. Each female or male embryo could be exposed to very different environments with respect to genetic activity of the fra(X) chromosome, depending on the site of implantation within the uterus. If the father contributes the fra(X), the intrauterine environment is invariably normal and so are the daughters. Modifiers of the intrauterine effect could include lyonization patterns in tissues of the carrier fetus, and preferential inactivation of the paternal X in extra-embryonic tissues. The ultimate phenotype of the developing heterozygote and hemizygote may be determined by a threshold effect and interaction between the maternal genotype, the placental genotype, and the fetal genotype. The possibility of maternal effect is testable and has implications for treatment.

Dosage Compensation, Genetic↗

Trisomy 18 mosaicism in an adult with normal intelligence.

A healthy 30-year-old woman was discovered unexpectedly to have trisomy 18/normal chromosome mosaicism. She was ascertained because of a history of three spontaneous abortions following the birth of a healthy son. Trisomy 18 was present in 18% of her lymphocytes and 2% of her cultured skin fibroblasts. She had several minor malformations associated with trisomy 18 syndrome. She is, to our knowledge, the first person who has clinical stigmata of trisomy 18 but has normal intelligence and leads a normal family life.

Abortion, Habitual↗

Variable expression of the fragile X syndrome in heterozygous females of normal intelligence.

The cognitive, linguistic and memory functions of non-retarded fragile X heterozygotes and matched controls were examined by a detailed protocol of neuropsychological measures in order to determine the incidence of specific learning disabilities in this subgroup, and to compare their performance profiles with those of control subjects (mothers of Down syndrome sons). There were no group differences in psychometric intelligence, but the heterozygotes scored significantly lower than controls on most academic achievement tests, as well as on language-based neuropsychological measures. By neuropsychological criteria, 8 of the 15 heterozygotes, but only one of the controls, exhibited performance profiles consistent with a diagnosis of specific learning disability, and similar to cognitive profiles commonly seen in individuals from the general population with developmental dyslexia.

Adult↗

Artificial intelligence. Expert systems for clinical diagnosis: are they worth the effort?

Modeling the decision-making processes of human experts has been studied by scientists who call themselves psychologists and by scientists who say they are students of artificial intelligence (Al). The psychological research literature suggests that experts' decision-making processes can be adequately captured by simple mathematical models. On the other hand, those in Al who are preoccupied with human expertise maintain that complex computer models, in the form of expert systems, are required to do justice to those same processes. The resultant paradox of simple versus complex decision-making models is investigated here. The relevant literatures in psychology and Al are reviewed and, based on these findings, a resolution of the paradox is offered.

Artificial Intelligence↗

Advances in molecular labeling, high throughput imaging and machine intelligence portend powerful functional cellular biochemistry tools.

Cellular behavior is complex. Successfully understanding systems at ever-increasing complexity is fundamental to advances in modern science and unraveling the functional details of cellular behavior is no exception. We present a collection of prospectives to provide a glimpse of the techniques that will aid in collecting, managing and utilizing information on complex cellular processes via molecular imaging tools. These include: 1) visualizing intracellular protein activity with fluorescent markers, 2) high throughput (and automated) imaging of multilabeled cells in statistically significant numbers, and 3) machine intelligence to analyze subcellular image localization and pattern. Although not addressed here, the importance of combining cell-image-based information with detailed molecular structure and ligand-receptor binding models cannot be overlooked. Advanced molecular imaging techniques have the potential to impact cellular diagnostics for cancer screening, clinical correlations of tissue molecular patterns for cancer biology, and cellular molecular interactions for accelerating drug discovery. The goal of finally understanding all cellular components and behaviors will be achieved by advances in both instrumentation engineering (software and hardware) and molecular biochemistry.

Animals↗

Comparison of the Peabody Picture Vocabulary Test-Third Edition and Wechsler Adult Intelligence Scale-Third Edition with university students.

This study examined the relationship between the Peabody Picture Vocabulary Test-Third Edition (PPVT-III) and Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) using 40 adults who ranged in age from 18 to 41 (mean age of 22 years). Participants were administered the PPVT-III and WAIS-III in counterbalanced fashion to control for order effects. Results revealed that the PPVT-III score was related to the WAIS-III Verbal IQ (VIQ) and Full Scale IQ (FSIQ) scores but unrelated to the Performance IQ (PIQ) score. In addition, analyses indicated that, while there were no significant differences between the PPVT-III score and WAIS-III mean FSIQ and PIQ scores, the PPVT-III mean score was significantly lower than the WAIS-III VIQ. Further analysis indicated that the PPVT-III adequately estimated WAIS-III FSIQ and VIQ scores for participants who were classified as Average or High Average on the WAIS-III. However, for participants in the Superior range, the PPVT-III tended to underestimate FSIQ and VIQ scores by approximately 10 points.

Adolescent↗

Resilience in relation to personality and intelligence.

Resilience is a construct of increasing interest, but validated scales measuring resilience factors among adults are scarce. Here, a scale named the Resilience Scale for Adults (RSA) was crossvalidated and compared with measures of personality (Big Five/5PFs), cognitive abilities (Raven's Advanced Matrices, Vocabulary, Number series), and social intelligence (TSIS). All measures were given to 482 applicants for the military college. Confirmatory factor analyses confirmed the fit of the five-factor model, measuring 'personal strength', 'social competence', 'structured style', 'family cohesion' and 'social resources'. Using Big Five to discriminate between well adjusted and more vulnerable personality profiles, all resilience factors were positively correlated with the well adjusted personality profile. RSA-personal strength was most associated with 5PFs-emotional stability, RSA-social competence with 5PFs-extroversion and 5PFs-agreeableness, as well as TSIS-social skills, RSA-structured style with 5PFs-conscientiousness. Unexpectedly but interestingly, measures of RSA-family cohesion and RSA-social resources were also related to personality. Furthermore, the RSA was unrelated to cognitive abilities. This study supported the convergent and discriminative validity of the scale, and thus the inference that individuals scoring high on this scale are psychologically healthier, better adjusted, and thus more resilient.

Adaptation, Psychological↗

Intelligent dialogue based on statistical models of clinical decision-making.

The independence Bayesian model has been used widely in computer programs designed to support clinical decision-making. A reasoning strategy has been developed to enable these programs to conduct clinically pertinent dialogue and explain their reasoning. It has been implemented in a program for the diagnosis of acute abdominal pain based on the Bayesian model of de Dombal et al. Several features of the dialogue design have been adopted from artificial intelligence research, including shared initiative and critiquing. The program adopts a flexible goal-driven strategy, attempting to confirm the clinician's diagnosis or rule out the likeliest alternative. Symptoms and signs are selected in order of their expected weights of evidence in favour of the hypothesized disease.

Abdomen↗

Intelligence and the frontal lobe: the organization of goal-directed behavior.

Basic to the study of individual differences is the concept of 'general intelligence' or Spearman's g. In this article we suggest that g is largely a reflection of the control functions of the frontal lobe. A series of experiments investigates a phenomenon we call goal neglect: disregard of a task requirement event though it has been understood and remembered. Subjectively it is as though the neglected requirement "slips the subject's mind." Previously described in frontal patients, we show that goal neglect can also be seen in some members of the normal population. In line with conventional distinctions between controlled and automatic processing, eliciting conditions for goal neglect include novelty, weak error feedback, and multiple concurrent task requirements. Under these conditions neglect is linked closely to g and extremely common after frontal lesions. Following many other models, we suggest that behavior in any task is structured by a set of action constraints or requirements, derived in part from verbal instructions and specified at multiple levels of abstraction. A frontal process of constraint or requirement activation is fundamental to Spearman's g.

Adult↗

Deficits in emotional intelligence underlying adolescent sex offending.

The present study investigated whether a battery of tests designed to measure different levels of emotional intelligence could differentiate adolescent sex offenders from a non-offender control group. Fifteen male adolescent sex offenders ranging in age from 14 to 17 years were recruited through Health and Community Services (VIC, Australia) and 49 non-offender males, matched for age, completed the battery. The battery comprised the Trait Meta-Mood Scale (TMMS), Davis' Interpersonal Reactivity Index (IRI), the Inventory of Interpersonal Problems (IIP-32), the Revised Toronto Alexithymia Scale (TAS-20) and the Openness to Feelings facet of the NEO PI-R. Discriminant analyses using all five tests showed that 89.9 per cent of the sample were correctly allocated their respective groups. Overall the sex offenders were higher on aggression and attention to feelings, less clear about their feelings and less capable to repair unpleasant moods and prolong positive ones. It was concluded that these findings could be the focus of treatment approaches for adolescent sex offenders.

Adolescent↗