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Incisor crossbite and repaired unilateral cleft lip and palate: changes in jaw movement and temporalis muscle activity before and after edgewise treatment--case report.

OBJECTIVE: To examine the changes in jaw movement and temporalis muscle activity of a patient with unilateral cleft lip and palate before and after edgewise treatment. DESIGN: Clinical case study. SETTING: University dental hospital, department of orthodontics. PATIENT: A 12-year 3-month-old male with incisor crossbite, molar malocclusion, and repaired unilateral cleft lip and palate who had completed first-phase orthodontic treatment. MAIN OUTCOME MEASURES: This patient was treated with an edgewise appliance. Jaw movement and temporalis muscle activity during the chewing of a hard gummy jelly were recorded at 2 kHz from the sixth to the twentieth stroke before edgewise treatment and after a retention period of 2 years. RESULTS: Optimum intercuspation of teeth was achieved. The reversed crossing jaw-movement pattern before treatment changed to a normal grinding after treatment. The posterior temporalis muscle on the chewing side exhibited an earlier burst than the contralateral one during chewing at the post-treatment stage, as is observed in cases with good occlusion. CONCLUSION: Improvement in the occlusion using an edgewise appliance is necessary for acquiring a good masticatory function in patients with incisor crossbite, molar malocclusion, and cleft lip and palate.

Child↗

Sensitivity of rat temporalis muscle afferent fibers to peripheral N-methyl-D-aspartate receptor activation.

The temporalis muscle is a common source of pain in headache and chronic craniofacial pain conditions such as temporomandibular disorders, which have an increased prevalence in women. The characteristics of slowly conducting temporalis afferent fibers have not been investigated. Therefore, the aim of the present study was to examine the characteristics of slowly conducting temporalis muscle afferent fibers and to determine whether these fibers are excited by activation of peripheral N-methyl-D-aspartate receptors. The response properties of a total of 117 temporalis afferent fibers were assessed in male and female rats. A majority of these fibers had high mechanical thresholds and slow conduction velocities (<10 m/s). The mechanical threshold of the temporalis afferent fibers was inversely correlated with afferent conduction velocity, however, no sex-related differences in mechanical threshold were identified. There were also no sex-related differences in N-methyl-D-aspartate-evoked afferent discharge. Indeed, injection of a high concentration (1600 mM) of N-methyl-D-aspartate into the temporalis muscle was necessary to evoke significant afferent discharge. Thirty minutes after the initial injection of N-methyl-D-aspartate into the temporalis muscle, a second injection of N-methyl-D-aspartate produced a response only about 50% as large as the initial injection. Co-injection of ketamine (20 mM) with the second injection of N-methyl-D-aspartate significantly decreased N-methyl-D-aspartate-evoked afferent discharge in both sexes. This concentration of ketamine is greater than that needed to attenuate afferent discharge evoked by injection of glutamate into the masseter muscle. These results suggest that unlike masseter afferent fibers, temporalis afferent fibers are relatively insensitive to peripheral N-methyl-D-aspartate receptor activation.

Afferent Pathways↗

[Temporalis myofascial flap: technique description and results in our patients].

INTRODUCTION: Surgical treatment of intraoral and maxillary sinus carcinomas requires a reconstructution of the defect. It is better to do it in one time in order to decrease the morbidity for the patient and the sanitary cost. The temporalis myofascial flap is used for reconstruction of oral cavity, skull base, periorbital region and maxilla because of its feasibility. MATERIAL AND METHODS: We describe the surgical technique and present our results of the reconstructions after total or partial maxillectomy using the temporalis muscle flap in 22 patients. RESULTS: No total necrosis of the flap was seen in any case, a partial necrosis was seen in four cases. CONCLUSION: The temporalis myofascial flap is an excellent choice for oral and maxillary reconstruction.

Adult↗

[Craniofacial growth under the influence of blood supply. 13. Local biomechanical aspects of bone morphogenesis].

The origin of formative forces is to be sought in genetically controlled growth processes. The forces generated by various system components are analyzed. The forces acting in mutual opposition can be illustrated by considering the brain as an intracranial force factor and the temporalis muscle as an external force factor. Apposition and resorption of bone is governed by the interaction between the stresses. The skull's primary growth centres such as the basicranial synchondroses must, like epiphyses of tubular bones, exert growth forces to overcome the restraining forces stemming from surrounding tissues. Growth can be suppressed by excessive counter-pressure, diverted by asymmetrically acting forces, and encouraged by the removal of suppressive forces.

Biomechanical Phenomena↗

Infratemporal approaches to nasopharyngeal tumors.

Twenty patients with neoplasms originating in the nasopharynx were operated using the infratemporal fossa approach with facial translocation (15 cases), the subtemporal-preauricular infratemporal approach (2 cases), and the transmandibular approach (3 cases). A craniectomy was also required in 14 cases. Fifteen tumors were malignant, while 5 were juvenile angiofibromas with infratemporal and intracranial extensions. Most of the lesions were large and involved multiple areas of the skull base. Tumor excision was total in all but 3 patients. Local flaps were utilized in all patients to seal the operative cavity and consisted of temporalis muscle flaps. The most frequent postoperative complications were wound infections and cerebrospinal leaks. Two patients died as a result of postoperative complications. To date, 1 patient has died from disease and 3 are alive with local or distant disease.

Adolescent↗

[Transzygomatic approach of the infratemporal fossa. Value and limits].

We report about one case of neurofibroma in the infratemporal fossa, which was treated surgically through a transzygomatic approach. Lowering the zygomatic arch with the masseter muscle and raising the coronoid process with the temporalis muscles provides a wide access to the infratemporal region without any mutilation. This way of approach can be widened anteriorly towards the orbital frame in order to reach lateral orbital lesions, and posteriorly towards the mastoideum to resect large tumors extending into the base of the skull. The transzygomatic approach seems to be particularly appropriate for the exeresis of benign tumors in the infratemporal region.

Facial Neoplasms↗

Modified temporalis muscle transfer for paralytic eyelids.

The major problems in paralytic eyelids are the inability to close the eye, lower lid sagging, and epiphora. The upper eyelid is responsible for most of the opening and closing of the eye, whereas a lower eyelid positioned properly against the globe is necessary for collection and flow of the tear fluid. Modification of temporalis muscle transfer, a classic technique, was planned to restore these functions selectively in paralytic eyelids. Twelve unilateral and one bilateral irreversible facial paralysis patients with different degrees of lagophthalmos and ectropion were included. Twice as much muscle mass (in thickness) to the upper eyelid than the lower was taken and passed submuscularly 5 to 6 mm away from the limbus for stronger motion of the upper eyelid, and a thinner muscle mass was passed subcutaneously beneath the lower cilia for longevity of the correction of ectropion and epiphora. Fixation of these strips was performed to the medial canthal ligament and 3 to 4 mm above it. The average duration of follow-up was 35.5 months. Excellent eyelid closure and correction of ectropion and epiphora were achieved with one procedure in all patients without creating a cosmetic deformity.

Adolescent↗

Reconstruction of discharging mastoid cavities using the temporalis myofascial flap.

Muscle obliteration of the troublesome mastoid cavity is one method of achieving a permanently dry ear, although long-term results are often disappointing. An operation is described, which is a modification of existing techniques and utilizes a temporalis myofascial flap. This procedure has been used on 46 discharging mastoid cavities and produced encouraging results. It provides a simple, safe and reliable solution to the problem.

Adult↗

[Human muscle dirofilariasis of difficult diagnosis].

A case of Dirofilariasis by Dirofilaria repens localized in the left temporalis muscle, in a 43-year-old woman, is described. It was acquired in South-western Sicily but became apparent in Pisa. It is the seventh case of human Dirofilariasis reported from this area, confirming the existence of an endemic focus. In spite of the numerous investigations to identify clinically the illness (needle-aspirate, Echography, CTScan) the diagnosis was possible only upon discovery of the nematode in the histological sections of the surgically removed nodule.

Adult↗

[Orbital exenteration associated with cavity reconstruction].

OBJECTIVE: A surgery was designed for the cosmetic improvement after orbital exenteration. METHODS: Exenteration associated with simultaneous or secondary orbital reconstruction was performed on 22 patients, including transplantation of temporalis muscle in 11 cases, temporoparietal fascia with vascular pedicle in 10 cases and latissimus dorsi myocutaneous free flap in one case. RESULTS: Except 7 patients who needed palpebral resection and orthopedic operation the second time, all of them were fitted well with ocular prostheses postoperatively and obtained satisfactory cosmetic results. CONCLUSION: Among the three methods of orbital reconstruction, the temporoparietal fascia transplantation is the best.

Adolescent↗

Temporalis muscle flap for craniofacial reconstruction after tumor resection.

Temporalis muscle flap provides a good solution for the reconstruction of craniofacial defects after tumor resection. Nine patients with complicated defects located at the upper two thirds of the face, anterior cranial base, or mastoid region are presented. Five patients had orbital exenteration, two with total maxillectomy and two with anterior craniofacial resection. Temporalis muscle flap provided profuse well-vascularized tissue for the obliteration of orbital exenteration and total maxillectomy cavities and coverage of surface defects. Cranial, oral, and nasal spaces were separated successfully in all patients. Temporalis muscle flap is a very reliable technique with low complication rates and few donor site problems. This safe and technically easy flap can be preferred for the reconstruction of craniofacial defects after ablative tumor surgery, especially in older and debilitated patients.

Aged↗

Surgical reconstruction of the contracted orbit.

Anophthalmic patients and patients afflicted with retinoblastoma incur severe deformity of the orbit. Treatment of the severely contracted orbit is very difficult, and patient satisfaction is often poor. Since 1988, we have performed temporalis muscle transfer and surgical expansion of the contracted bony orbit in 26 patients. Satisfactory results were obtained. Gradual expansion of the orbit was performed in case of congenital anophthalmic patients. The treatment should be established in multiplicity, among many methods available for contracted eye sockets, according to the degree of orbital deformity and the amount of residual conjunctiva. In case of severe deformity, volume expansion surgery and temporalis muscle transfer are necessary. If augmentation is required in the periorbital region, rib bone onlay graft must be performed. We were able to shorten the operative time by modifying the three-wall orbital expansion technique of Tessier and Wolfe to a more simplified method. Our observations show that our procedures achieved symmetry in both eyes in all patients, and there have been no remarkable complications.

Adult↗

Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats.

Previous studies have shown that jaw reflexes and activity patterns of the jaw muscles were modulated in the presence of jaw muscle pain. However, there is no study comparing the modulatory effects on the jaw reflexes induced by noxious stimulation to the jaw muscle. To clarify this, effects of the application of mustard oil (MO), an inflammatory irritant, into the temporalis (jaw-closing) muscle on (1) jaw-opening reflex evoked by tooth pulp stimulation (TP-evoked JOR) as a nociceptive reflex, (2) jaw-opening reflex evoked by inferior alveolar nerve stimulation as a non-nociceptive reflex and (3) jaw-closing reflex evoked by trigeminal mesencephalic nucleus stimulation as a proprioceptive reflex were investigated in anesthetized rats. The MO application induced suppression of all reflexes, and the effect on the TP-evoked JOR was more prominent than on the other reflexes. To elucidate the involvement of endogenous opioid system for the suppressive effect, a systemic administration of naloxone following the MO application was conducted. The MO-induced suppressive effect on the TP-evoked JOR was reversed by the naloxone administration. The results suggest that noxious stimulation to the jaw muscle modulate jaw reflexes particularly for the nociceptive jaw-opening reflex, and the modulatory effect includes both facilitatory and inhibitory aspects. The results also suggest that pain modulatory systems such as the endogenous opioid system play a crucial role in the suppression of the nociceptive transmissions related to nociceptive reflexes, and in some pathological states, defense reflexes may not be evoked properly.

Analysis of Variance↗

Surgical exposure of lateral orbital lesions using a coronal scalp flap and lateral orbitozygomatic approach: clinical experience.

BACKGROUND: The lateral extraconal compartment is a typical localization of intra-orbital tumours. With the exception of anterior lesions, which can be reached by a transconjuntival route, most of these tumours are currently approached through the classic lateral orbitotomy originally described by Kronlein. We present here our experience in the management of lateral orbital lesions, using a coronal skin flap, followed by subfascial dissection of the temporalis muscle. The procedure was intended to overcome the potential drawbacks associated with the classic transtemporal approach. METHODS: The approach was used in eleven patients harbouring bone lesions of the lateral orbital wall or intra-orbital lesion of the lateral extra-ocular compartment. The postoperative results were assessed using a simple cosmetic outcome scale, which evalutated the temporalis muscle trophism and the function of the frontotemporal branch of the facial nerve. RESULTS: All lesions were satisfactorily exposed. The subfascial dissection of the temporalis muscle is a key manoeuvre which, at the same time, abolishes the risk of injury to the frontotemporal branch of the facial nerve and provides a wide exposure of the lateral orbital wall. The cosmetic outcome was excellent in 9 patients and good in 2 patients. CONCLUSIONS: The reported technique is a convenient surgical option to approach lateral intra-orbital lesions, with a minimal cosmetic impact.

Adult↗

Medial portion of M. Temporalis and its potential involvement in facial pain.

We describe the morphology, functional capabilities, and clinical anatomical implications of the medial portion of the temporalis muscle. Although recognized in Brazilian, German, French, and Hispanic American textbooks of anatomy, this portion of the temporalis has been unappreciated in those published in England and the United States. Given its morphology, and functional anatomy as revealed in this paper, we conclude that the medial portion of the temporalis could entrap the maxillary nerve and its zygomatic branches inside the pterygopalatine fossa. On these bases we identify this portion of the temporalis as a possible factor in the etiology of some forms of tic douloureux.

Aged↗

Vascularized skull bone grafts in craniofacial surgery.

Vascularized skull bone grafts based on a pedicle of temporalis muscle have been used in 30 zygomatic arch and malar reconstructions, 1 mandible reconstruction, and 1 palate reconstruction. The surgical technique, complications, and postoperative results are reviewed. Technetium bone scans obtained within one week of operation confirm blood supply to the transferred bone. After a mean follow-up of 13 months, there is no evidence of bone graft resorption. We have used a team approach and careful surgical technique, and no serious complications have been encountered.

Adolescent↗

Gap junctional communication among motor and other neurons shapes patterns of neural activity and synaptic connectivity during development.

We are studying the functional roles of neuronal gap junctional coupling during development, using motor neurons and their synapses with muscle fibers as a model system. At neuromuscular synapses, several studies have shown that the relative pattern of activity among motor inputs competing for innervation of the same target muscle fiber determines how patterns of innervation are sculpted during the first weeks after birth. We asked whether gap junctional coupling among motor neurons modulates the relative timing of motor neuron activity in awake, behaving neonatal mice. We found that the activity of motor neurons innervating the same muscle is temporally correlated perinatally, during the same period that gap junction-mediated electrical and dye coupling are present. In vivo blockade of gap junctions abolished temporal correlations in motor neuron activity, without changing overall motor behavior, motor neuron activity patterns or firing frequency. Together with preliminary studies in mice lacking gap junction protein Cx40, our data suggest that developmentally regulated gap junctional coupling among motor and other neurons affects the activity in nascent neural circuits and thus in turn affects synaptic connectivity. Dynamic monitoring of dye coupling can be used to explore this possibility in normal mice and in mice lacking gap junction proteins during embryonic and neonatal development.

Action Potentials↗

[The pterygo-maxillary fossa (infra-temporal fossa). Topographical division. Methods of investigation. Transmandibular approach to the region of the pterygoids (author's transl)].

The pterygo-maxillary fossa, hidden behind the face under the base os the present time. The scanner has transformed the investigation of this region and offers the possibility of discovery of processes limited to the pterygo-maxillary fossa which was above all known as an area affected by the extension of tumour processes arising in the maxillary sinus of parotid. A topographical division of the pterygo-maxillary fossa is suggested on the basis of CT pictures and surgical approaches. The region of the pterygoids may be easily reached via a transmandibular, the technique of which is described.

Adult↗