Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “SELF MUTILATION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,621 records · Page 90Linked to original sources
PubMed1983

Clonidine potentiates drug induced self-injurious behavior in rats.

Caffeine and amphetamine have been regarded as dramatically dissimilar drugs, both structurally and behaviorally. However, both are stimulants and (under certain conditions) both produce self-injurious behavior in rats which is potentiated by clonidine. Rats were pretreated with various doses of clonidine prior to daily administration of caffeine. In another experiment, rats which had been implanted with continuous release amphetamine pellets were injected twice daily with various doses of clonidine. Clonidine produced a high rate of self-biting when combined with subthreshold doses of caffeine. Clonidine was less effective in potentiating amphetamine induced self-biting; the highest dose tested raised the incidence from 28 to 64%. Clonidine tended to decrease the incidence of behaviors other than self-biting. Thus although caffeine and amphetamine clearly do not have identical behavioral effects, there is increasing evidence that certain of their effects are mediated by similar mechanisms.

Amphetamine↗
PubMed1978

Self-inflicted bleeding and bruising.

Of 8 psychiatrically referred patients with bruises and bleeding, self-injury was admitted in 2 cases and the means of self-injury were discovered in 6. All the patients were fairly young, single or unhappily married females, with unresolved emotional problems, most commonly sexual. 22 of 43 female haematology outpatients showed no haemostatic abnormality and were though to be seeking attention.

Adolescent↗
PubMed1980

Oedeme bleu: a reappraisal.

The case-histories of four patients with self-induced lymphoedema show a distinctive organic syndrome, but the underlying mental mechanisms in these patients show no common thread other than an apparent wish to draw attention to an untreatable condition. A policy of non-intervention may reduce or limit the eventual disability.

Adult↗
PubMed1980

Oedème bleu.

Explore the source record for details and available documents.

Adolescent↗
PubMed1997

Fetal abuse.

The possible occurrence of fetal abuse in expectant mothers has received little attention in either clinical practice or in research. Five cases with reported fetal abuse are presented. Each case suffered from depression and four of the five women had unplanned pregnancies and had considered a termination of pregnancy. Other possible factors associated with fetal abuse included: denial of the pregnancy, ambivalence towards the pregnancy, previous postpartum depression, and relationship difficulties. Enquiry of possible fetal abuse in pregnant women should be made, particularly if a depressive illness is demonstrated. The relationship between fetal abuse and subsequent child abuse remains unclear.

Adult↗
PubMed2001

Self-inflicted anterior scleritis.

PURPOSE: To describe and clinically characterize a syndrome of self-inflicted scleritis. STUDY DESIGN: Case reports and literature review. METHODS: Two patients had persistent scleritis at presentation. Both did not respond to prescribed therapy, including systemic corticosteroids and immunosuppression. The first had unexplained, diffuse anterior scleritis and persistent linear keratoconjunctival abrasions after a work-related injury. Several objective indicators pointed to concealed noncompliance with medications. The second patient was a medical assistant with diffuse, unilateral anterior scleritis and unexplained visual loss. Systemic work-up was negative. She had pharmacologic mydriasis and keratoconjunctival abrasions at presentation. RESULTS: Systemic therapy was stopped in both patients. The first patient, who was in the process of requesting permanent disability status, showed persistent inflammation on each follow-up visit. The second patient improved with no further therapy after she was confronted with objective indicators of a self-inflicted condition. CONCLUSIONS: Although the presentation of self-inflicted scleritis can be similar to that of idiopathic or autoimmune anterior scleritis, the former may show additional findings of traumatic conjunctival and corneal abrasions. Indicators of self-inflicted etiology, of which malingering is one such entity, include evidence of concealed noncompliance with prescribed treatments and lack of response to potent antiinflammatory and immunosuppressive agents. Correct diagnosis including early psychiatric evaluation in all such cases, may help prevent unnecessary treatment and unjustified work-related compensation.

Administration, Topical↗
PubMed2003

Self-inflicted (factitious) conjunctivitis.

PURPOSE: To describe the diagnosis and management of self-inflicted factitious conjunctivitis in conscripted soldiers. DESIGN: Prospective, noncomparative, consecutive case series. PARTICIPANTS: Seventeen conscripted soldiers. METHODS: Soldiers with chronic conjunctivitis (>3 weeks) were referred by ophthalmologists, and cases of shorter duration were referred by primary-care physicians. All cases underwent thorough ophthalmic and systemic history and examination, as well as questioning regarding their military units, military duties, and social background. Exclusion criteria were any condition that may cause conjunctivitis. Inferior fornix specimen microscopy and culture and eye photography were performed in most cases. In cases suspected of self-inflicted conjunctivitis all medication, besides lubricant drops, was stopped. Underlying psychosocial problems were investigated and managed. Cases were followed for at least 3 months after resolution of the conjunctivitis, at which point the diagnosis was confirmed, and the case entered the analysis. MAIN OUTCOME MEASURES: Resolution of the conjunctivitis. RESULTS: Seventeen consecutive cases of self-inflicted conjunctivitis, 8 of long duration and 9 of short duration, were studied. All cases demonstrated inconsistent clinical findings. The ocular signs most suggestive of self-inflicted conjunctivitis were purulent discharge purposely left on the lashes and periorbital skin, discharge more severe than in conjunctival hyperemia, less conjunctival chemosis than in hyperemia, mainly inferior conjunctival involvement, and an uninvolved cornea. Five of the 8 chronic cases had significant underlying psychologic or social problems. Their conjunctivitis resolved only after their underlying problems were addressed. Two cases admitted introducing freshly scraped dental plaque into the lower conjunctival sac. In the remaining 15 the similarity of the clinical findings suggested that a similar method was used. CONCLUSIONS: In the context of a subject standing to gain by assuming the sick role and after exclusion of ocular pathology, self-inflicted conjunctivitis can be reliably diagnosed by noting the characteristic clinical profile. Effective management includes addressing the underlying psychologic and social problems.

Adolescent↗
PubMed1986

Ocular Munchausen's syndrome.

Patients with contrived histories and/or self-induced physical abnormalities (Munchausen's syndrome) are often successful in deceiving physicians. We recently cared for four patients with ocular Munchausen's syndrome. Self-induced ocular manifestations included voluntary nystagmus, subconjunctival hemorrhages, chronic orbital emphysema requiring exenteration, corneal alkali burns, erosions and ulcerations, and abscesses of the periorbital area. Correct diagnoses of ocular Munchausen's syndrome were made only after extensive medical and surgical investigations. Suggestions for evaluation and treatment will also be discussed.

Adult↗